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The map label for this gene is rseB [H]

Identifier: 94311359

GI number: 94311359

Start: 2633438

End: 2634517

Strand: Reverse

Name: rseB [H]

Synonym: Rmet_2423

Alternate gene names: 94311359

Gene position: 2634517-2633438 (Counterclockwise)

Preceding gene: 94311360

Following gene: 335055597

Centisome position: 67.07

GC content: 61.94

Gene sequence:

>1080_bases
ATGCATAAAGGACCGTCGCTCGCCAATGCAGCGGGCGTACACGGAAAGAAGGGCCTGCGGAGGTCCTTTTTTCTGGCCTT
ATGTCTGACCGCTGCCGCCGCGACTGCGCAGCCGTCTGACTCCACGCTGAACCGCCGTGACGCCACGGCGTGGCTGAACA
AGATCCATCGTGCTGCCCAGCGGGAGAACTACGTTGGTACGTTGATTTATCAGCGCGGCAGCATCATCCATGCCTCGCGG
ATCCAGCATTACAGTGATCTCGTACACAACGAGTACGAACGACTGGAAACGTTGGACGGCAAACCGCGCGAGGTGCTGCG
CCAGAATGATGTGGTTCACAGCCTGATTCCCGAGGCCAAGCTTGTGGTCGTGGAGAAGCAGGAGGCCAAGGACCGTTTCC
CGGCGCTGCTGGCGACGAACAAGAGCGACGTGCTCGACCTGTACGACATGCACAAGCTGCCGGCCGAACGTGTCGCCGGC
GTCGAGTGCGAGGTCTTCTCGCTGGACCCTCACGACACGGCACGTTACGCGGTGCGGTTGTGGGCCGACAGGAATTCGGG
CCTGCTGATGCGCGCGCAGACGATCGGCGAAGGCGGCAAGGTACTCGAGCAGGTCGCATTCTCGCAGGTCGATATCGGCG
TGCCTTCAGACAAGCAGCGCATCCTCAATGCGATCAAGGGCGCGAGCTCCTGGAGTCATTACGAGGTTACCTATCAGCCT
GCCAGCATCGCCGACGAAGGCTGGTCGATCAACACGCCAATCAAGGGCTTTCAGAAGATCCGGGAAGTGCGCCGCCCACT
GGGCGAGTTGCATGCCCCGACCTCGGCCAACAAGTCCGGGCAGGTCTTCGAAGTATTGCAGGTCGTCTACAGTGATGGCC
TGACGGGGCTTTCGGTCTTCATCGAGCCCGTATCCGAGCAGCGTGCCCGCCGCGAGGGCGTGGCGTCGCTAGGTGCCACC
CAGGTCGTGGTACGGCGCGTGGCCGATTTCTGGATTACCGTGGTCGGCGAAGTGCCTGCTTCTACGGTGAGGCAGTTTGC
GGCCGGCGTGGAATACCGCCCGCCCAAAGCGGTACACTGA

Upstream 100 bases:

>100_bases
ATCGCACGTCGGTCGCAACCGATGCCTTTGTGCCGACCATGCGTACGGTGGTGAATGGTGTCAACTTCTCTCAGGACAAT
TCGCAGGAATAATGCCGGAC

Downstream 100 bases:

>100_bases
CCGAAATTGGTCCGGCGGCGGTGGAGTGGCAGTCCCGCAACACCGCCAGGCAGTACGCTTTGCAGGCGTCCCCCGGCCTT
ATGCGCTGTGAAGCATCCGT

Product: anti-sigma factor, negative regulator of sigma24 activity

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MHKGPSLANAAGVHGKKGLRRSFFLALCLTAAAATAQPSDSTLNRRDATAWLNKIHRAAQRENYVGTLIYQRGSIIHASR
IQHYSDLVHNEYERLETLDGKPREVLRQNDVVHSLIPEAKLVVVEKQEAKDRFPALLATNKSDVLDLYDMHKLPAERVAG
VECEVFSLDPHDTARYAVRLWADRNSGLLMRAQTIGEGGKVLEQVAFSQVDIGVPSDKQRILNAIKGASSWSHYEVTYQP
ASIADEGWSINTPIKGFQKIREVRRPLGELHAPTSANKSGQVFEVLQVVYSDGLTGLSVFIEPVSEQRARREGVASLGAT
QVVVRRVADFWITVVGEVPASTVRQFAAGVEYRPPKAVH

Sequences:

>Translated_359_residues
MHKGPSLANAAGVHGKKGLRRSFFLALCLTAAAATAQPSDSTLNRRDATAWLNKIHRAAQRENYVGTLIYQRGSIIHASR
IQHYSDLVHNEYERLETLDGKPREVLRQNDVVHSLIPEAKLVVVEKQEAKDRFPALLATNKSDVLDLYDMHKLPAERVAG
VECEVFSLDPHDTARYAVRLWADRNSGLLMRAQTIGEGGKVLEQVAFSQVDIGVPSDKQRILNAIKGASSWSHYEVTYQP
ASIADEGWSINTPIKGFQKIREVRRPLGELHAPTSANKSGQVFEVLQVVYSDGLTGLSVFIEPVSEQRARREGVASLGAT
QVVVRRVADFWITVVGEVPASTVRQFAAGVEYRPPKAVH
>Mature_359_residues
MHKGPSLANAAGVHGKKGLRRSFFLALCLTAAAATAQPSDSTLNRRDATAWLNKIHRAAQRENYVGTLIYQRGSIIHASR
IQHYSDLVHNEYERLETLDGKPREVLRQNDVVHSLIPEAKLVVVEKQEAKDRFPALLATNKSDVLDLYDMHKLPAERVAG
VECEVFSLDPHDTARYAVRLWADRNSGLLMRAQTIGEGGKVLEQVAFSQVDIGVPSDKQRILNAIKGASSWSHYEVTYQP
ASIADEGWSINTPIKGFQKIREVRRPLGELHAPTSANKSGQVFEVLQVVYSDGLTGLSVFIEPVSEQRARREGVASLGAT
QVVVRRVADFWITVVGEVPASTVRQFAAGVEYRPPKAVH

Specific function: Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate- producing form. Inactivation of mucB causes conversion to mucoidy [H]

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family [H]

Homologues:

Organism=Escherichia coli, GI1788924, Length=328, Percent_Identity=25.609756097561, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005588 [H]

Pfam domain/function: PF03888 MucB_RseB [H]

EC number: NA

Molecular weight: Translated: 39687; Mature: 39687

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKGPSLANAAGVHGKKGLRRSFFLALCLTAAAATAQPSDSTLNRRDATAWLNKIHRAAQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RENYVGTLIYQRGSIIHASRIQHYSDLVHNEYERLETLDGKPREVLRQNDVVHSLIPEAK
HCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCE
LVVVEKQEAKDRFPALLATNKSDVLDLYDMHKLPAERVAGVECEVFSLDPHDTARYAVRL
EEEEECHHHHHHCCEEEECCCHHHHHHHHHHCCCHHHHCCCEEEEEECCCCHHHHEEEEE
WADRNSGLLMRAQTIGEGGKVLEQVAFSQVDIGVPSDKQRILNAIKGASSWSHYEVTYQP
EECCCCCEEEEEHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECC
ASIADEGWSINTPIKGFQKIREVRRPLGELHAPTSANKSGQVFEVLQVVYSDGLTGLSVF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
IEPVSEQRARREGVASLGATQVVVRRVADFWITVVGEVPASTVRQFAAGVEYRPPKAVH
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MHKGPSLANAAGVHGKKGLRRSFFLALCLTAAAATAQPSDSTLNRRDATAWLNKIHRAAQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RENYVGTLIYQRGSIIHASRIQHYSDLVHNEYERLETLDGKPREVLRQNDVVHSLIPEAK
HCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCE
LVVVEKQEAKDRFPALLATNKSDVLDLYDMHKLPAERVAGVECEVFSLDPHDTARYAVRL
EEEEECHHHHHHCCEEEECCCHHHHHHHHHHCCCHHHHCCCEEEEEECCCCHHHHEEEEE
WADRNSGLLMRAQTIGEGGKVLEQVAFSQVDIGVPSDKQRILNAIKGASSWSHYEVTYQP
EECCCCCEEEEEHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECC
ASIADEGWSINTPIKGFQKIREVRRPLGELHAPTSANKSGQVFEVLQVVYSDGLTGLSVF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
IEPVSEQRARREGVASLGATQVVVRRVADFWITVVGEVPASTVRQFAAGVEYRPPKAVH
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412698; 8378309; 8444793; 10984043 [H]