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The map label for this gene is cbbJ1 [H]

Identifier: 94310462

GI number: 94310462

Start: 1642414

End: 1643232

Strand: Direct

Name: cbbJ1 [H]

Synonym: Rmet_1520

Alternate gene names: 94310462

Gene position: 1642414-1643232 (Clockwise)

Preceding gene: 94310461

Following gene: 94310463

Centisome position: 41.81

GC content: 69.6

Gene sequence:

>819_bases
ATGGACCCGACCCCCCTCCCGCCGCACCCAGTTCGCGGCCAACGCCGACGACTGCTGGTGGCCGGCAACTGGAAGATGAA
CGGCAGTCTGGCCGGCGTACAGGCGCTGGCGGCGGCGATCGCCGACGGTGCCGTGGCACGCCTGGACCGTGTGCAACTGG
TACTGTTCCCACCCTTTACCTACCTGCCCGAGGCGCAGCGCCGCCTGGGCGCCAGCGGCATGGCCTGGGGCGCACAGAAC
GTCTCGGGGCATGAAGACGGTGCCTTCACCGGCGAAGTATCGGCCCAGATGTTGCGGGAGTTCGGCTGCGCCTGTGTGCT
GGTCGGCCACTCCGAGCGGCGCACGCTGTTCGGCGAGAACGACGCCGTCGTGGCGCGCAAGTTCCTTGCGGTCCGCCAAG
CCGGAATGACGCCGGTGCTGTGCGTCGGCGAGTCGCTGCCGGAGCGCGAGCAAGGTGCGACCGAGGATGTGGTGGCGCGC
CAGCTCCAGGCGGTGCTTGATCTGGCCGGGGCGAGTGCGTTTGCCGATGCGGTCGTGGCCTACGAGCCCGTGTGGGCGAT
CGGCACGGGCAAAACGGCCACACCCGCCCAGGCGCAGGACGTTCACGCCTTCATCCGTGGCCGACTGGCCGAGGCGGACC
CGGCCATCGCAGCGTCGCTGCACGTCCTTTACGGCGGCAGCATGAAGCGAGCGAACGCACGCGAGCTGCTCGCCATGCCC
GACATCGATGGCGGCCTGTTGGGCGGGGCGTCGCTGAACGTCGACGAGTTCATGGCCGTGGCCATCACGGCCCAGCGGCT
CGCGCAGGAGAACACTTAA

Upstream 100 bases:

>100_bases
TCATTGCCGGCGTGCCGTTCGGCACGCCCGGCACGACGAATCTCATGCGCATCGCGACGGTGTGAATCCAGTCCCTCTTA
ACAGACCAAAGAGCCCCCCG

Downstream 100 bases:

>100_bases
TGACGCAGGACGAGATCAAGGCCATGGTCGCCCGTGCGGCGCTGCCGCACGTGCTGCCCGGCAGCATCATCGGCGTGGGT
ACCGGATCGACGGTGAACCA

Product: triosephosphate isomerase (CbbJ)

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MDPTPLPPHPVRGQRRRLLVAGNWKMNGSLAGVQALAAAIADGAVARLDRVQLVLFPPFTYLPEAQRRLGASGMAWGAQN
VSGHEDGAFTGEVSAQMLREFGCACVLVGHSERRTLFGENDAVVARKFLAVRQAGMTPVLCVGESLPEREQGATEDVVAR
QLQAVLDLAGASAFADAVVAYEPVWAIGTGKTATPAQAQDVHAFIRGRLAEADPAIAASLHVLYGGSMKRANARELLAMP
DIDGGLLGGASLNVDEFMAVAITAQRLAQENT

Sequences:

>Translated_272_residues
MDPTPLPPHPVRGQRRRLLVAGNWKMNGSLAGVQALAAAIADGAVARLDRVQLVLFPPFTYLPEAQRRLGASGMAWGAQN
VSGHEDGAFTGEVSAQMLREFGCACVLVGHSERRTLFGENDAVVARKFLAVRQAGMTPVLCVGESLPEREQGATEDVVAR
QLQAVLDLAGASAFADAVVAYEPVWAIGTGKTATPAQAQDVHAFIRGRLAEADPAIAASLHVLYGGSMKRANARELLAMP
DIDGGLLGGASLNVDEFMAVAITAQRLAQENT
>Mature_272_residues
MDPTPLPPHPVRGQRRRLLVAGNWKMNGSLAGVQALAAAIADGAVARLDRVQLVLFPPFTYLPEAQRRLGASGMAWGAQN
VSGHEDGAFTGEVSAQMLREFGCACVLVGHSERRTLFGENDAVVARKFLAVRQAGMTPVLCVGESLPEREQGATEDVVAR
QLQAVLDLAGASAFADAVVAYEPVWAIGTGKTATPAQAQDVHAFIRGRLAEADPAIAASLHVLYGGSMKRANARELLAMP
DIDGGLLGGASLNVDEFMAVAITAQRLAQENT

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=247, Percent_Identity=42.914979757085, Blast_Score=188, Evalue=5e-48,
Organism=Homo sapiens, GI226529917, Length=247, Percent_Identity=42.914979757085, Blast_Score=187, Evalue=6e-48,
Organism=Escherichia coli, GI1790353, Length=254, Percent_Identity=49.2125984251969, Blast_Score=242, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17536593, Length=241, Percent_Identity=48.9626556016597, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320255, Length=239, Percent_Identity=42.6778242677824, Blast_Score=178, Evalue=8e-46,
Organism=Drosophila melanogaster, GI28572008, Length=251, Percent_Identity=45.4183266932271, Blast_Score=196, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28572006, Length=251, Percent_Identity=45.4183266932271, Blast_Score=196, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28572004, Length=247, Percent_Identity=45.748987854251, Blast_Score=196, Evalue=1e-50,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 28647; Mature: 28647

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPTPLPPHPVRGQRRRLLVAGNWKMNGSLAGVQALAAAIADGAVARLDRVQLVLFPPFT
CCCCCCCCCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCH
YLPEAQRRLGASGMAWGAQNVSGHEDGAFTGEVSAQMLREFGCACVLVGHSERRTLFGEN
HCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEECCCC
DAVVARKFLAVRQAGMTPVLCVGESLPEREQGATEDVVARQLQAVLDLAGASAFADAVVA
CHHHHHHHHHHHHCCCCEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
YEPVWAIGTGKTATPAQAQDVHAFIRGRLAEADPAIAASLHVLYGGSMKRANARELLAMP
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHEEHEEECCCCCCCCHHHEEECC
DIDGGLLGGASLNVDEFMAVAITAQRLAQENT
CCCCCEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDPTPLPPHPVRGQRRRLLVAGNWKMNGSLAGVQALAAAIADGAVARLDRVQLVLFPPFT
CCCCCCCCCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCH
YLPEAQRRLGASGMAWGAQNVSGHEDGAFTGEVSAQMLREFGCACVLVGHSERRTLFGEN
HCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEECCCC
DAVVARKFLAVRQAGMTPVLCVGESLPEREQGATEDVVARQLQAVLDLAGASAFADAVVA
CHHHHHHHHHHHHCCCCEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
YEPVWAIGTGKTATPAQAQDVHAFIRGRLAEADPAIAASLHVLYGGSMKRANARELLAMP
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHEEHEEECCCCCCCCHHHEEECC
DIDGGLLGGASLNVDEFMAVAITAQRLAQENT
CCCCCEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]