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The map label for this gene is yheS [H]

Identifier: 94310697

GI number: 94310697

Start: 1909327

End: 1910991

Strand: Direct

Name: yheS [H]

Synonym: Rmet_1759

Alternate gene names: 94310697

Gene position: 1909327-1910991 (Clockwise)

Preceding gene: 94310696

Following gene: 94310699

Centisome position: 48.61

GC content: 63.6

Gene sequence:

>1665_bases
ATGATTTCCGTCCGTAATGTCACGCTGCGTCGTGGCGTCAATGTCGTACTTGACCGCGCATCCGTCACCTTCAACCCCGG
CGAAAAGATCGGTCTTGTCGGCCGCAATGGCGCCGGCAAGTCATCCTTCTTCGGCCTTCTCAATGGCACGCTGCACGAAG
ACAGCGGCGAGTTCTCGATTCCCGCTGCATGGAAGATGGGCCAGGTCGCGCAGGAGATGCCAGAGACCGAGCAAAGCGCG
ACCGACTTCGTAGTCGAGGGTGACACCGCGCTGTTGGCCGCGCAGACCGAAGTCGCCGCCGCCGAGGCCTGCGACGACGG
CATGCGCATGGCGCACGCCTACATGGCCCTGCACGACGCCGGTGCGCACGATGCCCCTGCCCGTGCCCAAGCGCTGATCC
TGGGCCTTGGCTTCAGTGCTGCGCAGCTTAGTCAGCCGGTCAACAGTTTCTCCGGCGGCTGGCGCATGCGACTGCAACTG
GCGCGCGCGCTCATGTGCCCGTCCGACCTGCTGCTGCTCGACGAGCCAACGAATCACCTTGACCTCGACGCGCTGGTCTG
GCTGGAAGCCTGGCTCAAGCGCTATCAAGGAACCCTCGTAGTGATCAGCCACGACCGCGAGTTTCTCGATGCGGTGACGC
AGGTGACGGTGCACGTCGACAACGCCCAGCTCGTGCGCTATGGCGGCAACTACAGCAAATTTGAAGACATGCGAGCTGAA
CAGCTCGTATTGCAGCAGGCCGCGATGGCCAAGCAGGCGGACAAGATCGCCCACCTGCAGAAATTCATCGACCGCTTCAA
GGCCAAGGCCTCGAAGGAGAAGCAGGCGCAGAGCCGCGTCAAGGCGCTCGAACGCATGGAGAAGATCGCACCGGTGCTTG
CCGACGCAGAGTTCAACTTCGAGTTCAAGGAGCCGCTCAACGTCCCGAACCCGCTGCTGTCGATGCTGGACACGAGCTTC
GGCTACCCGGCGCCAGCCGGCGCACTGCCGGGCACGCCGCCCACGGTCATCGTACGAGGCATCAACCGTTCCGTGCTGGC
CGGGCAGCGCATCGGCATTCTCGGTGCCAACGGCCAGGGCAAGTCCACGCTGGTGAAGACGGTGGCGCATGCGCTGGCGC
CGATCGCCGGCGAAATCAGCGAAGGCAAAGGCCTGAATATCGGCTACTTCGCACAGCAGGAGCTCGACGTGCTGCGCCCG
CTCGACACGCCGATGGAACACATGATCCGCCTTGCAAAGGGGACGCCGGCTCACATGCGCGCCCCCGGCCAGAGTGGAAC
CGAACAATCCCTTCGCACCTTCCTTGGCACCTTCAACTTCAGTGGCGACATGGTCCATCAGGCGGTCAGCACGATGAGCG
GCGGCGAAAAGGCGCGGCTCGTGTTGTGCATGATCGTGTGGCAGCGCCCGAACCTGCTGCTGCTCGACGAGCCTACCAAC
CACCTCGACTTGGCCACACGCGAAGCGCTCGGCATGGCGCTCAACGAATTCGAAGGCACTGTGATGTTGGTCAGTCACGA
CCGCGCTCTGCTGCGCGCCGTATGTGACGAGTTCTGGCTGGTCACCAAGGGCGGCGTCGAGCCCTTCGACGGCGATCTGG
ACGATTACCAGCAGTTTTTGCGCGACGAAGCCCGTCGCATACGCGAACAGGCTGCCGCAGCGTAG

Upstream 100 bases:

>100_bases
TTCGCGTGCCCCGTCGCCGGAACGCCCGGCGCGGCCAGAAAAGCGACCGCCCTGCACGCCCGGTCGGCTATCATGCCTAT
CCTCTCCGAAGTAGCTCCCT

Downstream 100 bases:

>100_bases
ACGCACATCGGCTGAAGTGGGCCAATGGGAACGCGTGCCCTTCACAGGATTCAGCGCAAAGGGAACCATTGAGGGCCTCG
AGACTGATTCGAACTCGGAC

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MISVRNVTLRRGVNVVLDRASVTFNPGEKIGLVGRNGAGKSSFFGLLNGTLHEDSGEFSIPAAWKMGQVAQEMPETEQSA
TDFVVEGDTALLAAQTEVAAAEACDDGMRMAHAYMALHDAGAHDAPARAQALILGLGFSAAQLSQPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLKRYQGTLVVISHDREFLDAVTQVTVHVDNAQLVRYGGNYSKFEDMRAE
QLVLQQAAMAKQADKIAHLQKFIDRFKAKASKEKQAQSRVKALERMEKIAPVLADAEFNFEFKEPLNVPNPLLSMLDTSF
GYPAPAGALPGTPPTVIVRGINRSVLAGQRIGILGANGQGKSTLVKTVAHALAPIAGEISEGKGLNIGYFAQQELDVLRP
LDTPMEHMIRLAKGTPAHMRAPGQSGTEQSLRTFLGTFNFSGDMVHQAVSTMSGGEKARLVLCMIVWQRPNLLLLDEPTN
HLDLATREALGMALNEFEGTVMLVSHDRALLRAVCDEFWLVTKGGVEPFDGDLDDYQQFLRDEARRIREQAAAA

Sequences:

>Translated_554_residues
MISVRNVTLRRGVNVVLDRASVTFNPGEKIGLVGRNGAGKSSFFGLLNGTLHEDSGEFSIPAAWKMGQVAQEMPETEQSA
TDFVVEGDTALLAAQTEVAAAEACDDGMRMAHAYMALHDAGAHDAPARAQALILGLGFSAAQLSQPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLKRYQGTLVVISHDREFLDAVTQVTVHVDNAQLVRYGGNYSKFEDMRAE
QLVLQQAAMAKQADKIAHLQKFIDRFKAKASKEKQAQSRVKALERMEKIAPVLADAEFNFEFKEPLNVPNPLLSMLDTSF
GYPAPAGALPGTPPTVIVRGINRSVLAGQRIGILGANGQGKSTLVKTVAHALAPIAGEISEGKGLNIGYFAQQELDVLRP
LDTPMEHMIRLAKGTPAHMRAPGQSGTEQSLRTFLGTFNFSGDMVHQAVSTMSGGEKARLVLCMIVWQRPNLLLLDEPTN
HLDLATREALGMALNEFEGTVMLVSHDRALLRAVCDEFWLVTKGGVEPFDGDLDDYQQFLRDEARRIREQAAAA
>Mature_554_residues
MISVRNVTLRRGVNVVLDRASVTFNPGEKIGLVGRNGAGKSSFFGLLNGTLHEDSGEFSIPAAWKMGQVAQEMPETEQSA
TDFVVEGDTALLAAQTEVAAAEACDDGMRMAHAYMALHDAGAHDAPARAQALILGLGFSAAQLSQPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLKRYQGTLVVISHDREFLDAVTQVTVHVDNAQLVRYGGNYSKFEDMRAE
QLVLQQAAMAKQADKIAHLQKFIDRFKAKASKEKQAQSRVKALERMEKIAPVLADAEFNFEFKEPLNVPNPLLSMLDTSF
GYPAPAGALPGTPPTVIVRGINRSVLAGQRIGILGANGQGKSTLVKTVAHALAPIAGEISEGKGLNIGYFAQQELDVLRP
LDTPMEHMIRLAKGTPAHMRAPGQSGTEQSLRTFLGTFNFSGDMVHQAVSTMSGGEKARLVLCMIVWQRPNLLLLDEPTN
HLDLATREALGMALNEFEGTVMLVSHDRALLRAVCDEFWLVTKGGVEPFDGDLDDYQQFLRDEARRIREQAAAA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=554, Percent_Identity=35.9205776173285, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI27881506, Length=548, Percent_Identity=33.3941605839416, Blast_Score=298, Evalue=8e-81,
Organism=Homo sapiens, GI10947137, Length=548, Percent_Identity=33.3941605839416, Blast_Score=298, Evalue=9e-81,
Organism=Homo sapiens, GI10947135, Length=566, Percent_Identity=32.5088339222615, Blast_Score=245, Evalue=9e-65,
Organism=Homo sapiens, GI69354671, Length=566, Percent_Identity=32.5088339222615, Blast_Score=245, Evalue=1e-64,
Organism=Homo sapiens, GI255708477, Length=210, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789751, Length=542, Percent_Identity=51.1070110701107, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1787041, Length=544, Percent_Identity=32.5367647058824, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1787182, Length=522, Percent_Identity=31.0344827586207, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI2367384, Length=547, Percent_Identity=31.4442413162706, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87081782, Length=556, Percent_Identity=23.021582733813, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788165, Length=180, Percent_Identity=32.2222222222222, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787500, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789891, Length=216, Percent_Identity=28.2407407407407, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788506, Length=250, Percent_Identity=22.4, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787758, Length=239, Percent_Identity=27.6150627615063, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87081709, Length=211, Percent_Identity=25.5924170616114, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI145693107, Length=540, Percent_Identity=21.4814814814815, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786398, Length=206, Percent_Identity=25.2427184466019, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=549, Percent_Identity=36.976320582878, Blast_Score=339, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17559834, Length=574, Percent_Identity=32.404181184669, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17555318, Length=554, Percent_Identity=34.115523465704, Blast_Score=288, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6321121, Length=552, Percent_Identity=33.3333333333333, Blast_Score=314, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6320874, Length=545, Percent_Identity=32.2935779816514, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6325030, Length=398, Percent_Identity=27.3869346733668, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=412, Percent_Identity=26.2135922330097, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323278, Length=412, Percent_Identity=25, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24666836, Length=554, Percent_Identity=38.2671480144404, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=563, Percent_Identity=34.1030195381883, Blast_Score=309, Evalue=4e-84,
Organism=Drosophila melanogaster, GI18859989, Length=563, Percent_Identity=34.1030195381883, Blast_Score=309, Evalue=4e-84,
Organism=Drosophila melanogaster, GI24641342, Length=558, Percent_Identity=31.0035842293907, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI17136662, Length=297, Percent_Identity=26.2626262626263, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007184, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221500365, Length=192, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60392; Mature: 60392

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVRNVTLRRGVNVVLDRASVTFNPGEKIGLVGRNGAGKSSFFGLLNGTLHEDSGEFSI
CCCCCCCHHHCCCEEEEECCEEEECCCCEEEEEECCCCCCHHHHHHHCCEEECCCCCCCC
PAAWKMGQVAQEMPETEQSATDFVVEGDTALLAAQTEVAAAEACDDGMRMAHAYMALHDA
CCHHHHHHHHHHCCCCHHCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
GAHDAPARAQALILGLGFSAAQLSQPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCCCCHHEEEEEECCCCHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLKRYQGTLVVISHDREFLDAVTQVTVHVDNAQLVRYGGNYSKFEDMRAE
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHEEEEECCCEEEEECCCHHHHHHHHHH
QLVLQQAAMAKQADKIAHLQKFIDRFKAKASKEKQAQSRVKALERMEKIAPVLADAEFNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
EFKEPLNVPNPLLSMLDTSFGYPAPAGALPGTPPTVIVRGINRSVLAGQRIGILGANGQG
EECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCEEEEEECCCCC
KSTLVKTVAHALAPIAGEISEGKGLNIGYFAQQELDVLRPLDTPMEHMIRLAKGTPAHMR
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHCCCCCCHHHHHHHHCCCCHHCC
APGQSGTEQSLRTFLGTFNFSGDMVHQAVSTMSGGEKARLVLCMIVWQRPNLLLLDEPTN
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHEEEEEEEEECCCCEEEEECCCC
HLDLATREALGMALNEFEGTVMLVSHDRALLRAVCDEFWLVTKGGVEPFDGDLDDYQQFL
CHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHH
RDEARRIREQAAAA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MISVRNVTLRRGVNVVLDRASVTFNPGEKIGLVGRNGAGKSSFFGLLNGTLHEDSGEFSI
CCCCCCCHHHCCCEEEEECCEEEECCCCEEEEEECCCCCCHHHHHHHCCEEECCCCCCCC
PAAWKMGQVAQEMPETEQSATDFVVEGDTALLAAQTEVAAAEACDDGMRMAHAYMALHDA
CCHHHHHHHHHHCCCCHHCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
GAHDAPARAQALILGLGFSAAQLSQPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCCCCHHEEEEEECCCCHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLKRYQGTLVVISHDREFLDAVTQVTVHVDNAQLVRYGGNYSKFEDMRAE
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHEEEEECCCEEEEECCCHHHHHHHHHH
QLVLQQAAMAKQADKIAHLQKFIDRFKAKASKEKQAQSRVKALERMEKIAPVLADAEFNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
EFKEPLNVPNPLLSMLDTSFGYPAPAGALPGTPPTVIVRGINRSVLAGQRIGILGANGQG
EECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCEEEEEECCCCC
KSTLVKTVAHALAPIAGEISEGKGLNIGYFAQQELDVLRPLDTPMEHMIRLAKGTPAHMR
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHCCCCCCHHHHHHHHCCCCHHCC
APGQSGTEQSLRTFLGTFNFSGDMVHQAVSTMSGGEKARLVLCMIVWQRPNLLLLDEPTN
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHEEEEEEEEECCCCEEEEECCCC
HLDLATREALGMALNEFEGTVMLVSHDRALLRAVCDEFWLVTKGGVEPFDGDLDDYQQFL
CHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHH
RDEARRIREQAAAA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]