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The map label for this gene is hutI

Identifier: 94311784

GI number: 94311784

Start: 3100475

End: 3101722

Strand: Reverse

Name: hutI

Synonym: Rmet_2852

Alternate gene names: 94311784

Gene position: 3101722-3100475 (Counterclockwise)

Preceding gene: 94311785

Following gene: 94311783

Centisome position: 78.96

GC content: 68.19

Gene sequence:

>1248_bases
ATGAAATTCAACGAAGCGCCGTCAGCCGACGGCGTCTGGCATCACTGCCATCTGCTGCCCGCCGCCGATCCGGCGCAGGC
GATTCGTGATGGCGCCATCGTCGTCGAGCAGGGCCGCATCGCATGGCTCGGCGCATTCGCCGCGCTGCCCGACGTATATC
GCCATTTGCCGCGGCACGACGCCAACGGCGCGTGGATCACGCCAGGACTGGTCGATTGCCATACCCATCTGGTCTATGGC
GGGCAGCGTGCCGACGAGTTCGCGATGCGGCTGGCCGGCGCAAGCTACGAAGAGATTGCGCGCGCGGGAGGCGGCATTGT
GTCCACGGTGCGCGCCACGCGCGAGGCGGACGAAGCCACGCTGTTCGCGCAGGCGTCCGCGCGGCTCGAGCCGCTGCTCG
CGGAAGGCGTGACCGCGATCGAGATCAAGTCGGGCTATGGCCTGTCGCTGGAAGCTGAACGCAAGCAGTTGCGTGTGGCG
CGCCAGCTTGGCGAGACCTATGGCGTCGCCGTCCATACGACGTTCCTTGGCGCTCATGCGCTGCCACCCGAGTACGCCGG
CCGCGCCGACGCGTACATCGAGCTGGTCTGCGAGACGATGCTGCCGGCGCTGGCTGCGGAAGGGCTTGTCGATGCGGTCG
ACGCGTTCTGTGAGGGCATTGGCTTCTCGATCGCGCAGACCACGCGCGTGTTCGAGGCCGCCGCGCGCCACGGCCTGCCG
GTCAAGCTCCATGCCGAGCAACTGAGCAACCTGGGCGGCGCGGCGCTGGCAGCGCGCCACAAGGCGATCTCGGCCGATCA
CCTCGAGCATCTCGACGAGGCCGGTGTGGTGGCGATGGCCGAAGCGGGTACCGTGGCCGTGCTCCTGCCCGGGGCGTACT
ATTTCCTGCGTGATACGCAACTGCCGCCGCTGGCGCTGCTGCGCAAGCATGGCGTGCCGATGGCGATCTCGACCGATCAC
AATCCAGGTACGTCGCCCACCACCTCGCTGCTGCTGATGATGAACATGGGCTGCACGATATTCCGCATGACGGTGCCCGA
GGTGCTGGCCGGTGTGACGACACACGCGGCGCGCGCGCTCGGCGCGGCCGACCGGCATGGCCTGCTGGCGGTGGATCGCG
CCGCCGATTTCGTGCTGTGGCAGGTCGCGTCGCCGGCCGAGCTTGCGTACTGGTTCGGCCGCAATCCATGCGCCGCCGTC
GTGCGGCGAGGGCGGGTATTCCGCAAGGGAGAAGGTTGGCAACGATGA

Upstream 100 bases:

>100_bases
ACGGCATCGTGATGGTGCCCGGAGCGCCGGCCGTCACGATGATTCACGATGAGATGTCCGCGCTGTGTCTGCGCGTGGCC
TTGCATAAGGAACCGGTCCG

Downstream 100 bases:

>100_bases
CCGCAGTGACAAGCTTGTTTGCGCCGCACGCGTTGTTGCCCGGCGGGTGGGCACGCAATGTACGGCTGCAATGGGACGCC
CACGGGGTGCTTACGTCGGT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKFNEAPSADGVWHHCHLLPAADPAQAIRDGAIVVEQGRIAWLGAFAALPDVYRHLPRHDANGAWITPGLVDCHTHLVYG
GQRADEFAMRLAGASYEEIARAGGGIVSTVRATREADEATLFAQASARLEPLLAEGVTAIEIKSGYGLSLEAERKQLRVA
RQLGETYGVAVHTTFLGAHALPPEYAGRADAYIELVCETMLPALAAEGLVDAVDAFCEGIGFSIAQTTRVFEAAARHGLP
VKLHAEQLSNLGGAALAARHKAISADHLEHLDEAGVVAMAEAGTVAVLLPGAYYFLRDTQLPPLALLRKHGVPMAISTDH
NPGTSPTTSLLLMMNMGCTIFRMTVPEVLAGVTTHAARALGAADRHGLLAVDRAADFVLWQVASPAELAYWFGRNPCAAV
VRRGRVFRKGEGWQR

Sequences:

>Translated_415_residues
MKFNEAPSADGVWHHCHLLPAADPAQAIRDGAIVVEQGRIAWLGAFAALPDVYRHLPRHDANGAWITPGLVDCHTHLVYG
GQRADEFAMRLAGASYEEIARAGGGIVSTVRATREADEATLFAQASARLEPLLAEGVTAIEIKSGYGLSLEAERKQLRVA
RQLGETYGVAVHTTFLGAHALPPEYAGRADAYIELVCETMLPALAAEGLVDAVDAFCEGIGFSIAQTTRVFEAAARHGLP
VKLHAEQLSNLGGAALAARHKAISADHLEHLDEAGVVAMAEAGTVAVLLPGAYYFLRDTQLPPLALLRKHGVPMAISTDH
NPGTSPTTSLLLMMNMGCTIFRMTVPEVLAGVTTHAARALGAADRHGLLAVDRAADFVLWQVASPAELAYWFGRNPCAAV
VRRGRVFRKGEGWQR
>Mature_415_residues
MKFNEAPSADGVWHHCHLLPAADPAQAIRDGAIVVEQGRIAWLGAFAALPDVYRHLPRHDANGAWITPGLVDCHTHLVYG
GQRADEFAMRLAGASYEEIARAGGGIVSTVRATREADEATLFAQASARLEPLLAEGVTAIEIKSGYGLSLEAERKQLRVA
RQLGETYGVAVHTTFLGAHALPPEYAGRADAYIELVCETMLPALAAEGLVDAVDAFCEGIGFSIAQTTRVFEAAARHGLP
VKLHAEQLSNLGGAALAARHKAISADHLEHLDEAGVVAMAEAGTVAVLLPGAYYFLRDTQLPPLALLRKHGVPMAISTDH
NPGTSPTTSLLLMMNMGCTIFRMTVPEVLAGVTTHAARALGAADRHGLLAVDRAADFVLWQVASPAELAYWFGRNPCAAV
VRRGRVFRKGEGWQR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=357, Percent_Identity=37.5350140056022, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17555004, Length=405, Percent_Identity=32.8395061728395, Blast_Score=215, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_RALME (Q1LJF1)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_584994.1
- ProteinModelPortal:   Q1LJF1
- SMR:   Q1LJF1
- STRING:   Q1LJF1
- GeneID:   4039680
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_2852
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   RMET266264:RMET_2852-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 44303; Mature: 44303

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: BINDING 83-83 BINDING 96-96 BINDING 146-146 BINDING 179-179 BINDING 247-247

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNEAPSADGVWHHCHLLPAADPAQAIRDGAIVVEQGRIAWLGAFAALPDVYRHLPRHD
CCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHCCCCC
ANGAWITPGLVDCHTHLVYGGQRADEFAMRLAGASYEEIARAGGGIVSTVRATREADEAT
CCCCEECCCHHHHHHHEEECCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
LFAQASARLEPLLAEGVTAIEIKSGYGLSLEAERKQLRVARQLGETYGVAVHTTFLGAHA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCEEEEEHHHCCCC
LPPEYAGRADAYIELVCETMLPALAAEGLVDAVDAFCEGIGFSIAQTTRVFEAAARHGLP
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
VKLHAEQLSNLGGAALAARHKAISADHLEHLDEAGVVAMAEAGTVAVLLPGAYYFLRDTQ
EEEEHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEECCC
LPPLALLRKHGVPMAISTDHNPGTSPTTSLLLMMNMGCTIFRMTVPEVLAGVTTHAARAL
CCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHH
GAADRHGLLAVDRAADFVLWQVASPAELAYWFGRNPCAAVVRRGRVFRKGEGWQR
CCCCCCCEEEEECCCCEEEEECCCCHHHHHHHCCCHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MKFNEAPSADGVWHHCHLLPAADPAQAIRDGAIVVEQGRIAWLGAFAALPDVYRHLPRHD
CCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHCCCCC
ANGAWITPGLVDCHTHLVYGGQRADEFAMRLAGASYEEIARAGGGIVSTVRATREADEAT
CCCCEECCCHHHHHHHEEECCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
LFAQASARLEPLLAEGVTAIEIKSGYGLSLEAERKQLRVARQLGETYGVAVHTTFLGAHA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCEEEEEHHHCCCC
LPPEYAGRADAYIELVCETMLPALAAEGLVDAVDAFCEGIGFSIAQTTRVFEAAARHGLP
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
VKLHAEQLSNLGGAALAARHKAISADHLEHLDEAGVVAMAEAGTVAVLLPGAYYFLRDTQ
EEEEHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEECCC
LPPLALLRKHGVPMAISTDHNPGTSPTTSLLLMMNMGCTIFRMTVPEVLAGVTTHAARAL
CCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHH
GAADRHGLLAVDRAADFVLWQVASPAELAYWFGRNPCAAVVRRGRVFRKGEGWQR
CCCCCCCEEEEECCCCEEEEECCCCHHHHHHHCCCHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA