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The map label for this gene is ihfA [H]

Identifier: 94310111

GI number: 94310111

Start: 1277154

End: 1277564

Strand: Direct

Name: ihfA [H]

Synonym: Rmet_1166

Alternate gene names: 94310111

Gene position: 1277154-1277564 (Clockwise)

Preceding gene: 94310110

Following gene: 94310112

Centisome position: 32.51

GC content: 61.56

Gene sequence:

>411_bases
ATGAACGATCGAGACACGATTTCCATGAATGCTGCAGACCTGGGCGATGCAAGCGACCGGCACGCTGCCTCCCTCGACGA
CGCATCGCCGGAAGCCCGTGCCGCCGAGGTGCCTACCCTGACTAAAGCCGAACTTGCAGAGATGCTGTTCGATCAGGTTG
GCCTGAACAAGCGCGAATCGAAAGACATGGTCGAAGCGTTCTTCGACGTGATTCGAGAAGCGTTGGAGCGCGGCGACAGC
GTCAAGCTGTCAGGCTTCGGCAACTTCCAGTTGCGCGACAAGGCGCAACGTCCCGGCCGCAACCCCAAGACGGGAGAGAT
CATCCCGATCACGGCGCGCCGTGTGGTGACGTTCCACGCCAGCCAAAAGCTCAAGGCACAGGTGGAGGAGCGCGCGGGCC
TGGAAGCCTGA

Upstream 100 bases:

>100_bases
CCGCCTGCGCGCTTAAGCGAATCAGGCAGTCCACCTTCAATTGGAGCGCCCGGGCACAGCCCCCGGGCGGATCGCGGCAG
ATTTTACAGAGCGATCTAGG

Downstream 100 bases:

>100_bases
CGCGCGAGGGCATGTGCCGCACGGGCAGTATCGTCGCGGCAGCCACACATCTGTAACGACGCGCAACCGGGTGATTGCCC
GCGGCGATTGCAGTCTGTAT

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MNDRDTISMNAADLGDASDRHAASLDDASPEARAAEVPTLTKAELAEMLFDQVGLNKRESKDMVEAFFDVIREALERGDS
VKLSGFGNFQLRDKAQRPGRNPKTGEIIPITARRVVTFHASQKLKAQVEERAGLEA

Sequences:

>Translated_136_residues
MNDRDTISMNAADLGDASDRHAASLDDASPEARAAEVPTLTKAELAEMLFDQVGLNKRESKDMVEAFFDVIREALERGDS
VKLSGFGNFQLRDKAQRPGRNPKTGEIIPITARRVVTFHASQKLKAQVEERAGLEA
>Mature_136_residues
MNDRDTISMNAADLGDASDRHAASLDDASPEARAAEVPTLTKAELAEMLFDQVGLNKRESKDMVEAFFDVIREALERGDS
VKLSGFGNFQLRDKAQRPGRNPKTGEIIPITARRVVTFHASQKLKAQVEERAGLEA

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1788005, Length=90, Percent_Identity=72.2222222222222, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI1790433, Length=86, Percent_Identity=37.2093023255814, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1786644, Length=86, Percent_Identity=34.8837209302326, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 14941; Mature: 14941

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDRDTISMNAADLGDASDRHAASLDDASPEARAAEVPTLTKAELAEMLFDQVGLNKRES
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
KDMVEAFFDVIREALERGDSVKLSGFGNFQLRDKAQRPGRNPKTGEIIPITARRVVTFHA
HHHHHHHHHHHHHHHHCCCCEEECCCCCCEECCHHHCCCCCCCCCCEEEECCCEEEEECC
SQKLKAQVEERAGLEA
CHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDRDTISMNAADLGDASDRHAASLDDASPEARAAEVPTLTKAELAEMLFDQVGLNKRES
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
KDMVEAFFDVIREALERGDSVKLSGFGNFQLRDKAQRPGRNPKTGEIIPITARRVVTFHA
HHHHHHHHHHHHHHHHCCCCEEECCCCCCEECCHHHCCCCCCCCCCEEEECCCEEEEECC
SQKLKAQVEERAGLEA
CHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]