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The map label for this gene is mraY [H]

Identifier: 94312062

GI number: 94312062

Start: 3394476

End: 3395645

Strand: Reverse

Name: mraY [H]

Synonym: Rmet_3131

Alternate gene names: 94312062

Gene position: 3395645-3394476 (Counterclockwise)

Preceding gene: 94312063

Following gene: 94312061

Centisome position: 86.45

GC content: 62.82

Gene sequence:

>1170_bases
ATGTTATTGACACTGGCCCAGTGGCTGCAGAACGACTACAGCTTCCTGCGGGTCGTCAACTATCTGACTTTCCGCGCGGT
GATGGCCAACGTCACCGCGCTGGTGATCGGCCTGGGTTTCGGGCCGTGGGTGATTCGCCGCCTTACCGAACTGAAGATCG
GTCAGGCCGTGCGCACGATCGGCCCCCAGACGCACCTGGTGAAGGCCGGCACGCCGACCATGGGTGGCGTGCTGGTGCTG
ATCTCGATCGCGATCTCGACGTTGCTCTGGTGTGACTGGGGCAACCGCTTCATCTGGGTTGTGCTGCTCGTGACGCTGGG
CTATGGCGCGATTGGCTGGGTCGATGACTACCGCAAGGTGGTCTATCGCGATCCGCGCGGCATGTCGAGCCGCGAGAAAT
TCTTCTGGCAGACGCTGATCGGTCTGGTTGCCGCCGTGTATCTGGCGTTCTCGGTGTCCGAGGCCAGCAACGTGCGCATC
TGGAGTCTGTTCCTGAGCTGGATCGAGGGCGGCATGTTCGCCGACGTGCCGTACAAGATGAACCTGATCGTGCCCTTCTT
CAAGGAAGTGAGCTACCCGCTCGGCGTGACCGGTTTCATCGTGCTGACCTATCTGGTGATCGTTGGCTCGAGCAACGCGG
TGAACCTGACCGACGGTCTGGACGGCCTCGTGATCATGCCCGTGGTGCTGGTGGGCGGCGGCCTTGGCGTGTTTGCCTAT
GTGATGGGCAATGCGGTCTACAGCAAGTACCTGCTGTTCCCGCACATTCCCGGCGCGGGCGAGCTGCTGATCTTCTGCTC
GGCGATGGCCGGCGCGGGACTGGCGTTCCTCTGGTTCAACGCCCACCCGGCACGCGTGTTCATGGGCGACGTTGGCGCGC
TGGCGCTGGGCGGGGCGCTGGGCACGGTAGCGGTGATCGTGCGCCAGGAGATCGTGCTGTTCGTGATGGGCGGGATCTTC
GTGGTGGAAACGCTGTCAGTGATGCTCCAGGTGTCGTGGTTCAAGTTCACGAAGCGTCGCTACGGCGAAGGCCGCCGGCT
GTTCCGCATGGCGCCGCTGCATCACCACTTCGAACTGGGCGGCTGGAAGGAAACACAAGTGACGGTGCGCTTCTGGATCA
TCACGATGCTGCTGGTGCTGATCGGGTTGTCGTCGCTGAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
AGCGGCCGTGCTGGTGAAGGGATCGCGCTTCATGCGCATGGAACGGATGGTCGATGCGCTTGTCGCATCACCTTCCGCTC
ATTAACGAAACAGACCAACG

Downstream 100 bases:

>100_bases
ACCCGGGCTGAAATTTTTAATCTACGGACTCTACAAGGCAGGAAAACGAAGTGTTTGGCGTGTTGCAGAAACCTCATGTG
CTGGTACTTGGCCTCGGTGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLTLAQWLQNDYSFLRVVNYLTFRAVMANVTALVIGLGFGPWVIRRLTELKIGQAVRTIGPQTHLVKAGTPTMGGVLVL
ISIAISTLLWCDWGNRFIWVVLLVTLGYGAIGWVDDYRKVVYRDPRGMSSREKFFWQTLIGLVAAVYLAFSVSEASNVRI
WSLFLSWIEGGMFADVPYKMNLIVPFFKEVSYPLGVTGFIVLTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGGGLGVFAY
VMGNAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPARVFMGDVGALALGGALGTVAVIVRQEIVLFVMGGIF
VVETLSVMLQVSWFKFTKRRYGEGRRLFRMAPLHHHFELGGWKETQVTVRFWIITMLLVLIGLSSLKLR

Sequences:

>Translated_389_residues
MLLTLAQWLQNDYSFLRVVNYLTFRAVMANVTALVIGLGFGPWVIRRLTELKIGQAVRTIGPQTHLVKAGTPTMGGVLVL
ISIAISTLLWCDWGNRFIWVVLLVTLGYGAIGWVDDYRKVVYRDPRGMSSREKFFWQTLIGLVAAVYLAFSVSEASNVRI
WSLFLSWIEGGMFADVPYKMNLIVPFFKEVSYPLGVTGFIVLTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGGGLGVFAY
VMGNAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPARVFMGDVGALALGGALGTVAVIVRQEIVLFVMGGIF
VVETLSVMLQVSWFKFTKRRYGEGRRLFRMAPLHHHFELGGWKETQVTVRFWIITMLLVLIGLSSLKLR
>Mature_389_residues
MLLTLAQWLQNDYSFLRVVNYLTFRAVMANVTALVIGLGFGPWVIRRLTELKIGQAVRTIGPQTHLVKAGTPTMGGVLVL
ISIAISTLLWCDWGNRFIWVVLLVTLGYGAIGWVDDYRKVVYRDPRGMSSREKFFWQTLIGLVAAVYLAFSVSEASNVRI
WSLFLSWIEGGMFADVPYKMNLIVPFFKEVSYPLGVTGFIVLTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGGGLGVFAY
VMGNAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPARVFMGDVGALALGGALGTVAVIVRQEIVLFVMGGIF
VVETLSVMLQVSWFKFTKRRYGEGRRLFRMAPLHHHFELGGWKETQVTVRFWIITMLLVLIGLSSLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=391, Percent_Identity=52.1739130434783, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 43061; Mature: 43061

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure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CCCCHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA