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The map label for this gene is pncB [H]

Identifier: 94311385

GI number: 94311385

Start: 2660689

End: 2661888

Strand: Reverse

Name: pncB [H]

Synonym: Rmet_2449

Alternate gene names: 94311385

Gene position: 2661888-2660689 (Counterclockwise)

Preceding gene: 94311386

Following gene: 94311384

Centisome position: 67.77

GC content: 61.25

Gene sequence:

>1200_bases
ATGCCCCCGTCTGGCCTCGTTATGATCATCCGTTCCCTGCTCGACACTGACCTGTACAAATTCACGATGATGCAGGTGGT
GCTGCATCACTTCCCGCAGGCCCAGGTGGAGTACCGCTTCAAGTGCCGCAACGCCGGGGTCGACCTGACGCCGTACGTCG
ACGAGATCCGGTCCCAGATCACGCAGCTTTGTCAGTTGCGATTCACCGACGATGAACTCAATTACCTGCGTGGCCTGCGC
TTCATCAAAAGCGACTTTGTCGAGTTTCTGGCGCTGTTCCATCTGAACGAGAAGTACGTGCAGGTGCTGCCGTCGGCCAA
GGGTAATGGCGAAATCGAGATCATCATCAAGGGTCCGTGGCTTCATACGATCCTGTTCGAGATTCCGCTGCTGGCCATCG
TCAACGAGGTGTACTTCCGACGTACCCAGCCGAAGCCCGATCTGGCGGAGGGCCGTCGCCGGCTGCAGGCCAAGCTGGAG
CTGCTCGCGGCGCCGCCCTATGTGGATTGCGTGATCGCGGACTACGGCACCCGCCGCCGGTTCTCGTGCGACTGGCAGGA
GGAGGTCCTGCTGTCGATGCGCGACGCCATTGGCCCGCAATTGGCCGGCACCAGCAACGTCCACTTCGCGCGTCTGCACA
ACATGACGCCGCTTGGCACGATGGCGCACGAGTACCTGCAGGCCTGCCAGGCCCTTGGGCCGCGCCTGCGTGATTCGCAG
GTCTACGCGCTGGAGCGGTGGGCACACGAGTATCGTGGTGACCTTGGCATCGCGCTTTCGGACACCTACGGCTTCGACGC
ATTCCTGCGGGACTTCGATCTCTATTTCTGCAAGCTGTTCGATGGCGTGCGACACGATTCGGGCGATCCGTTCGAATGGG
GCGAGCGGATGATCGCGCACTACGCAGCGAACCGCGTGGATCCGCGCGGCAAGACGCTGATCTTCAGCGATGCGCTGGAC
ATTCCCAAGGTCATCGAGCTCTATGAGCGATTCCGTGGCCGTTGCAAGCTCGCATTCGGTGTGGGCACCAACCTGACCAA
TGATCTTGGCTACAAGCCATTGCAGATCGTGATCAAGATGGTGCGCTGCAATGGGCAGCCCGTGGCCAAGCTGTCGGACA
CGCCCGAGAAGACGATGTGCGACGATCCCGGCTATCTGTCGTACCTGCGGCAGGTGTTCGCGGTTCAGGCCCCCGCTTAG

Upstream 100 bases:

>100_bases
GCCACAAGGACTGCGCTCGCTCGATGGCGGCTGACGACGCCAGGCCACGCCAGCGCGCCTCCGCGATACTTTCGGTTAGC
ATGATGGCCTGACTTCCGGT

Downstream 100 bases:

>100_bases
GAACTTTCAACCGCGCGCATCAGGACGCTTTCTACAATCGGTCTGCCCCTTCAACTGCCACATACTCACATCGCCATGGA
AACCAACGCCGCCCGTGACC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPPSGLVMIIRSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNAGVDLTPYVDEIRSQITQLCQLRFTDDELNYLRGLR
FIKSDFVEFLALFHLNEKYVQVLPSAKGNGEIEIIIKGPWLHTILFEIPLLAIVNEVYFRRTQPKPDLAEGRRRLQAKLE
LLAAPPYVDCVIADYGTRRRFSCDWQEEVLLSMRDAIGPQLAGTSNVHFARLHNMTPLGTMAHEYLQACQALGPRLRDSQ
VYALERWAHEYRGDLGIALSDTYGFDAFLRDFDLYFCKLFDGVRHDSGDPFEWGERMIAHYAANRVDPRGKTLIFSDALD
IPKVIELYERFRGRCKLAFGVGTNLTNDLGYKPLQIVIKMVRCNGQPVAKLSDTPEKTMCDDPGYLSYLRQVFAVQAPA

Sequences:

>Translated_399_residues
MPPSGLVMIIRSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNAGVDLTPYVDEIRSQITQLCQLRFTDDELNYLRGLR
FIKSDFVEFLALFHLNEKYVQVLPSAKGNGEIEIIIKGPWLHTILFEIPLLAIVNEVYFRRTQPKPDLAEGRRRLQAKLE
LLAAPPYVDCVIADYGTRRRFSCDWQEEVLLSMRDAIGPQLAGTSNVHFARLHNMTPLGTMAHEYLQACQALGPRLRDSQ
VYALERWAHEYRGDLGIALSDTYGFDAFLRDFDLYFCKLFDGVRHDSGDPFEWGERMIAHYAANRVDPRGKTLIFSDALD
IPKVIELYERFRGRCKLAFGVGTNLTNDLGYKPLQIVIKMVRCNGQPVAKLSDTPEKTMCDDPGYLSYLRQVFAVQAPA
>Mature_398_residues
PPSGLVMIIRSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNAGVDLTPYVDEIRSQITQLCQLRFTDDELNYLRGLRF
IKSDFVEFLALFHLNEKYVQVLPSAKGNGEIEIIIKGPWLHTILFEIPLLAIVNEVYFRRTQPKPDLAEGRRRLQAKLEL
LAAPPYVDCVIADYGTRRRFSCDWQEEVLLSMRDAIGPQLAGTSNVHFARLHNMTPLGTMAHEYLQACQALGPRLRDSQV
YALERWAHEYRGDLGIALSDTYGFDAFLRDFDLYFCKLFDGVRHDSGDPFEWGERMIAHYAANRVDPRGKTLIFSDALDI
PKVIELYERFRGRCKLAFGVGTNLTNDLGYKPLQIVIKMVRCNGQPVAKLSDTPEKTMCDDPGYLSYLRQVFAVQAPA

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=390, Percent_Identity=45.1282051282051, Blast_Score=338, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6324783, Length=402, Percent_Identity=31.3432835820896, Blast_Score=201, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45786; Mature: 45655

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSGLVMIIRSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNAGVDLTPYVDEIRSQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHH
TQLCQLRFTDDELNYLRGLRFIKSDFVEFLALFHLNEKYVQVLPSAKGNGEIEIIIKGPW
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEEECCH
LHTILFEIPLLAIVNEVYFRRTQPKPDLAEGRRRLQAKLELLAAPPYVDCVIADYGTRRR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
FSCDWQEEVLLSMRDAIGPQLAGTSNVHFARLHNMTPLGTMAHEYLQACQALGPRLRDSQ
CCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCH
VYALERWAHEYRGDLGIALSDTYGFDAFLRDFDLYFCKLFDGVRHDSGDPFEWGERMIAH
HHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YAANRVDPRGKTLIFSDALDIPKVIELYERFRGRCKLAFGVGTNLTNDLGYKPLQIVIKM
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHH
VRCNGQPVAKLSDTPEKTMCDDPGYLSYLRQVFAVQAPA
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPSGLVMIIRSLLDTDLYKFTMMQVVLHHFPQAQVEYRFKCRNAGVDLTPYVDEIRSQI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHH
TQLCQLRFTDDELNYLRGLRFIKSDFVEFLALFHLNEKYVQVLPSAKGNGEIEIIIKGPW
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEEECCH
LHTILFEIPLLAIVNEVYFRRTQPKPDLAEGRRRLQAKLELLAAPPYVDCVIADYGTRRR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
FSCDWQEEVLLSMRDAIGPQLAGTSNVHFARLHNMTPLGTMAHEYLQACQALGPRLRDSQ
CCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCH
VYALERWAHEYRGDLGIALSDTYGFDAFLRDFDLYFCKLFDGVRHDSGDPFEWGERMIAH
HHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YAANRVDPRGKTLIFSDALDIPKVIELYERFRGRCKLAFGVGTNLTNDLGYKPLQIVIKM
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHH
VRCNGQPVAKLSDTPEKTMCDDPGYLSYLRQVFAVQAPA
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA