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The map label for this gene is boxC [H]

Identifier: 94310167

GI number: 94310167

Start: 1340607

End: 1342283

Strand: Reverse

Name: boxC [H]

Synonym: Rmet_1222

Alternate gene names: 94310167

Gene position: 1342283-1340607 (Counterclockwise)

Preceding gene: 94310168

Following gene: 94310166

Centisome position: 34.17

GC content: 66.49

Gene sequence:

>1677_bases
ATGTCGGACACCGCCCCCATCGCATCCAGCGCCCCCGTCACGTTCGAGCGCGATCCCGAGCAATACCGTCACTGGCAACT
TACGTTCGAGGGCCCCGTCGCCACGCTGGCGATGAACGTCGACGAGGAAGGCGGACTGCGCCCTGGCTATGCGCTGAAGC
TGAACTCCTATGACCTGGGCGTCGACATCGAACTGCACGATGCCCTGCAGCGCATTCGCTTCGAACATCCGGAAGTGCGC
ACCGTCGTGATGACGAGCACGAAAGATCGCATCTTCTGCTCGGGCGCCAACATCTTCATGCTCGGCAAGTCCAGCCACGC
CTGGAAGGTCAACTTCTGCAAGTTCACGAACGAGACCCGCAACGGTATCGAGGACGCCAGCCTCCACTCGGGCATCAAGT
TCATCGCCGCCTGCAACGGCACCACGGCGGGCGGCGGCTACGAGCTGGCGCTGGCCTGCGACGAGATCGTGCTGGTCGAC
GACCGCTCCTCGGCCGTGAGCCTGCCCGAAGTGCCGCTGCTGGGCGTGCTGCCGGGCACCGGCGGCCTGACGCGCGTCAC
CGACAAGCGCCATGTGCGCCGCGACCACGCCGACATCTTCTGCCTGACCACCGAAGGGGTGCGCGGGCAACGCGCCAAGG
ACTGGAAGCTTGTCGACGAGGTGGTCAAACCCGCACGCTTTGCCGAATACGTGCGCGAACGCGCGCAGGCGCTGGCCGCC
CAGAGCGACCGCCCCGCCGATGCACAGGGCGTGAGACTGACGCCACTGACGCGCACCGTGACGCCCGAAGGCTATCGGTA
CGAAACCGTACGCGTCGACATCGACCATGAGTCACGCCGCGCAACGATCACCGTGTCGGCGCCCGACGTCGGTCAACCCC
GGGATCTGGCCGGCATCCTCGCCGCCAGCGCCCAGTGGTGGCCGCTCAAGATGGCGCGCGAGCTAGACGACGCCATCCTG
ACGCTGCGCACCAATCATCTCGATATCGGCATGTGGATCCTCAAGACCACCGGCGATGCCGCACAGGTGCTGGCGGCCGA
TGCGCTGATGGATGCGCACGCCAGCCACTGGTTCGTGCGCGAGACGATCGGCATGCTGCGCCGCACGCTGGCGCGCCTGG
ATGTGTCGTCGCGCAGTCTGTTCGCGCTGGTGGAACCGGGCTCCTGCTTTGCCGGCACGCTGCTGGAACTGGTGCTGGCC
GCGGACCGCGCCTACATGCTGCAACTGCCCGACACGCCGGACGAAGCTCCTCGCGTTCATGCCGACGTCGCCAACTTCGG
CCGCTATCCGATGCCGAACGGCCTGACGCGCCTGGCCGCACGCTTCTATGAAGATGTCGACGCCATCGTCGCCGTGCGCG
AACAGGCCGGCAAGCCGCTAGACGGCCCCGCCGCCGAAGCACTTGGCCTGATCACGGCCGCGCTCGACGACATCGACTGG
GAAGACGAAATCCGTATCGCCACCGAGGAACGCGCGAGTCTGTCCCCCGACGCCCTGACCGGTCTGGAAGCCAACCTGCG
CTTCGGCGGGCGAGAAACGATGGAAACGCGCATTTTCGGGCGCCTGACGGCCTGGCAGAACTGGATCTTCAACCGGCCCA
ACGCGGTCGGCGAACACGGCGCGCTCAAGGTATTCGGCACCGGTAACAAGGCACGCTTCGACTGGGATCGGGTCTGA

Upstream 100 bases:

>100_bases
TCTTCGCAACGGGCTTGCACGATCTTGCATCGCCTCGATTGATGCACTATATTTCATGCCAGAAGATAAGGCACTATAGT
GCATCAAGGAGACAGCCCTC

Downstream 100 bases:

>100_bases
CGACTGTCCGATCTGACGGCAAATATAAAAGGAGACCCGCAATGAGCATCGACTACAGCCAGAAGATTCCGAACAACGTG
AACCTCTCCGAGGACCGCAC

Product: benzoyl-CoA-dihydrodiol lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSDTAPIASSAPVTFERDPEQYRHWQLTFEGPVATLAMNVDEEGGLRPGYALKLNSYDLGVDIELHDALQRIRFEHPEVR
TVVMTSTKDRIFCSGANIFMLGKSSHAWKVNFCKFTNETRNGIEDASLHSGIKFIAACNGTTAGGGYELALACDEIVLVD
DRSSAVSLPEVPLLGVLPGTGGLTRVTDKRHVRRDHADIFCLTTEGVRGQRAKDWKLVDEVVKPARFAEYVRERAQALAA
QSDRPADAQGVRLTPLTRTVTPEGYRYETVRVDIDHESRRATITVSAPDVGQPRDLAGILAASAQWWPLKMARELDDAIL
TLRTNHLDIGMWILKTTGDAAQVLAADALMDAHASHWFVRETIGMLRRTLARLDVSSRSLFALVEPGSCFAGTLLELVLA
ADRAYMLQLPDTPDEAPRVHADVANFGRYPMPNGLTRLAARFYEDVDAIVAVREQAGKPLDGPAAEALGLITAALDDIDW
EDEIRIATEERASLSPDALTGLEANLRFGGRETMETRIFGRLTAWQNWIFNRPNAVGEHGALKVFGTGNKARFDWDRV

Sequences:

>Translated_558_residues
MSDTAPIASSAPVTFERDPEQYRHWQLTFEGPVATLAMNVDEEGGLRPGYALKLNSYDLGVDIELHDALQRIRFEHPEVR
TVVMTSTKDRIFCSGANIFMLGKSSHAWKVNFCKFTNETRNGIEDASLHSGIKFIAACNGTTAGGGYELALACDEIVLVD
DRSSAVSLPEVPLLGVLPGTGGLTRVTDKRHVRRDHADIFCLTTEGVRGQRAKDWKLVDEVVKPARFAEYVRERAQALAA
QSDRPADAQGVRLTPLTRTVTPEGYRYETVRVDIDHESRRATITVSAPDVGQPRDLAGILAASAQWWPLKMARELDDAIL
TLRTNHLDIGMWILKTTGDAAQVLAADALMDAHASHWFVRETIGMLRRTLARLDVSSRSLFALVEPGSCFAGTLLELVLA
ADRAYMLQLPDTPDEAPRVHADVANFGRYPMPNGLTRLAARFYEDVDAIVAVREQAGKPLDGPAAEALGLITAALDDIDW
EDEIRIATEERASLSPDALTGLEANLRFGGRETMETRIFGRLTAWQNWIFNRPNAVGEHGALKVFGTGNKARFDWDRV
>Mature_557_residues
SDTAPIASSAPVTFERDPEQYRHWQLTFEGPVATLAMNVDEEGGLRPGYALKLNSYDLGVDIELHDALQRIRFEHPEVRT
VVMTSTKDRIFCSGANIFMLGKSSHAWKVNFCKFTNETRNGIEDASLHSGIKFIAACNGTTAGGGYELALACDEIVLVDD
RSSAVSLPEVPLLGVLPGTGGLTRVTDKRHVRRDHADIFCLTTEGVRGQRAKDWKLVDEVVKPARFAEYVRERAQALAAQ
SDRPADAQGVRLTPLTRTVTPEGYRYETVRVDIDHESRRATITVSAPDVGQPRDLAGILAASAQWWPLKMARELDDAILT
LRTNHLDIGMWILKTTGDAAQVLAADALMDAHASHWFVRETIGMLRRTLARLDVSSRSLFALVEPGSCFAGTLLELVLAA
DRAYMLQLPDTPDEAPRVHADVANFGRYPMPNGLTRLAARFYEDVDAIVAVREQAGKPLDGPAAEALGLITAALDDIDWE
DEIRIATEERASLSPDALTGLEANLRFGGRETMETRIFGRLTAWQNWIFNRPNAVGEHGALKVFGTGNKARFDWDRV

Specific function: Catalyzes the ring opening of 2,3-dihydro-2,3- dihydroxybenzoyl-CoA to form 3,4-dehydroadipyl-CoA semialdehyde [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the benzoyl-CoA oxygenase component C family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=294, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1788682, Length=201, Percent_Identity=33.8308457711443, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI221142681, Length=217, Percent_Identity=27.6497695852535, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=188, Percent_Identity=29.2553191489362, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017633
- InterPro:   IPR001753 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.2.44 [H]

Molecular weight: Translated: 61530; Mature: 61399

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTAPIASSAPVTFERDPEQYRHWQLTFEGPVATLAMNVDEEGGLRPGYALKLNSYDLG
CCCCCCCCCCCCEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCE
VDIELHDALQRIRFEHPEVRTVVMTSTKDRIFCSGANIFMLGKSSHAWKVNFCKFTNETR
EEEEHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCEEEECCCCCEEEEEEEEECCHHH
NGIEDASLHSGIKFIAACNGTTAGGGYELALACDEIVLVDDRSSAVSLPEVPLLGVLPGT
CCCCHHHHHCCEEEEEEECCCCCCCCEEEEEEECEEEEEECCCCCCCCCCCCEEEEECCC
GGLTRVTDKRHVRRDHADIFCLTTEGVRGQRAKDWKLVDEVVKPARFAEYVRERAQALAA
CCCEECCCHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
QSDRPADAQGVRLTPLTRTVTPEGYRYETVRVDIDHESRRATITVSAPDVGQPRDLAGIL
CCCCCCCCCCEEEECCEEECCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHH
AASAQWWPLKMARELDDAILTLRTNHLDIGMWILKTTGDAAQVLAADALMDAHASHWFVR
HCCCCCCHHHHHHHHCCEEEEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
ETIGMLRRTLARLDVSSRSLFALVEPGSCFAGTLLELVLAADRAYMLQLPDTPDEAPRVH
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEE
ADVANFGRYPMPNGLTRLAARFYEDVDAIVAVREQAGKPLDGPAAEALGLITAALDDIDW
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
EDEIRIATEERASLSPDALTGLEANLRFGGRETMETRIFGRLTAWQNWIFNRPNAVGEHG
CCCEEEEECCCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ALKVFGTGNKARFDWDRV
CEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SDTAPIASSAPVTFERDPEQYRHWQLTFEGPVATLAMNVDEEGGLRPGYALKLNSYDLG
CCCCCCCCCCCEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCE
VDIELHDALQRIRFEHPEVRTVVMTSTKDRIFCSGANIFMLGKSSHAWKVNFCKFTNETR
EEEEHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCEEEECCCCCEEEEEEEEECCHHH
NGIEDASLHSGIKFIAACNGTTAGGGYELALACDEIVLVDDRSSAVSLPEVPLLGVLPGT
CCCCHHHHHCCEEEEEEECCCCCCCCEEEEEEECEEEEEECCCCCCCCCCCCEEEEECCC
GGLTRVTDKRHVRRDHADIFCLTTEGVRGQRAKDWKLVDEVVKPARFAEYVRERAQALAA
CCCEECCCHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
QSDRPADAQGVRLTPLTRTVTPEGYRYETVRVDIDHESRRATITVSAPDVGQPRDLAGIL
CCCCCCCCCCEEEECCEEECCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHH
AASAQWWPLKMARELDDAILTLRTNHLDIGMWILKTTGDAAQVLAADALMDAHASHWFVR
HCCCCCCHHHHHHHHCCEEEEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
ETIGMLRRTLARLDVSSRSLFALVEPGSCFAGTLLELVLAADRAYMLQLPDTPDEAPRVH
HHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEE
ADVANFGRYPMPNGLTRLAARFYEDVDAIVAVREQAGKPLDGPAAEALGLITAALDDIDW
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
EDEIRIATEERASLSPDALTGLEANLRFGGRETMETRIFGRLTAWQNWIFNRPNAVGEHG
CCCEEEEECCCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ALKVFGTGNKARFDWDRV
CEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12399500 [H]