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The map label for this gene is gidA

Identifier: 94312437

GI number: 94312437

Start: 3794887

End: 3796851

Strand: Reverse

Name: gidA

Synonym: Rmet_3506

Alternate gene names: 94312437

Gene position: 3796851-3794887 (Counterclockwise)

Preceding gene: 94312438

Following gene: 94312436

Centisome position: 96.66

GC content: 62.39

Gene sequence:

>1965_bases
ATGCTTTACCCGAAAGAATTCGACGTCATAGTCGTCGGCGGTGGTCACGCCGGCACCGAAGCAGCCCTCGCCGCCGCGCG
CATGGGCTGCCAGACGCTGCTTCTGAGCCACAACATCGAAACGTTGGGGCAGATGAGCTGCAATCCGTCGATCGGTGGCA
TCGGCAAGGGTCATCTCGTCAAGGAAGTGGACGCCATGGGCGGCGCGATGGCAGCCGCCACGGACGAGGCGGGCATCCAG
TTCCGCATCCTGAACTCCAGCAAGGGCCCGGCCGTTCGGGCGACCCGTGCCCAAGCGGACCGAGTGCTGTATCGCAAGGC
CATCCGGACGCGGCTGGAGAACCAGCCAAACCTGATGCTATTCCAGCAGGCCGTGGATGATCTGATGGTGGAGGGTGACC
GCGTGGTCGGTGCTCGTACCCAGGTTGGCATCGATTTCCGCGCGCGCGCGGTGGTGCTGACGGCTGGTACCTTCCTGGAC
GGCAAGATCCACGTCGGACTCGATAACTACACGGGCGGTCGTGCGGGCGACCCTGCAGCCGTGTCGTTGTCGGCGCGTCT
CAAGGAACTGAAGCTGCCGCAAGGTCGCCTGAAGACCGGTACACCGCCGCGCATTGACGGCCGCACGATCGATTTTTCGG
TGATGGAAGAGCAGCCCGGCGACCTGGACCCGGTGCCGGTGTTTTCGTTCCTGGGCCGTCCGGAGCAACATCCGCAGCAA
CTGCCGTGCTGGATCACCCATACCAATAGCCGTACCCACGACGTCATCCGCGGCGGGCTCGATCGCTCGCCGATGTACAC
CGGTGTGATCGAAGGAGTAGGGCCGCGCTACTGCCCGAGCATCGAGGACAAGATCCATCGCTTTGCCAGCAAGGAAAGCC
ATCAGATCTTCCTGGAGCCCGAAGGGCTGACGACCAACGAGTTCTATCCGAACGGCATCTCGACGAGCCTGCCTTTCGAC
GTACAGCTTGAGCTTGTCCACTCGATTCGCGGACTGGAGAACGCGCATATCCTGCGTCCGGGCTATGCGATTGAGTATGA
CTACTTCGACCCGCGCGGGCTGAAGTCGTCGCTGGAGAGCAAGGCAATTGAGGGCTTGTTCTTCGCCGGCCAGATTAATG
GCACGACCGGCTATGAGGAAGCGGCAGCACAGGGTCTGCTGGCCGGGATAAACGCCGGTTGCTACGTACGCGAACGCGAC
GCCTGGACGCCGCGCCGCGACCAGGCATATCTCGGTGTGCTGGTCGATGACCTGATCACGCGAGGCGTGACCGAGCCGTA
CCGCATGTTCACCAGCCGCGCGGAGTTCCGCCTGAGCCTGCGCGAGGACAACGCGGACATGCGTCTGACCGAAATCGGTC
GTGAACTCGGTGTGGTCGACGATGTGCGCTGGGATGCTTTCAATCGGAAGCGCGACGCTGTTTCACGTGAAACAGAGCGA
CTCAAGAGCACCTGGGTCAATCCGACCTTGTTGCCTGAAGCAGATGCCGTTCCGCTGCTCGGTAAGGGCATCGAGCGCGA
ATACTCGCTCGCAGATCTGCTGCGTCGTCCCGAAGTCCGTTATGAGGCGCTTGTCGCGCTGCAGGATGGCCGTTTTGCAC
CAGAGACGCCGCTCGCCGATGACACGATGCTTGCCGAGCAGATTCGCGAGCAGATCGAGATCGGTATCAAGTACCACGGC
TATATCGCACGCCAGGCTGCCGAAGTAGACAAACTCGAAGCCAACGAGTCGACCAAGTTGCCGCCGAACTTCGACTATAC
CGAGGTGCGTGGCCTGGGCTTCGAGGTGAGCCAGAAGCTGAACCAGCATCGCCCGGAAACGCTGGGTCAGGCTTCGCGTA
TCTCCGGCGTGACGCCTGCGGCTATCTCGCTGCTGTTGGTACACCTGAAGAAGAAGGGCATGGGGCGCGCCGCGGCTCAG
ACATCGGCAACCCCGGTGGCCGGCAATGGACAGGAGGCTGCCTGA

Upstream 100 bases:

>100_bases
TTCACGTGAAACATCATGTCCGACCGAAGGCGGGGAATCGATTGCCGCTATAATTCGACATCCCGATTTTTCCCGCCCAG
CCTCCCGGAGGAGGTGTCCC

Downstream 100 bases:

>100_bases
GTGGGTGGTTCCCGACATTTCGCGGTCGACGACGCCGCGCAACGCCGCCGGCTCGAAGCCGGACTGGACGCGATCGGGCT
GGCACTGACACCAGCCCAGG

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MLYPKEFDVIVVGGGHAGTEAALAAARMGCQTLLLSHNIETLGQMSCNPSIGGIGKGHLVKEVDAMGGAMAAATDEAGIQ
FRILNSSKGPAVRATRAQADRVLYRKAIRTRLENQPNLMLFQQAVDDLMVEGDRVVGARTQVGIDFRARAVVLTAGTFLD
GKIHVGLDNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRTIDFSVMEEQPGDLDPVPVFSFLGRPEQHPQQ
LPCWITHTNSRTHDVIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEPEGLTTNEFYPNGISTSLPFD
VQLELVHSIRGLENAHILRPGYAIEYDYFDPRGLKSSLESKAIEGLFFAGQINGTTGYEEAAAQGLLAGINAGCYVRERD
AWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEIGRELGVVDDVRWDAFNRKRDAVSRETER
LKSTWVNPTLLPEADAVPLLGKGIEREYSLADLLRRPEVRYEALVALQDGRFAPETPLADDTMLAEQIREQIEIGIKYHG
YIARQAAEVDKLEANESTKLPPNFDYTEVRGLGFEVSQKLNQHRPETLGQASRISGVTPAAISLLLVHLKKKGMGRAAAQ
TSATPVAGNGQEAA

Sequences:

>Translated_654_residues
MLYPKEFDVIVVGGGHAGTEAALAAARMGCQTLLLSHNIETLGQMSCNPSIGGIGKGHLVKEVDAMGGAMAAATDEAGIQ
FRILNSSKGPAVRATRAQADRVLYRKAIRTRLENQPNLMLFQQAVDDLMVEGDRVVGARTQVGIDFRARAVVLTAGTFLD
GKIHVGLDNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRTIDFSVMEEQPGDLDPVPVFSFLGRPEQHPQQ
LPCWITHTNSRTHDVIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEPEGLTTNEFYPNGISTSLPFD
VQLELVHSIRGLENAHILRPGYAIEYDYFDPRGLKSSLESKAIEGLFFAGQINGTTGYEEAAAQGLLAGINAGCYVRERD
AWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEIGRELGVVDDVRWDAFNRKRDAVSRETER
LKSTWVNPTLLPEADAVPLLGKGIEREYSLADLLRRPEVRYEALVALQDGRFAPETPLADDTMLAEQIREQIEIGIKYHG
YIARQAAEVDKLEANESTKLPPNFDYTEVRGLGFEVSQKLNQHRPETLGQASRISGVTPAAISLLLVHLKKKGMGRAAAQ
TSATPVAGNGQEAA
>Mature_654_residues
MLYPKEFDVIVVGGGHAGTEAALAAARMGCQTLLLSHNIETLGQMSCNPSIGGIGKGHLVKEVDAMGGAMAAATDEAGIQ
FRILNSSKGPAVRATRAQADRVLYRKAIRTRLENQPNLMLFQQAVDDLMVEGDRVVGARTQVGIDFRARAVVLTAGTFLD
GKIHVGLDNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRTIDFSVMEEQPGDLDPVPVFSFLGRPEQHPQQ
LPCWITHTNSRTHDVIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEPEGLTTNEFYPNGISTSLPFD
VQLELVHSIRGLENAHILRPGYAIEYDYFDPRGLKSSLESKAIEGLFFAGQINGTTGYEEAAAQGLLAGINAGCYVRERD
AWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEIGRELGVVDDVRWDAFNRKRDAVSRETER
LKSTWVNPTLLPEADAVPLLGKGIEREYSLADLLRRPEVRYEALVALQDGRFAPETPLADDTMLAEQIREQIEIGIKYHG
YIARQAAEVDKLEANESTKLPPNFDYTEVRGLGFEVSQKLNQHRPETLGQASRISGVTPAAISLLLVHLKKKGMGRAAAQ
TSATPVAGNGQEAA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=664, Percent_Identity=43.9759036144578, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI19882217, Length=689, Percent_Identity=42.3802612481858, Blast_Score=476, Evalue=1e-134,
Organism=Homo sapiens, GI183227703, Length=704, Percent_Identity=41.4772727272727, Blast_Score=471, Evalue=1e-133,
Organism=Escherichia coli, GI2367273, Length=639, Percent_Identity=70.4225352112676, Blast_Score=913, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=643, Percent_Identity=40.5909797822706, Blast_Score=473, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6321202, Length=635, Percent_Identity=45.1968503937008, Blast_Score=503, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24658174, Length=644, Percent_Identity=45.6521739130435, Blast_Score=506, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_RALME (Q1LHJ8)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_585647.1
- ProteinModelPortal:   Q1LHJ8
- SMR:   Q1LHJ8
- STRING:   Q1LHJ8
- GeneID:   4040354
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_3506
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   Q1LHJ8
- ProtClustDB:   PRK05192
- BioCyc:   RMET266264:RMET_3506-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 71750; Mature: 71750

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPKEFDVIVVGGGHAGTEAALAAARMGCQTLLLSHNIETLGQMSCNPSIGGIGKGHLV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHH
KEVDAMGGAMAAATDEAGIQFRILNSSKGPAVRATRAQADRVLYRKAIRTRLENQPNLML
HHHHHCCCCEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEH
FQQAVDDLMVEGDRVVGARTQVGIDFRARAVVLTAGTFLDGKIHVGLDNYTGGRAGDPAA
HHHHHHHHHHCCCEEECCCEEECCCEEEEEEEEEECEEECCEEEEEECCCCCCCCCCCCE
VSLSARLKELKLPQGRLKTGTPPRIDGRTIDFSVMEEQPGDLDPVPVFSFLGRPEQHPQQ
EEHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCC
LPCWITHTNSRTHDVIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEP
CCEEEEECCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECC
EGLTTNEFYPNGISTSLPFDVQLELVHSIRGLENAHILRPGYAIEYDYFDPRGLKSSLES
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCCHHHHHHH
KAIEGLFFAGQINGTTGYEEAAAQGLLAGINAGCYVRERDAWTPRRDQAYLGVLVDDLIT
HHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH
RGVTEPYRMFTSRAEFRLSLREDNADMRLTEIGRELGVVDDVRWDAFNRKRDAVSRETER
HCCCHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LKSTWVNPTLLPEADAVPLLGKGIEREYSLADLLRRPEVRYEALVALQDGRFAPETPLAD
HHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
DTMLAEQIREQIEIGIKYHGYIARQAAEVDKLEANESTKLPPNFDYTEVRGLGFEVSQKL
HHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHH
NQHRPETLGQASRISGVTPAAISLLLVHLKKKGMGRAAAQTSATPVAGNGQEAA
HHCCCHHHCHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLYPKEFDVIVVGGGHAGTEAALAAARMGCQTLLLSHNIETLGQMSCNPSIGGIGKGHLV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHH
KEVDAMGGAMAAATDEAGIQFRILNSSKGPAVRATRAQADRVLYRKAIRTRLENQPNLML
HHHHHCCCCEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEH
FQQAVDDLMVEGDRVVGARTQVGIDFRARAVVLTAGTFLDGKIHVGLDNYTGGRAGDPAA
HHHHHHHHHHCCCEEECCCEEECCCEEEEEEEEEECEEECCEEEEEECCCCCCCCCCCCE
VSLSARLKELKLPQGRLKTGTPPRIDGRTIDFSVMEEQPGDLDPVPVFSFLGRPEQHPQQ
EEHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCC
LPCWITHTNSRTHDVIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEP
CCEEEEECCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECC
EGLTTNEFYPNGISTSLPFDVQLELVHSIRGLENAHILRPGYAIEYDYFDPRGLKSSLES
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCCHHHHHHH
KAIEGLFFAGQINGTTGYEEAAAQGLLAGINAGCYVRERDAWTPRRDQAYLGVLVDDLIT
HHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH
RGVTEPYRMFTSRAEFRLSLREDNADMRLTEIGRELGVVDDVRWDAFNRKRDAVSRETER
HCCCHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LKSTWVNPTLLPEADAVPLLGKGIEREYSLADLLRRPEVRYEALVALQDGRFAPETPLAD
HHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCC
DTMLAEQIREQIEIGIKYHGYIARQAAEVDKLEANESTKLPPNFDYTEVRGLGFEVSQKL
HHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHH
NQHRPETLGQASRISGVTPAAISLLLVHLKKKGMGRAAAQTSATPVAGNGQEAA
HHCCCHHHCHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA