Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 94311374

GI number: 94311374

Start: 2646193

End: 2646852

Strand: Reverse

Name: gph [C]

Synonym: Rmet_2438

Alternate gene names: 94311374

Gene position: 2646852-2646193 (Counterclockwise)

Preceding gene: 94311375

Following gene: 94311373

Centisome position: 67.38

GC content: 63.79

Gene sequence:

>660_bases
ATGGCCAGGCAGCGCTTCGACCTGATCGTCTTCGACTGGGATGGAACCCTGATGGATTCCACCCCGACCATCGCCAAATG
CATACAGCTCGCCAGCCGTGACCTGGGACTGCCAGTGCCGGATGACAGCGCGGCCAGCCATGTAATCGGACTCGGCCTGA
AAGACGCGCTCTCGTATGCAGTGCCGACGCTCGATCCCGCCGACTATCCGCGTCTGGCGGAACGCTACCGCTATCACTTC
CTGACGCGTGACGCCGAACTGGTGCTGTTTCCGGGCGTGCTCGACATGCTCGAGGCGCTTCACGCCGAGCATTACTTCCT
GGGCGTGGCCACCGGCAAGACCCGAGTCGGACTCGAACGTGCCCTGGCGGCAACTGGCATCGGCAAGCTGTTCGATGCTA
CGCGCTGCGCCGACGAGACGTTCTCGAAGCCGCATCCGGCCATGCTCCACGAACTGACGCGCGAACTTGGCCAGGATATC
GGTAGGACCGTGATGATCGGCGACACGACCCACGACCTGCAGATGGCCATCAACGCTGGCGCGCAGGGGCTTGGCGTCAC
CTACGGCGCGCATCCGGCGGAATCGCTGCGTGAGATGTCGCCTGTGCATTGCGCAACGTCGATTTCCGACCTGCAGGCCT
GGCTGCTCGCTCATGCCTGA

Upstream 100 bases:

>100_bases
CAACAATTGCGGCAAGGGCGACCAGCGCGCGACGCGGACTGATCCGTACGCACCATCGCTGTTAGCGCTCACACACTTTC
AGTATCCAACAAGGACCGCA

Downstream 100 bases:

>100_bases
AGCATCGCTGGAACCGCGGCGCCTTTGCGCGGCAGAGGAACTGGTCGACGGTGGCGCAGGTGTGCGCTTTGCCGTGCGTC
TCAACACGCGGGAGATCGGC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MARQRFDLIVFDWDGTLMDSTPTIAKCIQLASRDLGLPVPDDSAASHVIGLGLKDALSYAVPTLDPADYPRLAERYRYHF
LTRDAELVLFPGVLDMLEALHAEHYFLGVATGKTRVGLERALAATGIGKLFDATRCADETFSKPHPAMLHELTRELGQDI
GRTVMIGDTTHDLQMAINAGAQGLGVTYGAHPAESLREMSPVHCATSISDLQAWLLAHA

Sequences:

>Translated_219_residues
MARQRFDLIVFDWDGTLMDSTPTIAKCIQLASRDLGLPVPDDSAASHVIGLGLKDALSYAVPTLDPADYPRLAERYRYHF
LTRDAELVLFPGVLDMLEALHAEHYFLGVATGKTRVGLERALAATGIGKLFDATRCADETFSKPHPAMLHELTRELGQDI
GRTVMIGDTTHDLQMAINAGAQGLGVTYGAHPAESLREMSPVHCATSISDLQAWLLAHA
>Mature_218_residues
ARQRFDLIVFDWDGTLMDSTPTIAKCIQLASRDLGLPVPDDSAASHVIGLGLKDALSYAVPTLDPADYPRLAERYRYHFL
TRDAELVLFPGVLDMLEALHAEHYFLGVATGKTRVGLERALAATGIGKLFDATRCADETFSKPHPAMLHELTRELGQDIG
RTVMIGDTTHDLQMAINAGAQGLGVTYGAHPAESLREMSPVHCATSISDLQAWLLAHA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=226, Percent_Identity=30.9734513274336, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23823; Mature: 23692

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQRFDLIVFDWDGTLMDSTPTIAKCIQLASRDLGLPVPDDSAASHVIGLGLKDALSYA
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHH
VPTLDPADYPRLAERYRYHFLTRDAELVLFPGVLDMLEALHAEHYFLGVATGKTRVGLER
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHEEEEEECCCHHHHHHH
ALAATGIGKLFDATRCADETFSKPHPAMLHELTRELGQDIGRTVMIGDTTHDLQMAINAG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCC
AQGLGVTYGAHPAESLREMSPVHCATSISDLQAWLLAHA
CCCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARQRFDLIVFDWDGTLMDSTPTIAKCIQLASRDLGLPVPDDSAASHVIGLGLKDALSYA
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHH
VPTLDPADYPRLAERYRYHFLTRDAELVLFPGVLDMLEALHAEHYFLGVATGKTRVGLER
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHEEEEEECCCHHHHHHH
ALAATGIGKLFDATRCADETFSKPHPAMLHELTRELGQDIGRTVMIGDTTHDLQMAINAG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCC
AQGLGVTYGAHPAESLREMSPVHCATSISDLQAWLLAHA
CCCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA