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The map label for this gene is qorA [H]

Identifier: 94309869

GI number: 94309869

Start: 1009808

End: 1010812

Strand: Direct

Name: qorA [H]

Synonym: Rmet_0924

Alternate gene names: 94309869

Gene position: 1009808-1010812 (Clockwise)

Preceding gene: 94309868

Following gene: 94309870

Centisome position: 25.71

GC content: 63.28

Gene sequence:

>1005_bases
ATGAAAGCCATCGAGATCCGTGAATACGGCGCCCCCGAAGTCCTGCAGGAAACGCAGCGTCCCGATCCGGAGCCGAAGGC
CGGTGAAATCCTGATTCGTGTGGCGGCTGCTGGCATCAACCGTCCCGATGTGTTCCAGCGCACCGGCAACTATCCGGTGC
CGCCCGGTGCGTCGGATCTTCCTGGTCTCGAGGTCGCAGGTGTGGTCGTTGGGGGAGACCTTTCGCATCCCGCCAATCGC
TTCGGCCTGAAAGCTGGCGACCGTGTCTGCGCGTTGGTGCAGGGCGGTGGTTACGCCGAGCTGTGCACGGCGCCGATCGA
GCAATGCCTGCCGGTACCCGAGGGCCTCACCGATATCGAAGCGGCTGCGCTACCCGAGACGTTCTTCACGGTGTGGAGCA
ACGTGTTCGATCGTGGTCAGCTTGGCAAGGGTCCGCGTGGCGCGGCCGAAACGCTGCTGATCCAGGGTGGGTCTAGCGGC
ATCGGTACCACGGCAATCCAGATCGCCAAGGCACTTGGCTTCAAGGTCTTCGTGACGGCCGGCAGCGATGACAAGTGCAA
GGCGTGCGAGTCGCTCGGCGCGGATCGCGCGATCAACTACAAGACGCAGGATTTCGTGGCCGAAGTGAAGGCGCTGACCG
AAGGGAAGGGCGTCGACGTGATCCTCGATATGGTGGCGGGGTCCTATCTCGCGCGTGAACTGTCGTGCATCGCCGATGAC
GGCCGCATCGTGATCATCGCGCTGCTTGGTGGCGGCAAGGCGGAAATTCCCCTTGGCGACATCCTGCGTCGACGCATTAC
CATCACCGGTTCCACGCTGCGCCCGCGTCCGGCTTCATTCAAGGGCGCCATTGCGCAGGCGCTGCATCAGAACGTCTGGC
CGCTGCTGGCATCGGGCAAGATCAAGCCCGTGATCCACAAGGTGTTCCCCGCAGCACAGGCCGCGGATGCGCATCGCCTG
ATGGAGTCGAGCGAGCATATCGGCAAGATCGTACTGACCTGGTAA

Upstream 100 bases:

>100_bases
TTTACACTGCCGGTCAGTTCGCTATCCGGTTCGCCTGCGACACGTGCGTCAGCAACGCCATCGCGCGCGATGCAATCCAA
GACATTAATGAGGAGTCATC

Downstream 100 bases:

>100_bases
GCCATGCTTCTTGCTGTGGGCCCGTGATCACTGGCGGGTCCGGGATTACCTGCGATTGCCCGCACATGCTGGCGGGCCCC
TCCTGACCACGCTACAATAG

Product: Zinc-binding dehydrogenase superfamiy protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKAIEIREYGAPEVLQETQRPDPEPKAGEILIRVAAAGINRPDVFQRTGNYPVPPGASDLPGLEVAGVVVGGDLSHPANR
FGLKAGDRVCALVQGGGYAELCTAPIEQCLPVPEGLTDIEAAALPETFFTVWSNVFDRGQLGKGPRGAAETLLIQGGSSG
IGTTAIQIAKALGFKVFVTAGSDDKCKACESLGADRAINYKTQDFVAEVKALTEGKGVDVILDMVAGSYLARELSCIADD
GRIVIIALLGGGKAEIPLGDILRRRITITGSTLRPRPASFKGAIAQALHQNVWPLLASGKIKPVIHKVFPAAQAADAHRL
MESSEHIGKIVLTW

Sequences:

>Translated_334_residues
MKAIEIREYGAPEVLQETQRPDPEPKAGEILIRVAAAGINRPDVFQRTGNYPVPPGASDLPGLEVAGVVVGGDLSHPANR
FGLKAGDRVCALVQGGGYAELCTAPIEQCLPVPEGLTDIEAAALPETFFTVWSNVFDRGQLGKGPRGAAETLLIQGGSSG
IGTTAIQIAKALGFKVFVTAGSDDKCKACESLGADRAINYKTQDFVAEVKALTEGKGVDVILDMVAGSYLARELSCIADD
GRIVIIALLGGGKAEIPLGDILRRRITITGSTLRPRPASFKGAIAQALHQNVWPLLASGKIKPVIHKVFPAAQAADAHRL
MESSEHIGKIVLTW
>Mature_334_residues
MKAIEIREYGAPEVLQETQRPDPEPKAGEILIRVAAAGINRPDVFQRTGNYPVPPGASDLPGLEVAGVVVGGDLSHPANR
FGLKAGDRVCALVQGGGYAELCTAPIEQCLPVPEGLTDIEAAALPETFFTVWSNVFDRGQLGKGPRGAAETLLIQGGSSG
IGTTAIQIAKALGFKVFVTAGSDDKCKACESLGADRAINYKTQDFVAEVKALTEGKGVDVILDMVAGSYLARELSCIADD
GRIVIIALLGGGKAEIPLGDILRRRITITGSTLRPRPASFKGAIAQALHQNVWPLLASGKIKPVIHKVFPAAQAADAHRL
MESSEHIGKIVLTW

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=38.0952380952381, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=38.0952380952381, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI194239674, Length=338, Percent_Identity=31.9526627218935, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI13236495, Length=338, Percent_Identity=31.9526627218935, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI18379349, Length=321, Percent_Identity=30.8411214953271, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI194239676, Length=338, Percent_Identity=29.585798816568, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=25.3561253561254, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41872631, Length=257, Percent_Identity=33.0739299610895, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI47519420, Length=360, Percent_Identity=29.4444444444444, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI197927207, Length=186, Percent_Identity=30.6451612903226, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI28557745, Length=282, Percent_Identity=27.3049645390071, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1790485, Length=339, Percent_Identity=31.5634218289086, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI226510941, Length=279, Percent_Identity=26.5232974910394, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=335, Percent_Identity=26.5671641791045, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=326, Percent_Identity=27.6073619631902, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=346, Percent_Identity=26.0115606936416, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=287, Percent_Identity=26.4808362369338, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=343, Percent_Identity=23.9067055393586, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=347, Percent_Identity=23.342939481268, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221330659, Length=282, Percent_Identity=29.7872340425532, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19920632, Length=282, Percent_Identity=29.7872340425532, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24581345, Length=282, Percent_Identity=29.0780141843972, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35159; Mature: 35159

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEIREYGAPEVLQETQRPDPEPKAGEILIRVAAAGINRPDVFQRTGNYPVPPGASDL
CCCEECCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGVVVGGDLSHPANRFGLKAGDRVCALVQGGGYAELCTAPIEQCLPVPEGLTDIE
CCCEEEEEEEECCCCCCHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
AAALPETFFTVWSNVFDRGQLGKGPRGAAETLLIQGGSSGIGTTAIQIAKALGFKVFVTA
HHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEC
GSDDKCKACESLGADRAINYKTQDFVAEVKALTEGKGVDVILDMVAGSYLARELSCIADD
CCCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECC
GRIVIIALLGGGKAEIPLGDILRRRITITGSTLRPRPASFKGAIAQALHQNVWPLLASGK
CCEEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHCCCC
IKPVIHKVFPAAQAADAHRLMESSEHIGKIVLTW
CHHHHHHHHCCHHHHHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure
MKAIEIREYGAPEVLQETQRPDPEPKAGEILIRVAAAGINRPDVFQRTGNYPVPPGASDL
CCCEECCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGVVVGGDLSHPANRFGLKAGDRVCALVQGGGYAELCTAPIEQCLPVPEGLTDIE
CCCEEEEEEEECCCCCCHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
AAALPETFFTVWSNVFDRGQLGKGPRGAAETLLIQGGSSGIGTTAIQIAKALGFKVFVTA
HHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEC
GSDDKCKACESLGADRAINYKTQDFVAEVKALTEGKGVDVILDMVAGSYLARELSCIADD
CCCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECC
GRIVIIALLGGGKAEIPLGDILRRRITITGSTLRPRPASFKGAIAQALHQNVWPLLASGK
CCEEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHCCCC
IKPVIHKVFPAAQAADAHRLMESSEHIGKIVLTW
CHHHHHHHHCCHHHHHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]