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The map label for this gene is murB [H]

Identifier: 94311832

GI number: 94311832

Start: 3154617

End: 3155627

Strand: Direct

Name: murB [H]

Synonym: Rmet_2900

Alternate gene names: 94311832

Gene position: 3154617-3155627 (Clockwise)

Preceding gene: 94311830

Following gene: 335055636

Centisome position: 80.31

GC content: 64.49

Gene sequence:

>1011_bases
ATGGCAGATTTCCTCGAATTCTATCCCCTGCGCACCCACAATACATTCGGGTTCGATGCGCGCGCGCGCCTAGCCGTCCA
TATTCGCAACGAATCGGACCTGGTTTCGGCCCTGTCCGACCATCGGATCGACAATCTGCCCATCGTCGTGCTCGGTGGCG
GCAGCAATGTGGTACTGACCGGCGATCTCGATGCATGTGTGCTGCTGATGGAGATCCCCGGGTACGACGTGGCGGAGGAT
GATGCCAGCTGGCTCGTCACGGCCGGCGCCGGGGAAACCTGGCACGGGCTGGTAAACCGCACGATCGACGAAGGGATGCC
TGGCCTGGAAAACCTGGCGCTGATCCCGGGCACGGCCGGCGCCGCCCCGATCCAGAACATTGGCGCATACGGCGTGGAGT
TGCGCGAACGTTTCGCCCGGCTACGTGCCTATGACCGGCAATCCGGCGACTTCGTCACGATCGACCTGGACACATGCGCG
TTCGGCTACCGGGACAGCCTGTTCAAGCGCGAAGGCCGCGACCGCTACATCATCACGGCGGTCACACTGCGGCTGCCCAA
GGCCTGGCAACCGGTACTGAACTACGGCGAGCTGACGCGTGAACTGGAAGGTGTGAGCACGCCCGATGCAGCGCAAGTCC
GCGACGCGATCGTTGCGATCCGCTCGCGCAAGCTGCCGGATCCGGCAAAGATCGGCAACGCCGGGAGCTTCTTCAAGAAT
CCGGTCGTCGACGCCTCGCTGCGCAATGCCCTGCTGGCCGACCACCCTGCCCTCGTCAGCTATCCGCAACCCGATGGCAG
CTACAAGCTGGCCGCAGGCTGGTTGATCGACCAGTGTGGATTCAAGGGTGTCGACGACGGCCCGGTGGGCGTCTACGGCA
AGCAAGCACTGGTGCTGGTGCACCACGGCGGTGGAACTGGGGCGGCGCTGCTAGCGCTGGCTAACCGCATCGCAGACGCG
GTGCAGGCGCACTTCGGGGTCCGGATCGAGCCGGAACCGGTGATTCTGTAG

Upstream 100 bases:

>100_bases
TTAGCGGCGGCCGGTCCGTAACGGTTACGTATAATCGGGCCTGCCTCTCAGTCCGGGGAGGCCATTTCGCCGCTTCGGCG
CCCGCTTTTCCCGTCCTTGC

Downstream 100 bases:

>100_bases
AGGGTGTCTTGCTCCCCTCTCCCACGTTGTGGAAGAGGGGTAAATTCTCGGTACGGCTTAACCGAAGTGGCAGACGTAAT
CCAGGGTCTCGGTCACTTCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MADFLEFYPLRTHNTFGFDARARLAVHIRNESDLVSALSDHRIDNLPIVVLGGGSNVVLTGDLDACVLLMEIPGYDVAED
DASWLVTAGAGETWHGLVNRTIDEGMPGLENLALIPGTAGAAPIQNIGAYGVELRERFARLRAYDRQSGDFVTIDLDTCA
FGYRDSLFKREGRDRYIITAVTLRLPKAWQPVLNYGELTRELEGVSTPDAAQVRDAIVAIRSRKLPDPAKIGNAGSFFKN
PVVDASLRNALLADHPALVSYPQPDGSYKLAAGWLIDQCGFKGVDDGPVGVYGKQALVLVHHGGGTGAALLALANRIADA
VQAHFGVRIEPEPVIL

Sequences:

>Translated_336_residues
MADFLEFYPLRTHNTFGFDARARLAVHIRNESDLVSALSDHRIDNLPIVVLGGGSNVVLTGDLDACVLLMEIPGYDVAED
DASWLVTAGAGETWHGLVNRTIDEGMPGLENLALIPGTAGAAPIQNIGAYGVELRERFARLRAYDRQSGDFVTIDLDTCA
FGYRDSLFKREGRDRYIITAVTLRLPKAWQPVLNYGELTRELEGVSTPDAAQVRDAIVAIRSRKLPDPAKIGNAGSFFKN
PVVDASLRNALLADHPALVSYPQPDGSYKLAAGWLIDQCGFKGVDDGPVGVYGKQALVLVHHGGGTGAALLALANRIADA
VQAHFGVRIEPEPVIL
>Mature_335_residues
ADFLEFYPLRTHNTFGFDARARLAVHIRNESDLVSALSDHRIDNLPIVVLGGGSNVVLTGDLDACVLLMEIPGYDVAEDD
ASWLVTAGAGETWHGLVNRTIDEGMPGLENLALIPGTAGAAPIQNIGAYGVELRERFARLRAYDRQSGDFVTIDLDTCAF
GYRDSLFKREGRDRYIITAVTLRLPKAWQPVLNYGELTRELEGVSTPDAAQVRDAIVAIRSRKLPDPAKIGNAGSFFKNP
VVDASLRNALLADHPALVSYPQPDGSYKLAAGWLIDQCGFKGVDDGPVGVYGKQALVLVHHGGGTGAALLALANRIADAV
QAHFGVRIEPEPVIL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=325, Percent_Identity=47.3846153846154, Blast_Score=298, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 36209; Mature: 36077

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFLEFYPLRTHNTFGFDARARLAVHIRNESDLVSALSDHRIDNLPIVVLGGGSNVVLT
CCCCHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCEEEE
GDLDACVLLMEIPGYDVAEDDASWLVTAGAGETWHGLVNRTIDEGMPGLENLALIPGTAG
CCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHCEEEECCCCC
AAPIQNIGAYGVELRERFARLRAYDRQSGDFVTIDLDTCAFGYRDSLFKREGRDRYIITA
CCCHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCHHHHHHHHCCCCEEEEEE
VTLRLPKAWQPVLNYGELTRELEGVSTPDAAQVRDAIVAIRSRKLPDPAKIGNAGSFFKN
EEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCHHCC
PVVDASLRNALLADHPALVSYPQPDGSYKLAAGWLIDQCGFKGVDDGPVGVYGKQALVLV
CCCCHHHHHHHHCCCCCEEECCCCCCCEEEEECEEEHHCCCCCCCCCCCCEECCEEEEEE
HHGGGTGAALLALANRIADAVQAHFGVRIEPEPVIL
ECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
ADFLEFYPLRTHNTFGFDARARLAVHIRNESDLVSALSDHRIDNLPIVVLGGGSNVVLT
CCCHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCEEEEECCCCEEEE
GDLDACVLLMEIPGYDVAEDDASWLVTAGAGETWHGLVNRTIDEGMPGLENLALIPGTAG
CCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHCEEEECCCCC
AAPIQNIGAYGVELRERFARLRAYDRQSGDFVTIDLDTCAFGYRDSLFKREGRDRYIITA
CCCHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCHHHHHHHHCCCCEEEEEE
VTLRLPKAWQPVLNYGELTRELEGVSTPDAAQVRDAIVAIRSRKLPDPAKIGNAGSFFKN
EEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCHHCC
PVVDASLRNALLADHPALVSYPQPDGSYKLAAGWLIDQCGFKGVDDGPVGVYGKQALVLV
CCCCHHHHHHHHCCCCCEEECCCCCCCEEEEECEEEHHCCCCCCCCCCCCEECCEEEEEE
HHGGGTGAALLALANRIADAVQAHFGVRIEPEPVIL
ECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA