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The map label for this gene is galU [H]

Identifier: 94311567

GI number: 94311567

Start: 2867634

End: 2868533

Strand: Direct

Name: galU [H]

Synonym: Rmet_2631

Alternate gene names: 94311567

Gene position: 2867634-2868533 (Clockwise)

Preceding gene: 94311566

Following gene: 94311569

Centisome position: 73.0

GC content: 62.89

Gene sequence:

>900_bases
ATGGAAAACCGCGTCACCAAGGCCGTCTTTCCCGTTGCAGGGCTAGGCACCCGGTTTCTGCCCGCCACCAAGGCGAGCCC
CAAGGAAATGCTGCCCGTGGTCGACAAGCCACTGATCCAGTACGCCGTGGAAGAAGCCATGGCCGCAGGCATTACCGAGA
TGATCTTCGTCACCGGGCGCTCCAAGCGCGCCATCGAGGATCACTTCGACAAGGCTTACGAACTGGAAGCGGAACTCGAG
GCCAAGAACAAACAGGCACTGCTCGATGTGGTGCGTTCGATCAAGCCAGCGAACGTCGAGTGCTATTACGTGCGCCAGCC
CGAGGCACTGGGTCTGGGCCACGCGGTGCTTTGCGCCGCCAAGCTCGTGGGCGACACGCCGTTTGCCGTGATGCTCGCCG
ACGACTTGCTCGACGGTGGCAAGGACCTGCCCGTGATGAAGCAGATGGTGGATATCTACAACCACTACAACTGCTCGGTA
CTCGGCGTGGAAGAGATCGCGCCCGAGCAAAGCCGCTCGTATGGCGTGATCGACGGCCGCGAGTGGGACGACCGCGTGAT
CAAGATGTCCGCCATCGTCGAGAAGCCGGCACCCGAGAAGGCACCGTCGAACCTGGGCGTGGTGGGTCGCTACATTCTCA
CCCCGCGCATCTTCGACCATATCCGCGAGCTTAAGCCGGGCGCCGGCGGCGAGATCCAGCTCACCGACGCCATCCAGTCG
ATGCTCGACCAGGAACAGGTGCTGGCCTATCGCTACAAAGGCGTGCGGTACGACTGCGGCAGCAAGCTCGGCTATCTGAA
GGCGACCGTCGAATTCGCCCTCAGGCACCCCGAGGTGCGCGACGAGTTCAGCGCCTATCTGTCGCAGCGCTGCACCAGCC
CGTCAAGCGTACCCGCCTGA

Upstream 100 bases:

>100_bases
TCCCCGGTTTCGTGCCGACTGCAGCGTCGGACGGAACCGGACAGACGGCACCCCTACCGTTACGGCACGGTATCACTCCG
GATAAACAAGGAAGGCTGAA

Downstream 100 bases:

>100_bases
CATCCGCCTGAAAAAACGAAGCCGCCCCGGAAGAGGCGGCTTCGGCAGGAAGGCAGAAAAAAACCCCGCTTTGTTACCGA
AGCGGGGTTTTTCTTTATTC

Product: glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MENRVTKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAMAAGITEMIFVTGRSKRAIEDHFDKAYELEAELE
AKNKQALLDVVRSIKPANVECYYVRQPEALGLGHAVLCAAKLVGDTPFAVMLADDLLDGGKDLPVMKQMVDIYNHYNCSV
LGVEEIAPEQSRSYGVIDGREWDDRVIKMSAIVEKPAPEKAPSNLGVVGRYILTPRIFDHIRELKPGAGGEIQLTDAIQS
MLDQEQVLAYRYKGVRYDCGSKLGYLKATVEFALRHPEVRDEFSAYLSQRCTSPSSVPA

Sequences:

>Translated_299_residues
MENRVTKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAMAAGITEMIFVTGRSKRAIEDHFDKAYELEAELE
AKNKQALLDVVRSIKPANVECYYVRQPEALGLGHAVLCAAKLVGDTPFAVMLADDLLDGGKDLPVMKQMVDIYNHYNCSV
LGVEEIAPEQSRSYGVIDGREWDDRVIKMSAIVEKPAPEKAPSNLGVVGRYILTPRIFDHIRELKPGAGGEIQLTDAIQS
MLDQEQVLAYRYKGVRYDCGSKLGYLKATVEFALRHPEVRDEFSAYLSQRCTSPSSVPA
>Mature_299_residues
MENRVTKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAMAAGITEMIFVTGRSKRAIEDHFDKAYELEAELE
AKNKQALLDVVRSIKPANVECYYVRQPEALGLGHAVLCAAKLVGDTPFAVMLADDLLDGGKDLPVMKQMVDIYNHYNCSV
LGVEEIAPEQSRSYGVIDGREWDDRVIKMSAIVEKPAPEKAPSNLGVVGRYILTPRIFDHIRELKPGAGGEIQLTDAIQS
MLDQEQVLAYRYKGVRYDCGSKLGYLKATVEFALRHPEVRDEFSAYLSQRCTSPSSVPA

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a mem

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=296, Percent_Identity=50, Blast_Score=270, Evalue=9e-74,
Organism=Escherichia coli, GI1788355, Length=277, Percent_Identity=46.5703971119134, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1790224, Length=242, Percent_Identity=25.2066115702479, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788351, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 33050; Mature: 33050

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRVTKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAMAAGITEMIFVTGR
CCCCHHHHHHCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECC
SKRAIEDHFDKAYELEAELEAKNKQALLDVVRSIKPANVECYYVRQPEALGLGHAVLCAA
CCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHHHHHH
KLVGDTPFAVMLADDLLDGGKDLPVMKQMVDIYNHYNCSVLGVEEIAPEQSRSYGVIDGR
HHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCCCC
EWDDRVIKMSAIVEKPAPEKAPSNLGVVGRYILTPRIFDHIRELKPGAGGEIQLTDAIQS
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
MLDQEQVLAYRYKGVRYDCGSKLGYLKATVEFALRHPEVRDEFSAYLSQRCTSPSSVPA
HHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MENRVTKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAMAAGITEMIFVTGR
CCCCHHHHHHCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECC
SKRAIEDHFDKAYELEAELEAKNKQALLDVVRSIKPANVECYYVRQPEALGLGHAVLCAA
CCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHHHHHH
KLVGDTPFAVMLADDLLDGGKDLPVMKQMVDIYNHYNCSVLGVEEIAPEQSRSYGVIDGR
HHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCCCC
EWDDRVIKMSAIVEKPAPEKAPSNLGVVGRYILTPRIFDHIRELKPGAGGEIQLTDAIQS
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
MLDQEQVLAYRYKGVRYDCGSKLGYLKATVEFALRHPEVRDEFSAYLSQRCTSPSSVPA
HHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA