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The map label for this gene is regX3 [H]

Identifier: 94313089

GI number: 94313089

Start: 744548

End: 745246

Strand: Direct

Name: regX3 [H]

Synonym: Rmet_4162

Alternate gene names: 94313089

Gene position: 744548-745246 (Clockwise)

Preceding gene: 94313088

Following gene: 94313090

Centisome position: 28.86

GC content: 64.23

Gene sequence:

>699_bases
ATGAGAATTGCCTCCGTGGAGGACGACACCAGCCAGGCCGAGCAGATTTGCCAGCTGCTGGATGAAGCGGGCTTTGAATG
CTCGAGCTTCGCGACCGGTTCCGCGTTCTTGCGAGCATTGCGGGACCAGGCGTTCGACCTGGTCGTCATGGACTGGCAAT
TGCCGGACGTCAGTGGTTACGAGCTCGTGAGCTGGGTCCGCCAGCATTCGGGACGCCTGCCACCGATCCTGTTCCTGACC
AGTCGCATCGAAGAATCCGATATCGTCGCGGGCCTGTCCGTGGGCGCCGACGATTACCTTGCCAAGCCGATCCGGCCGGG
CGAGTTCGTCGCGCGCGTGCGAGCGTTGCTGCGTCGCGCATATCCCAAGACCCTGCACGAAGACGATCTGATCCGGCAGG
GCGCCTATATCGTGGACGCGCGCCGGCGCGTTATCGCGCTGGACGGCCAGAACGTCGATCTGTCGCCGCGCGAGTTCGAC
CTGGCATTGTTCCTGTTCCGCAACATCGGCCGCCTGCTGGCGCGTGACGTGATTGAGCAGGCCGTCTGGGGGCGTGCGAT
GGATGCCGCCTCGCGCACGCTCGACACGCATATGTCGCGCCTGCGCATCAAGCTGGCCCTGCGCCCCGAAAACGGTGTGC
GGCTGGCTTCCGTCTATTCGCATGGCTATCGGTTCGAAGCCACGGCCGCTCATGAGTAG

Upstream 100 bases:

>100_bases
AGCGCAGAATCCCCTCTAACGTAGCCTCGACGGGCCGTGTTACCGTTCGGTAACATAACACCGCCGTGCCAGACACAGGC
CGTAGTTATCAGAGGGAAGT

Downstream 100 bases:

>100_bases
CCGTCCCACGTCGCACCGTGCCGCCGTGGGAGGTGCGCTGATTTCCCTGATTCTGTCTGGCAGTGCGCTGGCCGGCCCCG
CGGGCACGCAGGGCAAGGAT

Product: response regulator, OmpR-family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRIASVEDDTSQAEQICQLLDEAGFECSSFATGSAFLRALRDQAFDLVVMDWQLPDVSGYELVSWVRQHSGRLPPILFLT
SRIEESDIVAGLSVGADDYLAKPIRPGEFVARVRALLRRAYPKTLHEDDLIRQGAYIVDARRRVIALDGQNVDLSPREFD
LALFLFRNIGRLLARDVIEQAVWGRAMDAASRTLDTHMSRLRIKLALRPENGVRLASVYSHGYRFEATAAHE

Sequences:

>Translated_232_residues
MRIASVEDDTSQAEQICQLLDEAGFECSSFATGSAFLRALRDQAFDLVVMDWQLPDVSGYELVSWVRQHSGRLPPILFLT
SRIEESDIVAGLSVGADDYLAKPIRPGEFVARVRALLRRAYPKTLHEDDLIRQGAYIVDARRRVIALDGQNVDLSPREFD
LALFLFRNIGRLLARDVIEQAVWGRAMDAASRTLDTHMSRLRIKLALRPENGVRLASVYSHGYRFEATAAHE
>Mature_232_residues
MRIASVEDDTSQAEQICQLLDEAGFECSSFATGSAFLRALRDQAFDLVVMDWQLPDVSGYELVSWVRQHSGRLPPILFLT
SRIEESDIVAGLSVGADDYLAKPIRPGEFVARVRALLRRAYPKTLHEDDLIRQGAYIVDARRRVIALDGQNVDLSPREFD
LALFLFRNIGRLLARDVIEQAVWGRAMDAASRTLDTHMSRLRIKLALRPENGVRLASVYSHGYRFEATAAHE

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=34.9557522123894, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=37.8995433789954, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=206, Percent_Identity=34.9514563106796, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=33.0434782608696, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=32.8947368421053, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786784, Length=205, Percent_Identity=33.1707317073171, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=38.3333333333333, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=30.7017543859649, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=30.2631578947368, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787229, Length=211, Percent_Identity=29.8578199052133, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.3842794759825, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=30.1310043668122, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.0884955752212, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=28.755364806867, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26130; Mature: 26130

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIASVEDDTSQAEQICQLLDEAGFECSSFATGSAFLRALRDQAFDLVVMDWQLPDVSGY
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHH
ELVSWVRQHSGRLPPILFLTSRIEESDIVAGLSVGADDYLAKPIRPGEFVARVRALLRRA
HHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
YPKTLHEDDLIRQGAYIVDARRRVIALDGQNVDLSPREFDLALFLFRNIGRLLARDVIEQ
CCCCCCHHHHHHCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVWGRAMDAASRTLDTHMSRLRIKLALRPENGVRLASVYSHGYRFEATAAHE
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEHHCCEEEEECCCCC
>Mature Secondary Structure
MRIASVEDDTSQAEQICQLLDEAGFECSSFATGSAFLRALRDQAFDLVVMDWQLPDVSGY
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHH
ELVSWVRQHSGRLPPILFLTSRIEESDIVAGLSVGADDYLAKPIRPGEFVARVRALLRRA
HHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
YPKTLHEDDLIRQGAYIVDARRRVIALDGQNVDLSPREFDLALFLFRNIGRLLARDVIEQ
CCCCCCHHHHHHCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVWGRAMDAASRTLDTHMSRLRIKLALRPENGVRLASVYSHGYRFEATAAHE
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEHHCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA