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The map label for this gene is atoD [H]

Identifier: 94310098

GI number: 94310098

Start: 1263128

End: 1263826

Strand: Direct

Name: atoD [H]

Synonym: Rmet_1153

Alternate gene names: 94310098

Gene position: 1263128-1263826 (Clockwise)

Preceding gene: 94310096

Following gene: 94310099

Centisome position: 32.16

GC content: 62.66

Gene sequence:

>699_bases
ATGAACAAGGTCTACGCCAGCGCTGCTGAGGCGCTCGCGGGCGTCGTACGCGACGGCCAGACGATCGCCGTGGGAGGTTT
CGGTCTGTGCGGCATCCCCGAAGCGCTGATCGCGGCACTGCGCGATAGCGGCGCCAAGCAGCTTACCTGCATCTCCAACA
ATGCTGGCGTCGATGGTTTTGGCCTCGGCCTGCTGCTTGCCACGCGGCAGATCCGCAAGATGATCTCGTCCTACGTGGGC
GAGAACAAGGAGTTCGAGCGCCAATACCTGGCTGGCGAACTCGAGCTCGAATTCACGCCGCAGGGCACGCTGGCCGAGAA
GCTGCGCGCCGGCGGATCGGGTATCCCGGCGTTCTTCACCAAGACCGGCGTGGGCACGATCGTCGCGGATGGCAAGGAAA
TCCGCGAATTCGACGGCCAGCAATACGTGATGGAGCGTTCGCTGACGGCAGACGTGGCGCTGGTCAAGGCCAAGAAGGCT
GACAAGGCAGGCAATCTGGTCTTCCGCCGCACCGCCCGCAACTTCAACCCGGTTTGCGCAATGGCCGGAAAGATCACGGT
GGTCGAGGTGGAAGAGATCGTTGAAACCGGTGAGATCGATCCGGACGACGTCCACCTGCCGGGCATCTTCGTGCACCGCA
TCGTGCTGAACACGAACCCCGAAAAACGCATCGAACAGCGCACCGTGCGTGCCAAGTAA

Upstream 100 bases:

>100_bases
TACAGATTCCGCGTGTGGCCGGTTGGCCATGTGGCGGACCAAGAACGTCGTCGGAAGGCTTCGAACCATCCGCGCGGGAC
TACCGAGGAAGGAGCAAACA

Downstream 100 bases:

>100_bases
GGAGACAGATCATGGCATGGACACGTGATGAAATGGCCGCGCGCGCGGCCCGGGAACTGCAGGACGGTTTCTATGTGAAC
CTCGGTATCGGCCTGCCGAC

Product: acetyl-CoA:acetoacetyl-CoA transferase, subunit alpha

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGAKQLTCISNNAGVDGFGLGLLLATRQIRKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTKTGVGTIVADGKEIREFDGQQYVMERSLTADVALVKAKKA
DKAGNLVFRRTARNFNPVCAMAGKITVVEVEEIVETGEIDPDDVHLPGIFVHRIVLNTNPEKRIEQRTVRAK

Sequences:

>Translated_232_residues
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGAKQLTCISNNAGVDGFGLGLLLATRQIRKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTKTGVGTIVADGKEIREFDGQQYVMERSLTADVALVKAKKA
DKAGNLVFRRTARNFNPVCAMAGKITVVEVEEIVETGEIDPDDVHLPGIFVHRIVLNTNPEKRIEQRTVRAK
>Mature_232_residues
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGAKQLTCISNNAGVDGFGLGLLLATRQIRKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTKTGVGTIVADGKEIREFDGQQYVMERSLTADVALVKAKKA
DKAGNLVFRRTARNFNPVCAMAGKITVVEVEEIVETGEIDPDDVHLPGIFVHRIVLNTNPEKRIEQRTVRAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=56.2753036437247, Blast_Score=284, Evalue=4e-77,
Organism=Homo sapiens, GI11545841, Length=246, Percent_Identity=54.0650406504065, Blast_Score=246, Evalue=2e-65,
Organism=Escherichia coli, GI1788551, Length=205, Percent_Identity=44.390243902439, Blast_Score=195, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17531517, Length=245, Percent_Identity=57.1428571428571, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=53.7190082644628, Blast_Score=258, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=53.7190082644628, Blast_Score=258, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 24953; Mature: 24953

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGAKQLTCISNNAGVDGF
CCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHH
GLGLLLATRQIRKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTIVADGKEIREFDGQQYVMERSLTADVALVKAKKADKAGNLVFRRTARNFNPVCA
HCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKITVVEVEEIVETGEIDPDDVHLPGIFVHRIVLNTNPEKRIEQRTVRAK
HCCCEEEEEHHHHHHHCCCCCCCEECCHHEEEEEEECCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGAKQLTCISNNAGVDGF
CCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHH
GLGLLLATRQIRKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTIVADGKEIREFDGQQYVMERSLTADVALVKAKKADKAGNLVFRRTARNFNPVCA
HCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKITVVEVEEIVETGEIDPDDVHLPGIFVHRIVLNTNPEKRIEQRTVRAK
HCCCEEEEEHHHHHHHCCCCCCCEECCHHEEEEEEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]