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The map label for this gene is mcpB [H]

Identifier: 94312901

GI number: 94312901

Start: 536556

End: 538376

Strand: Reverse

Name: mcpB [H]

Synonym: Rmet_3973

Alternate gene names: 94312901

Gene position: 538376-536556 (Counterclockwise)

Preceding gene: 291481503

Following gene: 94312900

Centisome position: 20.87

GC content: 65.73

Gene sequence:

>1821_bases
ATGCAAGCGCTTCCAATTTCCGGCGCAACGGCGCAACGCCCCGGGCACCGCGTTGAAATGGCTTGGGCGTTACAGTACCC
TACGCCGCAAAAGGCTACCACCCAAACGAGGGATACCCCCAACTGGGTGACGGCGCCCCCGCCCCAAAGCATGACCCAGC
CGGCCCCAACCCCGGCGGCTTCACCGGAGACGATCCTGATCGTGACCCACTGGACCATCCGCACCCGCATTCTGGCGAGC
TTCACCATCATCCTGCTGGTCATGGCCCTGATGAGCGGCGTCGCCTACCGAAGGCTGTCCGCCATCGAGCACGAAACCAC
CGTGATGCGCACCGATGCGCTGCCGGGCCTGAACTTCAGCGCCGGAATGCGCGGGGTCTGGGGCGAAATCTACGTGCTGG
CCTGGCAGACGGTAACCGCGGCCGATGCTCCCCAACGCGCCCGCCTGCTTGCGCAGACGCAGGACGCCATGCAGCGTCTG
GACCGTTTGGAACAGCAGTACGACGCCACCATCGTCCGTGACGACGACCGTGCCCGCTTCCACAACTATCAGGCCGTCCG
CGCCCGGTACCAGCAGGCCGCCCAGCCGTACCTTGACCCCGCTCAGTGGAAGGATGCCGCCACGGCCCAGGCCGCCTTGC
GCGGCAGCGCGCACGACCTCTGGTCTGATGGCCGGAAGCTGCTGCAGGACATCGTCGACGACAACGGCAAGGTCAATGAG
CGGGCCTCCACTGGCATCGTCGACTCGGTGGTAACGGCTAAGGTCAGTATCGAAGTGGCATTCGGCATCGCCGTGCTCGC
CGCCCTGATCGCCGGCTATCAATTGCTACGCGCCATTACGGTGCCGATGGGCAAGATCGTCTCGCTGCTGAAGACCATGC
GCGGCGGCGACCTGCGCCAGCGGATGGTGTTGCATCGGCGAGACGAGTTCCAGGCCGTGGAGGAAGGTTTCAACCAGATG
GCCGACGAGCTGACGTCGCTGGTCGGACAAGCGCAACGCTCGGCAATCCAGGTCACGACCTCGGTCAACGAGATCGCCGC
CACGGCGCGCCAGCAGCAGGCCACCGCCACCGAAACGGCCGCCACGACCACGCAGATTGGCGCGACTTCGCGCGAGATCT
CGGCTACCGCGCGCGACCTGGTCCGCACCATGAGCGAGGTTTCCCACGCCGCCGACCAGACAGCCGGACTGGCTGGCACA
GGTCAGGTGGGTCTGTCGCGCATGGAAGCGACGATGAACCACGTGATGGAAGCCGCCGGCTCGGTCAACGCCCGTCTGGC
CACGCTCAACGAGAAGGCCGGCAATATCAACCAGGTGGTGACCACCATCGCGCGCGTAGCGGACCAGACCAACCTGCTGT
CGCTGAACGCCGCGATCGAGGCCGAGAAGGCTGGCGAGTACGGCCGCGGATTCTCCGTGGTGGCCACCGAGATTCGGCGC
CTGGCGGACCAGACCGCCGTGGCCACCTACGACATCGAACAGATCGTGCGCGAGATCCAGTCGGCCGTGGCCGCCGGGGT
GATGGGCATGGACAAGTTCTCGGAGGAAGTCCGCCGCGGCATGTCCGAGGTCACCCAGGTTGGCGACCAGCTTTCGCAGA
TCATTGGGCAGGTTCAGTCCCTGGCGCCACGCGTGCAGATGGTCAACGAAGGGATGCAGGCGCAGGCAGGCGGTGCCGAG
CAGATCAATCAGGCGCTGATCCAGTTGTCCGAAGCCGCGCAGCAGACGGTGGAGTCGCTGCGTCAGTCCAGCCAGGCCAT
CGACGAACTGACGCTGGTTTCCAACGAACTGCGCAGCGGCGTCTCGCGCTTCAAAGTCTGA

Upstream 100 bases:

>100_bases
CGCCTGCGCCTCCGACTTGGCCACCATCCCTGCCCTATCTGTTGTGATGAACATGTTCCCTGCTCAAGCTATTTGGCAAG
TGTGACGAAAACCTTGGAAA

Downstream 100 bases:

>100_bases
ACAGGCGATCCCGGAGCCACCATCGCCATGGCCCTTTTCCTGCTCTTCCGCATCGGCGCCGATCGCTACGCGCTCGATAG
CGCCGAGGTGGCCGAGGTCC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MQALPISGATAQRPGHRVEMAWALQYPTPQKATTQTRDTPNWVTAPPPQSMTQPAPTPAASPETILIVTHWTIRTRILAS
FTIILLVMALMSGVAYRRLSAIEHETTVMRTDALPGLNFSAGMRGVWGEIYVLAWQTVTAADAPQRARLLAQTQDAMQRL
DRLEQQYDATIVRDDDRARFHNYQAVRARYQQAAQPYLDPAQWKDAATAQAALRGSAHDLWSDGRKLLQDIVDDNGKVNE
RASTGIVDSVVTAKVSIEVAFGIAVLAALIAGYQLLRAITVPMGKIVSLLKTMRGGDLRQRMVLHRRDEFQAVEEGFNQM
ADELTSLVGQAQRSAIQVTTSVNEIAATARQQQATATETAATTTQIGATSREISATARDLVRTMSEVSHAADQTAGLAGT
GQVGLSRMEATMNHVMEAAGSVNARLATLNEKAGNINQVVTTIARVADQTNLLSLNAAIEAEKAGEYGRGFSVVATEIRR
LADQTAVATYDIEQIVREIQSAVAAGVMGMDKFSEEVRRGMSEVTQVGDQLSQIIGQVQSLAPRVQMVNEGMQAQAGGAE
QINQALIQLSEAAQQTVESLRQSSQAIDELTLVSNELRSGVSRFKV

Sequences:

>Translated_606_residues
MQALPISGATAQRPGHRVEMAWALQYPTPQKATTQTRDTPNWVTAPPPQSMTQPAPTPAASPETILIVTHWTIRTRILAS
FTIILLVMALMSGVAYRRLSAIEHETTVMRTDALPGLNFSAGMRGVWGEIYVLAWQTVTAADAPQRARLLAQTQDAMQRL
DRLEQQYDATIVRDDDRARFHNYQAVRARYQQAAQPYLDPAQWKDAATAQAALRGSAHDLWSDGRKLLQDIVDDNGKVNE
RASTGIVDSVVTAKVSIEVAFGIAVLAALIAGYQLLRAITVPMGKIVSLLKTMRGGDLRQRMVLHRRDEFQAVEEGFNQM
ADELTSLVGQAQRSAIQVTTSVNEIAATARQQQATATETAATTTQIGATSREISATARDLVRTMSEVSHAADQTAGLAGT
GQVGLSRMEATMNHVMEAAGSVNARLATLNEKAGNINQVVTTIARVADQTNLLSLNAAIEAEKAGEYGRGFSVVATEIRR
LADQTAVATYDIEQIVREIQSAVAAGVMGMDKFSEEVRRGMSEVTQVGDQLSQIIGQVQSLAPRVQMVNEGMQAQAGGAE
QINQALIQLSEAAQQTVESLRQSSQAIDELTLVSNELRSGVSRFKV
>Mature_606_residues
MQALPISGATAQRPGHRVEMAWALQYPTPQKATTQTRDTPNWVTAPPPQSMTQPAPTPAASPETILIVTHWTIRTRILAS
FTIILLVMALMSGVAYRRLSAIEHETTVMRTDALPGLNFSAGMRGVWGEIYVLAWQTVTAADAPQRARLLAQTQDAMQRL
DRLEQQYDATIVRDDDRARFHNYQAVRARYQQAAQPYLDPAQWKDAATAQAALRGSAHDLWSDGRKLLQDIVDDNGKVNE
RASTGIVDSVVTAKVSIEVAFGIAVLAALIAGYQLLRAITVPMGKIVSLLKTMRGGDLRQRMVLHRRDEFQAVEEGFNQM
ADELTSLVGQAQRSAIQVTTSVNEIAATARQQQATATETAATTTQIGATSREISATARDLVRTMSEVSHAADQTAGLAGT
GQVGLSRMEATMNHVMEAAGSVNARLATLNEKAGNINQVVTTIARVADQTNLLSLNAAIEAEKAGEYGRGFSVVATEIRR
LADQTAVATYDIEQIVREIQSAVAAGVMGMDKFSEEVRRGMSEVTQVGDQLSQIIGQVQSLAPRVQMVNEGMQAQAGGAE
QINQALIQLSEAAQQTVESLRQSSQAIDELTLVSNELRSGVSRFKV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=333, Percent_Identity=28.8288288288288, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI2367378, Length=328, Percent_Identity=28.0487804878049, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788195, Length=311, Percent_Identity=27.6527331189711, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787690, Length=350, Percent_Identity=28, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789453, Length=334, Percent_Identity=23.9520958083832, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 65627; Mature: 65627

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALPISGATAQRPGHRVEMAWALQYPTPQKATTQTRDTPNWVTAPPPQSMTQPAPTPAA
CCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPETILIVTHWTIRTRILASFTIILLVMALMSGVAYRRLSAIEHETTVMRTDALPGLNFS
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
AGMRGVWGEIYVLAWQTVTAADAPQRARLLAQTQDAMQRLDRLEQQYDATIVRDDDRARF
CCCCCCCHHEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
HNYQAVRARYQQAAQPYLDPAQWKDAATAQAALRGSAHDLWSDGRKLLQDIVDDNGKVNE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
RASTGIVDSVVTAKVSIEVAFGIAVLAALIAGYQLLRAITVPMGKIVSLLKTMRGGDLRQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
RMVLHRRDEFQAVEEGFNQMADELTSLVGQAQRSAIQVTTSVNEIAATARQQQATATETA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHH
ATTTQIGATSREISATARDLVRTMSEVSHAADQTAGLAGTGQVGLSRMEATMNHVMEAAG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
SVNARLATLNEKAGNINQVVTTIARVADQTNLLSLNAAIEAEKAGEYGRGFSVVATEIRR
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHH
LADQTAVATYDIEQIVREIQSAVAAGVMGMDKFSEEVRRGMSEVTQVGDQLSQIIGQVQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPRVQMVNEGMQAQAGGAEQINQALIQLSEAAQQTVESLRQSSQAIDELTLVSNELRSG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRFKV
HHHCCC
>Mature Secondary Structure
MQALPISGATAQRPGHRVEMAWALQYPTPQKATTQTRDTPNWVTAPPPQSMTQPAPTPAA
CCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPETILIVTHWTIRTRILASFTIILLVMALMSGVAYRRLSAIEHETTVMRTDALPGLNFS
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
AGMRGVWGEIYVLAWQTVTAADAPQRARLLAQTQDAMQRLDRLEQQYDATIVRDDDRARF
CCCCCCCHHEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
HNYQAVRARYQQAAQPYLDPAQWKDAATAQAALRGSAHDLWSDGRKLLQDIVDDNGKVNE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
RASTGIVDSVVTAKVSIEVAFGIAVLAALIAGYQLLRAITVPMGKIVSLLKTMRGGDLRQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
RMVLHRRDEFQAVEEGFNQMADELTSLVGQAQRSAIQVTTSVNEIAATARQQQATATETA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHH
ATTTQIGATSREISATARDLVRTMSEVSHAADQTAGLAGTGQVGLSRMEATMNHVMEAAG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
SVNARLATLNEKAGNINQVVTTIARVADQTNLLSLNAAIEAEKAGEYGRGFSVVATEIRR
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHH
LADQTAVATYDIEQIVREIQSAVAAGVMGMDKFSEEVRRGMSEVTQVGDQLSQIIGQVQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPRVQMVNEGMQAQAGGAEQINQALIQLSEAAQQTVESLRQSSQAIDELTLVSNELRSG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRFKV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]