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The map label for this gene is mcl1 [H]

Identifier: 94311426

GI number: 94311426

Start: 2702859

End: 2703839

Strand: Direct

Name: mcl1 [H]

Synonym: Rmet_2490

Alternate gene names: 94311426

Gene position: 2702859-2703839 (Clockwise)

Preceding gene: 94311425

Following gene: 94311427

Centisome position: 68.81

GC content: 63.91

Gene sequence:

>981_bases
GTGCATCCATCCGAGGTCTTGTTCCAGGGCGAAGCCATTCCGGTGCAACTGCCGGTATGTGACCACTATGCCGGTAGCGA
AAAGCTCATGCGCAAATCGCTTGCCCTGCAGCAAGCGCTCGGGCCAGTGTTCGATATCACGTTCGACTGCGAGGACGGCG
CGGCGGTCGGGCTCGAACGCGAGCACGCCACGCTGTGCGCGCAACTGATCAACAGCGCCGAAAATGCGCACAACCGTGTG
GGCGTGCGCATCCACGATCCGGCGCACCCGTGCTGGCGCGAAGACGTCGACATCCTGGTGAGGACCGCCGGCGCCCGACT
GGCCTATGTCGTGGTCCCGAAAGTAACCGACGTGGTGGAAGTGGCCCGTGTGACCGATCACGTGAACCAGGTAGCGCGCG
CGTCCGGCATCGCCCGCCACATCCCAATACACGTGCTGATTGAGACACATTCGGCGCTCGAGCAAGTCTTCGACATCGCC
TCGCTCGTGCAGGTGGAGTGCCTGAGCTTCGGGCTGATGGATTTTGTCTCGGCGCACCACGGCGCGATTCCGGGCGAGGC
CATGCGCTCGCCCGAACAGTTCGAGCATCCGCTGATCCGCCGGGCCATGCTCGAGATTTCGGCAGCCTGCCACCGCCATG
GCAAAGTACCGTCACACAATGTCAGCACCGATGTGCAGAACCCCCAACGCTCGGGCGACGACGCATACCGGGCGCGCGCC
GAGTTCGGCTATCTGCGTAAATGGAGCATCCATCCGGGCCAGATCGAGCCGATTGTGTCGGCCTTCCGCCCCGGGGACAG
CGAAATCGGCGCAGCAAGCCAGATCCTGCTTGCGGCGCACGAGAACAACTGGGCGCCGATCCGCCACGACGGCCAGCTCC
ATGACCGCGCAAGCTATCGCTATTACTGGTCGCTGCTGCAGCGTGCCCATGCCACCGGCACGAAACTGCCCTCGCCGGTG
ACGGAGTTGTTCTTCGACTGA

Upstream 100 bases:

>100_bases
GGTTCCGCATCGATTCTCGAAAATCGGCGCGGACCCCGGTTTTTCTTTTGGGCGCGTAAATCCCACTTTTGAATAACCCT
ACATTTTCTCCGTATTTAAC

Downstream 100 bases:

>100_bases
CACCAGTCCGAAGCACGCGGACTGCTCATTTTTACCTTGAAGTGGCCGATGACAAACCGTCCGCGAACAATTGTGTAACC
AATGACTGACGGGCTTCGCC

Product: putative citrate lyase subunit beta (citE)

Products: NA

Alternate protein names: (3S)-malyl-CoA/beta-methylmalyl-CoA lyase; L-malyl-CoA/beta-methylmalyl-CoA lyase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MHPSEVLFQGEAIPVQLPVCDHYAGSEKLMRKSLALQQALGPVFDITFDCEDGAAVGLEREHATLCAQLINSAENAHNRV
GVRIHDPAHPCWREDVDILVRTAGARLAYVVVPKVTDVVEVARVTDHVNQVARASGIARHIPIHVLIETHSALEQVFDIA
SLVQVECLSFGLMDFVSAHHGAIPGEAMRSPEQFEHPLIRRAMLEISAACHRHGKVPSHNVSTDVQNPQRSGDDAYRARA
EFGYLRKWSIHPGQIEPIVSAFRPGDSEIGAASQILLAAHENNWAPIRHDGQLHDRASYRYYWSLLQRAHATGTKLPSPV
TELFFD

Sequences:

>Translated_326_residues
MHPSEVLFQGEAIPVQLPVCDHYAGSEKLMRKSLALQQALGPVFDITFDCEDGAAVGLEREHATLCAQLINSAENAHNRV
GVRIHDPAHPCWREDVDILVRTAGARLAYVVVPKVTDVVEVARVTDHVNQVARASGIARHIPIHVLIETHSALEQVFDIA
SLVQVECLSFGLMDFVSAHHGAIPGEAMRSPEQFEHPLIRRAMLEISAACHRHGKVPSHNVSTDVQNPQRSGDDAYRARA
EFGYLRKWSIHPGQIEPIVSAFRPGDSEIGAASQILLAAHENNWAPIRHDGQLHDRASYRYYWSLLQRAHATGTKLPSPV
TELFFD
>Mature_326_residues
MHPSEVLFQGEAIPVQLPVCDHYAGSEKLMRKSLALQQALGPVFDITFDCEDGAAVGLEREHATLCAQLINSAENAHNRV
GVRIHDPAHPCWREDVDILVRTAGARLAYVVVPKVTDVVEVARVTDHVNQVARASGIARHIPIHVLIETHSALEQVFDIA
SLVQVECLSFGLMDFVSAHHGAIPGEAMRSPEQFEHPLIRRAMLEISAACHRHGKVPSHNVSTDVQNPQRSGDDAYRARA
EFGYLRKWSIHPGQIEPIVSAFRPGDSEIGAASQILLAAHENNWAPIRHDGQLHDRASYRYYWSLLQRAHATGTKLPSPV
TELFFD

Specific function: Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to beta-methylmalyl-CoA [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.24 [H]

Molecular weight: Translated: 36095; Mature: 36095

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPSEVLFQGEAIPVQLPVCDHYAGSEKLMRKSLALQQALGPVFDITFDCEDGAAVGLER
CCCHHEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCH
EHATLCAQLINSAENAHNRVGVRIHDPAHPCWREDVDILVRTAGARLAYVVVPKVTDVVE
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHH
VARVTDHVNQVARASGIARHIPIHVLIETHSALEQVFDIASLVQVECLSFGLMDFVSAHH
HHHHHHHHHHHHHHHCCHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAIPGEAMRSPEQFEHPLIRRAMLEISAACHRHGKVPSHNVSTDVQNPQRSGDDAYRARA
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
EFGYLRKWSIHPGQIEPIVSAFRPGDSEIGAASQILLAAHENNWAPIRHDGQLHDRASYR
HHCCCEEECCCCCCHHHHHHHHCCCCCCCCCHHEEEEEEECCCCCCCCCCCCCCHHHHHH
YYWSLLQRAHATGTKLPSPVTELFFD
HHHHHHHHHHHCCCCCCCHHHHHHCC
>Mature Secondary Structure
MHPSEVLFQGEAIPVQLPVCDHYAGSEKLMRKSLALQQALGPVFDITFDCEDGAAVGLER
CCCHHEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCH
EHATLCAQLINSAENAHNRVGVRIHDPAHPCWREDVDILVRTAGARLAYVVVPKVTDVVE
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHH
VARVTDHVNQVARASGIARHIPIHVLIETHSALEQVFDIASLVQVECLSFGLMDFVSAHH
HHHHHHHHHHHHHHHCCHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAIPGEAMRSPEQFEHPLIRRAMLEISAACHRHGKVPSHNVSTDVQNPQRSGDDAYRARA
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
EFGYLRKWSIHPGQIEPIVSAFRPGDSEIGAASQILLAAHENNWAPIRHDGQLHDRASYR
HHCCCEEECCCCCCHHHHHHHHCCCCCCCCCHHEEEEEEECCCCCCCCCCCCCCHHHHHH
YYWSLLQRAHATGTKLPSPVTELFFD
HHHHHHHHHHHCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA