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The map label for this gene is paaG [C]

Identifier: 94310960

GI number: 94310960

Start: 2185909

End: 2187060

Strand: Reverse

Name: paaG [C]

Synonym: Rmet_2022

Alternate gene names: 94310960

Gene position: 2187060-2185909 (Counterclockwise)

Preceding gene: 94310962

Following gene: 94310959

Centisome position: 55.68

GC content: 63.02

Gene sequence:

>1152_bases
GTGTTGTGCCGTGGCAGGCGCTTTGGCGGGTCTGTCGTAGAATCGCTGCCTGCAATGATGGAGACAGAAATGACGGAGTT
TGTATCGACCCAGGTGCAGGGCGGCGTGGCGTATCTGACACTGACCCGGCCGCAGGCCCTCAACGCGCTGTCGCTCGAGA
TGATTCGCGCGATCACCGGTGCGCTGCAAAGCTGGGAGAACGATCCCGCAGTCCACGCGATGGTAGTGGCTGGCGCGGGC
GGCAAGGCATTCTGCGCCGGCGGCGATATCCGCTGGTTCTACCAGGCGCACCAGGCGAACGATCCGCTGCTGGATCAGTT
CTTCGTTGAGGAATACGCGCTCAACCATCTGATTCATCGCTATGCCAAGCCTTACATCGCGCTGATGGATGGCGTGGTCA
TGGGCGGTGGTATGGGGATCTCGCAGGGCGCGCGGCTGCGCATCGTCACCGAGCGGACGAAAATGGCGATGCCGGAGACC
AATATCGGTCTGTTCCCCGATGTTGGCGGTGGATGGTTCCTGGCACGCACGCAAGGTCATATCGGCGAGTACCTGGGCCT
TACCGGCGCGGTGATCGGCGCGGCCGATGCTATTTACGCGAAGCTGGCCGATGCCTATCTGCCAACGAACGCGATCGCCG
AGATGGTTGCATCGCTGCAGGCGCGGCAGTTCACCAGTGGCGAAGCGGTACTCGAGCAGATTGCGTCGTTCACGCGCCAG
CACGCCGACGCCTGCGTACCATCCACCAGCCAGCTGGCTTCGAATGCTGCCCTGATCGATACCTTGTTCGCAGGCGCCTC
CGCACAGGCGATCCTGGCAGCTGTCAGCGACGCCGAAGGCGATTGGGCCGCGCAAACCGCCGCCACGCTGCGTAGCCGCT
CACCGCTGATGCTCTGCGTCACGCTCGAACAGATCCGCCGTGCTCGCACGATGTCGCTCGAAGATGAGCTGCGGATGGAG
CTCGACATGATGCATGACGTGTTCCGTCACGGCGACGGCATCGAGGGAATTCGCGCGCTGGTGATCGACAAGGACCACCA
GCCGAAGTGGAATCCGCCACGCCTGGACGAGGTGAGTGGGGCACGCGTGCGTGCGTTCTTCGATAGTCCATGGCGCAAGG
ATGACCATCCCTTGGCTACGCTGGGCGCGTAA

Upstream 100 bases:

>100_bases
GGGGGCAGGGGTTTGCGGTGTCATGGGCGACAGTGTGCATATTTTTCGCAGTTTCGCATGGAGGGATTCCTCCATACGCA
TACGCGCATCGGGGTTTCCC

Downstream 100 bases:

>100_bases
GTCGAGTAGAGTGTCGGCTGGACTGGCCCGCAGCGTTGTCGCGGACCAGGCTTCTCTTCGTTCGAACTCGTTCAAGCAGT
GAAAGGAACCGTTATGAGCA

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MLCRGRRFGGSVVESLPAMMETEMTEFVSTQVQGGVAYLTLTRPQALNALSLEMIRAITGALQSWENDPAVHAMVVAGAG
GKAFCAGGDIRWFYQAHQANDPLLDQFFVEEYALNHLIHRYAKPYIALMDGVVMGGGMGISQGARLRIVTERTKMAMPET
NIGLFPDVGGGWFLARTQGHIGEYLGLTGAVIGAADAIYAKLADAYLPTNAIAEMVASLQARQFTSGEAVLEQIASFTRQ
HADACVPSTSQLASNAALIDTLFAGASAQAILAAVSDAEGDWAAQTAATLRSRSPLMLCVTLEQIRRARTMSLEDELRME
LDMMHDVFRHGDGIEGIRALVIDKDHQPKWNPPRLDEVSGARVRAFFDSPWRKDDHPLATLGA

Sequences:

>Translated_383_residues
MLCRGRRFGGSVVESLPAMMETEMTEFVSTQVQGGVAYLTLTRPQALNALSLEMIRAITGALQSWENDPAVHAMVVAGAG
GKAFCAGGDIRWFYQAHQANDPLLDQFFVEEYALNHLIHRYAKPYIALMDGVVMGGGMGISQGARLRIVTERTKMAMPET
NIGLFPDVGGGWFLARTQGHIGEYLGLTGAVIGAADAIYAKLADAYLPTNAIAEMVASLQARQFTSGEAVLEQIASFTRQ
HADACVPSTSQLASNAALIDTLFAGASAQAILAAVSDAEGDWAAQTAATLRSRSPLMLCVTLEQIRRARTMSLEDELRME
LDMMHDVFRHGDGIEGIRALVIDKDHQPKWNPPRLDEVSGARVRAFFDSPWRKDDHPLATLGA
>Mature_383_residues
MLCRGRRFGGSVVESLPAMMETEMTEFVSTQVQGGVAYLTLTRPQALNALSLEMIRAITGALQSWENDPAVHAMVVAGAG
GKAFCAGGDIRWFYQAHQANDPLLDQFFVEEYALNHLIHRYAKPYIALMDGVVMGGGMGISQGARLRIVTERTKMAMPET
NIGLFPDVGGGWFLARTQGHIGEYLGLTGAVIGAADAIYAKLADAYLPTNAIAEMVASLQARQFTSGEAVLEQIASFTRQ
HADACVPSTSQLASNAALIDTLFAGASAQAILAAVSDAEGDWAAQTAATLRSRSPLMLCVTLEQIRRARTMSLEDELRME
LDMMHDVFRHGDGIEGIRALVIDKDHQPKWNPPRLDEVSGARVRAFFDSPWRKDDHPLATLGA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=362, Percent_Identity=35.6353591160221, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI37594469, Length=313, Percent_Identity=35.1437699680511, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI194097323, Length=182, Percent_Identity=35.7142857142857, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI68989263, Length=195, Percent_Identity=30.2564102564103, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787660, Length=160, Percent_Identity=33.75, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI221142681, Length=176, Percent_Identity=28.4090909090909, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787659, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=344, Percent_Identity=40.9883720930233, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI25144157, Length=343, Percent_Identity=41.1078717201166, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17554946, Length=219, Percent_Identity=26.9406392694064, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=353, Percent_Identity=28.6118980169972, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28571730, Length=362, Percent_Identity=35.9116022099448, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI28571729, Length=362, Percent_Identity=35.9116022099448, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI20129971, Length=196, Percent_Identity=31.1224489795918, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24653477, Length=196, Percent_Identity=31.1224489795918, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24653139, Length=221, Percent_Identity=26.6968325791855, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 41481; Mature: 41481

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCRGRRFGGSVVESLPAMMETEMTEFVSTQVQGGVAYLTLTRPQALNALSLEMIRAITG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHH
ALQSWENDPAVHAMVVAGAGGKAFCAGGDIRWFYQAHQANDPLLDQFFVEEYALNHLIHR
HHHCCCCCCCEEEEEEECCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
YAKPYIALMDGVVMGGGMGISQGARLRIVTERTKMAMPETNIGLFPDVGGGWFLARTQGH
HHCHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCCCCCEEEEECCCH
IGEYLGLTGAVIGAADAIYAKLADAYLPTNAIAEMVASLQARQFTSGEAVLEQIASFTRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
HADACVPSTSQLASNAALIDTLFAGASAQAILAAVSDAEGDWAAQTAATLRSRSPLMLCV
HHHHCCCCHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEE
TLEQIRRARTMSLEDELRMELDMMHDVFRHGDGIEGIRALVIDKDHQPKWNPPRLDEVSG
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
ARVRAFFDSPWRKDDHPLATLGA
CEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLCRGRRFGGSVVESLPAMMETEMTEFVSTQVQGGVAYLTLTRPQALNALSLEMIRAITG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHH
ALQSWENDPAVHAMVVAGAGGKAFCAGGDIRWFYQAHQANDPLLDQFFVEEYALNHLIHR
HHHCCCCCCCEEEEEEECCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
YAKPYIALMDGVVMGGGMGISQGARLRIVTERTKMAMPETNIGLFPDVGGGWFLARTQGH
HHCHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCCCCCEEEEECCCH
IGEYLGLTGAVIGAADAIYAKLADAYLPTNAIAEMVASLQARQFTSGEAVLEQIASFTRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
HADACVPSTSQLASNAALIDTLFAGASAQAILAAVSDAEGDWAAQTAATLRSRSPLMLCV
HHHHCCCCHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEE
TLEQIRRARTMSLEDELRMELDMMHDVFRHGDGIEGIRALVIDKDHQPKWNPPRLDEVSG
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
ARVRAFFDSPWRKDDHPLATLGA
CEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA