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The map label for this gene is btr [H]

Identifier: 94312876

GI number: 94312876

Start: 504836

End: 505495

Strand: Reverse

Name: btr [H]

Synonym: Rmet_3948

Alternate gene names: 94312876

Gene position: 505495-504836 (Counterclockwise)

Preceding gene: 94312878

Following gene: 94312871

Centisome position: 19.59

GC content: 65.0

Gene sequence:

>660_bases
TTGCTGCCCGACAGACCAGCATTAAGCCCCGAGCGCAAGCACCTGCAAGCCGGCGAGGCGCTATTCAGGCAGGACCAACC
GGTACGCGCCGTCTACCCATTGCGCCACGGCGGCATCAAGCGGATGTACGAATCGGCACTTGGATGGCGGCAATTGACCG
GCTTCATGCTCCCCGGTGACGTAGCCGGCCTCGAGCCGAATGACGCGCCGCAGTTCGGCACGAGCGCGATTGCCCTGCAG
GCATCCGAATGCTGTGTGGTGCCACTGGAGACAGCGAAGCGCTGCGAGGAAGATCCGGCGGTTCACGCCGCCTTGCTCGC
GCTACTTCACCGCGACGCCTTGCGGCAGCGCGAGTTGCTGGTGACCATCGGCTCAATGAAGGCCGCGCAGAGGCTGGCCA
TGCTATTGCTCGATCAGGCTGCGGAACACCGCCGCCGCGGCACCGACGGGGGAGAAGTCATGCTGGCGATGACTCGCAAC
GATATCGCCAGCTACCTGGGCCTGACGCTGGAGACGGTCTCGCGGCTTCTGTCCCGCTTTGCGTCCGTCGGGCTGATCAC
GGTGCGGCACCGTCAGCTTCGTATCGTCGACGAGAAAGGGCTGTCAGACGTCCACGCCGAAGCAGACCGCATCACGCTGC
GCGGTCCGGATCCAGCTTAG

Upstream 100 bases:

>100_bases
CTGCCAGGAGGCAATACCACTGGACCACCAAGCCCCCAGCGCCTCATGCTGCACCCTGTGCCCGTTCCAGTCCGTTTGCG
CAAGTGCACACGGAGGCACC

Downstream 100 bases:

>100_bases
ACGCAATTGCCGGAGACTTCGGATCCGGAATCAGCGATCTGCAGCCCGCTCCCAACCCTCGGGCGAAAAGGCTCGCATGG
CACCCGCGCGCGTGCCGGTA

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MLPDRPALSPERKHLQAGEALFRQDQPVRAVYPLRHGGIKRMYESALGWRQLTGFMLPGDVAGLEPNDAPQFGTSAIALQ
ASECCVVPLETAKRCEEDPAVHAALLALLHRDALRQRELLVTIGSMKAAQRLAMLLLDQAAEHRRRGTDGGEVMLAMTRN
DIASYLGLTLETVSRLLSRFASVGLITVRHRQLRIVDEKGLSDVHAEADRITLRGPDPA

Sequences:

>Translated_219_residues
MLPDRPALSPERKHLQAGEALFRQDQPVRAVYPLRHGGIKRMYESALGWRQLTGFMLPGDVAGLEPNDAPQFGTSAIALQ
ASECCVVPLETAKRCEEDPAVHAALLALLHRDALRQRELLVTIGSMKAAQRLAMLLLDQAAEHRRRGTDGGEVMLAMTRN
DIASYLGLTLETVSRLLSRFASVGLITVRHRQLRIVDEKGLSDVHAEADRITLRGPDPA
>Mature_219_residues
MLPDRPALSPERKHLQAGEALFRQDQPVRAVYPLRHGGIKRMYESALGWRQLTGFMLPGDVAGLEPNDAPQFGTSAIALQ
ASECCVVPLETAKRCEEDPAVHAALLALLHRDALRQRELLVTIGSMKAAQRLAMLLLDQAAEHRRRGTDGGEVMLAMTRN
DIASYLGLTLETVSRLLSRFASVGLITVRHRQLRIVDEKGLSDVHAEADRITLRGPDPA

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=194, Percent_Identity=30.4123711340206, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 24098; Mature: 24098

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDRPALSPERKHLQAGEALFRQDQPVRAVYPLRHGGIKRMYESALGWRQLTGFMLPGD
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHCHHHHHHHHHHCHHHHHCCCCCCC
VAGLEPNDAPQFGTSAIALQASECCVVPLETAKRCEEDPAVHAALLALLHRDALRQRELL
CCCCCCCCCCCCCCCEEEEECCCEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VTIGSMKAAQRLAMLLLDQAAEHRRRGTDGGEVMLAMTRNDIASYLGLTLETVSRLLSRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
ASVGLITVRHRQLRIVDEKGLSDVHAEADRITLRGPDPA
HHCCEEEEECCEEEEECCCCCCHHHCCCCEEEECCCCCC
>Mature Secondary Structure
MLPDRPALSPERKHLQAGEALFRQDQPVRAVYPLRHGGIKRMYESALGWRQLTGFMLPGD
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHCHHHHHHHHHHCHHHHHCCCCCCC
VAGLEPNDAPQFGTSAIALQASECCVVPLETAKRCEEDPAVHAALLALLHRDALRQRELL
CCCCCCCCCCCCCCCEEEEECCCEEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VTIGSMKAAQRLAMLLLDQAAEHRRRGTDGGEVMLAMTRNDIASYLGLTLETVSRLLSRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
ASVGLITVRHRQLRIVDEKGLSDVHAEADRITLRGPDPA
HHCCEEEEECCEEEEECCCCCCHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]