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The map label for this gene is nuoN [H]

Identifier: 94309885

GI number: 94309885

Start: 1026083

End: 1027558

Strand: Direct

Name: nuoN [H]

Synonym: Rmet_0940

Alternate gene names: 94309885

Gene position: 1026083-1027558 (Clockwise)

Preceding gene: 94309884

Following gene: 94309886

Centisome position: 26.12

GC content: 62.06

Gene sequence:

>1476_bases
ATGCAATCGTCCTCTAGCCTGGCCCCGGTGGCGCCAATCATTTTCCTGGCGATCGCCATTGCGGCGATCAACTGGATCGA
CCTAGCCCGCGGCAAGAACCGCACCAGCGTGGCGTACCCGCTGTCGCTGCTGACTACACTGGTGCTGACCGCTTGGTTCG
GCATCGACGCGGCAGGCGGCGAAACGCACTACGCGTTCGCCAACCTGGTCGTGATCGACCCGATGGCGAACGTGCTGGCT
GCGTTCTGCTCGCTGGGTATGCTGCTGACGCTGATCTACACGCGTAGCTATCTGGCCGAACGGGACATGTTCGCAGGCGA
GTTCTACATGCTCGCGCTGTTCACGCTCGGCGGTCAGATCGTGATGATCACCGGCAACAACTTCCTGACGCTGTACCTGG
GTCTGGAGCTGCTGTCTCTGTCGTCGTATGCGCTGGTTGCCCTGCGCCGCGACTCGCGCGTGACGTCCGAATCGGCGATC
AAGTACTTTGTACTGGGCGCGCTCGCATCGGGCTTCCTGCTCTACGGCATGTCGATGATGTACGGGGCCACCGGTTCGCT
GAACCTGGGTGAAGTGTTCCGCGTGGTCGAGTCGGGCCGCGTCAACACGACGATGCTGGCCTTCGGCGTGGTGTTTATCG
TGGCCGGTGTGGCCTTCAAGCTGGGTGCCGCACCGTTCCATATGTGGATCCCGGACATCTACCAGGGTTCGCCGACCGCT
GTGACGCTGCTGATCGCTGCTGGTCCGAAGGTTGCCGCATTCGCGCTGATCATCCGCCTGCTGGTGGAGGGCCTGCTGCC
GCTGGCGACCGACTGGCAGGTCATGCTGGTGATCCTGTCGATTGCTTCGCTGGTCATCGGTAACCTGACGGCTATCGTTC
AGACAAACCTGAAGCGGATGCTGGCGTACTCGACGATCTCCCACATGGGCTTCGTGCTGCTGGGCATGCTTTCGGGCGTG
GTGGCCAACAAGGCCGACGGCGCAGTGAACGCCTACAGCTCGTCGATGTTCTACTCGATCACGTACATGCTGACCACGCT
GGGCACGTTCGGCCTGATCCTGGTTCGCACGCGCAAGGGCTTCGAGGCAGAAACGCTCGACGATCTGAAGGGCATGTCGC
GCCGTCATCCGTGGTTCGCGTTCCTGATGCTGGTGATGATGTTCTCGATGGCCGGCATTCCGCCGACCGTTGGCTTCTAT
GCCAAGCTGTCGGTGCTGCAGGCGGTCGTGTCGGCAGGTATGAGCTGGCTGGCCGTGCTGGCAGTGGTGTTCTCGCTGAT
CGGCGCGTTCTACTACCTGCGCATTGTGAAGCTGATGTACTTCGATGCACCGGTTGGCGAAGAGCCGCTGGAAGCTTCGA
CTGGCCTGCGTTCGGTGCTGAGCCTGAACGGCTTGGCCGTGATCCTGCTGGGTCTGTTCCCGGCTGGCCTGATGGACCTG
TGCTTCCAGGCCATCCGTGCTACGCTGGCGTCCTGA

Upstream 100 bases:

>100_bases
CTGTACCCGAAACCCTTCACCGACGTGATGCACGCATCGGTGGTGAACCTGCTGTCCCACGTGGCACAGTCCAAGCTGTA
AGCGGGGGAGAGAAATCAAC

Downstream 100 bases:

>100_bases
TTTTTCAGGCAAGGTGACGCAATGAGTTCCTCGGCAGGTGGTTGGTTTGTCATCCTTTTGGCACTGGTGTGTGCCAACCT
GCCGTTCGTCAACCAGCGCC

Product: NADH:ubiquinone oxidoreductase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MQSSSSLAPVAPIIFLAIAIAAINWIDLARGKNRTSVAYPLSLLTTLVLTAWFGIDAAGGETHYAFANLVVIDPMANVLA
AFCSLGMLLTLIYTRSYLAERDMFAGEFYMLALFTLGGQIVMITGNNFLTLYLGLELLSLSSYALVALRRDSRVTSESAI
KYFVLGALASGFLLYGMSMMYGATGSLNLGEVFRVVESGRVNTTMLAFGVVFIVAGVAFKLGAAPFHMWIPDIYQGSPTA
VTLLIAAGPKVAAFALIIRLLVEGLLPLATDWQVMLVILSIASLVIGNLTAIVQTNLKRMLAYSTISHMGFVLLGMLSGV
VANKADGAVNAYSSSMFYSITYMLTTLGTFGLILVRTRKGFEAETLDDLKGMSRRHPWFAFLMLVMMFSMAGIPPTVGFY
AKLSVLQAVVSAGMSWLAVLAVVFSLIGAFYYLRIVKLMYFDAPVGEEPLEASTGLRSVLSLNGLAVILLGLFPAGLMDL
CFQAIRATLAS

Sequences:

>Translated_491_residues
MQSSSSLAPVAPIIFLAIAIAAINWIDLARGKNRTSVAYPLSLLTTLVLTAWFGIDAAGGETHYAFANLVVIDPMANVLA
AFCSLGMLLTLIYTRSYLAERDMFAGEFYMLALFTLGGQIVMITGNNFLTLYLGLELLSLSSYALVALRRDSRVTSESAI
KYFVLGALASGFLLYGMSMMYGATGSLNLGEVFRVVESGRVNTTMLAFGVVFIVAGVAFKLGAAPFHMWIPDIYQGSPTA
VTLLIAAGPKVAAFALIIRLLVEGLLPLATDWQVMLVILSIASLVIGNLTAIVQTNLKRMLAYSTISHMGFVLLGMLSGV
VANKADGAVNAYSSSMFYSITYMLTTLGTFGLILVRTRKGFEAETLDDLKGMSRRHPWFAFLMLVMMFSMAGIPPTVGFY
AKLSVLQAVVSAGMSWLAVLAVVFSLIGAFYYLRIVKLMYFDAPVGEEPLEASTGLRSVLSLNGLAVILLGLFPAGLMDL
CFQAIRATLAS
>Mature_491_residues
MQSSSSLAPVAPIIFLAIAIAAINWIDLARGKNRTSVAYPLSLLTTLVLTAWFGIDAAGGETHYAFANLVVIDPMANVLA
AFCSLGMLLTLIYTRSYLAERDMFAGEFYMLALFTLGGQIVMITGNNFLTLYLGLELLSLSSYALVALRRDSRVTSESAI
KYFVLGALASGFLLYGMSMMYGATGSLNLGEVFRVVESGRVNTTMLAFGVVFIVAGVAFKLGAAPFHMWIPDIYQGSPTA
VTLLIAAGPKVAAFALIIRLLVEGLLPLATDWQVMLVILSIASLVIGNLTAIVQTNLKRMLAYSTISHMGFVLLGMLSGV
VANKADGAVNAYSSSMFYSITYMLTTLGTFGLILVRTRKGFEAETLDDLKGMSRRHPWFAFLMLVMMFSMAGIPPTVGFY
AKLSVLQAVVSAGMSWLAVLAVVFSLIGAFYYLRIVKLMYFDAPVGEEPLEASTGLRSVLSLNGLAVILLGLFPAGLMDL
CFQAIRATLAS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=201, Percent_Identity=29.3532338308458, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI145693160, Length=422, Percent_Identity=34.1232227488152, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1788614, Length=428, Percent_Identity=24.5327102803738, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788831, Length=384, Percent_Identity=25.5208333333333, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788827, Length=345, Percent_Identity=25.7971014492754, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788613, Length=352, Percent_Identity=25.5681818181818, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI2367154, Length=266, Percent_Identity=24.0601503759398, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52759; Mature: 52759

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSSSSLAPVAPIIFLAIAIAAINWIDLARGKNRTSVAYPLSLLTTLVLTAWFGIDAAGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
ETHYAFANLVVIDPMANVLAAFCSLGMLLTLIYTRSYLAERDMFAGEFYMLALFTLGGQI
CCCHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEE
VMITGNNFLTLYLGLELLSLSSYALVALRRDSRVTSESAIKYFVLGALASGFLLYGMSMM
EEEECCCEEEEHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGATGSLNLGEVFRVVESGRVNTTMLAFGVVFIVAGVAFKLGAAPFHMWIPDIYQGSPTA
HCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCE
VTLLIAAGPKVAAFALIIRLLVEGLLPLATDWQVMLVILSIASLVIGNLTAIVQTNLKRM
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYSTISHMGFVLLGMLSGVVANKADGAVNAYSSSMFYSITYMLTTLGTFGLILVRTRKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
FEAETLDDLKGMSRRHPWFAFLMLVMMFSMAGIPPTVGFYAKLSVLQAVVSAGMSWLAVL
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
AVVFSLIGAFYYLRIVKLMYFDAPVGEEPLEASTGLRSVLSLNGLAVILLGLFPAGLMDL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
CFQAIRATLAS
HHHHHHHHHCC
>Mature Secondary Structure
MQSSSSLAPVAPIIFLAIAIAAINWIDLARGKNRTSVAYPLSLLTTLVLTAWFGIDAAGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
ETHYAFANLVVIDPMANVLAAFCSLGMLLTLIYTRSYLAERDMFAGEFYMLALFTLGGQI
CCCHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEE
VMITGNNFLTLYLGLELLSLSSYALVALRRDSRVTSESAIKYFVLGALASGFLLYGMSMM
EEEECCCEEEEHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGATGSLNLGEVFRVVESGRVNTTMLAFGVVFIVAGVAFKLGAAPFHMWIPDIYQGSPTA
HCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCE
VTLLIAAGPKVAAFALIIRLLVEGLLPLATDWQVMLVILSIASLVIGNLTAIVQTNLKRM
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYSTISHMGFVLLGMLSGVVANKADGAVNAYSSSMFYSITYMLTTLGTFGLILVRTRKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
FEAETLDDLKGMSRRHPWFAFLMLVMMFSMAGIPPTVGFYAKLSVLQAVVSAGMSWLAVL
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
AVVFSLIGAFYYLRIVKLMYFDAPVGEEPLEASTGLRSVLSLNGLAVILLGLFPAGLMDL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
CFQAIRATLAS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA