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The map label for this gene is argAB [H]

Identifier: 94311008

GI number: 94311008

Start: 2245575

End: 2247011

Strand: Direct

Name: argAB [H]

Synonym: Rmet_2070

Alternate gene names: 94311008

Gene position: 2245575-2247011 (Clockwise)

Preceding gene: 94311001

Following gene: 94311009

Centisome position: 57.17

GC content: 65.34

Gene sequence:

>1437_bases
ATGAACGCCAGAACCGACTCCCCGCAGCAGGACCCCGATCCTGCCTCCGCCCCGCTCCCGCTGCCCGTAAAGGCCGCGCC
CGACACCCAGAATCCGCCCGTCGCCACGGAGCTTGCCGAGCCCGCCGGCCCGGACCAGCAGCAGTTCGTCGACTGGCTGC
GATCGGTCGCGCCCTATATCCATGCCTTCCGCGGCAAGACGTTCGTAATCGCCTTCAGCGGCGAACTGGTCAAGGCCGGG
GTGCTCAACGGACTGGTCAATGACGTGGCGCTGCTGCACGCGATGGGCATGCAGATCGTGCTGGTGTTCGGATCCCGACC
GCAGGTGGAAGAACAGCTCGCGCTGCGCAATGTCCAGTCGCAGTACGCGGAAGGCATCCGAATCACCGACAATGCCGCGC
TGGAATGCGCCAAGGAAGCCGCCGGCGAGTTGCGCCTCGACATTGAGGCCGCGTTCAGCCAGGGACTGCCGAACACGCCG
ATGGCTGGCGCCCAGCTTTCCGTGGTGTCGGGCAACTTCATCACCGCGCGCCCGGTGGGCATCGTCAATGGCGTGGACTA
TCAGCACACCGGTCTGGTCCGCAAGATCGACGGCGACTCGATGCGCATGTCGCTATCGCACGGCAAGGTGGTGCTGCTGT
CGCCGCTCGGCTTCTCGCCGACCGGCCAGGCATTCAACCTGTCAATGGAGGACGTGGCCAGCGCCACGGCCAGCGCGCTC
AAGGCGGACAAGCTGATCTTCATCACCGAGGTACCCGGCGTGCCCGACCAGGTGGGCAAGCTGATGAAGGAAATGTCGCT
GCGCACCGCCGTGGAACGGCTGCAGAACAACCACCTGCCACCCGACGTCGCGTACTACCTCCAGCATCTGGTCAAAGCGC
TCAAGGGCGGCGTGCCGCGCGCGCACCTGATCCCGTTCTCGCTGGACGGTTCGGTGCTGCTGGAGCTGTTCCTGCACGAC
GGCGTGGGCACCATGCTGTCCGACAGCGATCTGGAAAGCCTGCGTGAAGCCACGCTTGACGACGTTGGCGGCATTCTGCA
GCTCATCGCCCCGCTTGAGGCCGATGGCACGCTGGTTCCCCGTGGCCGCCATCTGATCGAGCGCGACATCGACAAGTTCT
CGGTGATCGAGCACGATGGCGTGCTGTTCGGCTGCGCCGCGCTCTACGAATTTCCACGCGAGAACATGGGCGAGATGGCC
TGCCTGACCGTATCGCAGGAAGCCCAGGGCACCGGCGACGGCGAACGGCTGCTCAAGCGGATCGAGCGCCGCGCCCGCGC
GCTGGGCCTGGAACGCCTGTTCGTGCTCACCACGCGTACCGAACACTGGTTCCTCAAGCGTGGGTTCGTCCACGCCACGG
TCGACGATCTGCCCGAAGACAAGCGCAAGCTCTACAACTGGCAGCGCAAGTCGATGGTCCTGATGAAGAAGCTCTGA

Upstream 100 bases:

>100_bases
GGATTCGGAGGGACCGGGGAAGTCTTGGCCTCGGCGGGCCGGGACGGAACAGGTTTGGCGGGGCGTTGTGCTGACATTGG
CCGGGATTATAATCCGCCGC

Downstream 100 bases:

>100_bases
CGCGGCAGTAACAACAAGGTCGGCAGGGGCATGGGCGGATACTCCCGCCCGGCCGGCCAGCTTGGCTACAATAGCGGCCA
AACGAACAAGGAGTCCCTCA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MNARTDSPQQDPDPASAPLPLPVKAAPDTQNPPVATELAEPAGPDQQQFVDWLRSVAPYIHAFRGKTFVIAFSGELVKAG
VLNGLVNDVALLHAMGMQIVLVFGSRPQVEEQLALRNVQSQYAEGIRITDNAALECAKEAAGELRLDIEAAFSQGLPNTP
MAGAQLSVVSGNFITARPVGIVNGVDYQHTGLVRKIDGDSMRMSLSHGKVVLLSPLGFSPTGQAFNLSMEDVASATASAL
KADKLIFITEVPGVPDQVGKLMKEMSLRTAVERLQNNHLPPDVAYYLQHLVKALKGGVPRAHLIPFSLDGSVLLELFLHD
GVGTMLSDSDLESLREATLDDVGGILQLIAPLEADGTLVPRGRHLIERDIDKFSVIEHDGVLFGCAALYEFPRENMGEMA
CLTVSQEAQGTGDGERLLKRIERRARALGLERLFVLTTRTEHWFLKRGFVHATVDDLPEDKRKLYNWQRKSMVLMKKL

Sequences:

>Translated_478_residues
MNARTDSPQQDPDPASAPLPLPVKAAPDTQNPPVATELAEPAGPDQQQFVDWLRSVAPYIHAFRGKTFVIAFSGELVKAG
VLNGLVNDVALLHAMGMQIVLVFGSRPQVEEQLALRNVQSQYAEGIRITDNAALECAKEAAGELRLDIEAAFSQGLPNTP
MAGAQLSVVSGNFITARPVGIVNGVDYQHTGLVRKIDGDSMRMSLSHGKVVLLSPLGFSPTGQAFNLSMEDVASATASAL
KADKLIFITEVPGVPDQVGKLMKEMSLRTAVERLQNNHLPPDVAYYLQHLVKALKGGVPRAHLIPFSLDGSVLLELFLHD
GVGTMLSDSDLESLREATLDDVGGILQLIAPLEADGTLVPRGRHLIERDIDKFSVIEHDGVLFGCAALYEFPRENMGEMA
CLTVSQEAQGTGDGERLLKRIERRARALGLERLFVLTTRTEHWFLKRGFVHATVDDLPEDKRKLYNWQRKSMVLMKKL
>Mature_478_residues
MNARTDSPQQDPDPASAPLPLPVKAAPDTQNPPVATELAEPAGPDQQQFVDWLRSVAPYIHAFRGKTFVIAFSGELVKAG
VLNGLVNDVALLHAMGMQIVLVFGSRPQVEEQLALRNVQSQYAEGIRITDNAALECAKEAAGELRLDIEAAFSQGLPNTP
MAGAQLSVVSGNFITARPVGIVNGVDYQHTGLVRKIDGDSMRMSLSHGKVVLLSPLGFSPTGQAFNLSMEDVASATASAL
KADKLIFITEVPGVPDQVGKLMKEMSLRTAVERLQNNHLPPDVAYYLQHLVKALKGGVPRAHLIPFSLDGSVLLELFLHD
GVGTMLSDSDLESLREATLDDVGGILQLIAPLEADGTLVPRGRHLIERDIDKFSVIEHDGVLFGCAALYEFPRENMGEMA
CLTVSQEAQGTGDGERLLKRIERRARALGLERLFVLTTRTEHWFLKRGFVHATVDDLPEDKRKLYNWQRKSMVLMKKL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=437, Percent_Identity=44.8512585812357, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6320913, Length=280, Percent_Identity=21.7857142857143, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 52160; Mature: 52160

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARTDSPQQDPDPASAPLPLPVKAAPDTQNPPVATELAEPAGPDQQQFVDWLRSVAPYI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
HAFRGKTFVIAFSGELVKAGVLNGLVNDVALLHAMGMQIVLVFGSRPQVEEQLALRNVQS
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHH
QYAEGIRITDNAALECAKEAAGELRLDIEAAFSQGLPNTPMAGAQLSVVSGNFITARPVG
HHHCCEEEECHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCCCCCEEEEEECCEEEECCCE
IVNGVDYQHTGLVRKIDGDSMRMSLSHGKVVLLSPLGFSPTGQAFNLSMEDVASATASAL
EECCCCCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHH
KADKLIFITEVPGVPDQVGKLMKEMSLRTAVERLQNNHLPPDVAYYLQHLVKALKGGVPR
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
AHLIPFSLDGSVLLELFLHDGVGTMLSDSDLESLREATLDDVGGILQLIAPLEADGTLVP
EEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RGRHLIERDIDKFSVIEHDGVLFGCAALYEFPRENMGEMACLTVSQEAQGTGDGERLLKR
CCHHHHHHCCHHHHEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
IERRARALGLERLFVLTTRTEHWFLKRGFVHATVDDLPEDKRKLYNWQRKSMVLMKKL
HHHHHHHHCCCEEEEEEECCHHHHHHCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNARTDSPQQDPDPASAPLPLPVKAAPDTQNPPVATELAEPAGPDQQQFVDWLRSVAPYI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
HAFRGKTFVIAFSGELVKAGVLNGLVNDVALLHAMGMQIVLVFGSRPQVEEQLALRNVQS
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHH
QYAEGIRITDNAALECAKEAAGELRLDIEAAFSQGLPNTPMAGAQLSVVSGNFITARPVG
HHHCCEEEECHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCCCCCEEEEEECCEEEECCCE
IVNGVDYQHTGLVRKIDGDSMRMSLSHGKVVLLSPLGFSPTGQAFNLSMEDVASATASAL
EECCCCCCCCCCEEEECCCCEEEEECCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHH
KADKLIFITEVPGVPDQVGKLMKEMSLRTAVERLQNNHLPPDVAYYLQHLVKALKGGVPR
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
AHLIPFSLDGSVLLELFLHDGVGTMLSDSDLESLREATLDDVGGILQLIAPLEADGTLVP
EEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RGRHLIERDIDKFSVIEHDGVLFGCAALYEFPRENMGEMACLTVSQEAQGTGDGERLLKR
CCHHHHHHCCHHHHEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
IERRARALGLERLFVLTTRTEHWFLKRGFVHATVDDLPEDKRKLYNWQRKSMVLMKKL
HHHHHHHHCCCEEEEEEECCHHHHHHCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]