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The map label for this gene is nadK [H]

Identifier: 94309944

GI number: 94309944

Start: 1091040

End: 1091981

Strand: Reverse

Name: nadK [H]

Synonym: Rmet_0999

Alternate gene names: 94309944

Gene position: 1091981-1091040 (Counterclockwise)

Preceding gene: 94309948

Following gene: 94309943

Centisome position: 27.8

GC content: 65.82

Gene sequence:

>942_bases
ATGCCGGTATGGTCTAATCCCGGCATGTCTGCCCCCCACAAGACCGGCGCCGCGCGCCCCCCGTTCAAGACTGTAGCCCT
GGTGGGCCGACATTCGACCGCTGGCATCGAAGGTCCGCTGGAAGAACTCGCGTCTTGCATCTCCCGTAACGGACAGGATG
TGGTGTTCGAACGCGAAACCGCAATGGCTACCGGGCTGACAGGTTACCCGGTGCTGACCCCCGACGAGATCGGCCGCGAA
GCTGATGTGGCGGTGGTGCTGGGCGGCGACGGGACGCTGCTCGGGCTGGCCCGCCAGCTAGCCGGGCACGATGTGCCGGT
GATCGGCGTCAACCACGGCCGGCTGGGCTTTATGACCGACATCCCGCTCGATGCCATCTCCACGGCACTGCCCGAGATGC
TGTCCGGCCGGTATGAGGCCGAAACCCGGATGCTGCTGGAGTCGCGCGTGATCCGCGACGACTCGGTGATTTTCTCCGCG
CTGGCGTTCAACGATGTGGTGGTGAACCGCTCGGGGATCTCCGGCATGGTCGAACTGGCGGTCTCGGTCGACGGCTATTT
CATGTACAACCAGCGCTCGGACGGCCTGATCGTCTCCACGCCCACCGGCTCCACCGCCTACGCGCTGGCCGCGGGGGGTC
CGATCCTGCACCCGACGCTGTCCGGCCTGGTGCTGGTGCCGATCGCGCCACACGCGCTGTCGAACCGGCCCATCGTGCTG
CCGTACGACGCCGAGGTCACGATCGAAGTGGCCAGCGCGCGCGATGTCAGCGTCAACTTCGACATGCAGGCGCTGGCCTC
GCTGCTGCCCGGCGACCGCATCGTGGTACGCCGTTCGGCCAAGACCATCAACCTGCTGCACCCAGTGGGATATAACTACT
ACGCCACACTGCGCAAGAAGCTGCACTGGCACGAGTATCCGACCGAAGACAACCGGCTCTGA

Upstream 100 bases:

>100_bases
AAGCTTTTTTGAACGTTCGTCCATGATGCCCCGATTTTAATCAAACTTTGGCGGTTCAGGCGTCACCTGGAGCGGCGGCG
GCCCAGTGCTGACAACGATC

Downstream 100 bases:

>100_bases
TCCGCAGACGCCTCAACGTTCCGTCCTGATCCTCGTTACCCGACCTTACCGCCCTTACCCGCCACCGCTCACCGCCCACG
ATGCTGCGCAGCCTCTCGAT

Product: NAD(+)/NADH kinase family protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPVWSNPGMSAPHKTGAARPPFKTVALVGRHSTAGIEGPLEELASCISRNGQDVVFERETAMATGLTGYPVLTPDEIGRE
ADVAVVLGGDGTLLGLARQLAGHDVPVIGVNHGRLGFMTDIPLDAISTALPEMLSGRYEAETRMLLESRVIRDDSVIFSA
LAFNDVVVNRSGISGMVELAVSVDGYFMYNQRSDGLIVSTPTGSTAYALAAGGPILHPTLSGLVLVPIAPHALSNRPIVL
PYDAEVTIEVASARDVSVNFDMQALASLLPGDRIVVRRSAKTINLLHPVGYNYYATLRKKLHWHEYPTEDNRL

Sequences:

>Translated_313_residues
MPVWSNPGMSAPHKTGAARPPFKTVALVGRHSTAGIEGPLEELASCISRNGQDVVFERETAMATGLTGYPVLTPDEIGRE
ADVAVVLGGDGTLLGLARQLAGHDVPVIGVNHGRLGFMTDIPLDAISTALPEMLSGRYEAETRMLLESRVIRDDSVIFSA
LAFNDVVVNRSGISGMVELAVSVDGYFMYNQRSDGLIVSTPTGSTAYALAAGGPILHPTLSGLVLVPIAPHALSNRPIVL
PYDAEVTIEVASARDVSVNFDMQALASLLPGDRIVVRRSAKTINLLHPVGYNYYATLRKKLHWHEYPTEDNRL
>Mature_312_residues
PVWSNPGMSAPHKTGAARPPFKTVALVGRHSTAGIEGPLEELASCISRNGQDVVFERETAMATGLTGYPVLTPDEIGREA
DVAVVLGGDGTLLGLARQLAGHDVPVIGVNHGRLGFMTDIPLDAISTALPEMLSGRYEAETRMLLESRVIRDDSVIFSAL
AFNDVVVNRSGISGMVELAVSVDGYFMYNQRSDGLIVSTPTGSTAYALAAGGPILHPTLSGLVLVPIAPHALSNRPIVLP
YDAEVTIEVASARDVSVNFDMQALASLLPGDRIVVRRSAKTINLLHPVGYNYYATLRKKLHWHEYPTEDNRL

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=325, Percent_Identity=29.2307692307692, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1788968, Length=285, Percent_Identity=41.7543859649123, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=30.5785123966942, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=30.4166666666667, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6325068, Length=217, Percent_Identity=31.7972350230415, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28573828, Length=252, Percent_Identity=32.9365079365079, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28573832, Length=252, Percent_Identity=32.5396825396825, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28573830, Length=252, Percent_Identity=32.5396825396825, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI161077047, Length=252, Percent_Identity=32.9365079365079, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28573826, Length=252, Percent_Identity=32.9365079365079, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129957, Length=284, Percent_Identity=30.2816901408451, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363323, Length=284, Percent_Identity=30.2816901408451, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363321, Length=284, Percent_Identity=30.2816901408451, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24653422, Length=284, Percent_Identity=30.2816901408451, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24653424, Length=284, Percent_Identity=30.2816901408451, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33534; Mature: 33403

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVWSNPGMSAPHKTGAARPPFKTVALVGRHSTAGIEGPLEELASCISRNGQDVVFERET
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCH
AMATGLTGYPVLTPDEIGREADVAVVLGGDGTLLGLARQLAGHDVPVIGVNHGRLGFMTD
HHHCCCCCCCEECHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEC
IPLDAISTALPEMLSGRYEAETRMLLESRVIRDDSVIFSALAFNDVVVNRSGISGMVELA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHEEHHHHHCEEEEECCCCCCEEEEE
VSVDGYFMYNQRSDGLIVSTPTGSTAYALAAGGPILHPTLSGLVLVPIAPHALSNRPIVL
EEECEEEEEECCCCCEEEECCCCCCEEEEECCCCEECCCCCCEEEEEECCHHCCCCCEEE
PYDAEVTIEVASARDVSVNFDMQALASLLPGDRIVVRRSAKTINLLHPVGYNYYATLRKK
ECCCEEEEEEECCCEEEECCCHHHHHHHCCCCEEEEEECCCEEEEECCCCCCHHHHHHHH
LHWHEYPTEDNRL
HHCCCCCCCCCCC
>Mature Secondary Structure 
PVWSNPGMSAPHKTGAARPPFKTVALVGRHSTAGIEGPLEELASCISRNGQDVVFERET
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCH
AMATGLTGYPVLTPDEIGREADVAVVLGGDGTLLGLARQLAGHDVPVIGVNHGRLGFMTD
HHHCCCCCCCEECHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEC
IPLDAISTALPEMLSGRYEAETRMLLESRVIRDDSVIFSALAFNDVVVNRSGISGMVELA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHEEHHHHHCEEEEECCCCCCEEEEE
VSVDGYFMYNQRSDGLIVSTPTGSTAYALAAGGPILHPTLSGLVLVPIAPHALSNRPIVL
EEECEEEEEECCCCCEEEECCCCCCEEEEECCCCEECCCCCCEEEEEECCHHCCCCCEEE
PYDAEVTIEVASARDVSVNFDMQALASLLPGDRIVVRRSAKTINLLHPVGYNYYATLRKK
ECCCEEEEEEECCCEEEECCCHHHHHHHCCCCEEEEEECCCEEEEECCCCCCHHHHHHHH
LHWHEYPTEDNRL
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA