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The map label for this gene is acxR [H]

Identifier: 94313031

GI number: 94313031

Start: 672617

End: 674602

Strand: Reverse

Name: acxR [H]

Synonym: Rmet_4104

Alternate gene names: 94313031

Gene position: 674602-672617 (Counterclockwise)

Preceding gene: 94313035

Following gene: 291481513

Centisome position: 26.15

GC content: 65.06

Gene sequence:

>1986_bases
ATGCCGTTCACCCACTACGGCACTCTGGTCCCCCGCATCAGCGACGAACCTGTCGTGGCCTCGGCCTGGGAACGCTTCCT
GCGGGACCATCCCCATCATCCACATGAAGGGGACGGTGTGCGCAGAGTTGTCCTCGCTTCCTGGCAGCGGTGTCGTTCCG
AAGCTGTCGACCCGACCCTGCATTCGGCGCCGGGCGCCGCCGACGATCGCCTTCGACAACTGCGCACGCAAAACCGCGAC
CTCTGCGACGCAGCGGGTCCGGCGCTCGAAGGCCTGCGCGACATCTTGCGCGAATGCGGCACGCTGATCATGCTCAGCGA
CACCGACGGCACCATCCTTCAGCTCAATGGCTCGACCCGCGTGCGCAGCGTCGGCGAGGAAGTCAACCTTGCCATGGGCG
GATGCTGGAGCGAGGAAGTGATCGGCACCAATGCCATCGGCACCGCAATCGCCACCGTCGCGCCGGTGCAGATCCATGCC
AGCGAGCATTTCTGCTGGGACGTCAAACGCTGGACCTGCGCCGCCGCGCCGATACTCGATCCGTTCGGACGTCACCTGCT
TGGCGTCGTTGATGTATCGGGGGTGAAGGAGTCATTCCACGGGCACACCCTCGGTCTGGTGGTGGCGGCGGCCCGGCAGA
TCGAGAGCGAACTGGCGCGGCGCGACATGGCGATGCACGAGCGCCTGCTAGCCCGCTCCATCGATGATTTCGTGCGCTAT
GCCAGCGACTGCGTGGTCCTTGCCGATTTCCGCGGCCGTGTCGTTCGTATCAACGGCCGCGCGCAGGCGGCGCGGGATGC
CCATGGCGTATGTTTCGCACTGGAGACCGGCAACGCGATACCAGGGCTCGATCTCACACTGCCGGAAGTCGATCAAATAC
ATCAGCGCCCGGGCTGGCTGCGGCCCGAATGGCTTCACACGGTCAAGGATCGCGAAGGACTGCTCGGCACGATGCTCGTG
ATTCCACTCGCGGCACGCCCGGGCCGGACCAGCATTTCACTCCCCGCCACCCCGACTGCGGTGACAACGGATGACGCGTT
CACCGAGATCATCGGCGAGAGCGAAATTCTCGCCGCCACCAAGGCACGCGCCCGCCGTATCGCGTCGCTCGATCTGCCCG
TGCTGCTGGTCGGTGAGACCGGCGCGGGCAAGGAGCTGTTCGCGCGCGCGTTGCATCGGTCTGGCAAGCGGCCCGACGGT
CCATTCGTTGCCGTGAATTGCGGCGCCCTGACGCGCGAATTGCTGGCCAGCGAGCTCTTTGGCTACGCGGAAGGCGCCTT
CACGGGGGCGCGTCGCGGCGGCCATCCGGGAAAATTCGAACAGGCCGCAGGCGGCACGCTGTTCCTCGACGAGATCGGCG
AGATGCCGCTCGACATGCAGCCGCATCTATTGCGTGTGCTGCAGGATGGCGTGGTGGTTCGTCTGGGGGATACGAGGGAG
CGGCAGGTATCGGTCCGACTTGTCGCCGCGACCAACCGCGATCTGCAGAAGGAGATTGCCGCCGGGCGCTTTCGCGAGGA
TCTGTACCACCGTCTCTGCGCGGTCAGTCTGCAGCTTCCGGCCCTACGCGACCGGCCTGGCGATATCGAGTCCATCGTCG
ATCACCTCAACCACAAGCTCGCGCGCAAGTACGGGTGCGCGCCGAAGCAGATCGAACCGTCGGTCTATCAGACACTGGTG
CGCTATCGCTGGCCCGGGAATATTCGTGAACTGCAGAACGTATTCGAGGTGATGTTCGCGCTCGGCGAGAACAATGGCAT
CGATGTGTCGATGTTGTCCTCCCTAGTCGAATCCGGACCGGCCGGAGACGCGATGGCACCGGCCCCGATGCCGATGTCGG
CAGCGTCTGGCCGCCTCGACGATCTGGAGCGGCAGGCGATACGCGCCGCCATCAACGATGCGCGCGGCAACCTTTCAAAG
GCCGCCAGAACGCTGGGGATTTCAAGAAGCACGCTCTACGTCAAGCTTGCGGCCCTCCGGACCTAA

Upstream 100 bases:

>100_bases
CCCCTGCTGCACAGCACAAACCCTTGATTGCAAAGAGAATTGTTGACTTGCGAAAAGCGTGGGGCTACGGTTGCCGGAAT
CAACTGAGAGTGATCGTCCC

Downstream 100 bases:

>100_bases
GAGGCGCTATCAAAATGATTCTGGCGTCGTTGCGCGGCCTTGGCCGGTCTACTTGTACTGTCTGCGGCCGCGCCCTTGCA
GGGCGCGCATGTGCTCGCAG

Product: sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MPFTHYGTLVPRISDEPVVASAWERFLRDHPHHPHEGDGVRRVVLASWQRCRSEAVDPTLHSAPGAADDRLRQLRTQNRD
LCDAAGPALEGLRDILRECGTLIMLSDTDGTILQLNGSTRVRSVGEEVNLAMGGCWSEEVIGTNAIGTAIATVAPVQIHA
SEHFCWDVKRWTCAAAPILDPFGRHLLGVVDVSGVKESFHGHTLGLVVAAARQIESELARRDMAMHERLLARSIDDFVRY
ASDCVVLADFRGRVVRINGRAQAARDAHGVCFALETGNAIPGLDLTLPEVDQIHQRPGWLRPEWLHTVKDREGLLGTMLV
IPLAARPGRTSISLPATPTAVTTDDAFTEIIGESEILAATKARARRIASLDLPVLLVGETGAGKELFARALHRSGKRPDG
PFVAVNCGALTRELLASELFGYAEGAFTGARRGGHPGKFEQAAGGTLFLDEIGEMPLDMQPHLLRVLQDGVVVRLGDTRE
RQVSVRLVAATNRDLQKEIAAGRFREDLYHRLCAVSLQLPALRDRPGDIESIVDHLNHKLARKYGCAPKQIEPSVYQTLV
RYRWPGNIRELQNVFEVMFALGENNGIDVSMLSSLVESGPAGDAMAPAPMPMSAASGRLDDLERQAIRAAINDARGNLSK
AARTLGISRSTLYVKLAALRT

Sequences:

>Translated_661_residues
MPFTHYGTLVPRISDEPVVASAWERFLRDHPHHPHEGDGVRRVVLASWQRCRSEAVDPTLHSAPGAADDRLRQLRTQNRD
LCDAAGPALEGLRDILRECGTLIMLSDTDGTILQLNGSTRVRSVGEEVNLAMGGCWSEEVIGTNAIGTAIATVAPVQIHA
SEHFCWDVKRWTCAAAPILDPFGRHLLGVVDVSGVKESFHGHTLGLVVAAARQIESELARRDMAMHERLLARSIDDFVRY
ASDCVVLADFRGRVVRINGRAQAARDAHGVCFALETGNAIPGLDLTLPEVDQIHQRPGWLRPEWLHTVKDREGLLGTMLV
IPLAARPGRTSISLPATPTAVTTDDAFTEIIGESEILAATKARARRIASLDLPVLLVGETGAGKELFARALHRSGKRPDG
PFVAVNCGALTRELLASELFGYAEGAFTGARRGGHPGKFEQAAGGTLFLDEIGEMPLDMQPHLLRVLQDGVVVRLGDTRE
RQVSVRLVAATNRDLQKEIAAGRFREDLYHRLCAVSLQLPALRDRPGDIESIVDHLNHKLARKYGCAPKQIEPSVYQTLV
RYRWPGNIRELQNVFEVMFALGENNGIDVSMLSSLVESGPAGDAMAPAPMPMSAASGRLDDLERQAIRAAINDARGNLSK
AARTLGISRSTLYVKLAALRT
>Mature_660_residues
PFTHYGTLVPRISDEPVVASAWERFLRDHPHHPHEGDGVRRVVLASWQRCRSEAVDPTLHSAPGAADDRLRQLRTQNRDL
CDAAGPALEGLRDILRECGTLIMLSDTDGTILQLNGSTRVRSVGEEVNLAMGGCWSEEVIGTNAIGTAIATVAPVQIHAS
EHFCWDVKRWTCAAAPILDPFGRHLLGVVDVSGVKESFHGHTLGLVVAAARQIESELARRDMAMHERLLARSIDDFVRYA
SDCVVLADFRGRVVRINGRAQAARDAHGVCFALETGNAIPGLDLTLPEVDQIHQRPGWLRPEWLHTVKDREGLLGTMLVI
PLAARPGRTSISLPATPTAVTTDDAFTEIIGESEILAATKARARRIASLDLPVLLVGETGAGKELFARALHRSGKRPDGP
FVAVNCGALTRELLASELFGYAEGAFTGARRGGHPGKFEQAAGGTLFLDEIGEMPLDMQPHLLRVLQDGVVVRLGDTRER
QVSVRLVAATNRDLQKEIAAGRFREDLYHRLCAVSLQLPALRDRPGDIESIVDHLNHKLARKYGCAPKQIEPSVYQTLVR
YRWPGNIRELQNVFEVMFALGENNGIDVSMLSSLVESGPAGDAMAPAPMPMSAASGRLDDLERQAIRAAINDARGNLSKA
ARTLGISRSTLYVKLAALRT

Specific function: Unknown

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=360, Percent_Identity=37.7777777777778, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI87082117, Length=321, Percent_Identity=41.1214953271028, Blast_Score=226, Evalue=5e-60,
Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=41.8831168831169, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1788905, Length=320, Percent_Identity=40.625, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1790299, Length=340, Percent_Identity=38.2352941176471, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789087, Length=332, Percent_Identity=40.0602409638554, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI1788550, Length=293, Percent_Identity=41.9795221843003, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786524, Length=339, Percent_Identity=38.9380530973451, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI87081872, Length=308, Percent_Identity=38.6363636363636, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI87082152, Length=311, Percent_Identity=38.2636655948553, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1787583, Length=360, Percent_Identity=33.8888888888889, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI87081858, Length=644, Percent_Identity=27.3291925465839, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789828, Length=332, Percent_Identity=31.9277108433735, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72025; Mature: 71894

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFTHYGTLVPRISDEPVVASAWERFLRDHPHHPHEGDGVRRVVLASWQRCRSEAVDPTL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
HSAPGAADDRLRQLRTQNRDLCDAAGPALEGLRDILRECGTLIMLSDTDGTILQLNGSTR
HCCCCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCHH
VRSVGEEVNLAMGGCWSEEVIGTNAIGTAIATVAPVQIHASEHFCWDVKRWTCAAAPILD
HHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCEEEECCCCEEEECCHHHHHCCHHHC
PFGRHLLGVVDVSGVKESFHGHTLGLVVAAARQIESELARRDMAMHERLLARSIDDFVRY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDCVVLADFRGRVVRINGRAQAARDAHGVCFALETGNAIPGLDLTLPEVDQIHQRPGWL
HCCEEEEEECCCEEEEECCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCCC
RPEWLHTVKDREGLLGTMLVIPLAARPGRTSISLPATPTAVTTDDAFTEIIGESEILAAT
CHHHHHHHHHHCCHHHHHHHHEECCCCCCCEEECCCCCCEEECCHHHHHHHCCCHHHHHH
KARARRIASLDLPVLLVGETGAGKELFARALHRSGKRPDGPFVAVNCGALTRELLASELF
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHH
GYAEGAFTGARRGGHPGKFEQAAGGTLFLDEIGEMPLDMQPHLLRVLQDGVVVRLGDTRE
HHHCCCCCCCCCCCCCCCCHHCCCCEEEHHHHCCCCCCCCHHHHHHHHCCEEEEECCCCC
RQVSVRLVAATNRDLQKEIAAGRFREDLYHRLCAVSLQLPALRDRPGDIESIVDHLNHKL
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ARKYGCAPKQIEPSVYQTLVRYRWPGNIRELQNVFEVMFALGENNGIDVSMLSSLVESGP
HHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
AGDAMAPAPMPMSAASGRLDDLERQAIRAAINDARGNLSKAARTLGISRSTLYVKLAALR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECC
T
C
>Mature Secondary Structure 
PFTHYGTLVPRISDEPVVASAWERFLRDHPHHPHEGDGVRRVVLASWQRCRSEAVDPTL
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
HSAPGAADDRLRQLRTQNRDLCDAAGPALEGLRDILRECGTLIMLSDTDGTILQLNGSTR
HCCCCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCHH
VRSVGEEVNLAMGGCWSEEVIGTNAIGTAIATVAPVQIHASEHFCWDVKRWTCAAAPILD
HHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCEEEECCCCEEEECCHHHHHCCHHHC
PFGRHLLGVVDVSGVKESFHGHTLGLVVAAARQIESELARRDMAMHERLLARSIDDFVRY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDCVVLADFRGRVVRINGRAQAARDAHGVCFALETGNAIPGLDLTLPEVDQIHQRPGWL
HCCEEEEEECCCEEEEECCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCCC
RPEWLHTVKDREGLLGTMLVIPLAARPGRTSISLPATPTAVTTDDAFTEIIGESEILAAT
CHHHHHHHHHHCCHHHHHHHHEECCCCCCCEEECCCCCCEEECCHHHHHHHCCCHHHHHH
KARARRIASLDLPVLLVGETGAGKELFARALHRSGKRPDGPFVAVNCGALTRELLASELF
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHH
GYAEGAFTGARRGGHPGKFEQAAGGTLFLDEIGEMPLDMQPHLLRVLQDGVVVRLGDTRE
HHHCCCCCCCCCCCCCCCCHHCCCCEEEHHHHCCCCCCCCHHHHHHHHCCEEEEECCCCC
RQVSVRLVAATNRDLQKEIAAGRFREDLYHRLCAVSLQLPALRDRPGDIESIVDHLNHKL
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ARKYGCAPKQIEPSVYQTLVRYRWPGNIRELQNVFEVMFALGENNGIDVSMLSSLVESGP
HHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
AGDAMAPAPMPMSAASGRLDDLERQAIRAAINDARGNLSKAARTLGISRSTLYVKLAALR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA