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The map label for this gene is ccmE [H]

Identifier: 94312985

GI number: 94312985

Start: 624068

End: 624517

Strand: Reverse

Name: ccmE [H]

Synonym: Rmet_4057

Alternate gene names: 94312985

Gene position: 624517-624068 (Counterclockwise)

Preceding gene: 291481506

Following gene: 94312984

Centisome position: 24.21

GC content: 65.11

Gene sequence:

>450_bases
ATGACGCGCAGGCAACGTCGCCTCGGTCTGCTGCTGGCCGCGCTGCTGTGCGGCGGCACGGCACTGGCATTCGTACTGAA
TGCGTTTCGCTCCAATCTCGTCTTCTTCTTCAGCCCGACCCAGGTGGCCGCGCACGAAGCGCCGGCGTCACGCAATTTTC
GTCTCGGCGGCCTGGTCGCCCCCGGCTCGCTGAAGCGCGATCCAGAAAACCTGACGATCCGCTTCGTCGTGACCGATACA
CGGCACGACATACCCGTGGTCTACCGTGGCCTGCTACCGGACCTGTTCCGCGAGGGCAAGGGCGTGGTGGCACGCGGGGC
ACTCGATCGCGACGGCACGTTCGTCGCCAGCGAAATCCTGGCCAAGCATGACGAGAACTACATGCCGCCCGAAGCCGCCG
ACGCGCTCAAACGCGCCGCATCGGACAACCCCACGGAAAAAACGCGATGA

Upstream 100 bases:

>100_bases
ATATCGCAAGCGCCTTCGGCATGACCTTCGTGCTAATCGCCGCGGAACTGATCCTGCTCTGCGCGCGGCGCCGCAACAGC
CTGCGGGCACGGTCGCGCCG

Downstream 100 bases:

>100_bases
ATCCGGAACTGGGCCACTTCGCACTGATCCTGGCCATGCTCGTGGCGCTGGTGCTGGCAACGCTGCCGATGGTGGGCGCG
GCGCGCGGCAATGTTGCCTG

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTRRQRRLGLLLAALLCGGTALAFVLNAFRSNLVFFFSPTQVAAHEAPASRNFRLGGLVAPGSLKRDPENLTIRFVVTDT
RHDIPVVYRGLLPDLFREGKGVVARGALDRDGTFVASEILAKHDENYMPPEAADALKRAASDNPTEKTR

Sequences:

>Translated_149_residues
MTRRQRRLGLLLAALLCGGTALAFVLNAFRSNLVFFFSPTQVAAHEAPASRNFRLGGLVAPGSLKRDPENLTIRFVVTDT
RHDIPVVYRGLLPDLFREGKGVVARGALDRDGTFVASEILAKHDENYMPPEAADALKRAASDNPTEKTR
>Mature_148_residues
TRRQRRLGLLLAALLCGGTALAFVLNAFRSNLVFFFSPTQVAAHEAPASRNFRLGGLVAPGSLKRDPENLTIRFVVTDTR
HDIPVVYRGLLPDLFREGKGVVARGALDRDGTFVASEILAKHDENYMPPEAADALKRAASDNPTEKTR

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=141, Percent_Identity=41.1347517730496, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 16331; Mature: 16200

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRQRRLGLLLAALLCGGTALAFVLNAFRSNLVFFFSPTQVAAHEAPASRNFRLGGLVA
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCCEEECCEEC
PGSLKRDPENLTIRFVVTDTRHDIPVVYRGLLPDLFREGKGVVARGALDRDGTFVASEIL
CCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
AKHDENYMPPEAADALKRAASDNPTEKTR
HHCCCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRRQRRLGLLLAALLCGGTALAFVLNAFRSNLVFFFSPTQVAAHEAPASRNFRLGGLVA
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCCEEECCEEC
PGSLKRDPENLTIRFVVTDTRHDIPVVYRGLLPDLFREGKGVVARGALDRDGTFVASEIL
CCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
AKHDENYMPPEAADALKRAASDNPTEKTR
HHCCCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA