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The map label for this gene is oxlT [H]

Identifier: 94313006

GI number: 94313006

Start: 646989

End: 648416

Strand: Reverse

Name: oxlT [H]

Synonym: Rmet_4078

Alternate gene names: 94313006

Gene position: 648416-646989 (Counterclockwise)

Preceding gene: 291481509

Following gene: 291481507

Centisome position: 25.13

GC content: 63.94

Gene sequence:

>1428_bases
ATGAGCAGTGTGATGAATGAAGGCAGCAGCCCGGCCTATGGCCCGGCCCCGTTCTTTTCCAAGGAAGCGACCTACGCCAA
GCCGGGATTTTCCCGCTGGATGGTCCCGCCCGCCGCGCTGGCGGTTCACCTTTGCATCGGCCAGGCCTATGCATTCTCGG
TATTCAACGTACCGCTATCGAGGGTAATCGGCATTACCGAGTCAGCGCCCGATGACTGGAAACTGACCACGCTTGGCTGG
ATTTTCTCGCTGGCGATCTTCTTCCTTGGCATTTCCGCTGCATTCGCCGGCAAATGGCTCGAGCGCGTGGGTCCACGACT
GACGATGTTCACCGCCGCCTGCTGCTTTGGCAGCGGGTTCCTGGTCTCCGCGCTGGGTATCTACACGCACCAGATCGCCC
TGCTCTATCTCGGTTACGGCGTGCTGGGCGGCATCGGACTGGGCCTGGGCTATGTATCGCCCGTGTCCACGCTGATTCGC
TGGTTCCCGGACCGTCGCGGCATGGCCACCGGCATGGCGATCATGGGCTTCGGCGGCGGCGCGATGATCGCCGCACCGCT
GTCCGTGGCGCTGATGAACACCTTCAAGAGCGCTACGTCGGTCGGTGTGGCCCAGACTTTCGTGGTCATGGGCATCGGCT
ACTTCGTGTCGATGCTGATCGGCTCGCTGGCCATCCGCGTGCCCGCCCCGGGCTGGAAGCCGGCCGGCTGGACCCCGCCC
ACCACCGCCAGCAAGATGATCACGCGTAACCACGTGCACATCGACCAGGCTCTGAAGACGTCTCAGTTCTACCTGCTGTG
GCTGGTGCTGTTCCTGAACGTGACGGCCGGCATCGGCGTGCTGGGTCAGGCGTCGCTGATGATTCAGGAGAGCTTCAAGG
GCAGCGTGACCGCCGCCGCCGCAGCCGGCTTCGTGGGCCTGCTGTCTCTGTTCAATATGGGCGGCCGCTTTTTCTGGGCT
TCGTCCTCTGACTGGATCGGCCGCAAGAACACCTACTTCGTATTCTTCGCCCTGGGCGCTGTCCTGTACTGGCTGGTGCC
ACAGCTTGGCGCAAGCGGCAACATCGCGCTGTTCGTGCTGGCCTACTGCGTGATCATGTCGATGTACGGTGGCGGCTTCG
CCACGATCCCGGCTTATCTGGCCGACATGTTCGGCACCGCCTTCGTGGGCGGCATCCACGGTCGCCTGCTGACGGCCTGG
GCCGCTGCGGGTATTGCCGGCCCGGTGCTCGTGAACTACATCCGCGAGTACCAGGTAGCGCACGGCGTGACCGGCGCCGA
CGCGTACACGATGACGCTGCACATCATGGCGGCCCTGCTCGTGGTCGGCTTCATCTGCAATCTGCTGGTGGCGCGCGTCA
GCGACAGGCACCACATGAGCGAAGCCGATGTATCCAGCCTTGCCGGCAATGCCAGCGCCGCCCACTGA

Upstream 100 bases:

>100_bases
CCGCGGCGTGACGGGTCAACCGGCTGGGCCACCCAGACCCGCCGGCGCGCCATGCTGCAAGCGGAACGGTTGCCCAGGAC
CCTCGTCTGGAGAACGCTCG

Downstream 100 bases:

>100_bases
CCGCCCGACGAAGAGATGCACATGGACAACTCACAAGTGAAAGCCCAACCCACCAGCAAAGGCCTGCTGGCCATCTTCTG
GCTGTATGTGCTGGTCCCGC

Product: major facilitator superfamily oxalate/formate antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSSVMNEGSSPAYGPAPFFSKEATYAKPGFSRWMVPPAALAVHLCIGQAYAFSVFNVPLSRVIGITESAPDDWKLTTLGW
IFSLAIFFLGISAAFAGKWLERVGPRLTMFTAACCFGSGFLVSALGIYTHQIALLYLGYGVLGGIGLGLGYVSPVSTLIR
WFPDRRGMATGMAIMGFGGGAMIAAPLSVALMNTFKSATSVGVAQTFVVMGIGYFVSMLIGSLAIRVPAPGWKPAGWTPP
TTASKMITRNHVHIDQALKTSQFYLLWLVLFLNVTAGIGVLGQASLMIQESFKGSVTAAAAAGFVGLLSLFNMGGRFFWA
SSSDWIGRKNTYFVFFALGAVLYWLVPQLGASGNIALFVLAYCVIMSMYGGGFATIPAYLADMFGTAFVGGIHGRLLTAW
AAAGIAGPVLVNYIREYQVAHGVTGADAYTMTLHIMAALLVVGFICNLLVARVSDRHHMSEADVSSLAGNASAAH

Sequences:

>Translated_475_residues
MSSVMNEGSSPAYGPAPFFSKEATYAKPGFSRWMVPPAALAVHLCIGQAYAFSVFNVPLSRVIGITESAPDDWKLTTLGW
IFSLAIFFLGISAAFAGKWLERVGPRLTMFTAACCFGSGFLVSALGIYTHQIALLYLGYGVLGGIGLGLGYVSPVSTLIR
WFPDRRGMATGMAIMGFGGGAMIAAPLSVALMNTFKSATSVGVAQTFVVMGIGYFVSMLIGSLAIRVPAPGWKPAGWTPP
TTASKMITRNHVHIDQALKTSQFYLLWLVLFLNVTAGIGVLGQASLMIQESFKGSVTAAAAAGFVGLLSLFNMGGRFFWA
SSSDWIGRKNTYFVFFALGAVLYWLVPQLGASGNIALFVLAYCVIMSMYGGGFATIPAYLADMFGTAFVGGIHGRLLTAW
AAAGIAGPVLVNYIREYQVAHGVTGADAYTMTLHIMAALLVVGFICNLLVARVSDRHHMSEADVSSLAGNASAAH
>Mature_474_residues
SSVMNEGSSPAYGPAPFFSKEATYAKPGFSRWMVPPAALAVHLCIGQAYAFSVFNVPLSRVIGITESAPDDWKLTTLGWI
FSLAIFFLGISAAFAGKWLERVGPRLTMFTAACCFGSGFLVSALGIYTHQIALLYLGYGVLGGIGLGLGYVSPVSTLIRW
FPDRRGMATGMAIMGFGGGAMIAAPLSVALMNTFKSATSVGVAQTFVVMGIGYFVSMLIGSLAIRVPAPGWKPAGWTPPT
TASKMITRNHVHIDQALKTSQFYLLWLVLFLNVTAGIGVLGQASLMIQESFKGSVTAAAAAGFVGLLSLFNMGGRFFWAS
SSDWIGRKNTYFVFFALGAVLYWLVPQLGASGNIALFVLAYCVIMSMYGGGFATIPAYLADMFGTAFVGGIHGRLLTAWA
AAGIAGPVLVNYIREYQVAHGVTGADAYTMTLHIMAALLVVGFICNLLVARVSDRHHMSEADVSSLAGNASAAH

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789969, Length=382, Percent_Identity=25.130890052356, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI115532490, Length=357, Percent_Identity=26.6106442577031, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115532488, Length=357, Percent_Identity=26.6106442577031, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50249; Mature: 50118

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVMNEGSSPAYGPAPFFSKEATYAKPGFSRWMVPPAALAVHLCIGQAYAFSVFNVPLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
RVIGITESAPDDWKLTTLGWIFSLAIFFLGISAAFAGKWLERVGPRLTMFTAACCFGSGF
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
LVSALGIYTHQIALLYLGYGVLGGIGLGLGYVSPVSTLIRWFPDRRGMATGMAIMGFGGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEECCCC
AMIAAPLSVALMNTFKSATSVGVAQTFVVMGIGYFVSMLIGSLAIRVPAPGWKPAGWTPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
TTASKMITRNHVHIDQALKTSQFYLLWLVLFLNVTAGIGVLGQASLMIQESFKGSVTAAA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
AAGFVGLLSLFNMGGRFFWASSSDWIGRKNTYFVFFALGAVLYWLVPQLGASGNIALFVL
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHH
AYCVIMSMYGGGFATIPAYLADMFGTAFVGGIHGRLLTAWAAAGIAGPVLVNYIREYQVA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
HGVTGADAYTMTLHIMAALLVVGFICNLLVARVSDRHHMSEADVSSLAGNASAAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSVMNEGSSPAYGPAPFFSKEATYAKPGFSRWMVPPAALAVHLCIGQAYAFSVFNVPLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
RVIGITESAPDDWKLTTLGWIFSLAIFFLGISAAFAGKWLERVGPRLTMFTAACCFGSGF
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
LVSALGIYTHQIALLYLGYGVLGGIGLGLGYVSPVSTLIRWFPDRRGMATGMAIMGFGGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEECCCC
AMIAAPLSVALMNTFKSATSVGVAQTFVVMGIGYFVSMLIGSLAIRVPAPGWKPAGWTPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
TTASKMITRNHVHIDQALKTSQFYLLWLVLFLNVTAGIGVLGQASLMIQESFKGSVTAAA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
AAGFVGLLSLFNMGGRFFWASSSDWIGRKNTYFVFFALGAVLYWLVPQLGASGNIALFVL
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHH
AYCVIMSMYGGGFATIPAYLADMFGTAFVGGIHGRLLTAWAAAGIAGPVLVNYIREYQVA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
HGVTGADAYTMTLHIMAALLVVGFICNLLVARVSDRHHMSEADVSSLAGNASAAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]