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The map label for this gene is aroB [H]

Identifier: 94312197

GI number: 94312197

Start: 3540614

End: 3541720

Strand: Reverse

Name: aroB [H]

Synonym: Rmet_3266

Alternate gene names: 94312197

Gene position: 3541720-3540614 (Counterclockwise)

Preceding gene: 94312198

Following gene: 94312196

Centisome position: 90.16

GC content: 65.13

Gene sequence:

>1107_bases
ATGATCACGCTTGAAGTCGATCTCGGGACGCGTAGTTACCCGATCCACATTGGCAGCGGCCTGCTGGACCGCGCCGACCT
GCTGGCCCCGCATGTACGCGGCCAGCATGCCGTCATTGTCACCAACGAGACCGTGGGCCCGCTGTACGCGGCGCGCGTCG
AAGCTGTGCTTGCCGGCCTTGGCAAGACCGTGCGCACCGTGGTGCTGCCGGACGGCGAGCGCTTCAAGCACTGGGAAACG
CTGAACCTGATTTTCGATGCGCTGCTCCAGGCAGGGGCCGACCGCAAGACCACGCTGATCGCGCTGGGCGGCGGGGTGGT
GGGAGACATGACCGGGTTTGCCGCCGCATGCTACATGCGTGGCGTGCCGTTCGTGCAGATGCCGACCACGTTGCTGGCGC
AAGTCGATTCGTCGGTGGGCGGCAAGACCGGCATCAATCATCCGCTCGGCAAGAACATGATCGGCGCGTTCCACCAGCCC
AACGCGGTGATCGCCGACATTGACACGCTGCGCACGTTGCCCCCGCGCGAACTGGCGGCGGGCATGGCCGAGGTCATCAA
GCACGGGGCAATCGCCGACGCCGACTACTTCGCTTGGATCGAGGACCATATCGCCGGGCTGAACGCCTGCGACACCGGCC
TGATGGCCGAAGCGGTGCGACGCTCCTGCGAGATCAAGGCGTCCGTGGTGGCCCAGGACGAACGCGAAGGCGGCTTGCGC
GCGATTCTCAATTTCGGCCATACGTTTGGTCACGCGATCGAAGCTGGCATGGGCTATGGCGAATGGCTGCATGGCGAGGC
CGTGGGCTGTGGCATGGTGATGGCCGCGGACCTCTCGCATCGGCTCGGTTTTATCGACGTCGAGACGCGCGCCCGCATTC
GCACGCTGACGCAGGCGGCGATGCTGCCGGTGGTGGCGCCGGATCTGGGTATCGATCGCTATATCGAGTTGATGAAGGTG
GACAAGAAGGCCGAAGCGGGCAGCATCAAGTTCATCCTGCTGCGCAAGCTGGGTTCTGCCTTCATCACCACCGTGCCGGA
CGCGGACCTGCGCGAGACGCTGCGTCACGCGATATTGAAACCTCCCACCGAGGCCCCGGTCGCCTGA

Upstream 100 bases:

>100_bases
TTCTTATGCAACTTGAAATGGCCGGCTTTGTGTTTCCGCCCGCGGAAATCGTGCCCGAATCTGCCGAGGATGGTGGGCCG
CCGGCGCAGGACACCCATTC

Downstream 100 bases:

>100_bases
GCGAACGGTTATGCCTCGCAGCCCTGACCCTGTAACGGATAACGGATTGCCGCATGACCGCCCTGTCGACCGACCTTGAA
GCCCACCTTGCTCCGTACGC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MITLEVDLGTRSYPIHIGSGLLDRADLLAPHVRGQHAVIVTNETVGPLYAARVEAVLAGLGKTVRTVVLPDGERFKHWET
LNLIFDALLQAGADRKTTLIALGGGVVGDMTGFAAACYMRGVPFVQMPTTLLAQVDSSVGGKTGINHPLGKNMIGAFHQP
NAVIADIDTLRTLPPRELAAGMAEVIKHGAIADADYFAWIEDHIAGLNACDTGLMAEAVRRSCEIKASVVAQDEREGGLR
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDVETRARIRTLTQAAMLPVVAPDLGIDRYIELMKV
DKKAEAGSIKFILLRKLGSAFITTVPDADLRETLRHAILKPPTEAPVA

Sequences:

>Translated_368_residues
MITLEVDLGTRSYPIHIGSGLLDRADLLAPHVRGQHAVIVTNETVGPLYAARVEAVLAGLGKTVRTVVLPDGERFKHWET
LNLIFDALLQAGADRKTTLIALGGGVVGDMTGFAAACYMRGVPFVQMPTTLLAQVDSSVGGKTGINHPLGKNMIGAFHQP
NAVIADIDTLRTLPPRELAAGMAEVIKHGAIADADYFAWIEDHIAGLNACDTGLMAEAVRRSCEIKASVVAQDEREGGLR
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDVETRARIRTLTQAAMLPVVAPDLGIDRYIELMKV
DKKAEAGSIKFILLRKLGSAFITTVPDADLRETLRHAILKPPTEAPVA
>Mature_368_residues
MITLEVDLGTRSYPIHIGSGLLDRADLLAPHVRGQHAVIVTNETVGPLYAARVEAVLAGLGKTVRTVVLPDGERFKHWET
LNLIFDALLQAGADRKTTLIALGGGVVGDMTGFAAACYMRGVPFVQMPTTLLAQVDSSVGGKTGINHPLGKNMIGAFHQP
NAVIADIDTLRTLPPRELAAGMAEVIKHGAIADADYFAWIEDHIAGLNACDTGLMAEAVRRSCEIKASVVAQDEREGGLR
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDVETRARIRTLTQAAMLPVVAPDLGIDRYIELMKV
DKKAEAGSIKFILLRKLGSAFITTVPDADLRETLRHAILKPPTEAPVA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=340, Percent_Identity=56.1764705882353, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320332, Length=395, Percent_Identity=38.4810126582278, Blast_Score=218, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39318; Mature: 39318

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLEVDLGTRSYPIHIGSGLLDRADLLAPHVRGQHAVIVTNETVGPLYAARVEAVLAGL
CEEEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GKTVRTVVLPDGERFKHWETLNLIFDALLQAGADRKTTLIALGGGVVGDMTGFAAACYMR
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFVQMPTTLLAQVDSSVGGKTGINHPLGKNMIGAFHQPNAVIADIDTLRTLPPRELAA
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHCCCCHHHHHH
GMAEVIKHGAIADADYFAWIEDHIAGLNACDTGLMAEAVRRSCEIKASVVAQDEREGGLR
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDVETRARIRTLTQAA
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHH
MLPVVAPDLGIDRYIELMKVDKKAEAGSIKFILLRKLGSAFITTVPDADLRETLRHAILK
HHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHCCHHEECCCCHHHHHHHHHHHCC
PPTEAPVA
CCCCCCCC
>Mature Secondary Structure
MITLEVDLGTRSYPIHIGSGLLDRADLLAPHVRGQHAVIVTNETVGPLYAARVEAVLAGL
CEEEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GKTVRTVVLPDGERFKHWETLNLIFDALLQAGADRKTTLIALGGGVVGDMTGFAAACYMR
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFVQMPTTLLAQVDSSVGGKTGINHPLGKNMIGAFHQPNAVIADIDTLRTLPPRELAA
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHCCCCHHHHHH
GMAEVIKHGAIADADYFAWIEDHIAGLNACDTGLMAEAVRRSCEIKASVVAQDEREGGLR
HHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGMGYGEWLHGEAVGCGMVMAADLSHRLGFIDVETRARIRTLTQAA
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHH
MLPVVAPDLGIDRYIELMKVDKKAEAGSIKFILLRKLGSAFITTVPDADLRETLRHAILK
HHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHCCHHEECCCCHHHHHHHHHHHCC
PPTEAPVA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA