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The map label for this gene is blh [H]

Identifier: 94311309

GI number: 94311309

Start: 2583983

End: 2585653

Strand: Direct

Name: blh [H]

Synonym: Rmet_2373

Alternate gene names: 94311309

Gene position: 2583983-2585653 (Clockwise)

Preceding gene: 94311308

Following gene: 94311310

Centisome position: 65.78

GC content: 67.56

Gene sequence:

>1671_bases
ATGGACATCAAAGCCTTGGACCAGGGACTGGCCGTCAGCGGCCAGATCGCTGCCACCGACCTGCAGGCCATCGCCGAGGC
TGGCTACCGCTCGGTGATCTGCAATCGGCCCGATGGAGAAGCGGGCGATCAGCCCGGCTTCAGCGAAATCGAGCAGGCCG
CCCAGTCACTGGGTATGGCGGCGACCTACCTGCCCGTCGAGTCCGGCAAAGTGACCGACCAGCAGGCCCAGGCCTTCGGG
ACGCTGATGACGCAACTGCCCGGCCCGGTGTTCGCCTACTGCCGCACCGGCACGCGCTCGGCCACGCTGTGGGCGCTGAG
CCAGGCGCAGCGTCAGCCGTTGGCCTCCATCCTCGAAGCCGCGCGCGGTGCCGGCTACGACCTGTCCGGCGTGGCCCGGC
GCATCGCCAACGGCGGGCGCACACCCACCGAAGTCGTGGACGCCACGCATGACATCGTGATCGTCGGCGCGGGCGCGGCG
GGCATCGCGGTGGCGTCCAGCCTGCTCGCGCGCAAGCCGGACGCGGACATCGCCGTCATCGACCCGGCGGATGTGCACTA
CTACCAGCCGGGGTGGACGATGGTGGGCGCGGGCATCTTTCCGCCTGCGCACACGGCGCGCACGATGGCGAGCGTGCTTC
CGCGCGGCGTCAAGTGGATCAAGATGGCCGTCGCCGCGTTCGAGCCCGAGCGCGACGCCCTCGTGCTCGATGGCTGCCGC
GTCGTCAAGTACCAGCAGCTCGTGGTCTGCCCGGGCCTGAAACTCGACTGGAACGGCATCGAGGGCCTACCTGAAACACT
GGGCCGCAACGGCGTCACCTCCAACTACCGCTACGACCTCGCGCCCTACACCTGGGAACTGGTGCAGAACCTCAAGAGCG
GCCAGGCCCTGTTCACGCAGCCGCCCATGCCCATCAAATGCGCGGGTGCGCCGCAGAAGGCGATGTACCTCTCGGCCGAT
CACTGGAAGCGGCAGGGCGTGCTCAAGAACATCCACATCGAGTTCTGCAACGCGGGAGGCGTGCTCTTCGGCGTGCCGGA
CTACGTGCCCGCGCTCATGGAGTACGTGAAGGCTTATGGCATCGATCTGCAATTCAGCAACCAGCTCGTGGCCGTCGATG
GCGCAGCGCATGAAGCCACCTTCATCCGCACGAACGCCGACGGCACCAAGGAGCGCGTCACCCGTCCATTTGACCTGCTG
CACGCCGTGCCGCCACAGAAGGCGCCGGACTTCATCCGAGTGAGCCCGCTGGCGGACGCTGCGGGCTGGGTGGACGTGGA
CCCGTCGAGCCTGCGCCACAAGAAGTACGCCAACGTCTTCGCACTCGGCGACTGCACCAACACCACCAATGCCAAGACTG
CTGCGGCCGCACGCAAGCAGGCGCCGGTGGTCGCGCACAACCTGCTCGCCGCCCGGAGCGGGTCCACGCGCCTGGCCAGC
TATGACGGCTATGGCTCCTGCCCGCTCACTGTCGAGCGCGGCAAGATCGTGCTGGCGGAATTTGCCTACGGCGGCAAGCT
GGCGCCTTCGTTTCCGAAATGGTTCATCGACGGCAAGCGGCCGTCATCGCTGGCGTGGCTGCTGAAGGAACGCATCCTGC
CGCCGGTCTATTGGGACGGCATGCTCAAGGGCCGCGAATGGCTCGCGCATCCTGTCCTCTCGGACGGGTGA

Upstream 100 bases:

