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The map label for this gene is dapC [H]

Identifier: 94310366

GI number: 94310366

Start: 1537892

End: 1539124

Strand: Reverse

Name: dapC [H]

Synonym: Rmet_1424

Alternate gene names: 94310366

Gene position: 1539124-1537892 (Counterclockwise)

Preceding gene: 94310367

Following gene: 94310365

Centisome position: 39.18

GC content: 67.8

Gene sequence:

>1233_bases
ATGCTGGGTTTCAACCGCCCCGCCGCTGCCACCGTGAATCCGCGCCTCGACCTGCTCCAAACCTATCCTTTCGAGAAACT
GCGCGCGCTGGTGGCCGATGTGAAACCGGCCGCCGTCCCGCCAATCAGCTTCGGCATCGGCGAACCCAAGCACCCCACTC
CGGCCTTCATCAAGGAAGCGATGACCGCGTCGCTCGGCGGCCTGGCCAACTACCCGAGCACCGCCGGCAGCGACGCGCTG
CGCGCGTGCATCGCGGGCTGGCTCGAACGCCGCTACAACCTGCCGAAGGTCGACGCCGCCACCGAGGTGCTGCCCGTCAC
CGGTTCGCGCGAGGCACTGTTCGCGTTCGCGCAGACCGTGATCGACAGCAGCAAGCCCAACCCGCTGGTGCTCTGCCCGA
ACCCGTTCTACCAGATCTATGAAGGCGCAGCCCTTCTGGCCGGCGCCCGTCCGGTGTTCGCCAACAGCGATCCGGCGCGC
AACTTCGCGCCGGCGTTCGACCAGATCGGCGCCGATGTGTGGCCGCACGTGCAACTGCTGTACGTCTGCTCGCCGGGTAA
CCCGACCGGCGCGGTGCTGTCGCTCGAAGACTGGAAGCAGCTTTTCGAATTGTCCGACCGCTATGGCTTCGTGATTGCCT
CCGACGAGTGCTACTCGGAGATCTACTTCGACGAAGCAAAGCCGCCGCTCGGCGCGCTCGAAGCGGCCCACAAGCTTGGC
CGGGGCCTGGAACGGCTGGTGATGTTCTCAAGCCTGTCGAAGCGCTCGAACGTGCCGGGCCTGCGCTCGGGCTTCGTCGC
CGGCGACCCCGAGATCCTGAAGAAATTCCTGCTCTACCGCACCTACCACGGCGCCGCGATGAACCCGGCCGTGCAGGCCG
CCAGCGCCGCGGCGTGGGGCGACGAGGCGCACGTGCGCGAGAACCGCGCGGCCTATGTGCGCAAATTCGCCGAGGTCACG
CCGATGCTGGCAGGGGTGCTCGACGTGGCCCTGCCCGATGCGGCGTTCTACCTGTGGGCCGATGTCTCGCGCACTGGTCT
GTCGGACACCGAGTTCGCCGTGCGGCTGCTGGCCGAACAGAACCTCACGGTGCTGCCCGGCAGCTACCTGGCCCGCGACG
CCCACGGCGTGAATCCCGGCGCGAACCGGGTCCGCATGGCGCTGGTGGCCACCCCGGACGAATGCCTCGAAGGCGCACGC
CGGATTGTCGAATTCTGCAAGTCGCTGGGCTGA

Upstream 100 bases:

>100_bases
GTGGCTGTGGTGTCGCGGGTGATGCTGTACTGATCTCCGGCGCCAGTCGGAGCGGATTTGCCGGATTCACGCGCGCGGCG
ATGGGCGGCATTCCTTTATA

Downstream 100 bases:

>100_bases
CCGGCGCGAACGCTTCACCCTGAATCACCGAATGTCCTGAAGCCGGAACGAGGATTTCCGGCATCACTCCCGATACATAT
TCACCACTGAGAACACAACC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLGFNRPAAATVNPRLDLLQTYPFEKLRALVADVKPAAVPPISFGIGEPKHPTPAFIKEAMTASLGGLANYPSTAGSDAL
RACIAGWLERRYNLPKVDAATEVLPVTGSREALFAFAQTVIDSSKPNPLVLCPNPFYQIYEGAALLAGARPVFANSDPAR
NFAPAFDQIGADVWPHVQLLYVCSPGNPTGAVLSLEDWKQLFELSDRYGFVIASDECYSEIYFDEAKPPLGALEAAHKLG
RGLERLVMFSSLSKRSNVPGLRSGFVAGDPEILKKFLLYRTYHGAAMNPAVQAASAAAWGDEAHVRENRAAYVRKFAEVT
PMLAGVLDVALPDAAFYLWADVSRTGLSDTEFAVRLLAEQNLTVLPGSYLARDAHGVNPGANRVRMALVATPDECLEGAR
RIVEFCKSLG

Sequences:

>Translated_410_residues
MLGFNRPAAATVNPRLDLLQTYPFEKLRALVADVKPAAVPPISFGIGEPKHPTPAFIKEAMTASLGGLANYPSTAGSDAL
RACIAGWLERRYNLPKVDAATEVLPVTGSREALFAFAQTVIDSSKPNPLVLCPNPFYQIYEGAALLAGARPVFANSDPAR
NFAPAFDQIGADVWPHVQLLYVCSPGNPTGAVLSLEDWKQLFELSDRYGFVIASDECYSEIYFDEAKPPLGALEAAHKLG
RGLERLVMFSSLSKRSNVPGLRSGFVAGDPEILKKFLLYRTYHGAAMNPAVQAASAAAWGDEAHVRENRAAYVRKFAEVT
PMLAGVLDVALPDAAFYLWADVSRTGLSDTEFAVRLLAEQNLTVLPGSYLARDAHGVNPGANRVRMALVATPDECLEGAR
RIVEFCKSLG
>Mature_410_residues
MLGFNRPAAATVNPRLDLLQTYPFEKLRALVADVKPAAVPPISFGIGEPKHPTPAFIKEAMTASLGGLANYPSTAGSDAL
RACIAGWLERRYNLPKVDAATEVLPVTGSREALFAFAQTVIDSSKPNPLVLCPNPFYQIYEGAALLAGARPVFANSDPAR
NFAPAFDQIGADVWPHVQLLYVCSPGNPTGAVLSLEDWKQLFELSDRYGFVIASDECYSEIYFDEAKPPLGALEAAHKLG
RGLERLVMFSSLSKRSNVPGLRSGFVAGDPEILKKFLLYRTYHGAAMNPAVQAASAAAWGDEAHVRENRAAYVRKFAEVT
PMLAGVLDVALPDAAFYLWADVSRTGLSDTEFAVRLLAEQNLTVLPGSYLARDAHGVNPGANRVRMALVATPDECLEGAR
RIVEFCKSLG

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=327, Percent_Identity=24.4648318042813, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI169881279, Length=327, Percent_Identity=24.4648318042813, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI56713254, Length=447, Percent_Identity=22.8187919463087, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI56713256, Length=429, Percent_Identity=22.8438228438228, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788722, Length=403, Percent_Identity=27.0471464019851, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788627, Length=161, Percent_Identity=27.9503105590062, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786816, Length=369, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=416, Percent_Identity=23.5576923076923, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=416, Percent_Identity=23.5576923076923, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44254; Mature: 44254

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGFNRPAAATVNPRLDLLQTYPFEKLRALVADVKPAAVPPISFGIGEPKHPTPAFIKEA
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
MTASLGGLANYPSTAGSDALRACIAGWLERRYNLPKVDAATEVLPVTGSREALFAFAQTV
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHH
IDSSKPNPLVLCPNPFYQIYEGAALLAGARPVFANSDPARNFAPAFDQIGADVWPHVQLL
HCCCCCCCEEECCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEE
YVCSPGNPTGAVLSLEDWKQLFELSDRYGFVIASDECYSEIYFDEAKPPLGALEAAHKLG
EEECCCCCCCEEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCCHHHHHHHHHHH
RGLERLVMFSSLSKRSNVPGLRSGFVAGDPEILKKFLLYRTYHGAAMNPAVQAASAAAWG
HHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
DEAHVRENRAAYVRKFAEVTPMLAGVLDVALPDAAFYLWADVSRTGLSDTEFAVRLLAEQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECHHHCCCCHHHHHHHHHHHC
NLTVLPGSYLARDAHGVNPGANRVRMALVATPDECLEGARRIVEFCKSLG
CCEECCCHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLGFNRPAAATVNPRLDLLQTYPFEKLRALVADVKPAAVPPISFGIGEPKHPTPAFIKEA
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
MTASLGGLANYPSTAGSDALRACIAGWLERRYNLPKVDAATEVLPVTGSREALFAFAQTV
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHH
IDSSKPNPLVLCPNPFYQIYEGAALLAGARPVFANSDPARNFAPAFDQIGADVWPHVQLL
HCCCCCCCEEECCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEE
YVCSPGNPTGAVLSLEDWKQLFELSDRYGFVIASDECYSEIYFDEAKPPLGALEAAHKLG
EEECCCCCCCEEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCCHHHHHHHHHHH
RGLERLVMFSSLSKRSNVPGLRSGFVAGDPEILKKFLLYRTYHGAAMNPAVQAASAAAWG
HHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
DEAHVRENRAAYVRKFAEVTPMLAGVLDVALPDAAFYLWADVSRTGLSDTEFAVRLLAEQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECHHHCCCCHHHHHHHHHHHC
NLTVLPGSYLARDAHGVNPGANRVRMALVATPDECLEGARRIVEFCKSLG
CCEECCCHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA