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The map label for this gene is yciR [C]

Identifier: 94312902

GI number: 94312902

Start: 538450

End: 539775

Strand: Direct

Name: yciR [C]

Synonym: Rmet_3974

Alternate gene names: 94312902

Gene position: 538450-539775 (Clockwise)

Preceding gene: 94312893

Following gene: 94312903

Centisome position: 20.87

GC content: 66.89

Gene sequence:

>1326_bases
ATGGTGGCCAAGTCGGAGGCGCAGGCGACTGGTGCCTTGCCGCCGGCGGATGTTGATCCGCTGACCGGCGTGGTCGCTCG
CCAGTCATTCTTGAATCGGCTGGAAACGCGCCTGCATAGCGAGGCGACGCCCCGCTTTTCCCTGTTGCTGGTTGGCATCG
ACGATTTCCGCGCGTTCAACGACATGCATGGCCACATGGAGGGCGATGCAATCCTCCTGCAGGTTGCCCGCCGGCTGCGT
GATGCCGCGCCGCGCGACGCCGTGGTTGGCCGCGTGGGCGGCGACGAGTTCGCCGTACTGCTGACCTCCATCTCGGACCC
GACGCTGGTGCGGCACGTAAGCGCCGCCATTCTGTCGATGCTGTCTGCCCCCCACGAACTAAATGGCCGCCGCCACCATG
TGCTGGCCAGTCTGGGCGCGTGCGTGATGCCGACCGGCGGAGATACCACTTCCGACGTGCTGGCTGCCGCCAGCCTGGCG
CTGGCCCGGGCCAAGCACGATGGCGGGCGCACGATTCGCTTCTTCAAGCCGCAGATGCGCACGGACGTGATGACGCGACT
GTCGCTCGTCCAGGCCTTGCGGGAAGCCTATGCCCAGCGGCAGTTCGAACTGCTGTACCAGCCGCAGGTGGATCTGCGGG
ATGGCCGCGTGCTGGGCGCGGAGGCACTGATGCGCTGGCGGCATCCGACGCTGGGCCTGCTCGCCCCGGCCGCGTTTATC
GACGCCCTGGCCGCGAGCAGCGTGGCGGCGGACGTCGGTATGTGGCTACTGCACACGGCTTGCGCGCAGGCGCGGGCGTG
GTCGCTGACATTTCCCGACGCCCCCCGGGTGGCGATCAACCTGTTTGCCGCCCAGCTGTCCGAAAGCCGGTTGCTGACCG
AGGTCCGCCATGTGCTGCGGGCGCTCGAGCTGCCGCCCGACCGGCTGGAGATCGAGATCACCGAGACCATCGCACTGCAG
CAGGGCGATGAGGTGTCGGGCCAACTCCAGGCGCTGCGCCGCGATGGCGTGACACTGACCTGCGACGATTTTGGCACCGG
CTATGCATCACTGAGCTTCCTGAAGTCCTTCCCTGTGGACCGGCTCAAGATCGATCAGTCGTTTATTCGCAACGTCACGC
AAGACAGTGTCGATGCGGCGATCGTGCGTTCGGTCATCAACGTCGGGCAGAGCCTGCGCATCGGCGTGGTCGCCGAAGGG
GTGGAGAATGCCGCCCAACGGGAATTCCTGCTGGCCAACGGATGCGTCGAGGCGCAGGGCTATCTCTATGGGCGCCCGAT
GTCGGCTGACCTCCTGACGGAGCACCTCCGCCACCAGCCGCGCTGA

Upstream 100 bases:

>100_bases
TGCGCCGGAAATTGGAAGCGCTTGCATTTTCCAAGGTTTTCGTCACACTTGCCAAATAGCTTGAGCAGGGAACATGTTCA
TCACAACAGATAGGGCAGGG

Downstream 100 bases:

>100_bases
CGCCGGCGACGGATTTGTTTCCACCTTTATCCCCCATCGCCTGGCCGGGCTGCGGGGAAATATGTACTTACAAAGTCCGG
TACACAGGTAGAACACTGCA

Product: putative diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MVAKSEAQATGALPPADVDPLTGVVARQSFLNRLETRLHSEATPRFSLLLVGIDDFRAFNDMHGHMEGDAILLQVARRLR
DAAPRDAVVGRVGGDEFAVLLTSISDPTLVRHVSAAILSMLSAPHELNGRRHHVLASLGACVMPTGGDTTSDVLAAASLA
LARAKHDGGRTIRFFKPQMRTDVMTRLSLVQALREAYAQRQFELLYQPQVDLRDGRVLGAEALMRWRHPTLGLLAPAAFI
DALAASSVAADVGMWLLHTACAQARAWSLTFPDAPRVAINLFAAQLSESRLLTEVRHVLRALELPPDRLEIEITETIALQ
QGDEVSGQLQALRRDGVTLTCDDFGTGYASLSFLKSFPVDRLKIDQSFIRNVTQDSVDAAIVRSVINVGQSLRIGVVAEG
VENAAQREFLLANGCVEAQGYLYGRPMSADLLTEHLRHQPR

Sequences:

>Translated_441_residues
MVAKSEAQATGALPPADVDPLTGVVARQSFLNRLETRLHSEATPRFSLLLVGIDDFRAFNDMHGHMEGDAILLQVARRLR
DAAPRDAVVGRVGGDEFAVLLTSISDPTLVRHVSAAILSMLSAPHELNGRRHHVLASLGACVMPTGGDTTSDVLAAASLA
LARAKHDGGRTIRFFKPQMRTDVMTRLSLVQALREAYAQRQFELLYQPQVDLRDGRVLGAEALMRWRHPTLGLLAPAAFI
DALAASSVAADVGMWLLHTACAQARAWSLTFPDAPRVAINLFAAQLSESRLLTEVRHVLRALELPPDRLEIEITETIALQ
QGDEVSGQLQALRRDGVTLTCDDFGTGYASLSFLKSFPVDRLKIDQSFIRNVTQDSVDAAIVRSVINVGQSLRIGVVAEG
VENAAQREFLLANGCVEAQGYLYGRPMSADLLTEHLRHQPR
>Mature_441_residues
MVAKSEAQATGALPPADVDPLTGVVARQSFLNRLETRLHSEATPRFSLLLVGIDDFRAFNDMHGHMEGDAILLQVARRLR
DAAPRDAVVGRVGGDEFAVLLTSISDPTLVRHVSAAILSMLSAPHELNGRRHHVLASLGACVMPTGGDTTSDVLAAASLA
LARAKHDGGRTIRFFKPQMRTDVMTRLSLVQALREAYAQRQFELLYQPQVDLRDGRVLGAEALMRWRHPTLGLLAPAAFI
DALAASSVAADVGMWLLHTACAQARAWSLTFPDAPRVAINLFAAQLSESRLLTEVRHVLRALELPPDRLEIEITETIALQ
QGDEVSGQLQALRRDGVTLTCDDFGTGYASLSFLKSFPVDRLKIDQSFIRNVTQDSVDAAIVRSVINVGQSLRIGVVAEG
VENAAQREFLLANGCVEAQGYLYGRPMSADLLTEHLRHQPR

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=414, Percent_Identity=31.6425120772947, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI87081921, Length=412, Percent_Identity=31.5533980582524, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI226510982, Length=397, Percent_Identity=28.463476070529, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI87081845, Length=251, Percent_Identity=29.8804780876494, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1787055, Length=291, Percent_Identity=28.1786941580756, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=34.2629482071713, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790496, Length=254, Percent_Identity=29.5275590551181, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=30.5785123966942, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786507, Length=240, Percent_Identity=28.3333333333333, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081980, Length=242, Percent_Identity=31.8181818181818, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=28.9915966386555, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=29.3388429752066, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787410, Length=175, Percent_Identity=29.1428571428571, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788381, Length=390, Percent_Identity=24.1025641025641, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788956, Length=139, Percent_Identity=30.9352517985612, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081881, Length=158, Percent_Identity=31.6455696202532, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787262, Length=153, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 48038; Mature: 48038

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKSEAQATGALPPADVDPLTGVVARQSFLNRLETRLHSEATPRFSLLLVGIDDFRAFN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHH
DMHGHMEGDAILLQVARRLRDAAPRDAVVGRVGGDEFAVLLTSISDPTLVRHVSAAILSM
HHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHH
LSAPHELNGRRHHVLASLGACVMPTGGDTTSDVLAAASLALARAKHDGGRTIRFFKPQMR
HCCCHHCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
TDVMTRLSLVQALREAYAQRQFELLYQPQVDLRDGRVLGAEALMRWRHPTLGLLAPAAFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHCCCCHHHHHHHHHH
DALAASSVAADVGMWLLHTACAQARAWSLTFPDAPRVAINLFAAQLSESRLLTEVRHVLR
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALELPPDRLEIEITETIALQQGDEVSGQLQALRRDGVTLTCDDFGTGYASLSFLKSFPVD
HHCCCCCCEEEEEEHEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCH
RLKIDQSFIRNVTQDSVDAAIVRSVINVGQSLRIGVVAEGVENAAQREFLLANGCVEAQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
YLYGRPMSADLLTEHLRHQPR
EEECCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MVAKSEAQATGALPPADVDPLTGVVARQSFLNRLETRLHSEATPRFSLLLVGIDDFRAFN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHH
DMHGHMEGDAILLQVARRLRDAAPRDAVVGRVGGDEFAVLLTSISDPTLVRHVSAAILSM
HHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHH
LSAPHELNGRRHHVLASLGACVMPTGGDTTSDVLAAASLALARAKHDGGRTIRFFKPQMR
HCCCHHCCCCHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
TDVMTRLSLVQALREAYAQRQFELLYQPQVDLRDGRVLGAEALMRWRHPTLGLLAPAAFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHCCCCHHHHHHHHHH
DALAASSVAADVGMWLLHTACAQARAWSLTFPDAPRVAINLFAAQLSESRLLTEVRHVLR
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALELPPDRLEIEITETIALQQGDEVSGQLQALRRDGVTLTCDDFGTGYASLSFLKSFPVD
HHCCCCCCEEEEEEHEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCH
RLKIDQSFIRNVTQDSVDAAIVRSVINVGQSLRIGVVAEGVENAAQREFLLANGCVEAQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
YLYGRPMSADLLTEHLRHQPR
EEECCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]