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The map label for this gene is glnS [H]

Identifier: 94309763

GI number: 94309763

Start: 889587

End: 891335

Strand: Reverse

Name: glnS [H]

Synonym: Rmet_0818

Alternate gene names: 94309763

Gene position: 891335-889587 (Counterclockwise)

Preceding gene: 94309765

Following gene: 94309762

Centisome position: 22.69

GC content: 64.04

Gene sequence:

>1749_bases
ATGAGCCACGACACCAAACCCAACGACACGCCCGCCGCCTCCAACTTCCTGCGGAGCATCATCGACCAGGACCTCGCCAC
CGGCACCTACGCCGGCCGCGCGGACAAGCAAGGCGACCCGCTGCCGACAGTCATCACGCGCTTCCCGCCGGAGCCGAACG
GCTACCTGCACATTGGTCACGCCAAGAGCATCTGCGTGAACTTCGGGCTGGCCCGCGACTATGCCGGCCGCTGCCATCTG
CGCTTCGATGACACGAACCCGGTGAAGGAAGACACCGAGTACGTCGACTCGATCATCGATGCCGTGCACTGGCTCGGCTT
CTCCTGGGATAGCGCCCAGGCGGGCAGCACGCCGCACCTGTACTTCGCGAGCGACTACTTCGACCAGCTCTACAAGTTTG
CCGAGACGCTGATCGAGCGCGGCGTGGCCTATGTGGACAGCCAGAGCGCCGAGCAGATCGCCGCCATGCGCGGCAACTTT
TCCGAGCCGGGCAAGCCGTCGCCGTTCCGCGACCGCTCGGTCGAGGAGAACCTGAAGCTGTTCCGCGAGATGCGCGACGG
CAAGTACGCCGACGGCGAGCACGTGCTGCGCGCGAAGATCGACATGACCGCCCCGAACATCGTGATGCGCGATCCGGTGC
TCTACCGCATCCGCCACGCCCATCACCACCGTACCGGCGACAAGTGGTGCATCTACCCGATGTACGACTTCACGCATTGC
ATCTCGGACGCGATCGAGAACATCACGCATTCGCTGTGCACGCTCGAGTTCGAAAACAACCGCCCGCTCTATGACTGGGT
GCTCGAGCACCTGCGCGACGCTGGCGTGTTCGCCAATCCGCTGCCGCATCAATACGAATTCGCGCGCCTGAACCTGACCT
ACGCGATCACCAGCAAGCGACGCCTGAAGCAGCTCGTGGACGAGCAGCGCGTGACCGGCTGGGACGATCCGCGGATGCCC
ACCATCGTCGGTATCCGCCGCCGCGGCTACACGCCCGAGTCGATCCAGCTCTTCTGCGATCGCGTGGGTGTGTCAAAGGC
CGATAGCTGGATCGACATGAGCACGCTCGAAGGCGCGGTCCGTGATGACCTCGACGCGCGGGCACCGCGCAGCGTTGCCG
TGCTGGACCCGCTCAAGCTGATCCTGGACAACTACCCGGAAGGCCAGAGCGAGGAATGCTCGGCGCCGGTGCACCCGAAG
CAGCCTGAAATGGGCCGCCGCGTGTTCCCGCTGTCGCGTGAGCTGTGGATCGAGCGCGAAGACTTCAACGAGAACCCGCC
GAAGGGCTACTTCCGTCTGTTCCCAGGCAACAAGGTGCGCCTGCGCTACGGTTATGTGATCGAATGCACCGGCGTCGACA
AGGATGCCGACGGCAACGTGATTGCCGTGCACGCGAACTACCTGCCGGAAACCAAGAGCGGCACGCCTGGCGCGGACAGC
GTAAAGGTCAAGGGCAACATCCACTGGGTCAGCGCGCCTCACGCGTGTGAAGCCGAAGTCCGCCTGTACGACCGTCTGTT
CAACGATCCGAACCCGGATGCCGGTGGCAAGAACTTCCTGGACGCGCTGAATCCGGAATCGAAGAAGGTCGTGACCGCCT
ATCTGGAGCCGGGCCTACGCGATGCCAAACCAGAGGACCGTTTCCAGTTCGAGCGGCACGGTTACTTCGTGGCGGACCGA
GTGGATTCGCAGCCGGGCAAGCCGGTGTTCAACCGCACGGTTGGACTCAAGGACAGCTGGGGCAAGTGA

Upstream 100 bases:

>100_bases
AAATCGCCCCATTCCACGGAACATCAGGACCGCAAACCGGGTCAATCCAGGCCCGGACCGTCCGCCCAAGCAATCGAGCC
GCCCCCGTTGCGGCGACAAC

Downstream 100 bases:

>100_bases
GCATGGCGCAAACCATTACTTTTCCGCTTGATCGCGAGTTCATCGCGCTGAATGACCTGCTGAAGCTTGCCGGCGTCTGC
GACAGTGGCGGTGCCGGCAA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MSHDTKPNDTPAASNFLRSIIDQDLATGTYAGRADKQGDPLPTVITRFPPEPNGYLHIGHAKSICVNFGLARDYAGRCHL
RFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSAQAGSTPHLYFASDYFDQLYKFAETLIERGVAYVDSQSAEQIAAMRGNF
SEPGKPSPFRDRSVEENLKLFREMRDGKYADGEHVLRAKIDMTAPNIVMRDPVLYRIRHAHHHRTGDKWCIYPMYDFTHC
ISDAIENITHSLCTLEFENNRPLYDWVLEHLRDAGVFANPLPHQYEFARLNLTYAITSKRRLKQLVDEQRVTGWDDPRMP
TIVGIRRRGYTPESIQLFCDRVGVSKADSWIDMSTLEGAVRDDLDARAPRSVAVLDPLKLILDNYPEGQSEECSAPVHPK
QPEMGRRVFPLSRELWIEREDFNENPPKGYFRLFPGNKVRLRYGYVIECTGVDKDADGNVIAVHANYLPETKSGTPGADS
VKVKGNIHWVSAPHACEAEVRLYDRLFNDPNPDAGGKNFLDALNPESKKVVTAYLEPGLRDAKPEDRFQFERHGYFVADR
VDSQPGKPVFNRTVGLKDSWGK

Sequences:

>Translated_582_residues
MSHDTKPNDTPAASNFLRSIIDQDLATGTYAGRADKQGDPLPTVITRFPPEPNGYLHIGHAKSICVNFGLARDYAGRCHL
RFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSAQAGSTPHLYFASDYFDQLYKFAETLIERGVAYVDSQSAEQIAAMRGNF
SEPGKPSPFRDRSVEENLKLFREMRDGKYADGEHVLRAKIDMTAPNIVMRDPVLYRIRHAHHHRTGDKWCIYPMYDFTHC
ISDAIENITHSLCTLEFENNRPLYDWVLEHLRDAGVFANPLPHQYEFARLNLTYAITSKRRLKQLVDEQRVTGWDDPRMP
TIVGIRRRGYTPESIQLFCDRVGVSKADSWIDMSTLEGAVRDDLDARAPRSVAVLDPLKLILDNYPEGQSEECSAPVHPK
QPEMGRRVFPLSRELWIEREDFNENPPKGYFRLFPGNKVRLRYGYVIECTGVDKDADGNVIAVHANYLPETKSGTPGADS
VKVKGNIHWVSAPHACEAEVRLYDRLFNDPNPDAGGKNFLDALNPESKKVVTAYLEPGLRDAKPEDRFQFERHGYFVADR
VDSQPGKPVFNRTVGLKDSWGK
>Mature_581_residues
SHDTKPNDTPAASNFLRSIIDQDLATGTYAGRADKQGDPLPTVITRFPPEPNGYLHIGHAKSICVNFGLARDYAGRCHLR
FDDTNPVKEDTEYVDSIIDAVHWLGFSWDSAQAGSTPHLYFASDYFDQLYKFAETLIERGVAYVDSQSAEQIAAMRGNFS
EPGKPSPFRDRSVEENLKLFREMRDGKYADGEHVLRAKIDMTAPNIVMRDPVLYRIRHAHHHRTGDKWCIYPMYDFTHCI
SDAIENITHSLCTLEFENNRPLYDWVLEHLRDAGVFANPLPHQYEFARLNLTYAITSKRRLKQLVDEQRVTGWDDPRMPT
IVGIRRRGYTPESIQLFCDRVGVSKADSWIDMSTLEGAVRDDLDARAPRSVAVLDPLKLILDNYPEGQSEECSAPVHPKQ
PEMGRRVFPLSRELWIEREDFNENPPKGYFRLFPGNKVRLRYGYVIECTGVDKDADGNVIAVHANYLPETKSGTPGADSV
KVKGNIHWVSAPHACEAEVRLYDRLFNDPNPDAGGKNFLDALNPESKKVVTAYLEPGLRDAKPEDRFQFERHGYFVADRV
DSQPGKPVFNRTVGLKDSWGK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=547, Percent_Identity=47.5319926873857, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI62241042, Length=534, Percent_Identity=35.2059925093633, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI1786895, Length=570, Percent_Identity=57.1929824561403, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=313, Percent_Identity=23.3226837060703, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=547, Percent_Identity=43.327239488117, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17511007, Length=520, Percent_Identity=31.1538461538462, Blast_Score=231, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6324742, Length=579, Percent_Identity=41.9689119170984, Blast_Score=421, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321192, Length=536, Percent_Identity=34.8880597014925, Blast_Score=289, Evalue=8e-79,
Organism=Drosophila melanogaster, GI17864488, Length=546, Percent_Identity=43.040293040293, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24649466, Length=529, Percent_Identity=32.8922495274102, Blast_Score=256, Evalue=4e-68,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 66122; Mature: 65991

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDTKPNDTPAASNFLRSIIDQDLATGTYAGRADKQGDPLPTVITRFPPEPNGYLHIGH
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEECC
AKSICVNFGLARDYAGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSAQAGSTPHL
HHEEHHHCCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
YFASDYFDQLYKFAETLIERGVAYVDSQSAEQIAAMRGNFSEPGKPSPFRDRSVEENLKL
EEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
FREMRDGKYADGEHVLRAKIDMTAPNIVMRDPVLYRIRHAHHHRTGDKWCIYPMYDFTHC
HHHHHCCCCCCCCEEEEEEEECCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEHHHHHHH
ISDAIENITHSLCTLEFENNRPLYDWVLEHLRDAGVFANPLPHQYEFARLNLTYAITSKR
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCHH
RLKQLVDEQRVTGWDDPRMPTIVGIRRRGYTPESIQLFCDRVGVSKADSWIDMSTLEGAV
HHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHH
RDDLDARAPRSVAVLDPLKLILDNYPEGQSEECSAPVHPKQPEMGRRVFPLSRELWIERE
HCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHEEECC
DFNENPPKGYFRLFPGNKVRLRYGYVIECTGVDKDADGNVIAVHANYLPETKSGTPGADS
CCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
VKVKGNIHWVSAPHACEAEVRLYDRLFNDPNPDAGGKNFLDALNPESKKVVTAYLEPGLR
EEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCC
DAKPEDRFQFERHGYFVADRVDSQPGKPVFNRTVGLKDSWGK
CCCCHHHHHHHHCCEEEEECCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
SHDTKPNDTPAASNFLRSIIDQDLATGTYAGRADKQGDPLPTVITRFPPEPNGYLHIGH
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEECC
AKSICVNFGLARDYAGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGFSWDSAQAGSTPHL
HHEEHHHCCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
YFASDYFDQLYKFAETLIERGVAYVDSQSAEQIAAMRGNFSEPGKPSPFRDRSVEENLKL
EEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
FREMRDGKYADGEHVLRAKIDMTAPNIVMRDPVLYRIRHAHHHRTGDKWCIYPMYDFTHC
HHHHHCCCCCCCCEEEEEEEECCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEHHHHHHH
ISDAIENITHSLCTLEFENNRPLYDWVLEHLRDAGVFANPLPHQYEFARLNLTYAITSKR
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCHH
RLKQLVDEQRVTGWDDPRMPTIVGIRRRGYTPESIQLFCDRVGVSKADSWIDMSTLEGAV
HHHHHHHHHCCCCCCCCCCCCEEEHHHCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHH
RDDLDARAPRSVAVLDPLKLILDNYPEGQSEECSAPVHPKQPEMGRRVFPLSRELWIERE
HCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHEEECC
DFNENPPKGYFRLFPGNKVRLRYGYVIECTGVDKDADGNVIAVHANYLPETKSGTPGADS
CCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
VKVKGNIHWVSAPHACEAEVRLYDRLFNDPNPDAGGKNFLDALNPESKKVVTAYLEPGLR
EEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCC
DAKPEDRFQFERHGYFVADRVDSQPGKPVFNRTVGLKDSWGK
CCCCHHHHHHHHCCEEEEECCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA