Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 94313091

GI number: 94313091

Start: 746896

End: 749355

Strand: Direct

Name: resE [H]

Synonym: Rmet_4164

Alternate gene names: 94313091

Gene position: 746896-749355 (Clockwise)

Preceding gene: 94313090

Following gene: 94313094

Centisome position: 28.95

GC content: 67.72

Gene sequence:

>2460_bases
TTGGCGCCCAATAGAACTGACCTGCGCAGCGGTCAGTTCGACGCGGCCGAGCGGGAGGGCGCCCCGGGCGCCATGGGCTT
TCGTCGGCGCACGCGACTGGAGTGGGCGCTGCTCACCGCCGCCGTGCTGGTGATCGCCCTGGCCGCGTCAAGTTTCTCCT
GGTTCGAACGCGCGGACCTGGCCGTGTTGGACCTGGCCATCGTTGCCCAGGAGCACCCCGCGCGCAATGACATCGTGATC
GTCGCCATCGACGACGAAAGCATCGGCGTGATTGGCCGCTGGCCGTGGCGGCGCACGGTGCTTGCCGCGCTGGTGGACCA
GATCGGCGCTGACAATCCGCGTGCGATCGGCATCGATGTGATCCTGTCCGAACACGATATCCGTTATCCGTCCGACGACG
CCGAACTGGCGCGTTCCGTGGCGCGGTCCGGCAACGTAGTCTTGCCCATGGTCGGCGAGTCAGGATCGAGCGGCGCGCGG
CTGCGCGGCCCGATGGATGGCTTGCTGGCCCAGACTGGCCACATCAACATGATTGTGGATACCGATGGCGTGGCCCGACA
GGTGTATCTGCGCGAGGGCGATGGCGAAGGGCCGCCGGTCTGGCACTTCGCGGCCGCCATGGCGGCGCTGGGGCAGCACA
CGCCGGTGACAGCGGCGCAGTTCCGCAACGAACGCGCGGTACGCATGGATGGCGCGGGGTGGATCAGTCAGGACCGATTG
CGGATTCCGTTCGTCGGCCCCCCGGGGTCGTTCGCGCGCGTCTCTGTGCTGGATGTGCTTTCCGGCGAGGTCAGTCGCGG
CTACTTTCGCGACAAGTCCGTACTGATCGGCACCGTCGCCACCGGACTCGGCGATGTGTTCCCGACGCCGGTATCGCGCG
ATGGGCGCGCCATGAGCGGTGTCGAAATTCTGGCCAACACGCTGCAGGCGCTGCTCGATGGCACCGGCATCGTTACCGTG
CCCAAGCCCGTGGGCTGGCTCGGGACGATCCTGCCGGTGCTGCTGGCGGCCCTGGCGGCGTTGCGGTTCTCGCCGCGCAA
TGCGCTGCTCGCCACGGTGGCGATCGTCGCGGCGGTCGTCGGCACCAGTCTCTGCCTGCCGGGCAGTATGCATCTGTGGT
TTGCGCCGTCGGGTGCGGTGCTTGGCTGCATGATGGTCTACCCCCTCTGGAGTTGGCGGCGTCAGGAAGCCGCGCTCCGC
TTCCTGTCCGAAGAACTCGGGCGCCTGGCGCATGAGCCAGGCTTGCTGGCGGCGCCAGCCACGCGCATCGACCACTCGCT
CGACGGCCGGATGCAGGCGGTCTACGGCATGACCTCGCGCCTGCGCGACATGCGGCGCTTTCTGTCTGACGGACTGGAGA
GCCTGCCGGAAGCGACCGTGATCTGCAATCTCGATGGCGGCATTCTGGTGGCGAACCGGCGCGCGGTGGCGCTGGCGCCA
ACGATGCTCCAGGGGATCGACGGCGCGTACTATGCCAACGACCTGCGGTACATGCGCGGCAGCAATACGTACGGCGAGCT
AGGCCGCCCGGCGTTGCCCGACCTGATCGAGGCGATGTTCACGGTGGCGGGTCCGGGCCTGGCCTACTGGGACGCGCTGT
GCGGCGCGCTCGAAGGTGACGCGCCGGTGATGTCCTCGTCGGATTCGCATGGCGTGGAACTGACCACCGAGGACGGCCGG
CGCTATCTGTTGCATGGCGGGCCGCTGCATGGCGAGGCGGGGCGTCCCGCGGGCGTGATCGTCAGCCTGATCGACATTAC
CGCGATACGTCGCGCCGAACGCCAGCGCGAGCAGACACTGCATTTCCTGTCTCACGACATGCGTTCGCCGCAGGCGTCGA
TCCTGGCCCTGATCGACATGCAGTCACGCCCCGACCGTGCCTTGCCGCAGACCGAACTGCTCGGACGAATCGGCGAACAC
GCGCACCGCACGCTTGCCCTGGCCGACGATTTCATCCGGATTGCGCAGGCCGAATCGCAGAGCCTGACGTTTGCCGAGAC
CGACCTGACGCAGATCGTGCTCGACGCAACCGATGAAATGTGGGCGCTGGCCAAGGCGCGTGGGACCGAACTGCGGCTCG
ACATCGACGAGCAGGGGCCGAGGTTGCGCGTGGCGCCAGCCCTGCTGGCGCGCGCCATCACCAACCTGGTCAACAACGCC
ATCAAGTACAGCCCGTGCGGCACCGAAGTGACGGTGCGCCTGCGCAGGCTCGGCCCCTATATGGCGATCGAGGTATCCGA
TCAGGGGCCGGGCATCTCGCAAGACGCCCAGGCACGGCTGTTCCGGCCGTTCAGCCGAGTGCACGCGCATGGCGCCGATG
CGCCGTCTGGCAGCGGCCTGGGGCTTGTATTTGTGAAGACCGTGGCGGAGCGCCATGGCGGCCGGGTGATGGTTGCCAGT
GAAGTTGGCAAGGGCACGATGTTCTCCATCTGGTTGCCCCTGCGCAGCCGCGCGTCCTGA

Upstream 100 bases:

>100_bases
AGCGCGTTTTCCGCGCCACAGCGAATCGACCTGCAATCTGTGCTGCGTGATGGACAGGGTGCGGTGATTGTGACGGGCGG
CGCGAAGAAAGGCGTGCAAC

Downstream 100 bases:

>100_bases
ATGCGGGCCGACACAATTGTTGGCAGTCACGCTTTCGGAAATTGCCTACGATCTGGGTGCCGCGGACTCCGCATCCGCGC
GCCTTCCGGCCCGCGTCGTA

Product: putative periplasmic CHASE2 sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 819; Mature: 818

Protein sequence:

>819_residues
MAPNRTDLRSGQFDAAEREGAPGAMGFRRRTRLEWALLTAAVLVIALAASSFSWFERADLAVLDLAIVAQEHPARNDIVI
VAIDDESIGVIGRWPWRRTVLAALVDQIGADNPRAIGIDVILSEHDIRYPSDDAELARSVARSGNVVLPMVGESGSSGAR
LRGPMDGLLAQTGHINMIVDTDGVARQVYLREGDGEGPPVWHFAAAMAALGQHTPVTAAQFRNERAVRMDGAGWISQDRL
RIPFVGPPGSFARVSVLDVLSGEVSRGYFRDKSVLIGTVATGLGDVFPTPVSRDGRAMSGVEILANTLQALLDGTGIVTV
PKPVGWLGTILPVLLAALAALRFSPRNALLATVAIVAAVVGTSLCLPGSMHLWFAPSGAVLGCMMVYPLWSWRRQEAALR
FLSEELGRLAHEPGLLAAPATRIDHSLDGRMQAVYGMTSRLRDMRRFLSDGLESLPEATVICNLDGGILVANRRAVALAP
TMLQGIDGAYYANDLRYMRGSNTYGELGRPALPDLIEAMFTVAGPGLAYWDALCGALEGDAPVMSSSDSHGVELTTEDGR
RYLLHGGPLHGEAGRPAGVIVSLIDITAIRRAERQREQTLHFLSHDMRSPQASILALIDMQSRPDRALPQTELLGRIGEH
AHRTLALADDFIRIAQAESQSLTFAETDLTQIVLDATDEMWALAKARGTELRLDIDEQGPRLRVAPALLARAITNLVNNA
IKYSPCGTEVTVRLRRLGPYMAIEVSDQGPGISQDAQARLFRPFSRVHAHGADAPSGSGLGLVFVKTVAERHGGRVMVAS
EVGKGTMFSIWLPLRSRAS

Sequences:

>Translated_819_residues
MAPNRTDLRSGQFDAAEREGAPGAMGFRRRTRLEWALLTAAVLVIALAASSFSWFERADLAVLDLAIVAQEHPARNDIVI
VAIDDESIGVIGRWPWRRTVLAALVDQIGADNPRAIGIDVILSEHDIRYPSDDAELARSVARSGNVVLPMVGESGSSGAR
LRGPMDGLLAQTGHINMIVDTDGVARQVYLREGDGEGPPVWHFAAAMAALGQHTPVTAAQFRNERAVRMDGAGWISQDRL
RIPFVGPPGSFARVSVLDVLSGEVSRGYFRDKSVLIGTVATGLGDVFPTPVSRDGRAMSGVEILANTLQALLDGTGIVTV
PKPVGWLGTILPVLLAALAALRFSPRNALLATVAIVAAVVGTSLCLPGSMHLWFAPSGAVLGCMMVYPLWSWRRQEAALR
FLSEELGRLAHEPGLLAAPATRIDHSLDGRMQAVYGMTSRLRDMRRFLSDGLESLPEATVICNLDGGILVANRRAVALAP
TMLQGIDGAYYANDLRYMRGSNTYGELGRPALPDLIEAMFTVAGPGLAYWDALCGALEGDAPVMSSSDSHGVELTTEDGR
RYLLHGGPLHGEAGRPAGVIVSLIDITAIRRAERQREQTLHFLSHDMRSPQASILALIDMQSRPDRALPQTELLGRIGEH
AHRTLALADDFIRIAQAESQSLTFAETDLTQIVLDATDEMWALAKARGTELRLDIDEQGPRLRVAPALLARAITNLVNNA
IKYSPCGTEVTVRLRRLGPYMAIEVSDQGPGISQDAQARLFRPFSRVHAHGADAPSGSGLGLVFVKTVAERHGGRVMVAS
EVGKGTMFSIWLPLRSRAS
>Mature_818_residues
APNRTDLRSGQFDAAEREGAPGAMGFRRRTRLEWALLTAAVLVIALAASSFSWFERADLAVLDLAIVAQEHPARNDIVIV
AIDDESIGVIGRWPWRRTVLAALVDQIGADNPRAIGIDVILSEHDIRYPSDDAELARSVARSGNVVLPMVGESGSSGARL
RGPMDGLLAQTGHINMIVDTDGVARQVYLREGDGEGPPVWHFAAAMAALGQHTPVTAAQFRNERAVRMDGAGWISQDRLR
IPFVGPPGSFARVSVLDVLSGEVSRGYFRDKSVLIGTVATGLGDVFPTPVSRDGRAMSGVEILANTLQALLDGTGIVTVP
KPVGWLGTILPVLLAALAALRFSPRNALLATVAIVAAVVGTSLCLPGSMHLWFAPSGAVLGCMMVYPLWSWRRQEAALRF
LSEELGRLAHEPGLLAAPATRIDHSLDGRMQAVYGMTSRLRDMRRFLSDGLESLPEATVICNLDGGILVANRRAVALAPT
MLQGIDGAYYANDLRYMRGSNTYGELGRPALPDLIEAMFTVAGPGLAYWDALCGALEGDAPVMSSSDSHGVELTTEDGRR
YLLHGGPLHGEAGRPAGVIVSLIDITAIRRAERQREQTLHFLSHDMRSPQASILALIDMQSRPDRALPQTELLGRIGEHA
HRTLALADDFIRIAQAESQSLTFAETDLTQIVLDATDEMWALAKARGTELRLDIDEQGPRLRVAPALLARAITNLVNNAI
KYSPCGTEVTVRLRRLGPYMAIEVSDQGPGISQDAQARLFRPFSRVHAHGADAPSGSGLGLVFVKTVAERHGGRVMVASE
VGKGTMFSIWLPLRSRAS

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=375, Percent_Identity=25.8666666666667, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI48994928, Length=345, Percent_Identity=26.9565217391304, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1786783, Length=218, Percent_Identity=31.651376146789, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=27.8481012658228, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=26.7605633802817, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=8e-16,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=26.7543859649123, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=26.8398268398268, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=413, Percent_Identity=21.7917675544794, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=25.974025974026, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=22.9787234042553, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=26.2910798122066, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790861, Length=228, Percent_Identity=27.6315789473684, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=269, Percent_Identity=23.0483271375465, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=25.6756756756757, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88114; Mature: 87983

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPNRTDLRSGQFDAAEREGAPGAMGFRRRTRLEWALLTAAVLVIALAASSFSWFERADL
CCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCH
AVLDLAIVAQEHPARNDIVIVAIDDESIGVIGRWPWRRTVLAALVDQIGADNPRAIGIDV
HHHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEE
ILSEHDIRYPSDDAELARSVARSGNVVLPMVGESGSSGARLRGPMDGLLAQTGHINMIVD
EEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCHHHHHHCCCCEEEEEE
TDGVARQVYLREGDGEGPPVWHFAAAMAALGQHTPVTAAQFRNERAVRMDGAGWISQDRL
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCCCCCCCE
RIPFVGPPGSFARVSVLDVLSGEVSRGYFRDKSVLIGTVATGLGDVFPTPVSRDGRAMSG
EEEEECCCCCCHHHHHHHHHCCHHHCCEECCCCEEEEEHHHHCCCCCCCCCCCCCCCHHH
VEILANTLQALLDGTGIVTVPKPVGWLGTILPVLLAALAALRFSPRNALLATVAIVAAVV
HHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GTSLCLPGSMHLWFAPSGAVLGCMMVYPLWSWRRQEAALRFLSEELGRLAHEPGLLAAPA
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCH
TRIDHSLDGRMQAVYGMTSRLRDMRRFLSDGLESLPEATVICNLDGGILVANRRAVALAP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCEEEECH
TMLQGIDGAYYANDLRYMRGSNTYGELGRPALPDLIEAMFTVAGPGLAYWDALCGALEGD
HHHHCCCCCHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
APVMSSSDSHGVELTTEDGRRYLLHGGPLHGEAGRPAGVIVSLIDITAIRRAERQREQTL
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HFLSHDMRSPQASILALIDMQSRPDRALPQTELLGRIGEHAHRTLALADDFIRIAQAESQ
HHHHHHHCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLTFAETDLTQIVLDATDEMWALAKARGTELRLDIDEQGPRLRVAPALLARAITNLVNNA
CEEEEHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHCC
IKYSPCGTEVTVRLRRLGPYMAIEVSDQGPGISQDAQARLFRPFSRVHAHGADAPSGSGL
EEECCCCCHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
GLVFVKTVAERHGGRVMVASEVGKGTMFSIWLPLRSRAS
HHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
APNRTDLRSGQFDAAEREGAPGAMGFRRRTRLEWALLTAAVLVIALAASSFSWFERADL
CCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCH
AVLDLAIVAQEHPARNDIVIVAIDDESIGVIGRWPWRRTVLAALVDQIGADNPRAIGIDV
HHHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEE
ILSEHDIRYPSDDAELARSVARSGNVVLPMVGESGSSGARLRGPMDGLLAQTGHINMIVD
EEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCHHHHHHCCCCEEEEEE
TDGVARQVYLREGDGEGPPVWHFAAAMAALGQHTPVTAAQFRNERAVRMDGAGWISQDRL
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCCCCCCCE
RIPFVGPPGSFARVSVLDVLSGEVSRGYFRDKSVLIGTVATGLGDVFPTPVSRDGRAMSG
EEEEECCCCCCHHHHHHHHHCCHHHCCEECCCCEEEEEHHHHCCCCCCCCCCCCCCCHHH
VEILANTLQALLDGTGIVTVPKPVGWLGTILPVLLAALAALRFSPRNALLATVAIVAAVV
HHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GTSLCLPGSMHLWFAPSGAVLGCMMVYPLWSWRRQEAALRFLSEELGRLAHEPGLLAAPA
HHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCH
TRIDHSLDGRMQAVYGMTSRLRDMRRFLSDGLESLPEATVICNLDGGILVANRRAVALAP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCEEEECH
TMLQGIDGAYYANDLRYMRGSNTYGELGRPALPDLIEAMFTVAGPGLAYWDALCGALEGD
HHHHCCCCCHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
APVMSSSDSHGVELTTEDGRRYLLHGGPLHGEAGRPAGVIVSLIDITAIRRAERQREQTL
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HFLSHDMRSPQASILALIDMQSRPDRALPQTELLGRIGEHAHRTLALADDFIRIAQAESQ
HHHHHHHCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLTFAETDLTQIVLDATDEMWALAKARGTELRLDIDEQGPRLRVAPALLARAITNLVNNA
CEEEEHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHCC
IKYSPCGTEVTVRLRRLGPYMAIEVSDQGPGISQDAQARLFRPFSRVHAHGADAPSGSGL
EEECCCCCHHHHHEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
GLVFVKTVAERHGGRVMVASEVGKGTMFSIWLPLRSRAS
HHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]