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The map label for this gene is yebK [H]

Identifier: 94309989

GI number: 94309989

Start: 1135746

End: 1136762

Strand: Reverse

Name: yebK [H]

Synonym: Rmet_1044

Alternate gene names: 94309989

Gene position: 1136762-1135746 (Counterclockwise)

Preceding gene: 94310002

Following gene: 94309984

Centisome position: 28.94

GC content: 66.96

Gene sequence:

>1017_bases
ATGCGCGACAGAATCCTTGCCGTCTACGACTCGCTACGCCCGTCCGAACGCCGCCTGGCCGATTACGTGGCACGACACGG
TGCGAGCGTCATCCGACTGACCATGCCGGAACTGGCGGACCGGGCCGGCGTCTCGCAGCCGACGATCGCCCGCTTCTGCG
CCGCGCTTGGCTACGACGGCTTCAAGGAGTTCAAGCTTCAGTTCGCACAGAATGTGGGGGGTGGCACGCCCTTCGTTCAC
CAGGACGTGGAAGCCGACGATCGGCCCGCCGATATCGCCGGCAAGGTGTTCGACCGCACCATCGCCACGCTGATGTCCGT
GCGAAACGCACTGTCCGCCGACCAGATCGAGCACGGTATCCGGCTACTGGCCGGGGCGCGCCGCATCGAGTTTTATGGCT
GCGGCAACTCGGGCATCGTTGCGCTCGACATCCAGCACAAATTCTTCCGCCTGGGCATTCCCACCACGGCTTACTCGGAC
CCGCACGTGTTCAGCATGTCCGCAGCGCTGCTGCGTCCGGGCGATGTCGCCGTGCTGGTGTCCAACAGCGGCCGCACATG
GGACATGCTCACCGCCGCCACTCTGGCACGCAGCAGCGGCGCCAGCGTGCTGGCGCTGACCCATAGCGGATCACCGCTCG
CCCGCCTTGCGGACGTCTGCGTCTTCTCCGACGTCGAAGAGGACAGCGAGGTCTATACGCCCATGACTTCGCGCATCTGC
CATCTCGTGCTCGGCGACGTGCTGGCCGCAGGCGTGGCGCTAGATCGTGCCGACTCGGTCGCCGCAGGCCTGCAGCGAGC
CAAGGCACATCTGCGCGAGCGCCGGATTGCGGGTGCCGATCCGGCGCCGCTGGGCAAGACCCCAGCAGCGGCCTCGGCCA
CAACTGCATCCGAGGCGACATCACAGTCAATCAAACCGAGCCGGGCGGCGCGTCGCCCGACTAAGTCCGACAGCCCTGCC
AACAAGACGACCAAGCCCGCCGCTCACCGTGGCGCGGGCGGCGCGTCTCGCCAATAA

Upstream 100 bases:

>100_bases
AATCTCTACATTACCGAGGCTGCACTGAAGCCAGCCCAGGGGCACCGGCACAACCGGCGCCCCCCCAATACCCTTACGCA
CGATCCCGCACTCCCTCACC

Downstream 100 bases:

>100_bases
CGGCGCTGTTGCTGACGGAACGACGTCACCACGTAGTCGCCGCCGCCCGTGACGATCGACACCGCGCCGGTTTCATCGGT
GCGATACCGCGCCGCGCCCG

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Glucokinase; Glucose kinase; Putative HTH-type transcriptional regulator [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRDRILAVYDSLRPSERRLADYVARHGASVIRLTMPELADRAGVSQPTIARFCAALGYDGFKEFKLQFAQNVGGGTPFVH
QDVEADDRPADIAGKVFDRTIATLMSVRNALSADQIEHGIRLLAGARRIEFYGCGNSGIVALDIQHKFFRLGIPTTAYSD
PHVFSMSAALLRPGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLARLADVCVFSDVEEDSEVYTPMTSRIC
HLVLGDVLAAGVALDRADSVAAGLQRAKAHLRERRIAGADPAPLGKTPAAASATTASEATSQSIKPSRAARRPTKSDSPA
NKTTKPAAHRGAGGASRQ

Sequences:

>Translated_338_residues
MRDRILAVYDSLRPSERRLADYVARHGASVIRLTMPELADRAGVSQPTIARFCAALGYDGFKEFKLQFAQNVGGGTPFVH
QDVEADDRPADIAGKVFDRTIATLMSVRNALSADQIEHGIRLLAGARRIEFYGCGNSGIVALDIQHKFFRLGIPTTAYSD
PHVFSMSAALLRPGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLARLADVCVFSDVEEDSEVYTPMTSRIC
HLVLGDVLAAGVALDRADSVAAGLQRAKAHLRERRIAGADPAPLGKTPAAASATTASEATSQSIKPSRAARRPTKSDSPA
NKTTKPAAHRGAGGASRQ
>Mature_338_residues
MRDRILAVYDSLRPSERRLADYVARHGASVIRLTMPELADRAGVSQPTIARFCAALGYDGFKEFKLQFAQNVGGGTPFVH
QDVEADDRPADIAGKVFDRTIATLMSVRNALSADQIEHGIRLLAGARRIEFYGCGNSGIVALDIQHKFFRLGIPTTAYSD
PHVFSMSAALLRPGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLARLADVCVFSDVEEDSEVYTPMTSRIC
HLVLGDVLAAGVALDRADSVAAGLQRAKAHLRERRIAGADPAPLGKTPAAASATTASEATSQSIKPSRAARRPTKSDSPA
NKTTKPAAHRGAGGASRQ

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=277, Percent_Identity=39.7111913357401, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI87082369, Length=261, Percent_Identity=30.2681992337165, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082130, Length=243, Percent_Identity=27.9835390946502, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788767, Length=263, Percent_Identity=25.4752851711027, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836
- InterPro:   IPR000843
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02685 Glucokinase; PF01418 HTH_6; PF01380 SIS [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35817; Mature: 35817

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDRILAVYDSLRPSERRLADYVARHGASVIRLTMPELADRAGVSQPTIARFCAALGYDG
CCCCEEHHHHCCCCHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCHHHHHHHHHHCCCC
FKEFKLQFAQNVGGGTPFVHQDVEADDRPADIAGKVFDRTIATLMSVRNALSADQIEHGI
HHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLAGARRIEFYGCGNSGIVALDIQHKFFRLGIPTTAYSDPHVFSMSAALLRPGDVAVLV
HHHHCCCEEEEEECCCCCEEEEEECCEEEEECCCCCCCCCCCCEEHHHHHCCCCCEEEEE
SNSGRTWDMLTAATLARSSGASVLALTHSGSPLARLADVCVFSDVEEDSEVYTPMTSRIC
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHCHHHHHHH
HLVLGDVLAAGVALDRADSVAAGLQRAKAHLRERRIAGADPAPLGKTPAAASATTASEAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
SQSIKPSRAARRPTKSDSPANKTTKPAAHRGAGGASRQ
HHCCCCHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MRDRILAVYDSLRPSERRLADYVARHGASVIRLTMPELADRAGVSQPTIARFCAALGYDG
CCCCEEHHHHCCCCHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCHHHHHHHHHHCCCC
FKEFKLQFAQNVGGGTPFVHQDVEADDRPADIAGKVFDRTIATLMSVRNALSADQIEHGI
HHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLAGARRIEFYGCGNSGIVALDIQHKFFRLGIPTTAYSDPHVFSMSAALLRPGDVAVLV
HHHHCCCEEEEEECCCCCEEEEEECCEEEEECCCCCCCCCCCCEEHHHHHCCCCCEEEEE
SNSGRTWDMLTAATLARSSGASVLALTHSGSPLARLADVCVFSDVEEDSEVYTPMTSRIC
CCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHCHHHHHHH
HLVLGDVLAAGVALDRADSVAAGLQRAKAHLRERRIAGADPAPLGKTPAAASATTASEAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
SQSIKPSRAARRPTKSDSPANKTTKPAAHRGAGGASRQ
HHCCCCHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA