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The map label for this gene is pabB [H]

Identifier: 94311852

GI number: 94311852

Start: 3173288

End: 3175201

Strand: Reverse

Name: pabB [H]

Synonym: Rmet_2920

Alternate gene names: 94311852

Gene position: 3175201-3173288 (Counterclockwise)

Preceding gene: 94311853

Following gene: 94311843

Centisome position: 80.83

GC content: 66.35

Gene sequence:

>1914_bases
ATGCCCAACGCAGCGATAATGCCGACTGCAGCGTTTTCGCATCCAGTCTTCGTGGTACCCATCCCTTCGCCCCCCTTCGT
TCTGCTCGACGACGCCACAGCCGGCTCTGGCGTGACGGCTTCGCGCCTCTATACCGATTTCGTCCGGGAGGACGTGCTGG
CGGCCGGTGCCGACGTATCGGCGCTTGACACGCTGCTGGCCAGCGGTTGGCGGGACGGGTTGCACGCCACGTTCTTTGCG
CCCTACGAATTCGGTGGTGCGATCGTTGGCGCACCCGTGCACGTTGGCGATGCGCTGCCGTTTCACGACGGCGCCCTGCG
CGTGCTGTGGTTTCGCACGTTGCGCCGGCTCGATACGGAAGGTGTGGCGCAGTGGCTAGCCGCAGGCGCACAACCAGGCC
CGACGGGCGCGCTCGACGTGACGGCCAGCACCACGCGGACGCAATACACCGAAGCGATCGCGCGTATCCACGATTACATC
GAGGCGGGCGATACCTATCAGGTTAACTTCACGCAACGACTACGCTGTCGCGTGTTTGGCGATCCGATGGCGTTCTATGC
GGCGTTGCGCGCGGCACAGCCGGTGCCGTTCGGCGTGCTTGCGCATCTGCCCGGTGGCGGTTGGGTGCTGTCGCTATCGC
CCGAACTGTTCGTCGAGCACGATGGCCACGGACATCTCGTCGCACGTCCAATGAAGGGCACCGCGCCGCGCTCAGGGGAT
GCCGAACAGGATGCGCGCGCCGCGAAACGACTGGCCACCGATGCCAAGAACCGCGCCGAGAACGTGATGATCGTCGACCT
GCTGCGCAACGACCTCGGTCGCGTGGCGATCCCCGGGAGCGTGGCGGTGCCCGAGCGCTTCGTCGTCGAACCGTTCGGTC
GCGTGTTGCAAATGACGTCGACAGTCACCGCGACCGCGCGCCCGGGTACGTCGTTCGGTGCGTTGATGGCCGCGCTGTTC
CCGTGCGGCTCGATTACCGGCGCGCCCAAGCGGCGCACGATGCAGATCATCGCCGAGCTCGAGACGTCGCCACGTGGGTT
GTACACGGGCGCGATCGGTTGGCTCGATGCGACATCGCATAAGACTACGGAGGTCATAGGCGTCGGCGCCTTCGGCATGT
CTGTGGCAATCCGCACGCTGGTGCTGGCGCCGCCCGGGGCCGATGGCCTGCGCGCGGCCGAGATGGGCGTGGGCGGTGGC
ATCGTGCACGACAGCGTGGCCGACGATGAGTACGCCGAATGCGGATGGAAAGCGCGGTTCCTGATCGGTCATGACCCCGG
CTTCACGTTGTTCGAGACCATGCATGCGCGCGATGGCGCAGTGCTACATCGCGAGCGCCATTTGCAGCGACTAGCGAACT
CGTCGGCGGCGTTCGGCTTCGCGCTGGACTTGCCTGAAGCCCGCGCGGCGGTGCAGGCTGAAGCCGCGCGACTGGGCGAT
GGCGACTGGCGCCTGCGCGTGAGTGTGGACAAGCGCGGCACGCTGGTATTTGCCAGCGGGGCATTGGCTCCGCTCGCGCA
TGGCGTCGTGGGGCTCGAGATCGCACCGACATGCCTGCCCGTTCACGATCCGCTGCGCCGGCACAAGCTCAGCGCGCGCG
CCGTGTTCGATCAGGGATGGCAGGCCGCGGAGCGGGCAGGCGGGTTCGATAGCCTGTTCTTCAACACGTGCGACGAACTG
CTCGAAGGCGGCCGCAGTTCGGTGTTCATCAAGGTAGATGGTCATTGGATGACACCGCCACTCTCGGCGGACATCCTGCC
GGGCGTGATGCGTGCCGTGGTGCTCGAAGAAGGGGACGCATTGATCGACGGACCGGTGCAGGAAGCCACCGTGACGCGTG
ACATGGTGCAACGCGCCGAAGCCATCGTTATCGCCAACGCATTGCGCGGCACGCTGCGCGCGCGCCTGATCTGA

Upstream 100 bases:

>100_bases
CCTGGCTCGACAAGGTGAAGAGCTTCTTTAGCTGATCGCCTTATCGACTCGTCGACAGGACGATGAAACCGGCCACGTGT
CCAGCGTGGCCGGTTTTTTT

Downstream 100 bases:

>100_bases
GCAACGTGTCTAGGGTGTCTGCCGCAGCGACTACTTGTGTCGCGTATCAAGCCGGCCTTCGCCGAGCTTCCAGCGCACCA
CGCCGGGCAGGTTGATCAGC

Product: Anthranilate/para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MPNAAIMPTAAFSHPVFVVPIPSPPFVLLDDATAGSGVTASRLYTDFVREDVLAAGADVSALDTLLASGWRDGLHATFFA
PYEFGGAIVGAPVHVGDALPFHDGALRVLWFRTLRRLDTEGVAQWLAAGAQPGPTGALDVTASTTRTQYTEAIARIHDYI
EAGDTYQVNFTQRLRCRVFGDPMAFYAALRAAQPVPFGVLAHLPGGGWVLSLSPELFVEHDGHGHLVARPMKGTAPRSGD
AEQDARAAKRLATDAKNRAENVMIVDLLRNDLGRVAIPGSVAVPERFVVEPFGRVLQMTSTVTATARPGTSFGALMAALF
PCGSITGAPKRRTMQIIAELETSPRGLYTGAIGWLDATSHKTTEVIGVGAFGMSVAIRTLVLAPPGADGLRAAEMGVGGG
IVHDSVADDEYAECGWKARFLIGHDPGFTLFETMHARDGAVLHRERHLQRLANSSAAFGFALDLPEARAAVQAEAARLGD
GDWRLRVSVDKRGTLVFASGALAPLAHGVVGLEIAPTCLPVHDPLRRHKLSARAVFDQGWQAAERAGGFDSLFFNTCDEL
LEGGRSSVFIKVDGHWMTPPLSADILPGVMRAVVLEEGDALIDGPVQEATVTRDMVQRAEAIVIANALRGTLRARLI

Sequences:

>Translated_637_residues
MPNAAIMPTAAFSHPVFVVPIPSPPFVLLDDATAGSGVTASRLYTDFVREDVLAAGADVSALDTLLASGWRDGLHATFFA
PYEFGGAIVGAPVHVGDALPFHDGALRVLWFRTLRRLDTEGVAQWLAAGAQPGPTGALDVTASTTRTQYTEAIARIHDYI
EAGDTYQVNFTQRLRCRVFGDPMAFYAALRAAQPVPFGVLAHLPGGGWVLSLSPELFVEHDGHGHLVARPMKGTAPRSGD
AEQDARAAKRLATDAKNRAENVMIVDLLRNDLGRVAIPGSVAVPERFVVEPFGRVLQMTSTVTATARPGTSFGALMAALF
PCGSITGAPKRRTMQIIAELETSPRGLYTGAIGWLDATSHKTTEVIGVGAFGMSVAIRTLVLAPPGADGLRAAEMGVGGG
IVHDSVADDEYAECGWKARFLIGHDPGFTLFETMHARDGAVLHRERHLQRLANSSAAFGFALDLPEARAAVQAEAARLGD
GDWRLRVSVDKRGTLVFASGALAPLAHGVVGLEIAPTCLPVHDPLRRHKLSARAVFDQGWQAAERAGGFDSLFFNTCDEL
LEGGRSSVFIKVDGHWMTPPLSADILPGVMRAVVLEEGDALIDGPVQEATVTRDMVQRAEAIVIANALRGTLRARLI
>Mature_636_residues
PNAAIMPTAAFSHPVFVVPIPSPPFVLLDDATAGSGVTASRLYTDFVREDVLAAGADVSALDTLLASGWRDGLHATFFAP
YEFGGAIVGAPVHVGDALPFHDGALRVLWFRTLRRLDTEGVAQWLAAGAQPGPTGALDVTASTTRTQYTEAIARIHDYIE
AGDTYQVNFTQRLRCRVFGDPMAFYAALRAAQPVPFGVLAHLPGGGWVLSLSPELFVEHDGHGHLVARPMKGTAPRSGDA
EQDARAAKRLATDAKNRAENVMIVDLLRNDLGRVAIPGSVAVPERFVVEPFGRVLQMTSTVTATARPGTSFGALMAALFP
CGSITGAPKRRTMQIIAELETSPRGLYTGAIGWLDATSHKTTEVIGVGAFGMSVAIRTLVLAPPGADGLRAAEMGVGGGI
VHDSVADDEYAECGWKARFLIGHDPGFTLFETMHARDGAVLHRERHLQRLANSSAAFGFALDLPEARAAVQAEAARLGDG
DWRLRVSVDKRGTLVFASGALAPLAHGVVGLEIAPTCLPVHDPLRRHKLSARAVFDQGWQAAERAGGFDSLFFNTCDELL
EGGRSSVFIKVDGHWMTPPLSADILPGVMRAVVLEEGDALIDGPVQEATVTRDMVQRAEAIVIANALRGTLRARLI

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=292, Percent_Identity=42.8082191780822, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1787518, Length=308, Percent_Identity=29.5454545454545, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786809, Length=169, Percent_Identity=27.810650887574, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=271, Percent_Identity=33.210332103321, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324361, Length=295, Percent_Identity=28.4745762711864, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 67781; Mature: 67650

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNAAIMPTAAFSHPVFVVPIPSPPFVLLDDATAGSGVTASRLYTDFVREDVLAAGADVS
CCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHH
ALDTLLASGWRDGLHATFFAPYEFGGAIVGAPVHVGDALPFHDGALRVLWFRTLRRLDTE
HHHHHHHHCCCCCCCEEEECCHHCCCEEEECCEECCCCCCCCCCHHHHHHHHHHHHCCHH
GVAQWLAAGAQPGPTGALDVTASTTRTQYTEAIARIHDYIEAGDTYQVNFTQRLRCRVFG
HHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEHHEEEEEEEEC
DPMAFYAALRAAQPVPFGVLAHLPGGGWVLSLSPELFVEHDGHGHLVARPMKGTAPRSGD
CHHHHHHHHHHCCCCCCHHEEECCCCCEEEEECCEEEEEECCCCCEEEECCCCCCCCCCC
AEQDARAAKRLATDAKNRAENVMIVDLLRNDLGRVAIPGSVAVPERFVVEPFGRVLQMTS
CHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
TVTATARPGTSFGALMAALFPCGSITGAPKRRTMQIIAELETSPRGLYTGAIGWLDATSH
HEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCEEEEECCCC
KTTEVIGVGAFGMSVAIRTLVLAPPGADGLRAAEMGVGGGIVHDSVADDEYAECGWKARF
CCEEEEEECHHHHHHHHHEEEECCCCCCCCCHHHCCCCCCEECCCCCCCHHHHCCCEEEE
LIGHDPGFTLFETMHARDGAVLHRERHLQRLANSSAAFGFALDLPEARAAVQAEAARLGD
EEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCC
GDWRLRVSVDKRGTLVFASGALAPLAHGVVGLEIAPTCLPVHDPLRRHKLSARAVFDQGW
CCEEEEEEECCCCEEEEECCCHHHHHCCEEEEEECCCEECCCCHHHHHHHHHHHHHHCCH
QAAERAGGFDSLFFNTCDELLEGGRSSVFIKVDGHWMTPPLSADILPGVMRAVVLEEGDA
HHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHHHHHCCCC
LIDGPVQEATVTRDMVQRAEAIVIANALRGTLRARLI
EECCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
PNAAIMPTAAFSHPVFVVPIPSPPFVLLDDATAGSGVTASRLYTDFVREDVLAAGADVS
CCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHH
ALDTLLASGWRDGLHATFFAPYEFGGAIVGAPVHVGDALPFHDGALRVLWFRTLRRLDTE
HHHHHHHHCCCCCCCEEEECCHHCCCEEEECCEECCCCCCCCCCHHHHHHHHHHHHCCHH
GVAQWLAAGAQPGPTGALDVTASTTRTQYTEAIARIHDYIEAGDTYQVNFTQRLRCRVFG
HHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEHHEEEEEEEEC
DPMAFYAALRAAQPVPFGVLAHLPGGGWVLSLSPELFVEHDGHGHLVARPMKGTAPRSGD
CHHHHHHHHHHCCCCCCHHEEECCCCCEEEEECCEEEEEECCCCCEEEECCCCCCCCCCC
AEQDARAAKRLATDAKNRAENVMIVDLLRNDLGRVAIPGSVAVPERFVVEPFGRVLQMTS
CHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
TVTATARPGTSFGALMAALFPCGSITGAPKRRTMQIIAELETSPRGLYTGAIGWLDATSH
HEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCEEEEECCCC
KTTEVIGVGAFGMSVAIRTLVLAPPGADGLRAAEMGVGGGIVHDSVADDEYAECGWKARF
CCEEEEEECHHHHHHHHHEEEECCCCCCCCCHHHCCCCCCEECCCCCCCHHHHCCCEEEE
LIGHDPGFTLFETMHARDGAVLHRERHLQRLANSSAAFGFALDLPEARAAVQAEAARLGD
EEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCC
GDWRLRVSVDKRGTLVFASGALAPLAHGVVGLEIAPTCLPVHDPLRRHKLSARAVFDQGW
CCEEEEEEECCCCEEEEECCCHHHHHCCEEEEEECCCEECCCCHHHHHHHHHHHHHHCCH
QAAERAGGFDSLFFNTCDELLEGGRSSVFIKVDGHWMTPPLSADILPGVMRAVVLEEGDA
HHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCHHHHHHHHHHHHHHCCCC
LIDGPVQEATVTRDMVQRAEAIVIANALRGTLRARLI
EECCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]