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The map label for this gene is patR [H]

Identifier: 94310249

GI number: 94310249

Start: 1419138

End: 1420982

Strand: Reverse

Name: patR [H]

Synonym: Rmet_1305

Alternate gene names: 94310249

Gene position: 1420982-1419138 (Counterclockwise)

Preceding gene: 94310250

Following gene: 94310247

Centisome position: 36.17

GC content: 53.12

Gene sequence:

>1845_bases
ATGAAGGAGGAGAAAGGGAAAGCGGGAGAAATAGACAGAGGAATACCGCTTTTCGTGCCAGATGTAGTGGCTGATCTGCA
TTTTCCGGACATTCGGGATCTGGCGGAACGGCTTCGTTTCAATCCTGCGGACGGTCGCATCTGGCTCGACGATCGTCGAA
TGGTCTTGATCCATACGGACGCGTTTGCTTCACTGCGACAGGAACTCATCGAAGCTTTAGGTAGCGATGCTGCGCGCGGA
TTGCTGACCCGCATGGGATATCTATCGGGTTCTCGGGATGCCGCGCTCGCACGAAAGGTTCGCGGGCAAGACAGCGCATT
TGATGCCTTCGCGGTAGGTCCTCAACTTCACGCCCTGGAAGGCATCGTCCTGGTAGAACCTGTCAGAGTGGATATCGACA
GCACCACCGGTCAGTATTACGGGGAATTTCTGTGGAAAGACTCGTCCGAGGATGAGGCTCACATATCCGTGTACGGCATC
GGCTCCGAACCAGCCTGCTGGATGCAGATTGGCTACGCGTGCGGCTACACGAGCGCTTTCATGGGCCGGCGTATTCTATA
CCGGGAAGTCGAATGCCGCGCGATGGGCAATACATTATGTCGAATCATTGGAAAGCCCGTGGACGAGTGGGACGCCCCCG
ATGCGGATCTTCGGTATATGCTGCCACAATCTCTGGAGAAACGTCGCTTTGTCGCGTTGAAAAGTTCAGGGCCAGCCCCG
ACTGACTCTACAGATCATGAGTGTGTGCCTTGCAAGCCTGACGAAGTGCCTGTCAAAGAAGGACCAATAGGGGCGTCTGC
TGGATTCAACGCAGTGATGCACAAAATATTCAGAGTGGCTCCCACTAGTGCGACCGTTTTACTGATGGGCGAGAGCGGCG
TGGGCAAAAGCCTGTTTGCTCGGGAACTGCACAACAGAAGTTCGCGTGTAGGGAAACCATTCGTTGAATTAAATTGTGCA
GCTCTTCCCGATTCGCTGATTGAATCGGAGCTTTTTGGTGTGGAGCGAGGGGCATTCACCGGCGCATCCGATGCCCGCGT
TGGGCGTTTCGAAAGCGCAAACGAAGGGACCATTTTTTTGGATGAGATTGGTAATCTCAGTCTAACCGCTCAAGCGAAGC
TATTGAGAGTTTTGCAAACGGGGGAGATGGAGCACCTCGGGAGTTCAAAGACGGTTAAGGTAAATGTTCGGGTAATTACT
GCGACTAATGACAACCTCAAACAGGCGATAAAAAGCGGGCGTTTTCGTGAGGATCTTTTCTACCGGCTGAATGTATTTCC
AATTGTTATTCCACCTTTGCGTGAAAGAAAGGATGATATCCCGGTTTTGCTGGAATTTTTCATAAAGAAATTTTCAAAAA
GGCATGGTCGGTCCCTCAAGGGCTTATCCAATCGTGCGCTTCATCTATTGCTGGATTACTCGTGGCCCGGGAATATCCGC
GAGATGGAAAATGTGCTCGAACGTGGCGTTATCCTCGCCGAGGAAGGCGGTACGCTCGATGTATGCCACTTGTTTAGTAG
CGGTGACACCGTGGAATGTAAGGGTGCTTTTGGTTTAAGCGACCTTGGGTCGCTTGCCCTCGATTCCATATCGACGAGCG
CTCCCCCCGAGACGATCCGCAAGAGCGGAGAAGCCCCGGAGGGGCTCGAGGATTGGGCAGCGCTTGCTGTACAGATGAAC
AAAGCGACACTTTGCGAGGTCGAAGATGCGCTCGTACGCGCGGCACTCAAAGCCGCGAACGGGAACATATCAGAAGCCGC
ACGTCTTCTCGGATTGACACGCGCGCAACTCGACTACCGTGTCAAGAAGTTGAACAATTCAATGCCAATCTCGACGGAGA
AGTAG

Upstream 100 bases:

>100_bases
TAGGTTTTCGTTCCAGGCAGGTTTACGCACCCGGTGAGAGCGTGCGAGACGATGAACTTTTAAGAAAGAGCCCTGACTGG
CGATTTCCTGAGGAGGGAAC

Downstream 100 bases:

>100_bases
AGAGCGCAAAGCACCAGCGTTTGGGATCAACCGAATCGAAGATCTGCTTCGGCTTTGTTCGGGAGGTTAGGGGCGCTGGT
GGTGCAGACGCAATTAGGCT

Product: transcriptional regulatory protein with helix-turn-helix motif, Fis-type

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MKEEKGKAGEIDRGIPLFVPDVVADLHFPDIRDLAERLRFNPADGRIWLDDRRMVLIHTDAFASLRQELIEALGSDAARG
LLTRMGYLSGSRDAALARKVRGQDSAFDAFAVGPQLHALEGIVLVEPVRVDIDSTTGQYYGEFLWKDSSEDEAHISVYGI
GSEPACWMQIGYACGYTSAFMGRRILYREVECRAMGNTLCRIIGKPVDEWDAPDADLRYMLPQSLEKRRFVALKSSGPAP
TDSTDHECVPCKPDEVPVKEGPIGASAGFNAVMHKIFRVAPTSATVLLMGESGVGKSLFARELHNRSSRVGKPFVELNCA
ALPDSLIESELFGVERGAFTGASDARVGRFESANEGTIFLDEIGNLSLTAQAKLLRVLQTGEMEHLGSSKTVKVNVRVIT
ATNDNLKQAIKSGRFREDLFYRLNVFPIVIPPLRERKDDIPVLLEFFIKKFSKRHGRSLKGLSNRALHLLLDYSWPGNIR
EMENVLERGVILAEEGGTLDVCHLFSSGDTVECKGAFGLSDLGSLALDSISTSAPPETIRKSGEAPEGLEDWAALAVQMN
KATLCEVEDALVRAALKAANGNISEAARLLGLTRAQLDYRVKKLNNSMPISTEK

Sequences:

>Translated_614_residues
MKEEKGKAGEIDRGIPLFVPDVVADLHFPDIRDLAERLRFNPADGRIWLDDRRMVLIHTDAFASLRQELIEALGSDAARG
LLTRMGYLSGSRDAALARKVRGQDSAFDAFAVGPQLHALEGIVLVEPVRVDIDSTTGQYYGEFLWKDSSEDEAHISVYGI
GSEPACWMQIGYACGYTSAFMGRRILYREVECRAMGNTLCRIIGKPVDEWDAPDADLRYMLPQSLEKRRFVALKSSGPAP
TDSTDHECVPCKPDEVPVKEGPIGASAGFNAVMHKIFRVAPTSATVLLMGESGVGKSLFARELHNRSSRVGKPFVELNCA
ALPDSLIESELFGVERGAFTGASDARVGRFESANEGTIFLDEIGNLSLTAQAKLLRVLQTGEMEHLGSSKTVKVNVRVIT
ATNDNLKQAIKSGRFREDLFYRLNVFPIVIPPLRERKDDIPVLLEFFIKKFSKRHGRSLKGLSNRALHLLLDYSWPGNIR
EMENVLERGVILAEEGGTLDVCHLFSSGDTVECKGAFGLSDLGSLALDSISTSAPPETIRKSGEAPEGLEDWAALAVQMN
KATLCEVEDALVRAALKAANGNISEAARLLGLTRAQLDYRVKKLNNSMPISTEK
>Mature_614_residues
MKEEKGKAGEIDRGIPLFVPDVVADLHFPDIRDLAERLRFNPADGRIWLDDRRMVLIHTDAFASLRQELIEALGSDAARG
LLTRMGYLSGSRDAALARKVRGQDSAFDAFAVGPQLHALEGIVLVEPVRVDIDSTTGQYYGEFLWKDSSEDEAHISVYGI
GSEPACWMQIGYACGYTSAFMGRRILYREVECRAMGNTLCRIIGKPVDEWDAPDADLRYMLPQSLEKRRFVALKSSGPAP
TDSTDHECVPCKPDEVPVKEGPIGASAGFNAVMHKIFRVAPTSATVLLMGESGVGKSLFARELHNRSSRVGKPFVELNCA
ALPDSLIESELFGVERGAFTGASDARVGRFESANEGTIFLDEIGNLSLTAQAKLLRVLQTGEMEHLGSSKTVKVNVRVIT
ATNDNLKQAIKSGRFREDLFYRLNVFPIVIPPLRERKDDIPVLLEFFIKKFSKRHGRSLKGLSNRALHLLLDYSWPGNIR
EMENVLERGVILAEEGGTLDVCHLFSSGDTVECKGAFGLSDLGSLALDSISTSAPPETIRKSGEAPEGLEDWAALAVQMN
KATLCEVEDALVRAALKAANGNISEAARLLGLTRAQLDYRVKKLNNSMPISTEK

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=359, Percent_Identity=41.2256267409471, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1788550, Length=332, Percent_Identity=41.566265060241, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87082117, Length=239, Percent_Identity=50.6276150627615, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1789087, Length=231, Percent_Identity=51.0822510822511, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1789233, Length=360, Percent_Identity=38.3333333333333, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87082152, Length=261, Percent_Identity=47.8927203065134, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI1790299, Length=347, Percent_Identity=40.6340057636888, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1788905, Length=214, Percent_Identity=48.5981308411215, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI87081872, Length=346, Percent_Identity=37.5722543352601, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786524, Length=256, Percent_Identity=42.578125, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787583, Length=228, Percent_Identity=41.2280701754386, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87081858, Length=243, Percent_Identity=34.156378600823, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=35.9375, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 67368; Mature: 67368

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEKGKAGEIDRGIPLFVPDVVADLHFPDIRDLAERLRFNPADGRIWLDDRRMVLIHTD
CCCCCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECH
AFASLRQELIEALGSDAARGLLTRMGYLSGSRDAALARKVRGQDSAFDAFAVGPQLHALE
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCHHHHC
GIVLVEPVRVDIDSTTGQYYGEFLWKDSSEDEAHISVYGIGSEPACWMQIGYACGYTSAF
CEEEEEEEEEEECCCCHHHHHHHEECCCCCCCCEEEEEECCCCCHHHHEECHHHCHHHHH
MGRRILYREVECRAMGNTLCRIIGKPVDEWDAPDADLRYMLPQSLEKRRFVALKSSGPAP
HCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHCHHHHCCCEEEEEECCCCCC
TDSTDHECVPCKPDEVPVKEGPIGASAGFNAVMHKIFRVAPTSATVLLMGESGVGKSLFA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
RELHNRSSRVGKPFVELNCAALPDSLIESELFGVERGAFTGASDARVGRFESANEGTIFL
HHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEE
DEIGNLSLTAQAKLLRVLQTGEMEHLGSSKTVKVNVRVITATNDNLKQAIKSGRFREDLF
ECCCCEEEHHHHHHHHHHHCCCHHHCCCCCEEEEEEEEEEECCHHHHHHHHCCCCHHHHH
YRLNVFPIVIPPLRERKDDIPVLLEFFIKKFSKRHGRSLKGLSNRALHLLLDYSWPGNIR
EEEEEEEEEECCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHH
EMENVLERGVILAEEGGTLDVCHLFSSGDTVECKGAFGLSDLGSLALDSISTSAPPETIR
HHHHHHHCCEEEEECCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHH
KSGEAPEGLEDWAALAVQMNKATLCEVEDALVRAALKAANGNISEAARLLGLTRAQLDYR
HCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VKKLNNSMPISTEK
HHHHCCCCCCCCCC
>Mature Secondary Structure
MKEEKGKAGEIDRGIPLFVPDVVADLHFPDIRDLAERLRFNPADGRIWLDDRRMVLIHTD
CCCCCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECH
AFASLRQELIEALGSDAARGLLTRMGYLSGSRDAALARKVRGQDSAFDAFAVGPQLHALE
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCHHHHC
GIVLVEPVRVDIDSTTGQYYGEFLWKDSSEDEAHISVYGIGSEPACWMQIGYACGYTSAF
CEEEEEEEEEEECCCCHHHHHHHEECCCCCCCCEEEEEECCCCCHHHHEECHHHCHHHHH
MGRRILYREVECRAMGNTLCRIIGKPVDEWDAPDADLRYMLPQSLEKRRFVALKSSGPAP
HCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHCHHHHCCCEEEEEECCCCCC
TDSTDHECVPCKPDEVPVKEGPIGASAGFNAVMHKIFRVAPTSATVLLMGESGVGKSLFA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
RELHNRSSRVGKPFVELNCAALPDSLIESELFGVERGAFTGASDARVGRFESANEGTIFL
HHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEE
DEIGNLSLTAQAKLLRVLQTGEMEHLGSSKTVKVNVRVITATNDNLKQAIKSGRFREDLF
ECCCCEEEHHHHHHHHHHHCCCHHHCCCCCEEEEEEEEEEECCHHHHHHHHCCCCHHHHH
YRLNVFPIVIPPLRERKDDIPVLLEFFIKKFSKRHGRSLKGLSNRALHLLLDYSWPGNIR
EEEEEEEEEECCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHH
EMENVLERGVILAEEGGTLDVCHLFSSGDTVECKGAFGLSDLGSLALDSISTSAPPETIR
HHHHHHHCCEEEEECCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHH
KSGEAPEGLEDWAALAVQMNKATLCEVEDALVRAALKAANGNISEAARLLGLTRAQLDYR
HCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VKKLNNSMPISTEK
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]