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The map label for this gene is ccmF [H]

Identifier: 94312984

GI number: 94312984

Start: 622029

End: 624071

Strand: Reverse

Name: ccmF [H]

Synonym: Rmet_4056

Alternate gene names: 94312984

Gene position: 624071-622029 (Counterclockwise)

Preceding gene: 94312985

Following gene: 94312983

Centisome position: 24.19

GC content: 68.58

Gene sequence:

>2043_bases
ATGAATCCGGAACTGGGCCACTTCGCACTGATCCTGGCCATGCTCGTGGCGCTGGTGCTGGCAACGCTGCCGATGGTGGG
CGCGGCGCGCGGCAATGTTGCCTGGATGTGCCTTGCACGGCCCGCCGCCTTCCTGCATGGCACGCTGCTGATCGCGGCCT
ACCTCTCGCTGACATACGCTTTCGTCGACAACGACTTCAGCGTGCTCTATGTGGCGGCGAACTCTAACAGCGCGCTGCCA
CTGATCTACCGCATGGCGGCGGTATGGGGCGGCCATGAGGGGTCGATGCTGCTGTGGTCGCTGATGCTGGCGCTGTGGGC
AATGGCCGTGGCTGGCTTCAGCCGCCGCCTGCCACTGGCGTTCGTCGCCCGCGTGCTTGGCGTGATGGGGGGCATCAGCA
CCGGACTGCTGCTGTTCGTGCTGTTCGCATCGAATCCGTTCCTGCGTCTGTTGCCCCGCGCGATGGAGGGGCGCGACCTC
AATCCGCTGCTGCAGGACCCCGGCATGGTGTTCCATCCGCCATTCCTGTACATGGGCTACGTCGGCTTCGCGGTGGCATT
CTCATTCGCGGTGGCGGCCTTGCTTGAAGGACGACTCGACGCGGCCTGGGCACGCTGGTCGCGCCCGTGGACGATCCTGG
CGTGGATGTTCCTGACCATCGGCATCGCGATGGGCAGCATGTGGGCCTACTACGAACTGGGCTGGGGCGGCTGGTGGTTC
TGGGACCCGGTGGAGAACGCGTCGTTCATGCCCTGGCTGGCCGGCACCGCGCTGATCCACTCGCTGGCGGTCACCGAGAA
GCGCGGCGCGTTCCGCGCCTGGACCGCTCTGCTGGCGATCTTCACGTTCTCGCTGAGCCTGCTCGGCACGTTCCTGGTCC
GCTCTGGCGTGCTTACCTCGGTCCACGCGTTCGCGGTGGATCCCCGGCGCGGCATCTTCATCCTGACGTTGCTGGGACTG
GTCACGGGGCTGGCGCTCGCGCTATTCGCGTGGCGCGCGCCCCGGCTGACCCAGCGCACCGATTTCAACCTGACCTCGCG
CGAGTCTTTTCTGCTGGCCAATAACGTGCTGCTGGCCGTGGCCGCCTCGGCGGTGCTGCTCGGCACGCTGTATCCGCTGC
TGCTCGACGTGCTGGACCTCGGCAAGGTATCGGTCGGCCCCGAGTACTTCGAAGAAGTGTTCGTGCCGCTGATGGCCCCC
GCCGTGCTGCTGATGGGTGCCGCCCCGCTGGCACGCTGGGGACGCAGCGACCTGCCCGACATGGCCAGGCGACTGCGCTG
GGCGGCCGTGGCAAGTGTGGTCATCGCGCTTGGGCTGCTGGCCGTGCTGCGCAACAGCTCCGCCATGACCGGGCTCGGCC
TCACGCTGGCCGCGTGGTGTGCAATGAGCGGGCTGGCCAGCCTGGCCACGCAGATGCGGCACGCGCGGGACTGGCGCTCC
GGCCTGCGCCAGTTGCCGGCCGGCTACTACGGCATGTTGCTGGCCCACATCGGCGTGGGCGTGTTCATCACCGGCGTCAC
GCTGGTCAAGAGCCAGGAGAGCGTGCGCGAGTTGTCGATGCGCGTGGGCGATTCGGTCGCGGTTGGCGGCTACGATTTCC
GCTTCGACGGTGTGGCGCCGGTCAGGGGACCGAACTACGACGCGCTGCGGGGCACGGTCACGGTGACGCGGCAAGGCCGT
CCGGTCACCACGCTCGCCACCGAGCGGCGCGTCTACCGCAGCCAGGACATGCCGACCACCGAGGCCGCCATCGACACCGG
GCTCGCACGCGATCTCTATGTGGCGCTCGGCGATTCGTCGGATGCCACGTCCGCCGATGCCCGCTGGGCGCTGCGGGTCT
ACGTGAAGCCCTTCGTCTCGTGGGTCTGGGGCGGCTGCGCGTTGATGGCGCTGGGCGGACTCCTTGCCGCCAGCGACCGC
CGATATCGCGCGCGCCATCCGGCGGCAGCGGTCACGTCTGCGGTCACGGCCAATGACGATGCGGGGGCCCGGCCCGCCAC
GCCACCGCTGACGCTGCCTGCTGGCAAGGAGTCCGAAGCATGA

Upstream 100 bases:

>100_bases
CCAGCGAAATCCTGGCCAAGCATGACGAGAACTACATGCCGCCCGAAGCCGCCGACGCGCTCAAACGCGCCGCATCGGAC
AACCCCACGGAAAAAACGCG

Downstream 100 bases:

>100_bases
TGCGCTTCCTGCTTCCATTGGGCGTATTCCTGGCGATCGTGATCGCCCTGGCGGCGGGGTTGCGCCACGATCCGCGCGAG
CTGCCTTCTTCGCTGGTGGA

Product: cytochrome c-type biogenesis protein; heme lyase, CcmF subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MNPELGHFALILAMLVALVLATLPMVGAARGNVAWMCLARPAAFLHGTLLIAAYLSLTYAFVDNDFSVLYVAANSNSALP
LIYRMAAVWGGHEGSMLLWSLMLALWAMAVAGFSRRLPLAFVARVLGVMGGISTGLLLFVLFASNPFLRLLPRAMEGRDL
NPLLQDPGMVFHPPFLYMGYVGFAVAFSFAVAALLEGRLDAAWARWSRPWTILAWMFLTIGIAMGSMWAYYELGWGGWWF
WDPVENASFMPWLAGTALIHSLAVTEKRGAFRAWTALLAIFTFSLSLLGTFLVRSGVLTSVHAFAVDPRRGIFILTLLGL
VTGLALALFAWRAPRLTQRTDFNLTSRESFLLANNVLLAVAASAVLLGTLYPLLLDVLDLGKVSVGPEYFEEVFVPLMAP
AVLLMGAAPLARWGRSDLPDMARRLRWAAVASVVIALGLLAVLRNSSAMTGLGLTLAAWCAMSGLASLATQMRHARDWRS
GLRQLPAGYYGMLLAHIGVGVFITGVTLVKSQESVRELSMRVGDSVAVGGYDFRFDGVAPVRGPNYDALRGTVTVTRQGR
PVTTLATERRVYRSQDMPTTEAAIDTGLARDLYVALGDSSDATSADARWALRVYVKPFVSWVWGGCALMALGGLLAASDR
RYRARHPAAAVTSAVTANDDAGARPATPPLTLPAGKESEA

Sequences:

>Translated_680_residues
MNPELGHFALILAMLVALVLATLPMVGAARGNVAWMCLARPAAFLHGTLLIAAYLSLTYAFVDNDFSVLYVAANSNSALP
LIYRMAAVWGGHEGSMLLWSLMLALWAMAVAGFSRRLPLAFVARVLGVMGGISTGLLLFVLFASNPFLRLLPRAMEGRDL
NPLLQDPGMVFHPPFLYMGYVGFAVAFSFAVAALLEGRLDAAWARWSRPWTILAWMFLTIGIAMGSMWAYYELGWGGWWF
WDPVENASFMPWLAGTALIHSLAVTEKRGAFRAWTALLAIFTFSLSLLGTFLVRSGVLTSVHAFAVDPRRGIFILTLLGL
VTGLALALFAWRAPRLTQRTDFNLTSRESFLLANNVLLAVAASAVLLGTLYPLLLDVLDLGKVSVGPEYFEEVFVPLMAP
AVLLMGAAPLARWGRSDLPDMARRLRWAAVASVVIALGLLAVLRNSSAMTGLGLTLAAWCAMSGLASLATQMRHARDWRS
GLRQLPAGYYGMLLAHIGVGVFITGVTLVKSQESVRELSMRVGDSVAVGGYDFRFDGVAPVRGPNYDALRGTVTVTRQGR
PVTTLATERRVYRSQDMPTTEAAIDTGLARDLYVALGDSSDATSADARWALRVYVKPFVSWVWGGCALMALGGLLAASDR
RYRARHPAAAVTSAVTANDDAGARPATPPLTLPAGKESEA
>Mature_680_residues
MNPELGHFALILAMLVALVLATLPMVGAARGNVAWMCLARPAAFLHGTLLIAAYLSLTYAFVDNDFSVLYVAANSNSALP
LIYRMAAVWGGHEGSMLLWSLMLALWAMAVAGFSRRLPLAFVARVLGVMGGISTGLLLFVLFASNPFLRLLPRAMEGRDL
NPLLQDPGMVFHPPFLYMGYVGFAVAFSFAVAALLEGRLDAAWARWSRPWTILAWMFLTIGIAMGSMWAYYELGWGGWWF
WDPVENASFMPWLAGTALIHSLAVTEKRGAFRAWTALLAIFTFSLSLLGTFLVRSGVLTSVHAFAVDPRRGIFILTLLGL
VTGLALALFAWRAPRLTQRTDFNLTSRESFLLANNVLLAVAASAVLLGTLYPLLLDVLDLGKVSVGPEYFEEVFVPLMAP
AVLLMGAAPLARWGRSDLPDMARRLRWAAVASVVIALGLLAVLRNSSAMTGLGLTLAAWCAMSGLASLATQMRHARDWRS
GLRQLPAGYYGMLLAHIGVGVFITGVTLVKSQESVRELSMRVGDSVAVGGYDFRFDGVAPVRGPNYDALRGTVTVTRQGR
PVTTLATERRVYRSQDMPTTEAAIDTGLARDLYVALGDSSDATSADARWALRVYVKPFVSWVWGGCALMALGGLLAASDR
RYRARHPAAAVTSAVTANDDAGARPATPPLTLPAGKESEA

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=648, Percent_Identity=54.1666666666667, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI1790511, Length=365, Percent_Identity=48.4931506849315, Blast_Score=298, Evalue=7e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 73411; Mature: 73411

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPELGHFALILAMLVALVLATLPMVGAARGNVAWMCLARPAAFLHGTLLIAAYLSLTYA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
FVDNDFSVLYVAANSNSALPLIYRMAAVWGGHEGSMLLWSLMLALWAMAVAGFSRRLPLA
EECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
FVARVLGVMGGISTGLLLFVLFASNPFLRLLPRAMEGRDLNPLLQDPGMVFHPPFLYMGY
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCEECCHHHHHHH
VGFAVAFSFAVAALLEGRLDAAWARWSRPWTILAWMFLTIGIAMGSMWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEE
WDPVENASFMPWLAGTALIHSLAVTEKRGAFRAWTALLAIFTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFAVDPRRGIFILTLLGLVTGLALALFAWRAPRLTQRTDFNLTSRESFLLANNVLLAV
HHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AASAVLLGTLYPLLLDVLDLGKVSVGPEYFEEVFVPLMAPAVLLMGAAPLARWGRSDLPD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHH
MARRLRWAAVASVVIALGLLAVLRNSSAMTGLGLTLAAWCAMSGLASLATQMRHARDWRS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRQLPAGYYGMLLAHIGVGVFITGVTLVKSQESVRELSMRVGDSVAVGGYDFRFDGVAP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCEEEEECCCCC
VRGPNYDALRGTVTVTRQGRPVTTLATERRVYRSQDMPTTEAAIDTGLARDLYVALGDSS
CCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCCHHHHHHHCCHHEEEEEECCCC
DATSADARWALRVYVKPFVSWVWGGCALMALGGLLAASDRRYRARHPAAAVTSAVTANDD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHCCCCC
AGARPATPPLTLPAGKESEA
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPELGHFALILAMLVALVLATLPMVGAARGNVAWMCLARPAAFLHGTLLIAAYLSLTYA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
FVDNDFSVLYVAANSNSALPLIYRMAAVWGGHEGSMLLWSLMLALWAMAVAGFSRRLPLA
EECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
FVARVLGVMGGISTGLLLFVLFASNPFLRLLPRAMEGRDLNPLLQDPGMVFHPPFLYMGY
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCEECCHHHHHHH
VGFAVAFSFAVAALLEGRLDAAWARWSRPWTILAWMFLTIGIAMGSMWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEE
WDPVENASFMPWLAGTALIHSLAVTEKRGAFRAWTALLAIFTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFAVDPRRGIFILTLLGLVTGLALALFAWRAPRLTQRTDFNLTSRESFLLANNVLLAV
HHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AASAVLLGTLYPLLLDVLDLGKVSVGPEYFEEVFVPLMAPAVLLMGAAPLARWGRSDLPD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHH
MARRLRWAAVASVVIALGLLAVLRNSSAMTGLGLTLAAWCAMSGLASLATQMRHARDWRS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRQLPAGYYGMLLAHIGVGVFITGVTLVKSQESVRELSMRVGDSVAVGGYDFRFDGVAP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCEEEEECCCCC
VRGPNYDALRGTVTVTRQGRPVTTLATERRVYRSQDMPTTEAAIDTGLARDLYVALGDSS
CCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCCHHHHHHHCCHHEEEEEECCCC
DATSADARWALRVYVKPFVSWVWGGCALMALGGLLAASDRRYRARHPAAAVTSAVTANDD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHCCCCC
AGARPATPPLTLPAGKESEA
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]