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The map label for this gene is yngJ [H]

Identifier: 94309790

GI number: 94309790

Start: 925373

End: 926569

Strand: Direct

Name: yngJ [H]

Synonym: Rmet_0845

Alternate gene names: 94309790

Gene position: 925373-926569 (Clockwise)

Preceding gene: 94309789

Following gene: 94309791

Centisome position: 23.56

GC content: 64.08

Gene sequence:

>1197_bases
ATGGATCTGCTGTTGACACCCGAACTTGTCGAGTTTCGGGACACCGTACGCGCTTTCCTGCGCGAGCATCTGCCTGCGGA
ACTGCGTCGGGGGCAGCAACTCACGACGGCGATGTATCCGGAGCCGGAAATCTCGGGCCCGTGGCAGGCACGTCTGCGTG
AGCGTGGATGGCTCGTCCCACTGTGGCCCAGGGAGTGGGGCGGCACGGGATGGAGCAGTATCGAACGATTCATCTTCGAA
ACGGAATGCGCACTCGCTGGCGCGCCGCTTGTCCATCCGATGGGGGTGAGGCTGGTCGGGCCGGTGATACTGCGATACGG
CACCGAGGCGCAAAAGCAGACATATCTGTCGCGCATCCTTTCCGGGCAGGACTACTGGTGCCAGGGATTCTCGGAGCCCG
GCGCCGGTTCTGATCTGGCATCGCTGCGAACCCGTGCCGTACGCGATGGTGACCACTACGTCATCAACGGCAGCAAGTTG
TGGACGACCCACGCCCACCACGCGAATCGCATGTTCGCACTCGTGCGCACCAGCACCGAAGGGCGGCGGCAGGAGGGCAT
CAGCTTCATTCTTATCGACATGGAAACGCCCGGGATCTCGGTTCGCCCGATTCCAACCATAGGTGGCGACCATGACGTCA
ACGAAGTGTTCTTCGACAACGTGCGCGTGCCCGTCGCCAACCGCATCGGCGCGGAGAACGAAGGCTGGCAGTGCGCGCGC
TATCTGCTGGAGTTCGAGCGCGGGGCCGGCATCTTCAGTCCTCGCCTGCGCTCGCAACTCAAGCGGATCGGCGACGTGCT
GGCGAGAGAGGCACAGTGTGATGGCGATACCACTGTCACTGCCTTGCGGCGGCTCCGGTTCGGAGAGGTGCGCGCCGATC
TCGACGCCTTCGAGATGCTCGAATTGAAGACGATGTGTTCGGTGGCGCCGGGTGAGAGCCCCGGTCCGGTGGCGTCGGTC
CTGAAGCTCCGCGCCAGCAGGCTGCGGCAGGCAATCAGCGAAATGGGGACGACGGTTGTTGGCGCCGAGAGCTTGCGATG
GCGCGCGGACGACGCCCACGATGAGGAGCCTTCCGAAGACGAGGTGTTGCGCGCGTGTTTGCTGCCTGACTTCCTCAATG
CGCGGGCCTACACGATCTTCGGCGGTGCGGCCGAGGTCCAGTTGGGCATTATCGCGAAGTCCTGCCTGGGGGCCTGA

Upstream 100 bases:

>100_bases
TGGGGAATGACATGTACACCGGCGACTGGCGCATGAGCCAGACCTTGCTTGATCCGGCGACATCTGGCCAGGCTGTGGCG
GCATATGCGGAGGCACACTG

Downstream 100 bases:

>100_bases
TTCGGTGGAGCCGCCCGGGAGGCGGGCATATGCCGAGGGCAGTCCGACCGTCCGACTGTTTGCGAACGGAGGAATCTGGC
GGAAGCGGTGTCCGTCGAGC

Product: Acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDLLLTPELVEFRDTVRAFLREHLPAELRRGQQLTTAMYPEPEISGPWQARLRERGWLVPLWPREWGGTGWSSIERFIFE
TECALAGAPLVHPMGVRLVGPVILRYGTEAQKQTYLSRILSGQDYWCQGFSEPGAGSDLASLRTRAVRDGDHYVINGSKL
WTTHAHHANRMFALVRTSTEGRRQEGISFILIDMETPGISVRPIPTIGGDHDVNEVFFDNVRVPVANRIGAENEGWQCAR
YLLEFERGAGIFSPRLRSQLKRIGDVLAREAQCDGDTTVTALRRLRFGEVRADLDAFEMLELKTMCSVAPGESPGPVASV
LKLRASRLRQAISEMGTTVVGAESLRWRADDAHDEEPSEDEVLRACLLPDFLNARAYTIFGGAAEVQLGIIAKSCLGA

Sequences:

>Translated_398_residues
MDLLLTPELVEFRDTVRAFLREHLPAELRRGQQLTTAMYPEPEISGPWQARLRERGWLVPLWPREWGGTGWSSIERFIFE
TECALAGAPLVHPMGVRLVGPVILRYGTEAQKQTYLSRILSGQDYWCQGFSEPGAGSDLASLRTRAVRDGDHYVINGSKL
WTTHAHHANRMFALVRTSTEGRRQEGISFILIDMETPGISVRPIPTIGGDHDVNEVFFDNVRVPVANRIGAENEGWQCAR
YLLEFERGAGIFSPRLRSQLKRIGDVLAREAQCDGDTTVTALRRLRFGEVRADLDAFEMLELKTMCSVAPGESPGPVASV
LKLRASRLRQAISEMGTTVVGAESLRWRADDAHDEEPSEDEVLRACLLPDFLNARAYTIFGGAAEVQLGIIAKSCLGA
>Mature_398_residues
MDLLLTPELVEFRDTVRAFLREHLPAELRRGQQLTTAMYPEPEISGPWQARLRERGWLVPLWPREWGGTGWSSIERFIFE
TECALAGAPLVHPMGVRLVGPVILRYGTEAQKQTYLSRILSGQDYWCQGFSEPGAGSDLASLRTRAVRDGDHYVINGSKL
WTTHAHHANRMFALVRTSTEGRRQEGISFILIDMETPGISVRPIPTIGGDHDVNEVFFDNVRVPVANRIGAENEGWQCAR
YLLEFERGAGIFSPRLRSQLKRIGDVLAREAQCDGDTTVTALRRLRFGEVRADLDAFEMLELKTMCSVAPGESPGPVASV
LKLRASRLRQAISEMGTTVVGAESLRWRADDAHDEEPSEDEVLRACLLPDFLNARAYTIFGGAAEVQLGIIAKSCLGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=251, Percent_Identity=28.2868525896414, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4501859, Length=409, Percent_Identity=26.6503667481663, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI187960098, Length=412, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557231, Length=412, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226958414, Length=205, Percent_Identity=29.2682926829268, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI21361497, Length=245, Percent_Identity=27.7551020408163, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7656849, Length=177, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557233, Length=346, Percent_Identity=29.1907514450867, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4557235, Length=216, Percent_Identity=32.4074074074074, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI76496475, Length=216, Percent_Identity=32.4074074074074, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI48976061, Length=314, Percent_Identity=28.0254777070064, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI211971008, Length=314, Percent_Identity=28.0254777070064, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38505218, Length=262, Percent_Identity=28.2442748091603, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4501857, Length=306, Percent_Identity=25.1633986928105, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI87081958, Length=249, Percent_Identity=26.5060240963855, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786223, Length=212, Percent_Identity=25.9433962264151, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=421, Percent_Identity=25.1781472684086, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=409, Percent_Identity=26.161369193154, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=208, Percent_Identity=31.25, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=205, Percent_Identity=31.219512195122, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=373, Percent_Identity=26.2734584450402, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=359, Percent_Identity=27.0194986072423, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=152, Percent_Identity=34.8684210526316, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=149, Percent_Identity=34.8993288590604, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=182, Percent_Identity=33.5164835164835, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=353, Percent_Identity=24.0793201133144, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=353, Percent_Identity=25.2124645892351, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562446, Length=380, Percent_Identity=25.5263157894737, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=288, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=194, Percent_Identity=26.8041237113402, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355753, Length=206, Percent_Identity=32.5242718446602, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281363737, Length=244, Percent_Identity=29.5081967213115, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356377, Length=243, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24666513, Length=250, Percent_Identity=30.4, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24660351, Length=412, Percent_Identity=24.7572815533981, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646207, Length=241, Percent_Identity=28.6307053941909, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 44300; Mature: 44300

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLTPELVEFRDTVRAFLREHLPAELRRGQQLTTAMYPEPEISGPWQARLRERGWLVP
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCCCCHHHHHHHCCCEEE
LWPREWGGTGWSSIERFIFETECALAGAPLVHPMGVRLVGPVILRYGTEAQKQTYLSRIL
CCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
SGQDYWCQGFSEPGAGSDLASLRTRAVRDGDHYVINGSKLWTTHAHHANRMFALVRTSTE
CCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHEEEEEECCCC
GRRQEGISFILIDMETPGISVRPIPTIGGDHDVNEVFFDNVRVPVANRIGAENEGWQCAR
CHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHHHCCCCCCHHHHCCCCCCCHHHHH
YLLEFERGAGIFSPRLRSQLKRIGDVLAREAQCDGDTTVTALRRLRFGEVRADLDAFEML
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHH
ELKTMCSVAPGESPGPVASVLKLRASRLRQAISEMGTTVVGAESLRWRADDAHDEEPSED
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHEECCCCCCCCCCCHH
EVLRACLLPDFLNARAYTIFGGAAEVQLGIIAKSCLGA
HHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLLLTPELVEFRDTVRAFLREHLPAELRRGQQLTTAMYPEPEISGPWQARLRERGWLVP
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCCCCHHHHHHHCCCEEE
LWPREWGGTGWSSIERFIFETECALAGAPLVHPMGVRLVGPVILRYGTEAQKQTYLSRIL
CCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
SGQDYWCQGFSEPGAGSDLASLRTRAVRDGDHYVINGSKLWTTHAHHANRMFALVRTSTE
CCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHEEEEEECCCC
GRRQEGISFILIDMETPGISVRPIPTIGGDHDVNEVFFDNVRVPVANRIGAENEGWQCAR
CHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHHHCCCCCCHHHHCCCCCCCHHHHH
YLLEFERGAGIFSPRLRSQLKRIGDVLAREAQCDGDTTVTALRRLRFGEVRADLDAFEML
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHH
ELKTMCSVAPGESPGPVASVLKLRASRLRQAISEMGTTVVGAESLRWRADDAHDEEPSED
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHEECCCCCCCCCCCHH
EVLRACLLPDFLNARAYTIFGGAAEVQLGIIAKSCLGA
HHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]