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The map label for this gene is rhtB [C]

Identifier: 94311390

GI number: 94311390

Start: 2665731

End: 2666339

Strand: Direct

Name: rhtB [C]

Synonym: Rmet_2454

Alternate gene names: 94311390

Gene position: 2665731-2666339 (Clockwise)

Preceding gene: 94311389

Following gene: 94311391

Centisome position: 67.86

GC content: 63.22

Gene sequence:

>609_bases
ATGCTCGACACGCTCCCTTTCCTTCCTTTCCTGCTTTTCGCGATCGTTGCGTCGATCACGCCCGGCCCGACCAACGTCAT
CGTACTGAGCCACAGCGCCCGCCGCGGAATCGTGGCAACGCTGCCAATCATCATAGGCGGCTGTGGCGGCGCAGCCTTGC
TGGTACTGGCCGTCGGCATCGGCATTGGCGATGCCTTGACTGACCATCCGCAGGTCCAACGCGTGATGGCCTGGAGCGGC
GTGCTCTGGCTCTCCTGGCTGGCGTGGCAGATCTGGAGCAGCCCGGCGGCAAGTGTCGAGGTCGACAGCAAAGACAAACG
GTCACTCGGCCTCGCAGGCGCGGCCGCCTTGCAGCTCGTGAATCCGAAGACCTGGATGATGGCGCTGGCCGTGGTAAGTG
TTTTCGCGGGCCACGGATCAGACCAGTCGCATCAGGTGATCCTGCTGTCACTCACCTTCTTTGTCGTCTCGCTGCCCTGC
ATGGGCGTATGGGCGGCCCTCGGCGCGGGTGCCACCCGCTTCATCCGATCGCCCGCCATGATGAAGCGCTTTGACCGCCT
CATGGCGCTTGTACTACTGATCTCGGCATGGTGCAGCCTGTTGCAGTAA

Upstream 100 bases:

>100_bases
ACGCTGGTTCCGGCGCGCCTATGGCCTGACACCCGCGCACTACCGCAAGCGCTGCTCAAATCTTCCAGACGCGTGAGACA
TCGGCCGCAACAATGGCCAC

Downstream 100 bases:

>100_bases
CGCCAATCCCTCGTTTGGCGGTCGTCGCGCACATTTCCTGGTGTATGATCTCGGATTGCCCAAGTTTACTTGACTCACCC
CCCGGTATACCTGTAAAAGC

Product: LysE family transporter

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: Amino Acid Transporter LysE; Lysine Exporter Protein; Transporter LysE Family; Threonine Efflux Protein; Transporter Protein; RhtB Family Transporter; LysE Family Protein; LysE Family Transporter; Translocator Protein LysE Family; Amino Acid Efflux Pump RhtB Family Protein; ABC Transporter; LysE Type Translocator Family; LOW QUALITY PROTEIN Lysine Exporter Protein LysE; Amino Acid Efflux Protein LysE Family; Neutral Amino-Acid Efflux System; Transporter-LysE Family; Transmembrane Transporter Protein LysE Type Translocator; Amino Acid Efflux Protein; Lysing Exporter Protein

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLDTLPFLPFLLFAIVASITPGPTNVIVLSHSARRGIVATLPIIIGGCGGAALLVLAVGIGIGDALTDHPQVQRVMAWSG
VLWLSWLAWQIWSSPAASVEVDSKDKRSLGLAGAAALQLVNPKTWMMALAVVSVFAGHGSDQSHQVILLSLTFFVVSLPC
MGVWAALGAGATRFIRSPAMMKRFDRLMALVLLISAWCSLLQ

Sequences:

>Translated_202_residues
MLDTLPFLPFLLFAIVASITPGPTNVIVLSHSARRGIVATLPIIIGGCGGAALLVLAVGIGIGDALTDHPQVQRVMAWSG
VLWLSWLAWQIWSSPAASVEVDSKDKRSLGLAGAAALQLVNPKTWMMALAVVSVFAGHGSDQSHQVILLSLTFFVVSLPC
MGVWAALGAGATRFIRSPAMMKRFDRLMALVLLISAWCSLLQ
>Mature_202_residues
MLDTLPFLPFLLFAIVASITPGPTNVIVLSHSARRGIVATLPIIIGGCGGAALLVLAVGIGIGDALTDHPQVQRVMAWSG
VLWLSWLAWQIWSSPAASVEVDSKDKRSLGLAGAAALQLVNPKTWMMALAVVSVFAGHGSDQSHQVILLSLTFFVVSLPC
MGVWAALGAGATRFIRSPAMMKRFDRLMALVLLISAWCSLLQ

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994979, Length=192, Percent_Identity=27.0833333333333, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21429; Mature: 21429

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTLPFLPFLLFAIVASITPGPTNVIVLSHSARRGIVATLPIIIGGCGGAALLVLAVGI
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHEEHHHHHCCCCHHHHHHHHHHC
GIGDALTDHPQVQRVMAWSGVLWLSWLAWQIWSSPAASVEVDSKDKRSLGLAGAAALQLV
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCHHHHHHHHHC
NPKTWMMALAVVSVFAGHGSDQSHQVILLSLTFFVVSLPCMGVWAALGAGATRFIRSPAM
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
MKRFDRLMALVLLISAWCSLLQ
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDTLPFLPFLLFAIVASITPGPTNVIVLSHSARRGIVATLPIIIGGCGGAALLVLAVGI
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHEEHHHHHCCCCHHHHHHHHHHC
GIGDALTDHPQVQRVMAWSGVLWLSWLAWQIWSSPAASVEVDSKDKRSLGLAGAAALQLV
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCHHHHHHHHHC
NPKTWMMALAVVSVFAGHGSDQSHQVILLSLTFFVVSLPCMGVWAALGAGATRFIRSPAM
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
MKRFDRLMALVLLISAWCSLLQ
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA