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The map label for this gene is argF [H]

Identifier: 94311834

GI number: 94311834

Start: 3156091

End: 3157014

Strand: Reverse

Name: argF [H]

Synonym: Rmet_2902

Alternate gene names: 94311834

Gene position: 3157014-3156091 (Counterclockwise)

Preceding gene: 94311836

Following gene: 94311833

Centisome position: 80.37

GC content: 62.66

Gene sequence:

>924_bases
ATGAGCCCAACCCCGATCAAGCATTACCTCCAGTTCAGCGATCTCAGTGCCGACGAGTACGAGTACCTGCTGGACCGCGC
GCGGATCCTCAAGGCGAAGTTCAAGAACTACGAAACGTGGCACCCGTTGCATGACCGCACGCTGGCCATGATCTTCGAGA
AGAATTCCACGCGCACGCGCCTGTCGTTCGAAGCCGGCATCCACCAGCTCGGCGGTCACGCGGTGTTCCTGAACACCCGC
GATTCGCAACTGGGCCGTGGCGAGCCGATCGAGGATGCCGCCCAGGTGATCTCGCGCATGGTCGACATCATCATGATCCG
CACGTTCGGACAGGAAATCATCGACCGCTTCGCCAAGCACTCGCGCGTGCCGGTGATCAACGGGCTCACCAACGAATACC
ACCCGTGCCAGGTACTGGCCGACGTGTTCACGTACATCGAACAGCGCGGCACCATCGCCGGCAAGACCGTGGCGTGGATC
GGCGATGCCAACAACATGGCCTACACCTGGATCCAGGCCGCCGAGCGCCTTGATTTCACGTTCCATTTCTCGGCGCCTCC
GGGCTATCAGCTCGATCCGGCGATGGTGCCGGACTGGGCCGCATCGCGCGTGAAGGTGTTCGATAATCCGCTCGACGCCT
GCCAGGGCGCGCATCTGGTCACCACCGATGTGTGGACCAGCATGGGCTTCGAGGCCGAGAACGATGCGCGCAAGCGTGCA
TTCAAGGATTGGATGGTGACGACCGCGATGATGGATCGCGCCGCGGACGACGCCCTGTTCATGCACTGCCTGCCCGCGCA
CCGTGGCGAGGAAGTGGAAGCGGCGGTGATCGACGGCCCGCGTAGCGTGGTGTGGGAAGAAGCCGAGAACCGTCTGCACG
TGCAGAAGGCGCTGATGGAATACCTGCTCTGCGGCCGCTACTAA

Upstream 100 bases:

>100_bases
AGCGACGCGAAAGGCGGCTCCGCGACACGCTCTGGCCCTGAAGGATCGCCCAGTCTGGCGTCCGGGCCACGTGTCCAAAC
CGAGCCGCCTTATTTGTTTT

Downstream 100 bases:

>100_bases
GCGCCTGCCGGAGCTGATCAAAGGGGGCCGTCCAGGCTCCCTTTTTTACGCCCACCGATTTAATAATGAAACCCGAAGAC
TCGAGGAGATTGAGATGAGC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSPTPIKHYLQFSDLSADEYEYLLDRARILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNTR
DSQLGRGEPIEDAAQVISRMVDIIMIRTFGQEIIDRFAKHSRVPVINGLTNEYHPCQVLADVFTYIEQRGTIAGKTVAWI
GDANNMAYTWIQAAERLDFTFHFSAPPGYQLDPAMVPDWAASRVKVFDNPLDACQGAHLVTTDVWTSMGFEAENDARKRA
FKDWMVTTAMMDRAADDALFMHCLPAHRGEEVEAAVIDGPRSVVWEEAENRLHVQKALMEYLLCGRY

Sequences:

>Translated_307_residues
MSPTPIKHYLQFSDLSADEYEYLLDRARILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNTR
DSQLGRGEPIEDAAQVISRMVDIIMIRTFGQEIIDRFAKHSRVPVINGLTNEYHPCQVLADVFTYIEQRGTIAGKTVAWI
GDANNMAYTWIQAAERLDFTFHFSAPPGYQLDPAMVPDWAASRVKVFDNPLDACQGAHLVTTDVWTSMGFEAENDARKRA
FKDWMVTTAMMDRAADDALFMHCLPAHRGEEVEAAVIDGPRSVVWEEAENRLHVQKALMEYLLCGRY
>Mature_306_residues
SPTPIKHYLQFSDLSADEYEYLLDRARILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNTRD
SQLGRGEPIEDAAQVISRMVDIIMIRTFGQEIIDRFAKHSRVPVINGLTNEYHPCQVLADVFTYIEQRGTIAGKTVAWIG
DANNMAYTWIQAAERLDFTFHFSAPPGYQLDPAMVPDWAASRVKVFDNPLDACQGAHLVTTDVWTSMGFEAENDARKRAF
KDWMVTTAMMDRAADDALFMHCLPAHRGEEVEAAVIDGPRSVVWEEAENRLHVQKALMEYLLCGRY

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=302, Percent_Identity=38.4105960264901, Blast_Score=217, Evalue=9e-57,
Organism=Homo sapiens, GI18105007, Length=308, Percent_Identity=27.5974025974026, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=35.3846153846154, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=34.7432024169184, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI2367364, Length=204, Percent_Identity=36.2745098039216, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193204318, Length=292, Percent_Identity=28.0821917808219, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322373, Length=313, Percent_Identity=34.8242811501597, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322331, Length=306, Percent_Identity=25.4901960784314, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=26.8608414239482, Blast_Score=104, Evalue=8e-23,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35015; Mature: 34884

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTPIKHYLQFSDLSADEYEYLLDRARILKAKFKNYETWHPLHDRTLAMIFEKNSTRTR
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIHQLGGHAVFLNTRDSQLGRGEPIEDAAQVISRMVDIIMIRTFGQEIIDRFAKH
EEHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SRVPVINGLTNEYHPCQVLADVFTYIEQRGTIAGKTVAWIGDANNMAYTWIQAAERLDFT
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEE
FHFSAPPGYQLDPAMVPDWAASRVKVFDNPLDACQGAHLVTTDVWTSMGFEAENDARKRA
EEECCCCCCCCCCCCCCCHHCCHHEECCCHHHHHCCCEEEEHHHHHHCCCCCCCHHHHHH
FKDWMVTTAMMDRAADDALFMHCLPAHRGEEVEAAVIDGPRSVVWEEAENRLHVQKALME
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
YLLCGRY
HHHHCCC
>Mature Secondary Structure 
SPTPIKHYLQFSDLSADEYEYLLDRARILKAKFKNYETWHPLHDRTLAMIFEKNSTRTR
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIHQLGGHAVFLNTRDSQLGRGEPIEDAAQVISRMVDIIMIRTFGQEIIDRFAKH
EEHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SRVPVINGLTNEYHPCQVLADVFTYIEQRGTIAGKTVAWIGDANNMAYTWIQAAERLDFT
CCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEE
FHFSAPPGYQLDPAMVPDWAASRVKVFDNPLDACQGAHLVTTDVWTSMGFEAENDARKRA
EEECCCCCCCCCCCCCCCHHCCHHEECCCHHHHHCCCEEEEHHHHHHCCCCCCCHHHHHH
FKDWMVTTAMMDRAADDALFMHCLPAHRGEEVEAAVIDGPRSVVWEEAENRLHVQKALME
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
YLLCGRY
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA