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The map label for this gene is cbbJ2 [H]

Identifier: 94309870

GI number: 94309870

Start: 1010940

End: 1011677

Strand: Direct

Name: cbbJ2 [H]

Synonym: Rmet_0925

Alternate gene names: 94309870

Gene position: 1010940-1011677 (Clockwise)

Preceding gene: 94309869

Following gene: 94309871

Centisome position: 25.74

GC content: 61.92

Gene sequence:

>738_bases
GTGAGACAAAAGCTGGTCATCGGCAATTGGAAGATGCATGGCAGCCTGGCCGCCAACGCGGCGCTGCTTGAGGGTATCAA
GGCTGCGCCTGCGCGCGCGAAGCTGGCGGTCTGCGCGCCGTTCCCCTATCTTGCCCAGTGCCAGACGCTGTTGTCCGGTT
CCCAGGTTGCCTGGGGTGCTCAGGATGTGTCGTCCGAGGCCCGTGGTGCCTTCACCGGTGAAGTAGCTGCCTCGATGCTG
GGTGAGTTTGGTTGCGGCTATGCGCTCGTCGGCCATTCAGAGCGTCGTACCTACCATGGTGAAACCGACGCGGTAGTGGC
TGCCAAGGCACTGCGCGCGCTGGAATTCGACATTGTTCCGGTGGTCTGTGTTGGAGAGACGCTGGCCGAGCGCGAAGCCG
GTCAGACCGAAGCCGTGGTTGGTCGTCAGTTGCAGGCTGTACTCGATGCGTTGTCTATCGAGCAACTGGGTCGCATTGTT
CTGGCCTATGAGCCCGTCTGGGCGATCGGTACGGGCAAGACGGCCACGAGCGCGCAGGCCCAGGAAGTTCATGCGGCGCT
ACGTGCGCGGGTCACGGCGAAGGATGCCGGTGTTGCAGCACGCATGGCCATTCTGTATGGCGGTAGCGTCAAGCCCGACA
ATGCAGCTGAATTGTTTTCCATGTCCGATATTGACGGGGGGCTTATTGGTGGCGCCTCCCTGAAGGCGGATGATTTCCTC
GCGATCGGCAACGCCTGA

Upstream 100 bases:

>100_bases
TCACTGGCGGGTCCGGGATTACCTGCGATTGCCCGCACATGCTGGCGGGCCCCTCCTGACCACGCTACAATAGCCGGTTT
GATTTAAAGAGGGGACCCTT

Downstream 100 bases:

>100_bases
ATGCCGGACGCGACTGTCTGATCAGGCAAGTTCGAAACGACTTTAACCAAATGGCAATCTTCAAGACTTTGTTGGTAATC
GTGCAGGTCCTGTCCGCGCT

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRQKLVIGNWKMHGSLAANAALLEGIKAAPARAKLAVCAPFPYLAQCQTLLSGSQVAWGAQDVSSEARGAFTGEVAASML
GEFGCGYALVGHSERRTYHGETDAVVAAKALRALEFDIVPVVCVGETLAEREAGQTEAVVGRQLQAVLDALSIEQLGRIV
LAYEPVWAIGTGKTATSAQAQEVHAALRARVTAKDAGVAARMAILYGGSVKPDNAAELFSMSDIDGGLIGGASLKADDFL
AIGNA

Sequences:

>Translated_245_residues
MRQKLVIGNWKMHGSLAANAALLEGIKAAPARAKLAVCAPFPYLAQCQTLLSGSQVAWGAQDVSSEARGAFTGEVAASML
GEFGCGYALVGHSERRTYHGETDAVVAAKALRALEFDIVPVVCVGETLAEREAGQTEAVVGRQLQAVLDALSIEQLGRIV
LAYEPVWAIGTGKTATSAQAQEVHAALRARVTAKDAGVAARMAILYGGSVKPDNAAELFSMSDIDGGLIGGASLKADDFL
AIGNA
>Mature_245_residues
MRQKLVIGNWKMHGSLAANAALLEGIKAAPARAKLAVCAPFPYLAQCQTLLSGSQVAWGAQDVSSEARGAFTGEVAASML
GEFGCGYALVGHSERRTYHGETDAVVAAKALRALEFDIVPVVCVGETLAEREAGQTEAVVGRQLQAVLDALSIEQLGRIV
LAYEPVWAIGTGKTATSAQAQEVHAALRARVTAKDAGVAARMAILYGGSVKPDNAAELFSMSDIDGGLIGGASLKADDFL
AIGNA

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=248, Percent_Identity=42.741935483871, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI226529917, Length=248, Percent_Identity=42.741935483871, Blast_Score=172, Evalue=2e-43,
Organism=Escherichia coli, GI1790353, Length=245, Percent_Identity=48.1632653061224, Blast_Score=221, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17536593, Length=249, Percent_Identity=48.5943775100402, Blast_Score=199, Evalue=9e-52,
Organism=Saccharomyces cerevisiae, GI6320255, Length=247, Percent_Identity=40.8906882591093, Blast_Score=176, Evalue=3e-45,
Organism=Drosophila melanogaster, GI28572004, Length=247, Percent_Identity=44.5344129554656, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28572008, Length=247, Percent_Identity=44.5344129554656, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28572006, Length=247, Percent_Identity=44.5344129554656, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25353; Mature: 25353

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQKLVIGNWKMHGSLAANAALLEGIKAAPARAKLAVCAPFPYLAQCQTLLSGSQVAWGA
CCCCEEEECEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCEECCH
QDVSSEARGAFTGEVAASMLGEFGCGYALVGHSERRTYHGETDAVVAAKALRALEFDIVP
HHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
VVCVGETLAEREAGQTEAVVGRQLQAVLDALSIEQLGRIVLAYEPVWAIGTGKTATSAQA
EEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCHHH
QEVHAALRARVTAKDAGVAARMAILYGGSVKPDNAAELFSMSDIDGGLIGGASLKADDFL
HHHHHHHHHHHHHCCCCHHHEEHEEECCCCCCCCHHHHEECCCCCCCEECCCCCCCCCEE
AIGNA
EECCC
>Mature Secondary Structure
MRQKLVIGNWKMHGSLAANAALLEGIKAAPARAKLAVCAPFPYLAQCQTLLSGSQVAWGA
CCCCEEEECEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCEECCH
QDVSSEARGAFTGEVAASMLGEFGCGYALVGHSERRTYHGETDAVVAAKALRALEFDIVP
HHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEE
VVCVGETLAEREAGQTEAVVGRQLQAVLDALSIEQLGRIVLAYEPVWAIGTGKTATSAQA
EEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCHHH
QEVHAALRARVTAKDAGVAARMAILYGGSVKPDNAAELFSMSDIDGGLIGGASLKADDFL
HHHHHHHHHHHHHCCCCHHHEEHEEECCCCCCCCHHHHEECCCCCCCEECCCCCCCCCEE
AIGNA
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA