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The map label for this gene is phnW [H]

Identifier: 94310748

GI number: 94310748

Start: 1962310

End: 1963377

Strand: Direct

Name: phnW [H]

Synonym: Rmet_1810

Alternate gene names: 94310748

Gene position: 1962310-1963377 (Clockwise)

Preceding gene: 94310747

Following gene: 94310755

Centisome position: 49.96

GC content: 66.1

Gene sequence:

>1068_bases
ATGCTGCTGCTTAACCCGGGCCCCGTCACGCTTTCGGAACGCGTGCGCCGGAGCCTGCTGCAAACCGACCTGTGCCATCG
CGAAAGCGAGTTTTTCGACCTGCAGGACGAAGCGCGCGATCGGCTGCTCAACATCTACGCGCTCGACCCCGCGGCATGGA
CGGCGGTACTGATGACCGGCTCCGGCACGGCTGCGCTGGAAAGCATGATCGCGGCGATGGTGCCCGCCAACGGCAAGCTG
CTGATCGTGCAGAACGGCGTGTACGGCGAGCGCATCGCGCAGATCGCCGCGCAGTACCAGATCGCGCATGCGCTGGTGAA
GCACGATTGGATGGAAGCGCCCGACCTGGCCCGCATCGACGCGGCGCTGGCCGAAGATCCCGCCATCACCCACGTGGCCG
TGATCCATCACGAAACCACGACTGGTCGGCTGAATGACCTGTCGGCGATCGACCGTCTGTGCCAGGCACGTGGCGTGCGT
CTGCTGGTGGACACGGTGAGCAGCTTCGGCGCGGAAGCGATCGACTTCAGCGGCAATATCGACGCGGTGTGCTCCACGGC
GAACAAGTGCCTGCACGGCGTGCCGGGTGCGGCTTTTGTGATTGCGCGCCGCGCCGCGCTGACCCATGCGGCAACCCGTA
CGTACTACCTGGATCTCGTTCGCCTGGCAAAGCTGCAGGACCAGCGCAACACGCCGTTCACGCCGTCCGTCCATGCGTAC
TACGCGCTGGTGGAAGCGCTGCGCGAGCATCAGGAAGAAGGCGGCTGGAAAGGTCGTCACCAGCGCTATGCGGCGCTGGC
CGAACAGGCGCGCGCCGGTCTGGCCGCGCTGGGCATCGAGGCACTCTGGCCCGCCGAGCAGTCGTCGGTGGTGCTGCGCG
CCTACCGCCTGCCCAACGGCGTCACGTACGAGCAGCTTCACGACGGCCTAAAGGCCCGTGGATTCGTGATCTACGCTGGC
CAGGGCGGCCTGTCTTCGCAACTGTTCCGCATCTCGACGATGGGCGCGATCACGGCAGCCGATATCGACAGGCTGATCGA
GGGTTTCAAGGCGCTGGTGCAGCGCTGA

Upstream 100 bases:

>100_bases
ACGCCTGACGGGCTGCCGCGTCCGTCGGTGACGCCGGTGGAAGTCAAGACGCGCCTTGGCCGCCAGATCGGCGCCGACCA
GGGCCATGCCGGAGAGAAGC

Downstream 100 bases:

>100_bases
GCCCACGGTGGTTCTTCTCCCCTCTCCCCGCCGTGCGGGAGAGGGGGAAAACAACACGCAAAGTCGTTCGCTACAACTGC
GATTCCACCGGCAACATCCG

Product: 2-aminoethylphosphonate-pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MLLLNPGPVTLSERVRRSLLQTDLCHRESEFFDLQDEARDRLLNIYALDPAAWTAVLMTGSGTAALESMIAAMVPANGKL
LIVQNGVYGERIAQIAAQYQIAHALVKHDWMEAPDLARIDAALAEDPAITHVAVIHHETTTGRLNDLSAIDRLCQARGVR
LLVDTVSSFGAEAIDFSGNIDAVCSTANKCLHGVPGAAFVIARRAALTHAATRTYYLDLVRLAKLQDQRNTPFTPSVHAY
YALVEALREHQEEGGWKGRHQRYAALAEQARAGLAALGIEALWPAEQSSVVLRAYRLPNGVTYEQLHDGLKARGFVIYAG
QGGLSSQLFRISTMGAITAADIDRLIEGFKALVQR

Sequences:

>Translated_355_residues
MLLLNPGPVTLSERVRRSLLQTDLCHRESEFFDLQDEARDRLLNIYALDPAAWTAVLMTGSGTAALESMIAAMVPANGKL
LIVQNGVYGERIAQIAAQYQIAHALVKHDWMEAPDLARIDAALAEDPAITHVAVIHHETTTGRLNDLSAIDRLCQARGVR
LLVDTVSSFGAEAIDFSGNIDAVCSTANKCLHGVPGAAFVIARRAALTHAATRTYYLDLVRLAKLQDQRNTPFTPSVHAY
YALVEALREHQEEGGWKGRHQRYAALAEQARAGLAALGIEALWPAEQSSVVLRAYRLPNGVTYEQLHDGLKARGFVIYAG
QGGLSSQLFRISTMGAITAADIDRLIEGFKALVQR
>Mature_355_residues
MLLLNPGPVTLSERVRRSLLQTDLCHRESEFFDLQDEARDRLLNIYALDPAAWTAVLMTGSGTAALESMIAAMVPANGKL
LIVQNGVYGERIAQIAAQYQIAHALVKHDWMEAPDLARIDAALAEDPAITHVAVIHHETTTGRLNDLSAIDRLCQARGVR
LLVDTVSSFGAEAIDFSGNIDAVCSTANKCLHGVPGAAFVIARRAALTHAATRTYYLDLVRLAKLQDQRNTPFTPSVHAY
YALVEALREHQEEGGWKGRHQRYAALAEQARAGLAALGIEALWPAEQSSVVLRAYRLPNGVTYEQLHDGLKARGFVIYAG
QGGLSSQLFRISTMGAITAADIDRLIEGFKALVQR

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=379, Percent_Identity=26.6490765171504, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536281, Length=359, Percent_Identity=24.7910863509749, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17530823, Length=348, Percent_Identity=24.4252873563218, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 38702; Mature: 38702

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLNPGPVTLSERVRRSLLQTDLCHRESEFFDLQDEARDRLLNIYALDPAAWTAVLMTG
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEEEEEEECCHHEEEEEEEC
SGTAALESMIAAMVPANGKLLIVQNGVYGERIAQIAAQYQIAHALVKHDWMEAPDLARID
CCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AALAEDPAITHVAVIHHETTTGRLNDLSAIDRLCQARGVRLLVDTVSSFGAEAIDFSGNI
HHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCCEEECCCCH
DAVCSTANKCLHGVPGAAFVIARRAALTHAATRTYYLDLVRLAKLQDQRNTPFTPSVHAY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
YALVEALREHQEEGGWKGRHQRYAALAEQARAGLAALGIEALWPAEQSSVVLRAYRLPNG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHCHHHCCCCCCCCCEEEEEECCCC
VTYEQLHDGLKARGFVIYAGQGGLSSQLFRISTMGAITAADIDRLIEGFKALVQR
CCHHHHHCCHHHCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLLNPGPVTLSERVRRSLLQTDLCHRESEFFDLQDEARDRLLNIYALDPAAWTAVLMTG
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEEEEEEECCHHEEEEEEEC
SGTAALESMIAAMVPANGKLLIVQNGVYGERIAQIAAQYQIAHALVKHDWMEAPDLARID
CCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AALAEDPAITHVAVIHHETTTGRLNDLSAIDRLCQARGVRLLVDTVSSFGAEAIDFSGNI
HHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCCEEECCCCH
DAVCSTANKCLHGVPGAAFVIARRAALTHAATRTYYLDLVRLAKLQDQRNTPFTPSVHAY
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
YALVEALREHQEEGGWKGRHQRYAALAEQARAGLAALGIEALWPAEQSSVVLRAYRLPNG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHCHHHCCCCCCCCCEEEEEECCCC
VTYEQLHDGLKARGFVIYAGQGGLSSQLFRISTMGAITAADIDRLIEGFKALVQR
CCHHHHHCCHHHCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA