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The map label for this gene is 94309752

Identifier: 94309752

GI number: 94309752

Start: 883705

End: 884478

Strand: Direct

Name: 94309752

Synonym: Rmet_0807

Alternate gene names: NA

Gene position: 883705-884478 (Clockwise)

Preceding gene: 94309751

Following gene: 94309753

Centisome position: 22.5

GC content: 64.73

Gene sequence:

>774_bases
ATGTCTTTCGCCTTGCAGCCCGGCCGTGCCGCGGGCCCGGCTTTCCCGATCAGCGACGAAGAAGCGCGCGTGCGCGTGGA
CCTTGCCGCCGCCTACCGGCTAGCCGCGCTGGAGCGCTGGGATGACCTGATCTACACCCATATTTCGGCCACCGTGCCTG
GTGAACCCGATCACTTCCTGATCAATCCGTTTGGCTTTGCCTTCGAGGAGATTCGCGCGTCCGATCTCGTCAAGATCAAC
AGCCGGGGCGAAGTGGTCGGCGAAACCGTCCATCCCGTCAACGTGACAGGCTTTGCGCTGCACGGCGCAGTCCATGCGGC
CCGCCCCGATGCACACTGTGTGATGCACCTCCATAACACCGCTGGTATCGCGGTGTCGGCCCAGGCCGAGGGATTGCTGC
CGCTCTCGCAGCATGCGATGCGTTTCCACGGGCGGATTGCCTATCACGATTACGAAGGGCTGGCGTTCTCGCCGGCCGAG
GGCGGGCGGCTTACCGGGTCGCTGGGCGGGCACCCGGCCATGCTGCTGCGCAACCACGGCACGCTGACCGTGGGCCGCAC
GGTAGCGGAAGCCTACGTGTTGATGGCCACGCTGATCAAGGCGTGCGAGATCCAGCTCGGCGCGCAGCTCGGCAGCGCTA
CCGTCCAGCCGTCAGCGGCCATTGCGGACAAGACCTCTCTGCAGCTTTATGACGGTGGCGCCGTCGAGGGCGCGATGGAA
TGGCCCGCACTGCTGCGCAAACTCGATAAAATCGATCCCTCTTACAAGAACTGA

Upstream 100 bases:

>100_bases
ATGCCGGCGTCTGAGGACTGCGCTACAGTATCGGCTCCGCCGCTCACTCGACCGGACGCACCCGCGCAGGCGTTGCAGGG
CGGCGCGGAGCCTTTGCCCC

Downstream 100 bases:

>100_bases
CATTCCAAAGGAGTCACGAATGCCCACTTTCCACGTAGAAATGTTTGAAGGCCGCACCGTCGAGCAGAAGCGCAAGTTTG
TCGAGGAAGTTACCCGTGTC

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSFALQPGRAAGPAFPISDEEARVRVDLAAAYRLAALERWDDLIYTHISATVPGEPDHFLINPFGFAFEEIRASDLVKIN
SRGEVVGETVHPVNVTGFALHGAVHAARPDAHCVMHLHNTAGIAVSAQAEGLLPLSQHAMRFHGRIAYHDYEGLAFSPAE
GGRLTGSLGGHPAMLLRNHGTLTVGRTVAEAYVLMATLIKACEIQLGAQLGSATVQPSAAIADKTSLQLYDGGAVEGAME
WPALLRKLDKIDPSYKN

Sequences:

>Translated_257_residues
MSFALQPGRAAGPAFPISDEEARVRVDLAAAYRLAALERWDDLIYTHISATVPGEPDHFLINPFGFAFEEIRASDLVKIN
SRGEVVGETVHPVNVTGFALHGAVHAARPDAHCVMHLHNTAGIAVSAQAEGLLPLSQHAMRFHGRIAYHDYEGLAFSPAE
GGRLTGSLGGHPAMLLRNHGTLTVGRTVAEAYVLMATLIKACEIQLGAQLGSATVQPSAAIADKTSLQLYDGGAVEGAME
WPALLRKLDKIDPSYKN
>Mature_256_residues
SFALQPGRAAGPAFPISDEEARVRVDLAAAYRLAALERWDDLIYTHISATVPGEPDHFLINPFGFAFEEIRASDLVKINS
RGEVVGETVHPVNVTGFALHGAVHAARPDAHCVMHLHNTAGIAVSAQAEGLLPLSQHAMRFHGRIAYHDYEGLAFSPAEG
GRLTGSLGGHPAMLLRNHGTLTVGRTVAEAYVLMATLIKACEIQLGAQLGSATVQPSAAIADKTSLQLYDGGAVEGAMEW
PALLRKLDKIDPSYKN

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826323, Length=189, Percent_Identity=48.6772486772487, Blast_Score=171, Evalue=6e-43,
Organism=Homo sapiens, GI29826325, Length=189, Percent_Identity=48.6772486772487, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI29826321, Length=189, Percent_Identity=48.6772486772487, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI29826319, Length=189, Percent_Identity=48.6772486772487, Blast_Score=170, Evalue=9e-43,
Organism=Homo sapiens, GI9257190, Length=248, Percent_Identity=38.7096774193548, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI89276787, Length=248, Percent_Identity=38.7096774193548, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI297307160, Length=248, Percent_Identity=38.7096774193548, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI297307158, Length=248, Percent_Identity=38.7096774193548, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI9257192, Length=248, Percent_Identity=38.7096774193548, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI9943848, Length=250, Percent_Identity=36.4, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI9951927, Length=250, Percent_Identity=36.4, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI62912453, Length=250, Percent_Identity=36.4, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115533216, Length=249, Percent_Identity=38.5542168674699, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI115533218, Length=249, Percent_Identity=38.5542168674699, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71989560, Length=238, Percent_Identity=33.6134453781513, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71989544, Length=238, Percent_Identity=33.6134453781513, Blast_Score=131, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71989550, Length=238, Percent_Identity=33.6134453781513, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71989555, Length=238, Percent_Identity=33.6134453781513, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71989541, Length=238, Percent_Identity=33.6134453781513, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281363755, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281363751, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24655690, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24655685, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI281363763, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281363757, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI17136738, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281363761, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281363759, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281363753, Length=189, Percent_Identity=39.1534391534392, Blast_Score=127, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 27434; Mature: 27302

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFALQPGRAAGPAFPISDEEARVRVDLAAAYRLAALERWDDLIYTHISATVPGEPDHFL
CCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEE
INPFGFAFEEIRASDLVKINSRGEVVGETVHPVNVTGFALHGAVHAARPDAHCVMHLHNT
ECCHHHHHHHHCCCCEEEECCCCCEECCEECCCEEEEEEEECEEECCCCCCEEEEEEECC
AGIAVSAQAEGLLPLSQHAMRFHGRIAYHDYEGLAFSPAEGGRLTGSLGGHPAMLLRNHG
CCEEEECCCCCCCCHHHHHHHHCCEEEEEECCCCEECCCCCCEEEECCCCCCEEEEECCC
TLTVGRTVAEAYVLMATLIKACEIQLGAQLGSATVQPSAAIADKTSLQLYDGGAVEGAME
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCHHH
WPALLRKLDKIDPSYKN
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SFALQPGRAAGPAFPISDEEARVRVDLAAAYRLAALERWDDLIYTHISATVPGEPDHFL
CCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEE
INPFGFAFEEIRASDLVKINSRGEVVGETVHPVNVTGFALHGAVHAARPDAHCVMHLHNT
ECCHHHHHHHHCCCCEEEECCCCCEECCEECCCEEEEEEEECEEECCCCCCEEEEEEECC
AGIAVSAQAEGLLPLSQHAMRFHGRIAYHDYEGLAFSPAEGGRLTGSLGGHPAMLLRNHG
CCEEEECCCCCCCCHHHHHHHHCCEEEEEECCCCEECCCCCCEEEECCCCCCEEEEECCC
TLTVGRTVAEAYVLMATLIKACEIQLGAQLGSATVQPSAAIADKTSLQLYDGGAVEGAME
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCHHH
WPALLRKLDKIDPSYKN
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]