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The map label for this gene is hoxN [H]

Identifier: 94310475

GI number: 94310475

Start: 1653974

End: 1654810

Strand: Direct

Name: hoxN [H]

Synonym: Rmet_1533

Alternate gene names: 94310475

Gene position: 1653974-1654810 (Clockwise)

Preceding gene: 94310474

Following gene: 335055532

Centisome position: 42.11

GC content: 70.01

Gene sequence:

>837_bases
ATGGAAGCACTGCCGAACGATTGGGTGGCCCTGGCCGCGCTGGTCTTCATGCTGGGCGTCAAGCACGGCTTCGATGCCGA
TCATCTCGCCACCATCGATGGCCTGACCCGTTTCAACCTGCGCCATGGCGCCCCCGTCGCCCGTGCCTGCGGCATCCTGT
TCTCGCTGGGGCACGGCACGGTGGTCATCGCCATCGCCCTGGCCGTCAGCACCCTGGCCCGCCGCTGGCAGGTGCCCGGC
TGGCTGGAGGCCAGCGGTGCCTGGATTTCCATCGGCTTCCTCGTCGCGCTCGGCGTCATCAACCTGCGCGCCGTGCTCAC
CACGCGGCACGACGAGGTGGTGCAGCCCGTGGGTCTGAAGGGCCGCTGGCTCGGTCGGCTGCAGCATGCCTCCCATCCCC
TGGCCGTCGCCGCCGTCGGCGCGCTGTTCGCCCTGTCCTTCGACACCGTCAGCCAGGCCGCCCTGTTCGCCGCCGCCGGC
GCGCAGTATGGCGGATGGGGCCACGCCCTGGCGCTCGGGCTGCTGTTCACCCTCGGCATGCTGGTGATGGATGGCATCAA
CGGGCTGTGGATCTCCCGCCTCATCCGCCGCACCGACCAGATGGCCCTCGTCGCCTCCCGCGTCATGAGCCTGGCGGTGT
CAGGCACCAGCCTGCTGGTGGCGGCCTTCGGCGTCATGAGGCAACTGCTGCCCGCCGTGGACGCCTGGAGCGACGGCAAG
GAGCTGGCCTTCGGGCTGTCCGTGGTGTGCGTCATCGCTGGTAGCTTTTTTCTTGCGCTGCGCCTGACCCGGGTGCCGGC
GGTGGCAGCGGCGCGGCCCATGCGGTTCGTCGAATAG

Upstream 100 bases:

>100_bases
GGCGAAGTCATCACCCATGTGAAGGCGCTGGAGGTCTAATTTGATACAGTCAAATTAAGATGAAGTAGAATTTCTTCATA
ACCTAGTCCAGGGGAGCGGA

Downstream 100 bases:

>100_bases
CCGGGCCGCATCCGGCCACGCGCCGCATTCGTCTACCCGGCTGGCAACGTAGCGTTTAAGCTGCGCAGATTTTTAACCGG
ACACTACTGAGATCCGATCA

Product: High-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MEALPNDWVALAALVFMLGVKHGFDADHLATIDGLTRFNLRHGAPVARACGILFSLGHGTVVIAIALAVSTLARRWQVPG
WLEASGAWISIGFLVALGVINLRAVLTTRHDEVVQPVGLKGRWLGRLQHASHPLAVAAVGALFALSFDTVSQAALFAAAG
AQYGGWGHALALGLLFTLGMLVMDGINGLWISRLIRRTDQMALVASRVMSLAVSGTSLLVAAFGVMRQLLPAVDAWSDGK
ELAFGLSVVCVIAGSFFLALRLTRVPAVAAARPMRFVE

Sequences:

>Translated_278_residues
MEALPNDWVALAALVFMLGVKHGFDADHLATIDGLTRFNLRHGAPVARACGILFSLGHGTVVIAIALAVSTLARRWQVPG
WLEASGAWISIGFLVALGVINLRAVLTTRHDEVVQPVGLKGRWLGRLQHASHPLAVAAVGALFALSFDTVSQAALFAAAG
AQYGGWGHALALGLLFTLGMLVMDGINGLWISRLIRRTDQMALVASRVMSLAVSGTSLLVAAFGVMRQLLPAVDAWSDGK
ELAFGLSVVCVIAGSFFLALRLTRVPAVAAARPMRFVE
>Mature_278_residues
MEALPNDWVALAALVFMLGVKHGFDADHLATIDGLTRFNLRHGAPVARACGILFSLGHGTVVIAIALAVSTLARRWQVPG
WLEASGAWISIGFLVALGVINLRAVLTTRHDEVVQPVGLKGRWLGRLQHASHPLAVAAVGALFALSFDTVSQAALFAAAG
AQYGGWGHALALGLLFTLGMLVMDGINGLWISRLIRRTDQMALVASRVMSLAVSGTSLLVAAFGVMRQLLPAVDAWSDGK
ELAFGLSVVCVIAGSFFLALRLTRVPAVAAARPMRFVE

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 29393; Mature: 29393

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALPNDWVALAALVFMLGVKHGFDADHLATIDGLTRFNLRHGAPVARACGILFSLGHGT
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
VVIAIALAVSTLARRWQVPGWLEASGAWISIGFLVALGVINLRAVLTTRHDEVVQPVGLK
HHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
GRWLGRLQHASHPLAVAAVGALFALSFDTVSQAALFAAAGAQYGGWGHALALGLLFTLGM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LVMDGINGLWISRLIRRTDQMALVASRVMSLAVSGTSLLVAAFGVMRQLLPAVDAWSDGK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCH
ELAFGLSVVCVIAGSFFLALRLTRVPAVAAARPMRFVE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MEALPNDWVALAALVFMLGVKHGFDADHLATIDGLTRFNLRHGAPVARACGILFSLGHGT
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCH
VVIAIALAVSTLARRWQVPGWLEASGAWISIGFLVALGVINLRAVLTTRHDEVVQPVGLK
HHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
GRWLGRLQHASHPLAVAAVGALFALSFDTVSQAALFAAAGAQYGGWGHALALGLLFTLGM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LVMDGINGLWISRLIRRTDQMALVASRVMSLAVSGTSLLVAAFGVMRQLLPAVDAWSDGK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCH
ELAFGLSVVCVIAGSFFLALRLTRVPAVAAARPMRFVE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]