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The map label for this gene is gbpR [H]

Identifier: 94312961

GI number: 94312961

Start: 601441

End: 602421

Strand: Reverse

Name: gbpR [H]

Synonym: Rmet_4033

Alternate gene names: 94312961

Gene position: 602421-601441 (Counterclockwise)

Preceding gene: 94312970

Following gene: 94312960

Centisome position: 23.35

GC content: 67.69

Gene sequence:

>981_bases
ATGCATTACCATTTGGTTATACAACTCCTTCCCATTGCCGCCATGCCGATCGCCACCGACAAGCTGCTGCACAACATCGT
CTCCCGGCTGCGCCTGCGTCACCTGCCGCTGCTGCTTGCGCTCGAGCAGCAGCGCTCGATCTCGCGCGTGGCGGCCGAAA
TGAACCTGTCACAGCCGGCCGTGACCAAGGCGCTGCGGGAAATCGAGGACATTTTCACCACGCCGCTGTTCACCCGCACC
CGCAACGGCCTGGAGCCAACCGCAACCGGCACGGCAGTGCTGGGCCATGCGCGCATGGCGCTGGCCGACGCTGACGCGCT
GGGGCGCGAGCTGGCCGTGATCGAAGCCGGTCTGAGCGGCCGGCTGCGCATCGGCGCCATCCCCTATACGGCGCGCGCCG
TGCTCGATGCCGCGCTCGCCTACGGGCTGAACCGCACGCCGCGCATCTCGGTGCTGGTCAGGGAGGGCACCACCGACGAA
CTGGTCGTCGCGCTGCGCCAGCATGAACTCGACTGCGCGATCGCGCGCTCGTTCTACCTGGCGGGGGAAGACATCGTCCA
GCAACCGCTCTATCGCGAGGAGCCGGTGCTCGTGGTACCGTCACGCGCTGCCGCGCGGCTGTCGCGCGGCGGACTGGACT
GGAAGCGGCTGGCCGAGCTCGACTGGATTCTGCCGCCGCACCATACGCCGGTGCGCCGCACGATCAATACGATGTTCGCA
CTGGCCGGCGTGGCGCCGCCGCTGCCGATCGTCGAGACCTATTCGGTCAAGCCCATGGCCACGCTGCTACGCAGCCAGCC
GCACGTGATCACGATCGTGCCGAGGTCAGTTGGGGCCGAACTGGTCGAACTGGGCGATGCCGCGATGCTGCCGTTCTCGC
TCTCGTGGGACCTGCCACCCGTGGGCTTGATGTGGCGGCGCGAGTCGCAGGAAAACGAACTTGTGACGGGGCTGGCAGCG
GCACTGCGCCAGGCCATCTGA

Upstream 100 bases:

>100_bases
CAATTGGTGCAGTCGTCTTCTGAAAATGACACAATGGCTGGATCGGAATGTATTCGAGTATAGGCAAGTGAAATAACCAC
CAAGAGCCAAATACTTATCG

Downstream 100 bases:

>100_bases
ATCGACAGCAGGAAAAAGGAAAAGGCTGAAAACCGGGATGAAAACCGTCGGACTCTATCTGCTTACCGCGCTGGCCGAGA
TTCTCGGCTGCTATCTGCCC

Product: putative LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MHYHLVIQLLPIAAMPIATDKLLHNIVSRLRLRHLPLLLALEQQRSISRVAAEMNLSQPAVTKALREIEDIFTTPLFTRT
RNGLEPTATGTAVLGHARMALADADALGRELAVIEAGLSGRLRIGAIPYTARAVLDAALAYGLNRTPRISVLVREGTTDE
LVVALRQHELDCAIARSFYLAGEDIVQQPLYREEPVLVVPSRAAARLSRGGLDWKRLAELDWILPPHHTPVRRTINTMFA
LAGVAPPLPIVETYSVKPMATLLRSQPHVITIVPRSVGAELVELGDAAMLPFSLSWDLPPVGLMWRRESQENELVTGLAA
ALRQAI

Sequences:

>Translated_326_residues
MHYHLVIQLLPIAAMPIATDKLLHNIVSRLRLRHLPLLLALEQQRSISRVAAEMNLSQPAVTKALREIEDIFTTPLFTRT
RNGLEPTATGTAVLGHARMALADADALGRELAVIEAGLSGRLRIGAIPYTARAVLDAALAYGLNRTPRISVLVREGTTDE
LVVALRQHELDCAIARSFYLAGEDIVQQPLYREEPVLVVPSRAAARLSRGGLDWKRLAELDWILPPHHTPVRRTINTMFA
LAGVAPPLPIVETYSVKPMATLLRSQPHVITIVPRSVGAELVELGDAAMLPFSLSWDLPPVGLMWRRESQENELVTGLAA
ALRQAI
>Mature_326_residues
MHYHLVIQLLPIAAMPIATDKLLHNIVSRLRLRHLPLLLALEQQRSISRVAAEMNLSQPAVTKALREIEDIFTTPLFTRT
RNGLEPTATGTAVLGHARMALADADALGRELAVIEAGLSGRLRIGAIPYTARAVLDAALAYGLNRTPRISVLVREGTTDE
LVVALRQHELDCAIARSFYLAGEDIVQQPLYREEPVLVVPSRAAARLSRGGLDWKRLAELDWILPPHHTPVRRTINTMFA
LAGVAPPLPIVETYSVKPMATLLRSQPHVITIVPRSVGAELVELGDAAMLPFSLSWDLPPVGLMWRRESQENELVTGLAA
ALRQAI

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=299, Percent_Identity=22.742474916388, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081904, Length=230, Percent_Identity=28.695652173913, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=216, Percent_Identity=25.462962962963, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790399, Length=169, Percent_Identity=27.2189349112426, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=24.5967741935484, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI2367136, Length=150, Percent_Identity=27.3333333333333, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35796; Mature: 35796

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYHLVIQLLPIAAMPIATDKLLHNIVSRLRLRHLPLLLALEQQRSISRVAAEMNLSQPA
CCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHH
VTKALREIEDIFTTPLFTRTRNGLEPTATGTAVLGHARMALADADALGRELAVIEAGLSG
HHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
RLRIGAIPYTARAVLDAALAYGLNRTPRISVLVREGTTDELVVALRQHELDCAIARSFYL
CEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
AGEDIVQQPLYREEPVLVVPSRAAARLSRGGLDWKRLAELDWILPPHHTPVRRTINTMFA
CCHHHHHCCCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LAGVAPPLPIVETYSVKPMATLLRSQPHVITIVPRSVGAELVELGDAAMLPFSLSWDLPP
HHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECHHHCHHHHHCCCCEECCEEECCCCCC
VGLMWRRESQENELVTGLAAALRQAI
CCCEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHYHLVIQLLPIAAMPIATDKLLHNIVSRLRLRHLPLLLALEQQRSISRVAAEMNLSQPA
CCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHH
VTKALREIEDIFTTPLFTRTRNGLEPTATGTAVLGHARMALADADALGRELAVIEAGLSG
HHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
RLRIGAIPYTARAVLDAALAYGLNRTPRISVLVREGTTDELVVALRQHELDCAIARSFYL
CEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
AGEDIVQQPLYREEPVLVVPSRAAARLSRGGLDWKRLAELDWILPPHHTPVRRTINTMFA
CCHHHHHCCCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LAGVAPPLPIVETYSVKPMATLLRSQPHVITIVPRSVGAELVELGDAAMLPFSLSWDLPP
HHCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECHHHCHHHHHCCCCEECCEEECCCCCC
VGLMWRRESQENELVTGLAAALRQAI
CCCEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]