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The map label for this gene is erg3 [H]

Identifier: 94310961

GI number: 94310961

Start: 2187080

End: 2188048

Strand: Direct

Name: erg3 [H]

Synonym: Rmet_2023

Alternate gene names: 94310961

Gene position: 2187080-2188048 (Clockwise)

Preceding gene: 94310958

Following gene: 94310963

Centisome position: 55.68

GC content: 61.51

Gene sequence:

>969_bases
ATGCGTATGGAGGAATCCCTCCATGCGAAACTGCGAAAAATATGCACACTGTCGCCCATGACACCGCAAACCCCTGCCCC
CGAGGCGTTCGATCCCGGCCTGATTCTCCTGGCCTTTGCGCCGGTCTTCGTGCTGACGATAGGTTGGGAAGCCTGGTACT
GGTGGAAGCGCGATCGCTCGGTCTATAGCTGGCGCGACACGCTCTCGAATGCCACGCTCGCACTGATGCATCAGGCATCC
GATGCGCTGTTTCTCTGGCTGATGGTTCGCACGGTCTACACGTGGTGCTACGCCCACGGGCTTCGTGCGGTGCCGGAGAC
CTGGTGGTCGTTCGCGCTGCTATTGATCTTGCAGGACTTCCTCTACTACTGGTTCCATCGTGCCAGCCACCAGGTGCGCT
GGATGTGGGCTTCGCACGTGGCGCATCACTCGTCGGAGGGCATGAACTTCTCGACGGCTTTCCGGCAGAGCCTGACCTAC
CCGATCTCCGGCATGTGGATTTTCTGGATCCCTCTGGCACTCGTCGGCTTCACGCCTGACTGGGTGATCCTTGCAGTGGG
ACTGAACCTGGCGTTTCAGTTTTTCGTGCACACGCGACTGGGGCGACGCTGGCCGCTGGTTGAGAGACTCGTCAACACGC
CATCGGTCCATCGCGTCCACCATGCGAAGAATCCTCAATACATCGACCGCAACTACGCCGGGGTTCTGACGATCTGGGAC
CGGATGTTCGGCACCTTCGTGCCCGAAGAGGAAGCGCCGCAGTACGGCATTACGCGGCAGGTCTGCACCTACAACCCGCT
GACGCTGACATTCCACGAATGGCGCGACATGTTTGCCGATGCCTGGCGCGAGCGTGACCCACGATACCTGTGGAAGCCGC
CCGAGTGGCGCAGCCCTCGATCCGCATTGATGCCCAGCGCGGGCCAAACGCCCGCTGCCGAGCACGGACAGCGCTCCGAC
GCGATCTGA

Upstream 100 bases:

>100_bases
AAACTCCGTCATTTCTGTCTCCATCATTGCAGGCAGCGATTCTACGACAGACCCGCCAAAGCGCCTGCCACGGCACAACA
CGGGAAACCCCGATGCGCGT

Downstream 100 bases:

>100_bases
TACGAACCTGCGCACTTGGAGACGGCAAGCGCCCATAAAAAAACCGCGCCACACCGGGCGCGGTTTTTTCTTCAAGCGGA
TGCCTGTCAGGCCACCGATT

Product: sterol desaturase family protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRMEESLHAKLRKICTLSPMTPQTPAPEAFDPGLILLAFAPVFVLTIGWEAWYWWKRDRSVYSWRDTLSNATLALMHQAS
DALFLWLMVRTVYTWCYAHGLRAVPETWWSFALLLILQDFLYYWFHRASHQVRWMWASHVAHHSSEGMNFSTAFRQSLTY
PISGMWIFWIPLALVGFTPDWVILAVGLNLAFQFFVHTRLGRRWPLVERLVNTPSVHRVHHAKNPQYIDRNYAGVLTIWD
RMFGTFVPEEEAPQYGITRQVCTYNPLTLTFHEWRDMFADAWRERDPRYLWKPPEWRSPRSALMPSAGQTPAAEHGQRSD
AI

Sequences:

>Translated_322_residues
MRMEESLHAKLRKICTLSPMTPQTPAPEAFDPGLILLAFAPVFVLTIGWEAWYWWKRDRSVYSWRDTLSNATLALMHQAS
DALFLWLMVRTVYTWCYAHGLRAVPETWWSFALLLILQDFLYYWFHRASHQVRWMWASHVAHHSSEGMNFSTAFRQSLTY
PISGMWIFWIPLALVGFTPDWVILAVGLNLAFQFFVHTRLGRRWPLVERLVNTPSVHRVHHAKNPQYIDRNYAGVLTIWD
RMFGTFVPEEEAPQYGITRQVCTYNPLTLTFHEWRDMFADAWRERDPRYLWKPPEWRSPRSALMPSAGQTPAAEHGQRSD
AI
>Mature_322_residues
MRMEESLHAKLRKICTLSPMTPQTPAPEAFDPGLILLAFAPVFVLTIGWEAWYWWKRDRSVYSWRDTLSNATLALMHQAS
DALFLWLMVRTVYTWCYAHGLRAVPETWWSFALLLILQDFLYYWFHRASHQVRWMWASHVAHHSSEGMNFSTAFRQSLTY
PISGMWIFWIPLALVGFTPDWVILAVGLNLAFQFFVHTRLGRRWPLVERLVNTPSVHRVHHAKNPQYIDRNYAGVLTIWD
RMFGTFVPEEEAPQYGITRQVCTYNPLTLTFHEWRDMFADAWRERDPRYLWKPPEWRSPRSALMPSAGQTPAAEHGQRSD
AI

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=216, Percent_Identity=41.6666666666667, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI25144659, Length=188, Percent_Identity=38.2978723404255, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 37915; Mature: 37915

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMEESLHAKLRKICTLSPMTPQTPAPEAFDPGLILLAFAPVFVLTIGWEAWYWWKRDRS
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCC
VYSWRDTLSNATLALMHQASDALFLWLMVRTVYTWCYAHGLRAVPETWWSFALLLILQDF
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LYYWFHRASHQVRWMWASHVAHHSSEGMNFSTAFRQSLTYPISGMWIFWIPLALVGFTPD
HHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
WVILAVGLNLAFQFFVHTRLGRRWPLVERLVNTPSVHRVHHAKNPQYIDRNYAGVLTIWD
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHH
RMFGTFVPEEEAPQYGITRQVCTYNPLTLTFHEWRDMFADAWRERDPRYLWKPPEWRSPR
HHHHCCCCCCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
SALMPSAGQTPAAEHGQRSDAI
HHHCCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MRMEESLHAKLRKICTLSPMTPQTPAPEAFDPGLILLAFAPVFVLTIGWEAWYWWKRDRS
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCC
VYSWRDTLSNATLALMHQASDALFLWLMVRTVYTWCYAHGLRAVPETWWSFALLLILQDF
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LYYWFHRASHQVRWMWASHVAHHSSEGMNFSTAFRQSLTYPISGMWIFWIPLALVGFTPD
HHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
WVILAVGLNLAFQFFVHTRLGRRWPLVERLVNTPSVHRVHHAKNPQYIDRNYAGVLTIWD
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHH
RMFGTFVPEEEAPQYGITRQVCTYNPLTLTFHEWRDMFADAWRERDPRYLWKPPEWRSPR
HHHHCCCCCCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
SALMPSAGQTPAAEHGQRSDAI
HHHCCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]