>100_bases
TGCCGAATCCAACGGCGTCCACTACCTCAAGATTCCCATCGATGCCCTCTGAGAGCGGCACCGACCGGCTGAAAGGACAA
TTTCCGGGCAGGAGACCCTC

Downstream 100 bases:

>100_bases
GCCGCCGCATGCGTCATCGCCGGGACATGGGAAACCGACGCTCATAGTGCGGGCGAAAGGAGGAGCGGCATTCGGCCCTC
CGAGCCTCAACAGCGGCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MDIKALDQGLAVSGQIAATDLQAIAEAGYRSVICNRPDGEAGDQPGFSEIEQAAQSLGMAATYLPVESGKVTDQQAQAFG
TLMTQLPGPVFAYCRTGTRSATLWALSQAQRQPLASILEAARGAGYDLSGVARRIANGGRTPTEVVDATHDIVIVGAGAA
GIAVASSLLARKPDADIAVIDPADVHYYQPGWTMVGAGIFPPAHTARTMASVLPRGVKWIKMAVAAFEPERDALVLDGCR
VVKYQQLVVCPGLKLDWNGIEGLPETLGRNGVTSNYRYDLAPYTWELVQNLKSGQALFTQPPMPIKCAGAPQKAMYLSAD
HWKRQGVLKNIHIEFCNAGGVLFGVPDYVPALMEYVKAYGIDLQFSNQLVAVDGAAHEATFIRTNADGTKERVTRPFDLL
HAVPPQKAPDFIRVSPLADAAGWVDVDPSSLRHKKYANVFALGDCTNTTNAKTAAAARKQAPVVAHNLLAARSGSTRLAS
YDGYGSCPLTVERGKIVLAEFAYGGKLAPSFPKWFIDGKRPSSLAWLLKERILPPVYWDGMLKGREWLAHPVLSDG

Sequences:

>Translated_556_residues
MDIKALDQGLAVSGQIAATDLQAIAEAGYRSVICNRPDGEAGDQPGFSEIEQAAQSLGMAATYLPVESGKVTDQQAQAFG
TLMTQLPGPVFAYCRTGTRSATLWALSQAQRQPLASILEAARGAGYDLSGVARRIANGGRTPTEVVDATHDIVIVGAGAA
GIAVASSLLARKPDADIAVIDPADVHYYQPGWTMVGAGIFPPAHTARTMASVLPRGVKWIKMAVAAFEPERDALVLDGCR
VVKYQQLVVCPGLKLDWNGIEGLPETLGRNGVTSNYRYDLAPYTWELVQNLKSGQALFTQPPMPIKCAGAPQKAMYLSAD
HWKRQGVLKNIHIEFCNAGGVLFGVPDYVPALMEYVKAYGIDLQFSNQLVAVDGAAHEATFIRTNADGTKERVTRPFDLL
HAVPPQKAPDFIRVSPLADAAGWVDVDPSSLRHKKYANVFALGDCTNTTNAKTAAAARKQAPVVAHNLLAARSGSTRLAS
YDGYGSCPLTVERGKIVLAEFAYGGKLAPSFPKWFIDGKRPSSLAWLLKERILPPVYWDGMLKGREWLAHPVLSDG
>Mature_556_residues
MDIKALDQGLAVSGQIAATDLQAIAEAGYRSVICNRPDGEAGDQPGFSEIEQAAQSLGMAATYLPVESGKVTDQQAQAFG
TLMTQLPGPVFAYCRTGTRSATLWALSQAQRQPLASILEAARGAGYDLSGVARRIANGGRTPTEVVDATHDIVIVGAGAA
GIAVASSLLARKPDADIAVIDPADVHYYQPGWTMVGAGIFPPAHTARTMASVLPRGVKWIKMAVAAFEPERDALVLDGCR
VVKYQQLVVCPGLKLDWNGIEGLPETLGRNGVTSNYRYDLAPYTWELVQNLKSGQALFTQPPMPIKCAGAPQKAMYLSAD
HWKRQGVLKNIHIEFCNAGGVLFGVPDYVPALMEYVKAYGIDLQFSNQLVAVDGAAHEATFIRTNADGTKERVTRPFDLL
HAVPPQKAPDFIRVSPLADAAGWVDVDPSSLRHKKYANVFALGDCTNTTNAKTAAAARKQAPVVAHNLLAARSGSTRLAS
YDGYGSCPLTVERGKIVLAEFAYGGKLAPSFPKWFIDGKRPSSLAWLLKERILPPVYWDGMLKGREWLAHPVLSDG

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI10864011, Length=395, Percent_Identity=36.4556962025316, Blast_Score=296, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17539680, Length=430, Percent_Identity=32.7906976744186, Blast_Score=235, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI115534373, Length=341, Percent_Identity=36.3636363636364, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24657386, Length=385, Percent_Identity=35.8441558441558, Blast_Score=249, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24657391, Length=385, Percent_Identity=35.8441558441558, Blast_Score=249, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 59639; Mature: 59639

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKALDQGLAVSGQIAATDLQAIAEAGYRSVICNRPDGEAGDQPGFSEIEQAAQSLGMA
CCCHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCE
ATYLPVESGKVTDQQAQAFGTLMTQLPGPVFAYCRTGTRSATLWALSQAQRQPLASILEA
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCHHHHHHHH
ARGAGYDLSGVARRIANGGRTPTEVVDATHDIVIVGAGAAGIAVASSLLARKPDADIAVI
HCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEE
DPADVHYYQPGWTMVGAGIFPPAHTARTMASVLPRGVKWIKMAVAAFEPERDALVLDGCR
CCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCE
VVKYQQLVVCPGLKLDWNGIEGLPETLGRNGVTSNYRYDLAPYTWELVQNLKSGQALFTQ
EEEEEEEEECCCCEECCCCCCCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCEEEEC
PPMPIKCAGAPQKAMYLSADHWKRQGVLKNIHIEFCNAGGVLFGVPDYVPALMEYVKAYG
CCCCEEECCCCCCEEEEEHHHHHHCCCEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHC
IDLQFSNQLVAVDGAAHEATFIRTNADGTKERVTRPFDLLHAVPPQKAPDFIRVSPLADA
CCEEECCEEEEECCCCCCEEEEEECCCCCHHHHCCHHHHHHCCCCCCCCCCEEECCCCCC
AGWVDVDPSSLRHKKYANVFALGDCTNTTNAKTAAAARKQAPVVAHNLLAARSGSTRLAS
CCEEECCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEE
YDGYGSCPLTVERGKIVLAEFAYGGKLAPSFPKWFIDGKRPSSLAWLLKERILPPVYWDG
CCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHCC
MLKGREWLAHPVLSDG
HHCCHHHHHCCCCCCC
>Mature Secondary Structure
MDIKALDQGLAVSGQIAATDLQAIAEAGYRSVICNRPDGEAGDQPGFSEIEQAAQSLGMA
CCCHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCE
ATYLPVESGKVTDQQAQAFGTLMTQLPGPVFAYCRTGTRSATLWALSQAQRQPLASILEA
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCHHHHHHHH
ARGAGYDLSGVARRIANGGRTPTEVVDATHDIVIVGAGAAGIAVASSLLARKPDADIAVI
HCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEE
DPADVHYYQPGWTMVGAGIFPPAHTARTMASVLPRGVKWIKMAVAAFEPERDALVLDGCR
CCCCCEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCE
VVKYQQLVVCPGLKLDWNGIEGLPETLGRNGVTSNYRYDLAPYTWELVQNLKSGQALFTQ
EEEEEEEEECCCCEECCCCCCCCHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCEEEEC
PPMPIKCAGAPQKAMYLSADHWKRQGVLKNIHIEFCNAGGVLFGVPDYVPALMEYVKAYG
CCCCEEECCCCCCEEEEEHHHHHHCCCEEEEEEEEECCCCEEEECHHHHHHHHHHHHHHC
IDLQFSNQLVAVDGAAHEATFIRTNADGTKERVTRPFDLLHAVPPQKAPDFIRVSPLADA
CCEEECCEEEEECCCCCCEEEEEECCCCCHHHHCCHHHHHHCCCCCCCCCCEEECCCCCC
AGWVDVDPSSLRHKKYANVFALGDCTNTTNAKTAAAARKQAPVVAHNLLAARSGSTRLAS
CCEEECCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEE
YDGYGSCPLTVERGKIVLAEFAYGGKLAPSFPKWFIDGKRPSSLAWLLKERILPPVYWDG
CCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHCC
MLKGREWLAHPVLSDG
HHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]