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The map label for this gene is poxR [H]

Identifier: 94310726

GI number: 94310726

Start: 1938998

End: 1940626

Strand: Direct

Name: poxR [H]

Synonym: Rmet_1788

Alternate gene names: 94310726

Gene position: 1938998-1940626 (Clockwise)

Preceding gene: 94310718

Following gene: 94310727

Centisome position: 49.36

GC content: 64.83

Gene sequence:

>1629_bases
ATGACAACACCCCCCGCGCAGCCGCCGTTCGAGCTGGCTTCGCTACTGACCATCGACGCCAAGGCCGCGCAGATTCGCCT
TGGCCAGTCGCGCATGGTGCTGATGCACACCGAGGCGCTGAGCTACCTGCGCAAGGAAATCCTCGATACGCTTGGCGTGG
AGCGCGGCAAGGGGCTGCTGATCCGCATGGGCTACGCGCAAGGCATGCGCGATGCCGAGATGGTCAAGCGCGAGCGCAGT
GAAGAACTGGCCAGTTCGCCCAACGATGCCTTCCTTTGGGGGCCGCAGTTGCACATGCTCGAAGGCGTCACGCGCGTGGA
CCCGGTTCGCCTGGAGATCGACCGCGACACCGGCCACTTCTATGGCGAGTTTCTCTGGCAGGACTCATGGGAGGGCGAAG
CGCCCGTGATGGAGTCCCTGCCCCGCGAGGAGTCTGGCTGCTGGGTGCAGCTTGGCTACGCATCGGGCTACAGCAGCACG
TTCATGGACCGGCTGGTCATCTACAAGGAAACCGAATGCGAGCGGCGCGGCGACAGTCTCTGCCGCATCGTCGGCAAGCC
GGCCGAGACGTGGAACGACCCCGACTACCTGAAGTACTTCGAACCCGACTCCGTCATCAGCGACCTGCTCACCCTGCAGC
AGGAAGTCAGCACACTGCGCGAAACACTGTGTGGCGCGAACCAGGGCAACCTGATCGGCCAGTCGCCGGCGTTCCGTGAA
GCCTTCAACCTGCTTTCCGCCGCGGCAGACAGCCATATCACCGTGCTGCTGACGGGCGAGACCGGTGCCGGCAAGGAGAT
GTTCGCGCGCTGGCTGCACGATCACGGCCCGCGCGGCGAGCAGCCGTTCGTCGCGGTCAACTGCGCGGCGATCCCGCACG
AGTTGATCGAATCCGAGCTGTTCGGCGTGGAAAAAGGCGCCTACACGGGCGCCCAGCAGTCGCGCCCCGGCCGCTTTGAA
CGCGCGCATGGCGGCACCCTGTTCCTCGACGAAATCGGCGACCTGCCGCCGGCCGCGCAGGTCAAGCTGCTGCGCGTGCT
GCAGAACAACGAAGTGGAACGGCTCGGTGGCGTGGAGGCGCGCAAGGTCAACGTCCGCCTGATCGCCGCCACCAACGTCA
ATCTGGCGCAGGCGATCAAGCACGGCCAGTTTCGTGCTGACCTGTTCTACCGGATCAGCACCTATCCGATCTCGATCCCC
GCCCTGCGCGAGCGCAAGGAAGACATCCCCGAGCTCGCCCAGTCATTCATCCAGCGCTTCAACGCGCTGTATCAGAAGCA
GGTGCGCGGCTTGAGCACGCGGGCGCGCGATGCGCTGGTGCAATACCCGTGGCCCGGCAATATCCGCGAACTCGAAAACA
TGATCGAGCGTGGCGTCTTGCTGGCGCCTGCCACCGGGATGATCGACGTCGCTCATCTGTTTGCCAGCCAGCAGGCTGCC
GGTAGCGAGGAGCCCAGCCAGGATGCCGACGCGCTGATCGAAAAACTGCTCAACCAGCAGGTGTCCCTGCCGCAAATCGA
AGCCAAGCTGATGCAACTGGCGATGACGACGACGCGTGGCAACCTGTCGTCGGCGGCGCGGATGCTGGGGATCACGCGGC
CGCAGCTGGCGTATCGGTTGAAGAAGTAG

Upstream 100 bases:

>100_bases
GCTCCTGATGCGGGATTTCCGGGCTCCGGCAACGCCGGATGCCGTGCTAGGCTACGCAAAAACGAGGCTCGAAAGCCCGC
CGGAATCTGGAGTGACAAGG

Downstream 100 bases:

>100_bases
GGTTGGGACAGATGGCCCAGCCCGCTCGACACCCGAGTTATTAAGTATTTACCCTAGGTTTTCATATAACCAGAAAAGGG
TAAGGTGTCGTCCCATGCAG

Product: phenol hydroxylase genes transcriptional regulator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MTTPPAQPPFELASLLTIDAKAAQIRLGQSRMVLMHTEALSYLRKEILDTLGVERGKGLLIRMGYAQGMRDAEMVKRERS
EELASSPNDAFLWGPQLHMLEGVTRVDPVRLEIDRDTGHFYGEFLWQDSWEGEAPVMESLPREESGCWVQLGYASGYSST
FMDRLVIYKETECERRGDSLCRIVGKPAETWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
AFNLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRGEQPFVAVNCAAIPHELIESELFGVEKGAYTGAQQSRPGRFE
RAHGGTLFLDEIGDLPPAAQVKLLRVLQNNEVERLGGVEARKVNVRLIAATNVNLAQAIKHGQFRADLFYRISTYPISIP
ALRERKEDIPELAQSFIQRFNALYQKQVRGLSTRARDALVQYPWPGNIRELENMIERGVLLAPATGMIDVAHLFASQQAA
GSEEPSQDADALIEKLLNQQVSLPQIEAKLMQLAMTTTRGNLSSAARMLGITRPQLAYRLKK

Sequences:

>Translated_542_residues
MTTPPAQPPFELASLLTIDAKAAQIRLGQSRMVLMHTEALSYLRKEILDTLGVERGKGLLIRMGYAQGMRDAEMVKRERS
EELASSPNDAFLWGPQLHMLEGVTRVDPVRLEIDRDTGHFYGEFLWQDSWEGEAPVMESLPREESGCWVQLGYASGYSST
FMDRLVIYKETECERRGDSLCRIVGKPAETWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
AFNLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRGEQPFVAVNCAAIPHELIESELFGVEKGAYTGAQQSRPGRFE
RAHGGTLFLDEIGDLPPAAQVKLLRVLQNNEVERLGGVEARKVNVRLIAATNVNLAQAIKHGQFRADLFYRISTYPISIP
ALRERKEDIPELAQSFIQRFNALYQKQVRGLSTRARDALVQYPWPGNIRELENMIERGVLLAPATGMIDVAHLFASQQAA
GSEEPSQDADALIEKLLNQQVSLPQIEAKLMQLAMTTTRGNLSSAARMLGITRPQLAYRLKK
>Mature_541_residues
TTPPAQPPFELASLLTIDAKAAQIRLGQSRMVLMHTEALSYLRKEILDTLGVERGKGLLIRMGYAQGMRDAEMVKRERSE
ELASSPNDAFLWGPQLHMLEGVTRVDPVRLEIDRDTGHFYGEFLWQDSWEGEAPVMESLPREESGCWVQLGYASGYSSTF
MDRLVIYKETECERRGDSLCRIVGKPAETWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFREA
FNLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRGEQPFVAVNCAAIPHELIESELFGVEKGAYTGAQQSRPGRFER
AHGGTLFLDEIGDLPPAAQVKLLRVLQNNEVERLGGVEARKVNVRLIAATNVNLAQAIKHGQFRADLFYRISTYPISIPA
LRERKEDIPELAQSFIQRFNALYQKQVRGLSTRARDALVQYPWPGNIRELENMIERGVLLAPATGMIDVAHLFASQQAAG
SEEPSQDADALIEKLLNQQVSLPQIEAKLMQLAMTTTRGNLSSAARMLGITRPQLAYRLKK

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=317, Percent_Identity=44.794952681388, Blast_Score=268, Evalue=1e-72,
Organism=Escherichia coli, GI87082117, Length=253, Percent_Identity=52.1739130434783, Blast_Score=255, Evalue=6e-69,
Organism=Escherichia coli, GI1788550, Length=340, Percent_Identity=40.5882352941176, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1790299, Length=368, Percent_Identity=39.945652173913, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1788905, Length=318, Percent_Identity=39.937106918239, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1789087, Length=262, Percent_Identity=44.6564885496183, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87081872, Length=327, Percent_Identity=40.9785932721713, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=40.625, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1786524, Length=326, Percent_Identity=41.1042944785276, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=38.9408099688474, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787583, Length=229, Percent_Identity=37.117903930131, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87081858, Length=311, Percent_Identity=30.2250803858521, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789828, Length=226, Percent_Identity=37.1681415929204, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 60435; Mature: 60304

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPAQPPFELASLLTIDAKAAQIRLGQSRMVLMHTEALSYLRKEILDTLGVERGKGLL
CCCCCCCCHHHHHHHHHCCCHHHHEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEE
IRMGYAQGMRDAEMVKRERSEELASSPNDAFLWGPQLHMLEGVTRVDPVRLEIDRDTGHF
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCCEEEEEECCCCCH
YGEFLWQDSWEGEAPVMESLPREESGCWVQLGYASGYSSTFMDRLVIYKETECERRGDSL
HHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHEECCHHHHHHHHH
CRIVGKPAETWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
HHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AFNLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRGEQPFVAVNCAAIPHELIESEL
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCHHHHHHHH
FGVEKGAYTGAQQSRPGRFERAHGGTLFLDEIGDLPPAAQVKLLRVLQNNEVERLGGVEA
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCE
RKVNVRLIAATNVNLAQAIKHGQFRADLFYRISTYPISIPALRERKEDIPELAQSFIQRF
EEEEEEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
NALYQKQVRGLSTRARDALVQYPWPGNIRELENMIERGVLLAPATGMIDVAHLFASQQAA
HHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHC
GSEEPSQDADALIEKLLNQQVSLPQIEAKLMQLAMTTTRGNLSSAARMLGITRPQLAYRL
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHC
KK
CC
>Mature Secondary Structure 
TTPPAQPPFELASLLTIDAKAAQIRLGQSRMVLMHTEALSYLRKEILDTLGVERGKGLL
CCCCCCCHHHHHHHHHCCCHHHHEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEE
IRMGYAQGMRDAEMVKRERSEELASSPNDAFLWGPQLHMLEGVTRVDPVRLEIDRDTGHF
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCCEEEEEECCCCCH
YGEFLWQDSWEGEAPVMESLPREESGCWVQLGYASGYSSTFMDRLVIYKETECERRGDSL
HHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHEECCHHHHHHHHH
CRIVGKPAETWNDPDYLKYFEPDSVISDLLTLQQEVSTLRETLCGANQGNLIGQSPAFRE
HHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AFNLLSAAADSHITVLLTGETGAGKEMFARWLHDHGPRGEQPFVAVNCAAIPHELIESEL
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCHHHHHHHH
FGVEKGAYTGAQQSRPGRFERAHGGTLFLDEIGDLPPAAQVKLLRVLQNNEVERLGGVEA
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCE
RKVNVRLIAATNVNLAQAIKHGQFRADLFYRISTYPISIPALRERKEDIPELAQSFIQRF
EEEEEEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
NALYQKQVRGLSTRARDALVQYPWPGNIRELENMIERGVLLAPATGMIDVAHLFASQQAA
HHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHC
GSEEPSQDADALIEKLLNQQVSLPQIEAKLMQLAMTTTRGNLSSAARMLGITRPQLAYRL
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHC
KK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]