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The map label for this gene is marR [H]

Identifier: 94310543

GI number: 94310543

Start: 1727755

End: 1728192

Strand: Reverse

Name: marR [H]

Synonym: Rmet_1601

Alternate gene names: 94310543

Gene position: 1728192-1727755 (Counterclockwise)

Preceding gene: 335055535

Following gene: 94310534

Centisome position: 44.0

GC content: 58.45

Gene sequence:

>438_bases
GTGAAACACTACACACCCGAGAACTTCCATCTCACCCAGAGCATTGGTTTCCACCTGAACAAGGCACGCAACAGCCTGCT
TCTGGAAATGGATTCCGCATTACGTCCCCTGGATATCAACGGGCAACAGATGGGTATCCTGCTGGCGCTGACCCGCGGCA
TGGCGGGCACGCCGTTTGAGATCAGCAAGCTGCTCGGCATCGACAGCGGCCTGATGACGCGCATGCTCGACCGGCTCGAG
GAAAAAGGCCTGCTGGAACGCAGCCGCAGCATCGACGACCGTCGCGTGGTGAATCTGACCCTGACCTCCAAGGGCAGACT
GGTTTCGGCAGAGATCCCGTCGATCGCACCGGAAGTGCTGAATGAGCGACTGAAGGAATTCACGCCCGAAGAGTTCGACG
AATTCCGGCGCCTGCTGCAGAAGTTTGTTATGGGCTGA

Upstream 100 bases:

>100_bases
ACAACAAAACTAAATTCCCATTCTGTCGCGAATTCGCCAGACTTCTTTTCGGCAAGTGTCTGCATCACAAGTCTCTCGAT
CATCGAAAAAGGACACGATA

Downstream 100 bases:

>100_bases
CCACTCCTGGCGAGTTGCGCGCACAACCGGCCAGGTCGTGCGCCGGCTGCGCCTCGCGTCAGCGCGTGACGGACGCAAGC
CGTCGCGCTGACCCGCCCCC

Product: regulatory protein, MarR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKHYTPENFHLTQSIGFHLNKARNSLLLEMDSALRPLDINGQQMGILLALTRGMAGTPFEISKLLGIDSGLMTRMLDRLE
EKGLLERSRSIDDRRVVNLTLTSKGRLVSAEIPSIAPEVLNERLKEFTPEEFDEFRRLLQKFVMG

Sequences:

>Translated_145_residues
MKHYTPENFHLTQSIGFHLNKARNSLLLEMDSALRPLDINGQQMGILLALTRGMAGTPFEISKLLGIDSGLMTRMLDRLE
EKGLLERSRSIDDRRVVNLTLTSKGRLVSAEIPSIAPEVLNERLKEFTPEEFDEFRRLLQKFVMG
>Mature_145_residues
MKHYTPENFHLTQSIGFHLNKARNSLLLEMDSALRPLDINGQQMGILLALTRGMAGTPFEISKLLGIDSGLMTRMLDRLE
EKGLLERSRSIDDRRVVNLTLTSKGRLVSAEIPSIAPEVLNERLKEFTPEEFDEFRRLLQKFVMG

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=126, Percent_Identity=34.1269841269841, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16527; Mature: 16527

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHYTPENFHLTQSIGFHLNKARNSLLLEMDSALRPLDINGQQMGILLALTRGMAGTPFE
CCCCCCCCEEEHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCHHHHHEEECCCCCCCCHH
ISKLLGIDSGLMTRMLDRLEEKGLLERSRSIDDRRVVNLTLTSKGRLVSAEIPSIAPEVL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCHHHH
NERLKEFTPEEFDEFRRLLQKFVMG
HHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHYTPENFHLTQSIGFHLNKARNSLLLEMDSALRPLDINGQQMGILLALTRGMAGTPFE
CCCCCCCCEEEHHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCHHHHHEEECCCCCCCCHH
ISKLLGIDSGLMTRMLDRLEEKGLLERSRSIDDRRVVNLTLTSKGRLVSAEIPSIAPEVL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCCCHHHH
NERLKEFTPEEFDEFRRLLQKFVMG
HHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]