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The map label for this gene is hmyB [H]

Identifier: 94313048

GI number: 94313048

Start: 691311

End: 692465

Strand: Direct

Name: hmyB [H]

Synonym: Rmet_4121

Alternate gene names: 94313048

Gene position: 691311-692465 (Clockwise)

Preceding gene: 94313047

Following gene: 94313050

Centisome position: 26.79

GC content: 65.97

Gene sequence:

>1155_bases
ATGCGTCCCCAATTCCTGCTTTCCTTTGCAGCCGCCGCCGTGATGATGCTGTCGCTGGCCGGCTGTTCCGATGACCCCGC
CCCGGCCGCCGAGGCGCCAAAGTTGCCACCTGGCATTGTCAAGCCCGAGGAGAACCTCAAGCGCACGCTCAAGGTGGCGC
CGGTTGCCGCGTCCCCATTCAGCGAGATGTTGCGCGTGGCGGGCCGTATCGACTTCGACGAGCAGCGCGTCTCGCGCATT
GGCGCCAGCGTGACTGGCCGCGTGACCGATCTCTATGCCGTGCTCGGCCAGGAAGTCAAGGCCGGCCAGGTGCTGGCCCG
CCTGCACAGTAGTGAACTGGGCGCTGCCCAGATGGCCTTCCTGAAGGCCGAAGCGCAGAACACGCTGCAGGCCCGCAATG
CTGAGCGCGCGCGGCAACTGTTCGCCGCCGACGTGATCGGCCGTGCCGAACTGCAGCGCCGCGAAAGCGAATACGCGATT
GCCGCGGCGGAGGCTCGTGCTTACCGCGATCAACTGCGCGTGCTCGGCATGTCCGCCGCGTCGATCGCCACGCTGGCGAA
GAGCGGCAGCATCGAGTCGTATTCGCCGGTGTTCTCGAGCATCAACGGCACGGTGGTCGAGCGCAATGTGGCGCAGGGCC
AGGTGGTGCAGCCGGCTGACGCGCTGTACACGGTGGCCGATCTGTCGCGCGTGTGGGTCGTCGCCGAGGTGCCCGAGCAG
CAGGCTGCGCAGGTGGCCGAAGGGCAGAGCGTCGATATCGAGGTGCCGTCACTGGCCAACAGCAATGGTCGCATCACGGG
CAAGCTGATCTACGTGGGTCGGACCGTGAATCCGCAGTCGCGCACGGTGCTGGTTCGTACCGAACTCCAGAACAAGGATG
GCCGTCTCAAGCCCGCCATGCTTGCCACCATGCTGATCGCCGCCAAGCCGGTGGAACTGCTGGTGGTGCCGGGTTCAGCC
GTGGTCCGTGAAGGCAACGATGAACAGGTCTATGTGGAAGTTGGCGACGGCCAGTACCGCCTGACCAAGGTGAAGCTGGG
CCCGGAGAGCGACGGCATGCGTGTGGTCCAGAGCGGCATCAAGCCTGGCGACCGCGTGGTCGTGGAAGGCGCGTTCCATC
TGGACAACGAGCGCAAGCAGCAGGAGCAGGGGTAA

Upstream 100 bases:

>100_bases
AAGTCGCCGCCATCCAGATTGACAAGCTCATGTCGGCCTCGCCGGGCGTCAATACCGCCCCTGCGTCGTCCATGCCCGAC
CTCCCGAATCTGAACTGATC

Downstream 100 bases:

>100_bases
CCGGCCATGATGACATCGCTTGTTGAAGCCGCGATCAAGCAGCGGCTGGTGGTGGGCGGTTTCAAGTCCAAGTGCAACAA
AAACTCAATGCACTAAATCC

Product: heavy metal cation tricomponent efflux, membrane fusion protein HmyB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRPQFLLSFAAAAVMMLSLAGCSDDPAPAAEAPKLPPGIVKPEENLKRTLKVAPVAASPFSEMLRVAGRIDFDEQRVSRI
GASVTGRVTDLYAVLGQEVKAGQVLARLHSSELGAAQMAFLKAEAQNTLQARNAERARQLFAADVIGRAELQRRESEYAI
AAAEARAYRDQLRVLGMSAASIATLAKSGSIESYSPVFSSINGTVVERNVAQGQVVQPADALYTVADLSRVWVVAEVPEQ
QAAQVAEGQSVDIEVPSLANSNGRITGKLIYVGRTVNPQSRTVLVRTELQNKDGRLKPAMLATMLIAAKPVELLVVPGSA
VVREGNDEQVYVEVGDGQYRLTKVKLGPESDGMRVVQSGIKPGDRVVVEGAFHLDNERKQQEQG

Sequences:

>Translated_384_residues
MRPQFLLSFAAAAVMMLSLAGCSDDPAPAAEAPKLPPGIVKPEENLKRTLKVAPVAASPFSEMLRVAGRIDFDEQRVSRI
GASVTGRVTDLYAVLGQEVKAGQVLARLHSSELGAAQMAFLKAEAQNTLQARNAERARQLFAADVIGRAELQRRESEYAI
AAAEARAYRDQLRVLGMSAASIATLAKSGSIESYSPVFSSINGTVVERNVAQGQVVQPADALYTVADLSRVWVVAEVPEQ
QAAQVAEGQSVDIEVPSLANSNGRITGKLIYVGRTVNPQSRTVLVRTELQNKDGRLKPAMLATMLIAAKPVELLVVPGSA
VVREGNDEQVYVEVGDGQYRLTKVKLGPESDGMRVVQSGIKPGDRVVVEGAFHLDNERKQQEQG
>Mature_384_residues
MRPQFLLSFAAAAVMMLSLAGCSDDPAPAAEAPKLPPGIVKPEENLKRTLKVAPVAASPFSEMLRVAGRIDFDEQRVSRI
GASVTGRVTDLYAVLGQEVKAGQVLARLHSSELGAAQMAFLKAEAQNTLQARNAERARQLFAADVIGRAELQRRESEYAI
AAAEARAYRDQLRVLGMSAASIATLAKSGSIESYSPVFSSINGTVVERNVAQGQVVQPADALYTVADLSRVWVVAEVPEQ
QAAQVAEGQSVDIEVPSLANSNGRITGKLIYVGRTVNPQSRTVLVRTELQNKDGRLKPAMLATMLIAAKPVELLVVPGSA
VVREGNDEQVYVEVGDGQYRLTKVKLGPESDGMRVVQSGIKPGDRVVVEGAFHLDNERKQQEQG

Specific function: Component of the sil cation efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=229, Percent_Identity=25.3275109170306, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082036, Length=306, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41181; Mature: 41181

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPQFLLSFAAAAVMMLSLAGCSDDPAPAAEAPKLPPGIVKPEENLKRTLKVAPVAASPF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCH
SEMLRVAGRIDFDEQRVSRIGASVTGRVTDLYAVLGQEVKAGQVLARLHSSELGAAQMAF
HHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
LKAEAQNTLQARNAERARQLFAADVIGRAELQRRESEYAIAAAEARAYRDQLRVLGMSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEHHHHHHHHHHHHHHCCCHH
SIATLAKSGSIESYSPVFSSINGTVVERNVAQGQVVQPADALYTVADLSRVWVVAEVPEQ
HHHHHHHCCCCCCCCHHHHCCCCEEEECCCCCCCEECCHHHHHHHHHHHEEEEEEECCHH
QAAQVAEGQSVDIEVPSLANSNGRITGKLIYVGRTVNPQSRTVLVRTELQNKDGRLKPAM
HHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHH
LATMLIAAKPVELLVVPGSAVVREGNDEQVYVEVGDGQYRLTKVKLGPESDGMRVVQSGI
HHHHHHHCCCEEEEEECCHHEEECCCCCEEEEEECCCEEEEEEEEECCCCCCHHHHHHCC
KPGDRVVVEGAFHLDNERKQQEQG
CCCCEEEEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MRPQFLLSFAAAAVMMLSLAGCSDDPAPAAEAPKLPPGIVKPEENLKRTLKVAPVAASPF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCH
SEMLRVAGRIDFDEQRVSRIGASVTGRVTDLYAVLGQEVKAGQVLARLHSSELGAAQMAF
HHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
LKAEAQNTLQARNAERARQLFAADVIGRAELQRRESEYAIAAAEARAYRDQLRVLGMSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEHHHHHHHHHHHHHHCCCHH
SIATLAKSGSIESYSPVFSSINGTVVERNVAQGQVVQPADALYTVADLSRVWVVAEVPEQ
HHHHHHHCCCCCCCCHHHHCCCCEEEECCCCCCCEECCHHHHHHHHHHHEEEEEEECCHH
QAAQVAEGQSVDIEVPSLANSNGRITGKLIYVGRTVNPQSRTVLVRTELQNKDGRLKPAM
HHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHH
LATMLIAAKPVELLVVPGSAVVREGNDEQVYVEVGDGQYRLTKVKLGPESDGMRVVQSGI
HHHHHHHCCCEEEEEECCHHEEECCCCCEEEEEECCCEEEEEEEEECCCCCCHHHHHHCC
KPGDRVVVEGAFHLDNERKQQEQG
CCCCEEEEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]