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The map label for this gene is lysN [H]

Identifier: 94311449

GI number: 94311449

Start: 2727578

End: 2728792

Strand: Direct

Name: lysN [H]

Synonym: Rmet_2513

Alternate gene names: 94311449

Gene position: 2727578-2728792 (Clockwise)

Preceding gene: 94311448

Following gene: 94311450

Centisome position: 69.44

GC content: 65.43

Gene sequence:

>1215_bases
TTGAATTCCCCCACCACGAGACCAATCATGAAATGGGCCATCTCCCGCCGGGCGCAGCAACTGACCAGCTCGGCCATCCG
TGAAATCCTGAAAGTCACCGAGCGTCCGGAAGTGATTTCGTTCGCCGGCGGCCTGCCCTCGCCGGCTTCGTTCCCGGTAG
CGGCCATGGAAGCGGCGGTGGCCCGTGTATTCGCCGACAACCCGCAAAGCGCGCTGCAGTACGCGGCCACAGAAGGCTTC
ATGCCGCTGCGCGAGTTCGTGGCCAAGCGCTACAACGTCGATGTGGAACGCGTGATGATCACCACGGGTTCGCAACAGGC
GCTGGACCTGATCGCCAAGGTGATGATCGACCCGGGCAGCCCGGTGTTGGTGGAAACGCCGAGCTACCTGGGCGCGCTGC
AGGCGTTCTCGCTGTTCGAGCCGGAATTCGTGTCGATCCCGTCCGACGAAAAGGGCCTGATCCCCGAGGCGCTGACGCCC
GAGCTGACCGCCGGCGCACGCTTCCTGTACGCCCTGCCGAACTTCCAGAACCCCACCGGCCGCCGCCTGCCGCTGGAGCG
CCGCCAGGAACTGGTCAAGCGCGCCAAGGAACTCGGCGTGCTGCTGGTCGAGGACGATCCGTACGGCGAACTGAGCTACT
CGGGCAACCAGTTGCCGTCGCTGCTGTCGATGAACCCGGACGGCGTGATCTACATGGGCTCGTTCTCGAAGATCCTGGCG
CCCGGTATGCGCCTGGGTTTCGTCATCGCCCCGCCCGACCTGCATTTCAAGCTATGCCAGGCCAAGCAGGCCTCGGACCT
GCACACGCCGACGTTCACACAGCGCATCGCCTATGAAACGATCAAGGACGGCCTGCTCGAACAGCACATCCCGACCATTC
GCGAGCTCTACGGCAAGCAATGCGCGTTCATGCTGGACGCGCTGAAGCGCCACATGCCGGCCGGCGTGACATGGAACGCG
CCCGAGGGCGGCATGTTCATCTGGGTGGAGCTGCCTGAGGGTCTGGACAGCATGAAGATCCTGGAAGAAGCCGTGCGCCG
CAACGTGGCCTACGTGCCAGGCGCGCCGTTCTACGCGGGCAGCCCGCGCAAGAACACGCTGCGCCTGGCATTCGTGACCG
TTTCGGCCGAGCGCATCGAGCAGGGCGTGTCGATCCTGGGCGAGGTGTTCCGCGAAGCGATCGCGCAAGCCGCGCCGCAG
GCACGGGCGGCCTGA

Upstream 100 bases:

>100_bases
GGGCGCCTGCGTCGAGATCGAAATGATCGTCGAGATCTGACGTCGTCGGAAACCACGCAACACAGATAATGCCGCGCCGC
CTCTTGCGGAGGCCGGCGCA

Downstream 100 bases:

>100_bases
GCCGGCACGCTACAACCAACCCGAGGAGCCATCGAACATGCTTCGCATCTGGGGCAGGCTGTCGTCAATCAATGTCCAGA
AGGTGGTCTGGTGCGCGCGC

Product: Aminotransferase family protein

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNSPTTRPIMKWAISRRAQQLTSSAIREILKVTERPEVISFAGGLPSPASFPVAAMEAAVARVFADNPQSALQYAATEGF
MPLREFVAKRYNVDVERVMITTGSQQALDLIAKVMIDPGSPVLVETPSYLGALQAFSLFEPEFVSIPSDEKGLIPEALTP
ELTAGARFLYALPNFQNPTGRRLPLERRQELVKRAKELGVLLVEDDPYGELSYSGNQLPSLLSMNPDGVIYMGSFSKILA
PGMRLGFVIAPPDLHFKLCQAKQASDLHTPTFTQRIAYETIKDGLLEQHIPTIRELYGKQCAFMLDALKRHMPAGVTWNA
PEGGMFIWVELPEGLDSMKILEEAVRRNVAYVPGAPFYAGSPRKNTLRLAFVTVSAERIEQGVSILGEVFREAIAQAAPQ
ARAA

Sequences:

>Translated_404_residues
MNSPTTRPIMKWAISRRAQQLTSSAIREILKVTERPEVISFAGGLPSPASFPVAAMEAAVARVFADNPQSALQYAATEGF
MPLREFVAKRYNVDVERVMITTGSQQALDLIAKVMIDPGSPVLVETPSYLGALQAFSLFEPEFVSIPSDEKGLIPEALTP
ELTAGARFLYALPNFQNPTGRRLPLERRQELVKRAKELGVLLVEDDPYGELSYSGNQLPSLLSMNPDGVIYMGSFSKILA
PGMRLGFVIAPPDLHFKLCQAKQASDLHTPTFTQRIAYETIKDGLLEQHIPTIRELYGKQCAFMLDALKRHMPAGVTWNA
PEGGMFIWVELPEGLDSMKILEEAVRRNVAYVPGAPFYAGSPRKNTLRLAFVTVSAERIEQGVSILGEVFREAIAQAAPQ
ARAA
>Mature_404_residues
MNSPTTRPIMKWAISRRAQQLTSSAIREILKVTERPEVISFAGGLPSPASFPVAAMEAAVARVFADNPQSALQYAATEGF
MPLREFVAKRYNVDVERVMITTGSQQALDLIAKVMIDPGSPVLVETPSYLGALQAFSLFEPEFVSIPSDEKGLIPEALTP
ELTAGARFLYALPNFQNPTGRRLPLERRQELVKRAKELGVLLVEDDPYGELSYSGNQLPSLLSMNPDGVIYMGSFSKILA
PGMRLGFVIAPPDLHFKLCQAKQASDLHTPTFTQRIAYETIKDGLLEQHIPTIRELYGKQCAFMLDALKRHMPAGVTWNA
PEGGMFIWVELPEGLDSMKILEEAVRRNVAYVPGAPFYAGSPRKNTLRLAFVTVSAERIEQGVSILGEVFREAIAQAAPQ
ARAA

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=412, Percent_Identity=30.5825242718447, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI33469970, Length=412, Percent_Identity=30.5825242718447, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI95147551, Length=294, Percent_Identity=24.1496598639456, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI169881279, Length=294, Percent_Identity=24.1496598639456, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787710, Length=384, Percent_Identity=29.1666666666667, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790797, Length=401, Percent_Identity=27.431421446384, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=25.6, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321929, Length=441, Percent_Identity=24.9433106575964, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321000, Length=246, Percent_Identity=27.2357723577236, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321236, Length=473, Percent_Identity=23.6786469344609, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356535, Length=395, Percent_Identity=25.8227848101266, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 44404; Mature: 44404

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPTTRPIMKWAISRRAQQLTSSAIREILKVTERPEVISFAGGLPSPASFPVAAMEAAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHH
ARVFADNPQSALQYAATEGFMPLREFVAKRYNVDVERVMITTGSQQALDLIAKVMIDPGS
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCC
PVLVETPSYLGALQAFSLFEPEFVSIPSDEKGLIPEALTPELTAGARFLYALPNFQNPTG
CEEEECCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCC
RRLPLERRQELVKRAKELGVLLVEDDPYGELSYSGNQLPSLLSMNPDGVIYMGSFSKILA
CCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCEEEECCCHHHHC
PGMRLGFVIAPPDLHFKLCQAKQASDLHTPTFTQRIAYETIKDGLLEQHIPTIRELYGKQ
CCCCEEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
CAFMLDALKRHMPAGVTWNAPEGGMFIWVELPEGLDSMKILEEAVRRNVAYVPGAPFYAG
HHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEECCCCCCCCC
SPRKNTLRLAFVTVSAERIEQGVSILGEVFREAIAQAAPQARAA
CCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNSPTTRPIMKWAISRRAQQLTSSAIREILKVTERPEVISFAGGLPSPASFPVAAMEAAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHH
ARVFADNPQSALQYAATEGFMPLREFVAKRYNVDVERVMITTGSQQALDLIAKVMIDPGS
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCC
PVLVETPSYLGALQAFSLFEPEFVSIPSDEKGLIPEALTPELTAGARFLYALPNFQNPTG
CEEEECCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCCCC
RRLPLERRQELVKRAKELGVLLVEDDPYGELSYSGNQLPSLLSMNPDGVIYMGSFSKILA
CCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCEEEECCCHHHHC
PGMRLGFVIAPPDLHFKLCQAKQASDLHTPTFTQRIAYETIKDGLLEQHIPTIRELYGKQ
CCCCEEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
CAFMLDALKRHMPAGVTWNAPEGGMFIWVELPEGLDSMKILEEAVRRNVAYVPGAPFYAG
HHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEECCCCCCCCC
SPRKNTLRLAFVTVSAERIEQGVSILGEVFREAIAQAAPQARAA
CCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA