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The map label for this gene is livM1 [H]

Identifier: 94311414

GI number: 94311414

Start: 2690909

End: 2692183

Strand: Reverse

Name: livM1 [H]

Synonym: Rmet_2478

Alternate gene names: 94311414

Gene position: 2692183-2690909 (Counterclockwise)

Preceding gene: 94311415

Following gene: 94311413

Centisome position: 68.54

GC content: 65.96

Gene sequence:

>1275_bases
ATGACTCAAGCGACTTCGATTTCGCGGGCGTCCGTCCCGCAAACGTCGGTCTCCGACACGCTGAAGAACGCGGTGACGGC
CGCCGTGCTGACGGCCATCCTGACCGTGCCGCTGCTCGGGCTGCAACTGAAGCTCGATGGCTACAAGGTGGTGCTCGAGC
CGCACTGGCGTCCGGTATGGATCGCCGTGGCCGTGGTGTTCATCTTCCAGTTGTTCAAGCCGATGCTGACGCGCGCGCGC
GGCGCCGTGAAGCTGCCGGCGCTGCCCGCGATGGGCGCGCAGCGGCAGCGCAGGGCGGTGTGGCTGCTGCTGGCCGTGGG
GCTGGTGTTTCCGTTCCTCGGCTCGCGCGGCGCGGTGGACGTGGCCACGCTGGCGCTGATCTACGTGATCCTGGGCCTGG
GCCTGAACATCGTGGTGGGCTTTGCCGGTCTGCTCGACCTGGGCTATGTGGGCTTCTACGCCGTGGGTGGCTACACCTAC
GCGCTGCTGAACCAGTACTTCGGCCTGACGTTCTGGGAGTGCCTGCCGCTGGCCGCTGGTCTGGCCGCGACGTTCGGCTT
CGTGCTCGGTTTCCCGGTGCTCCGGCTGCGTGGTGACTACCTGGCCATCGTGACGCTGGGCTTCGGCGAAATCATTCGCC
TGCTGCTGAACAACCTGACCAGCCTTACCGGCGGTCCGGATGGCGTCTCGGGTATTCCGAAGCCGACCGTGTTCGGTATC
GAACTGGCACGCAGCGCCAGCGTGGAAGGGGCGAAGACGTTCAATGACCTGATCGGTATTCCCTATACCGGCCAGCACAT
GGTGATCTTCCTGTACCTGCTCGGGCTGCTGCTGGTGGGCTTCACGCTGTTCGTAACCAGTCGTCTGATCCGGATGCCGA
TGGGCCGTGCCTGGGAGGCACTGCGCGAGGACGAGATCGCGTGCCGCTCGCTGGGCCTGAATCCCACGCGCATCAAGCTG
TCCGCGTTCACGCTGGGCGCATCGTTCGCCGGTCTGGCCGGCGCGTTCTTCGCGGCGCGCCAGGGGCTGGTCACTCCGGA
ATCCTTCACGTTCATCGAGTCCGCGCTGATCCTGGCCGTGGTCGTGCTCGGTGGCATGGGTTCGCAGCTTGGCGTGATCC
TGGCGGCCATCCTGCTGACCGTGCTGCCCGAGGTGGCGCGTGACTTTGCCGAGTACCGGATGCTGATTTTCGGCCTGGTG
ATGGTGCTGATGATGATGTGGCGTCCGCAGGGCCTGCTGCCCGCAAGCCGTCCCCACGTGGAGTTGCCGCGATGA

Upstream 100 bases:

>100_bases
GGACGTGGTGGCGTTCGGCCTGCTGGTCCTGGTGCTGCTCTTCCGTCCCACGGGCCTGCTCGGCAAGCCCGACGTGGAAA
AGGTCTAAGGGGAGGACGAC

Downstream 100 bases:

>100_bases
GCGCAGAAATGCTGAAAGTATCCGGCCTGCAGATGCGCTTCGGCGGTCTGCTGGCCGTCGACGGCATCGAGTTCGATGTG
CGTCGTGACGAGGTCTTCGC

Product: leucine/isoleucine/valine transporter permease subunit

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTQATSISRASVPQTSVSDTLKNAVTAAVLTAILTVPLLGLQLKLDGYKVVLEPHWRPVWIAVAVVFIFQLFKPMLTRAR
GAVKLPALPAMGAQRQRRAVWLLLAVGLVFPFLGSRGAVDVATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTY
ALLNQYFGLTFWECLPLAAGLAATFGFVLGFPVLRLRGDYLAIVTLGFGEIIRLLLNNLTSLTGGPDGVSGIPKPTVFGI
ELARSASVEGAKTFNDLIGIPYTGQHMVIFLYLLGLLLVGFTLFVTSRLIRMPMGRAWEALREDEIACRSLGLNPTRIKL
SAFTLGASFAGLAGAFFAARQGLVTPESFTFIESALILAVVVLGGMGSQLGVILAAILLTVLPEVARDFAEYRMLIFGLV
MVLMMMWRPQGLLPASRPHVELPR

Sequences:

>Translated_424_residues
MTQATSISRASVPQTSVSDTLKNAVTAAVLTAILTVPLLGLQLKLDGYKVVLEPHWRPVWIAVAVVFIFQLFKPMLTRAR
GAVKLPALPAMGAQRQRRAVWLLLAVGLVFPFLGSRGAVDVATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTY
ALLNQYFGLTFWECLPLAAGLAATFGFVLGFPVLRLRGDYLAIVTLGFGEIIRLLLNNLTSLTGGPDGVSGIPKPTVFGI
ELARSASVEGAKTFNDLIGIPYTGQHMVIFLYLLGLLLVGFTLFVTSRLIRMPMGRAWEALREDEIACRSLGLNPTRIKL
SAFTLGASFAGLAGAFFAARQGLVTPESFTFIESALILAVVVLGGMGSQLGVILAAILLTVLPEVARDFAEYRMLIFGLV
MVLMMMWRPQGLLPASRPHVELPR
>Mature_423_residues
TQATSISRASVPQTSVSDTLKNAVTAAVLTAILTVPLLGLQLKLDGYKVVLEPHWRPVWIAVAVVFIFQLFKPMLTRARG
AVKLPALPAMGAQRQRRAVWLLLAVGLVFPFLGSRGAVDVATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTYA
LLNQYFGLTFWECLPLAAGLAATFGFVLGFPVLRLRGDYLAIVTLGFGEIIRLLLNNLTSLTGGPDGVSGIPKPTVFGIE
LARSASVEGAKTFNDLIGIPYTGQHMVIFLYLLGLLLVGFTLFVTSRLIRMPMGRAWEALREDEIACRSLGLNPTRIKLS
AFTLGASFAGLAGAFFAARQGLVTPESFTFIESALILAVVVLGGMGSQLGVILAAILLTVLPEVARDFAEYRMLIFGLVM
VLMMMWRPQGLLPASRPHVELPR

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=409, Percent_Identity=59.4132029339853, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 45585; Mature: 45454

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQATSISRASVPQTSVSDTLKNAVTAAVLTAILTVPLLGLQLKLDGYKVVLEPHWRPVW
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEEEECCCCCHHH
IAVAVVFIFQLFKPMLTRARGAVKLPALPAMGAQRQRRAVWLLLAVGLVFPFLGSRGAVD
HHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
VATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTYALLNQYFGLTFWECLPLAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAATFGFVLGFPVLRLRGDYLAIVTLGFGEIIRLLLNNLTSLTGGPDGVSGIPKPTVFGI
HHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
ELARSASVEGAKTFNDLIGIPYTGQHMVIFLYLLGLLLVGFTLFVTSRLIRMPMGRAWEA
HHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LREDEIACRSLGLNPTRIKLSAFTLGASFAGLAGAFFAARQGLVTPESFTFIESALILAV
HHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VVLGGMGSQLGVILAAILLTVLPEVARDFAEYRMLIFGLVMVLMMMWRPQGLLPASRPHV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ELPR
CCCC
>Mature Secondary Structure 
TQATSISRASVPQTSVSDTLKNAVTAAVLTAILTVPLLGLQLKLDGYKVVLEPHWRPVW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEEEECCCCCHHH
IAVAVVFIFQLFKPMLTRARGAVKLPALPAMGAQRQRRAVWLLLAVGLVFPFLGSRGAVD
HHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHH
VATLALIYVILGLGLNIVVGFAGLLDLGYVGFYAVGGYTYALLNQYFGLTFWECLPLAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAATFGFVLGFPVLRLRGDYLAIVTLGFGEIIRLLLNNLTSLTGGPDGVSGIPKPTVFGI
HHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
ELARSASVEGAKTFNDLIGIPYTGQHMVIFLYLLGLLLVGFTLFVTSRLIRMPMGRAWEA
HHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LREDEIACRSLGLNPTRIKLSAFTLGASFAGLAGAFFAARQGLVTPESFTFIESALILAV
HHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VVLGGMGSQLGVILAAILLTVLPEVARDFAEYRMLIFGLVMVLMMMWRPQGLLPASRPHV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ELPR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]