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The map label for this gene is lolE [H]

Identifier: 94309985

GI number: 94309985

Start: 1130222

End: 1131472

Strand: Direct

Name: lolE [H]

Synonym: Rmet_1040

Alternate gene names: 94309985

Gene position: 1130222-1131472 (Clockwise)

Preceding gene: 94309982

Following gene: 94309986

Centisome position: 28.77

GC content: 63.55

Gene sequence:

>1251_bases
TTGAACTTTCCTTACGAATGGCAGATCGGCTGGCGCTACACCCGCGCGAGCAAGCGCGCCAGCCGCAATACGTTCATTTC
ATTCATTTCGATGATTTCGATGATGGGCATCGCGCTTGGCGTGGCCGCCCTGATCGTCGTGCTCTCGGTCATGAACGGCT
TCCAGAAGGAAGTGCGCGATCGGATGCTGTCGGTGCTGTCGCACATCGAAGTCATCGGCGCCGCGCCGCTGACGGACTGG
CAGAAGACGGCCGCCGAGGCCCTGCGCAACAAGGAAGTGGTGGGCGCCGCGCCGTATGTGGCGGCCCAGGCCATGATGAC
GCGGGAAGACGTGGTGCGCGGCGTGCTGCTGCGCGGCGTGGACCCCGCCGAAGAGCCCAAGGTGTCGGATATCGCCAACC
AATTTCGCGCCGGCAGCATGAACGCGCTGGCGCCGGGTGGGTTCGGCATCGCACTCGGCAGTGAACTGGCCAATGCACTG
GGCGTGCGCGTGGGCGACAAGGTGATGCTGGTGGTGCCGCAAGGCACGATCACGCCGGCCGGAATGCTGCCGCGCCTCAA
GCAGTTCACCGTGGCCGGCGTGTTCTCGTCGGGTCACTACGAGTTCGATAGCGCGCTGGCGCTGATCAACATCGGCGATG
CGGAAACGCTGTTCCGCCAGAGCGGACCCACGGGCGTGCGACTGAAACTGCAGGACATGCAGCGCGCGCCGCAGGTGGCC
CAGGAGCTGGCGGGCACCATGAGCGGCGACCTCTACCTGCGCGACTGGTCGAAGCAGAACCGCAACTGGTTCGCCGCCGT
GCAGACCGAAAAGCGCATGATGTTCATCATCCTGACGCTGATCATCGCCGTGGCCGCGTTCAACCTGGTGTCCACGCTGG
TCATGACCGTGACTGACAAGCAGGCCGACATCGCGATCCTGCGCACGATGGGCGCCCAGCCGCGCTCGATCATGAAGATC
TTCATCGTTCAAGGCGTGGCCATCGGCTTCATCGGCACCTTGCTCGGCGTATTGGGCGGCACGCTGATCGCCACCAATAT
CGACGTGATCGTGCCTTTCATCGAGCGGATCCTGCATGTGCAGTTCCTGCCCAAGGACATCTACTTCATTAGCGAATTGC
CTTCGGACCCGCGCATGAACGACATCGCTACCATCGGTATCATTTCCTTCGTGCTGGCGTCGCTGGCCACGATCTACCCG
AGCTGGCGCGCCTCGCGCGTGAACCCGGCGGAGGCGCTGCGCTATGAGTGA

Upstream 100 bases:

>100_bases
TGGCGAGATTGTAAACTCCCGGCTGGCCGGCGCCAGTTTCCCGTGACCGGATAACCGATAAACTGCCGTCGGCGCTTTTC
CTCGAACAACAGGACTCCTC

Downstream 100 bases:

>100_bases
TACGACGCTGCTCCCCGAAGCCTCATTCCAGGCCGGCACCCAAGGCCCTGGCACGCCAACCGGCACGCCGGTCCTGCTGG
GCGAGGGCCTGACCAAGCGT

Product: outer membrane-specific lipoprotein ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNFPYEWQIGWRYTRASKRASRNTFISFISMISMMGIALGVAALIVVLSVMNGFQKEVRDRMLSVLSHIEVIGAAPLTDW
QKTAAEALRNKEVVGAAPYVAAQAMMTREDVVRGVLLRGVDPAEEPKVSDIANQFRAGSMNALAPGGFGIALGSELANAL
GVRVGDKVMLVVPQGTITPAGMLPRLKQFTVAGVFSSGHYEFDSALALINIGDAETLFRQSGPTGVRLKLQDMQRAPQVA
QELAGTMSGDLYLRDWSKQNRNWFAAVQTEKRMMFIILTLIIAVAAFNLVSTLVMTVTDKQADIAILRTMGAQPRSIMKI
FIVQGVAIGFIGTLLGVLGGTLIATNIDVIVPFIERILHVQFLPKDIYFISELPSDPRMNDIATIGIISFVLASLATIYP
SWRASRVNPAEALRYE

Sequences:

>Translated_416_residues
MNFPYEWQIGWRYTRASKRASRNTFISFISMISMMGIALGVAALIVVLSVMNGFQKEVRDRMLSVLSHIEVIGAAPLTDW
QKTAAEALRNKEVVGAAPYVAAQAMMTREDVVRGVLLRGVDPAEEPKVSDIANQFRAGSMNALAPGGFGIALGSELANAL
GVRVGDKVMLVVPQGTITPAGMLPRLKQFTVAGVFSSGHYEFDSALALINIGDAETLFRQSGPTGVRLKLQDMQRAPQVA
QELAGTMSGDLYLRDWSKQNRNWFAAVQTEKRMMFIILTLIIAVAAFNLVSTLVMTVTDKQADIAILRTMGAQPRSIMKI
FIVQGVAIGFIGTLLGVLGGTLIATNIDVIVPFIERILHVQFLPKDIYFISELPSDPRMNDIATIGIISFVLASLATIYP
SWRASRVNPAEALRYE
>Mature_416_residues
MNFPYEWQIGWRYTRASKRASRNTFISFISMISMMGIALGVAALIVVLSVMNGFQKEVRDRMLSVLSHIEVIGAAPLTDW
QKTAAEALRNKEVVGAAPYVAAQAMMTREDVVRGVLLRGVDPAEEPKVSDIANQFRAGSMNALAPGGFGIALGSELANAL
GVRVGDKVMLVVPQGTITPAGMLPRLKQFTVAGVFSSGHYEFDSALALINIGDAETLFRQSGPTGVRLKLQDMQRAPQVA
QELAGTMSGDLYLRDWSKQNRNWFAAVQTEKRMMFIILTLIIAVAAFNLVSTLVMTVTDKQADIAILRTMGAQPRSIMKI
FIVQGVAIGFIGTLLGVLGGTLIATNIDVIVPFIERILHVQFLPKDIYFISELPSDPRMNDIATIGIISFVLASLATIYP
SWRASRVNPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=33.6538461538462, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1787360, Length=412, Percent_Identity=35.1941747572816, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45395; Mature: 45395

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPYEWQIGWRYTRASKRASRNTFISFISMISMMGIALGVAALIVVLSVMNGFQKEVRD
CCCCEEEEECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLSHIEVIGAAPLTDWQKTAAEALRNKEVVGAAPYVAAQAMMTREDVVRGVLLRGV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DPAEEPKVSDIANQFRAGSMNALAPGGFGIALGSELANALGVRVGDKVMLVVPQGTITPA
CCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
GMLPRLKQFTVAGVFSSGHYEFDSALALINIGDAETLFRQSGPTGVRLKLQDMQRAPQVA
HHHHHHHHHHHHEEECCCCEECCCEEEEEECCCHHHHHHCCCCCCEEEEHHHHHHHHHHH
QELAGTMSGDLYLRDWSKQNRNWFAAVQTEKRMMFIILTLIIAVAAFNLVSTLVMTVTDK
HHHHHHCCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QADIAILRTMGAQPRSIMKIFIVQGVAIGFIGTLLGVLGGTLIATNIDVIVPFIERILHV
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QFLPKDIYFISELPSDPRMNDIATIGIISFVLASLATIYPSWRASRVNPAEALRYE
HHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MNFPYEWQIGWRYTRASKRASRNTFISFISMISMMGIALGVAALIVVLSVMNGFQKEVRD
CCCCEEEEECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLSHIEVIGAAPLTDWQKTAAEALRNKEVVGAAPYVAAQAMMTREDVVRGVLLRGV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DPAEEPKVSDIANQFRAGSMNALAPGGFGIALGSELANALGVRVGDKVMLVVPQGTITPA
CCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
GMLPRLKQFTVAGVFSSGHYEFDSALALINIGDAETLFRQSGPTGVRLKLQDMQRAPQVA
HHHHHHHHHHHHEEECCCCEECCCEEEEEECCCHHHHHHCCCCCCEEEEHHHHHHHHHHH
QELAGTMSGDLYLRDWSKQNRNWFAAVQTEKRMMFIILTLIIAVAAFNLVSTLVMTVTDK
HHHHHHCCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QADIAILRTMGAQPRSIMKIFIVQGVAIGFIGTLLGVLGGTLIATNIDVIVPFIERILHV
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
QFLPKDIYFISELPSDPRMNDIATIGIISFVLASLATIYPSWRASRVNPAEALRYE
HHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]